Gene

KWMTBOMO08535  Validated by peptides from experiments

Annotation

PREDICTED:_putative_oxidoreductase_GLYR1_homolog_isoform_X3_[Papilio_xuthus]

Location

Bomo_Chr14(-):12368141-12373908      View in EpiBrowser

Full name

Putative oxidoreductase GLYR1 homolog      

Alternative Name

Glyoxylate reductase 1 homolog
Nuclear protein NP60 homolog

Location in the cell

Cytoplasmic   Reliability : 2.305

CDS

ATGTGCAAAGACTTCGAGAAAGTTGGGGCCACGATTGCGGTGACACCATGCGATGTGGTGGAAGAAGCCGACATCACGTTCTCATGTGTGGCTGACCCTCAAGCAGCTAAAGAGATGGTGTTCGGTAATTGTGGCGTGCTGCACTGCCCGACGCTGGAGTCCAAGGGCTACGTCGAGATGACCTCGATCGACGCCGACACCTCGCACGACATCGTGGAAGCCATCAGCGGCAAGGGTGGCCGCTACCTGGAGGCCCAGATACAAGGATCGAAAACGCAAGCGGAGGAAGGCACGCTGATAGTGCTGGCGGCCGGCGACCGCTCGCTGTTCGACGACTGCCAGTCCTGCTTCAAGGCGATGAGCAAGAACTCGTTTTACCTTGGTAGTGAGATCGGCAACGCGTCGAAGATGAACTCCGTGCTGCAGGTGGTGGGCGGCGTGTCGCTGGCCGCGCTGGCCGAGGGGCTGGCGCTGGCCGACCGCGCGGGGCTCAGCCAGGCCGACCTGCTCGACGTGCTGGCCCTCACGCCGCTCGCCTCCCCGCACCTCATCCTCAAAGGACGCGCCATGATCGAGTCCTCCTACTCCACGCACCAGCCCCTCACGCACATGCAGAAGGACCTTAAGCTGGCGCTGGGGCTGGGCGACGCGCTGGAGCAGTCCCTGCCGCTCACGGCCACCACCAACGAGATCTTCAAGCACGCCAAGCGCCTCGGCTACGCGAACCACGACGTGGCCGCCGTCTACATCCGCGCCCGCTTCTGA

Protein

MCKDFEKVGATIAVTPCDVVEEADITFSCVADPQAAKEMVFGNCGVLHCPTLESKGYVEMTSIDADTSHDIVEAISGKGGRYLEAQIQGSKTQAEEGTLIVLAAGDRSLFDDCQSCFKAMSKNSFYLGSEIGNASKMNSVLQVVGGVSLAALAEGLALADRAGLSQADLLDVLALTPLASPHLILKGRAMIESSYSTHQPLTHMQKDLKLALGLGDALEQSLPLTATTNEIFKHAKRLGYANHDVAAVYIRARF

Description

May have oxidoreductase activity.

Miscellaneous

The conserved NAD-binding sites suggest that this protein may have oxidoreductase activity.

Similarity

Belongs to the HIBADH-related family. NP60 subfamily.

Keywords

Complete proteome   NAD   Oxidoreductase   Reference proteome  

Feature

chain  Putative oxidoreductase GLYR1 homolog

Uniprot

A0A212FPF0   A0A2A4JAC5   A0A2H1VKG6   A0A3S2M6T9   A0A0L7KJ14   A0A0N1IDA5   + More
A0A194Q8T3   A0A067QXW9   A0A1B6MMY6   A0A1B6KHL1   E9IKY4   A0A0L7RKQ1   A0A154NXM1   E2BGS6   A0A026W1K6   A0A1B6GI18   A0A088AUI9   A0A0J7KTK1   E9H752   E0VKD7   A0A1B6FJJ2   A0A195BT00   A0A195CIF2   A0A1B6CWT0   A0A195F314   A0A1S4ESI7   A0A232EL63   A0A423SFH2   A0A151J3H2   A0A0P5EUM9   A0A2A3ERD7   V9IAL3   A0A3L8D5T8   A0A0P4WCV3   A0A0P4W762   A0A0C9QUR3   A0A336LMM2   A0A158P1G7   A0A0P5HI90   A0A0P5QGV7   A0A0P5EAW3   A0A0P4WQ01   A0A0P6JJ89   A0A0P5TIF6   A0A182SZT5   A0A0P6BML2   K7J4H0   T1JPD6   A0A0K2TU36   A0A0N0BDT7   A0A1L8DAW2   A0A1B0D1N2   F4W9B8   A0A1B0CTI4   A0A182NAW7   A0A182W8V8   A0A084VWE3   A0A182HRD4   A0A182RRC7   A0A182XHU2   A0A182K4N2   A0A182QM25   A0A182VBT9   A0A0P5B673   A0A182TI87   A0A182LYP8   A0A182Y6D8   A0A0K8TN33   A0A453YVI5   A0A1Q3G210   A0A182PNH1   A0A1S4H2H3   A0A182KZ01   A0A182IWZ4   Q7Q161   A0A182HAH3   A0A443REM0   B0W036   A0A443S6D6   U5EZK8   A0A1S4FEC3   Q175F8   T1EAE6   A0A2M4A6P4   W5J4J7   A0A2M3Z2I2   A0A2P8Y0A6   A0A2J7PG37   A0A2M4BIM9   A0A1B6KTN4   A0A444SCD3   Q16LQ1   A0A293M635   A0A182F4C5   T1KD49   Q175A9   V5HVK5   A0A131Y2N9   A0A2R5L8C0   A0A1S4FEK4  

EC Number

1.-.-.-

Pubmed

22118469    26227816    26354079    24845553    21282665    20798317    + More
24508170    21292972    20566863    28648823    30249741    21347285    20075255    21719571    24438588    25244985    26369729    12364791    20966253    26483478    17510324    20920257    23761445    29403074    25765539   

EMBL

AGBW02002847    OWR55607.1    NWSH01002408    PCG68353.1    ODYU01003037    SOQ41313.1    + More
RSAL01000023    RVE52294.1    JTDY01009677    KOB63066.1    KQ459243    KPJ02449.1    KQ459337    KPJ01380.1    KK853227    KDR09657.1    GEBQ01002748    JAT37229.1    GEBQ01029020    JAT10957.1    GL764026    EFZ18698.1    KQ414572    KOC71326.1    KQ434778    KZC04367.1    GL448228    EFN85058.1    KK107488    EZA49908.1    GECZ01007685    JAS62084.1    LBMM01003337    KMQ93646.1    GL732599    EFX72461.1    DS235243    EEB13853.1    GECZ01019403    JAS50366.1    KQ976418    KYM89493.1    KQ977720    KYN00498.1    GEDC01019368    JAS17930.1    KQ981855    KYN34853.1    NNAY01003627    OXU19085.1    QCYY01003519    ROT62952.1    KQ980275    KYN17005.1    GDIQ01267025    JAJ84699.1    KZ288192    PBC34298.1    JR038208    AEY58158.1    QOIP01000012    RLU15847.1    GDRN01067921    JAI64295.1    GDRN01067922    JAI64294.1    GBYB01007492    GBYB01007494    JAG77259.1    JAG77261.1    UFQT01000023    SSX18021.1    ADTU01001056    ADTU01001057    ADTU01001058    ADTU01001059    ADTU01001060    ADTU01001061    GDIQ01227108    JAK24617.1    GDIQ01124086    JAL27640.1    GDIP01144090    JAJ79312.1    GDIP01252332    LRGB01000872    JAI71069.1    KZS15433.1    GDIQ01005978    JAN88759.1    GDIP01126305    JAL77409.1    GDIP01012526    JAM91189.1    JH431826    HACA01011540    CDW28901.1    KQ435850    KOX70904.1    GFDF01010486    JAV03598.1    AJVK01010334    AJVK01010335    GL888002    EGI69300.1    AJWK01027661    ATLV01017581    KE525174    KFB42287.1    APCN01001690    AXCN02000653    GDIP01188990    JAJ34412.1    AXCM01002228    GDAI01002062    JAI15541.1    AAAB01008980    GFDL01001212    JAV33833.1    JXUM01031210    KQ560913    KXJ80367.1    NCKU01000903    RWS13714.1    DS231816    EDS37608.1    NCKV01007112    RWS23106.1    GANO01000613    JAB59258.1    CH477401    GAMD01000497    JAB01094.1    GGFK01003089    MBW36410.1    ADMH02002138    ETN58343.1    GGFM01001964    MBW22715.1    PYGN01001092    PSN37676.1    NEVH01025635    PNF15293.1    GGFJ01003778    MBW52919.1    GEBQ01025161    JAT14816.1    SAUD01042376    RXG51069.1    CH477898    EAT35237.1    GFWV01011495    MAA36224.1    CAEY01002009    CH477404    EAT41622.1    GANP01004181    JAB80287.1    GEFM01003051    JAP72745.1    GGLE01001541    MBY05667.1   

Proteomes

UP000007151    UP000218220    UP000283053    UP000037510    UP000053268    UP000027135    + More
UP000053825    UP000076502    UP000008237    UP000053097    UP000005203    UP000036403    UP000000305    UP000009046    UP000078540    UP000078542    UP000078541    UP000079169    UP000215335    UP000283509    UP000078492    UP000242457    UP000279307    UP000005205    UP000076858    UP000075901    UP000002358    UP000053105    UP000092462    UP000007755    UP000092461    UP000075884    UP000075920    UP000030765    UP000075840    UP000075900    UP000076407    UP000075881    UP000075886    UP000075903    UP000075902    UP000075883    UP000076408    UP000075885    UP000075882    UP000075880    UP000007062    UP000069940    UP000249989    UP000285301    UP000002320    UP000288716    UP000008820    UP000000673    UP000245037    UP000235965    UP000288706    UP000069272    UP000015104   

PRIDE

Q175F8    V5HVK5   

Pfam

PF14833   NAD_binding_11        + More
PF03446   NAD_binding_2
PF00855   PWWP

Interpro

IPR036291   NAD(P)-bd_dom_sf        + More
IPR006115   6PGDH_NADP-bd       
IPR008927   6-PGluconate_DH-like_C_sf       
IPR015815   HIBADH-related       
IPR013328   6PGD_dom2       
IPR029154   NADP-bd       
IPR000313   PWWP_dom       
IPR035501   NP60_PWWP       
IPR002204   3-OH-isobutyrate_DH-rel_CS       

SUPFAM

SSF51735   SSF51735        + More
SSF48179   SSF48179       

Gene 3D

1.10.1040.10    

CDD

cd05836  N_Pac_NP60

ProteinModelPortal

A0A212FPF0   A0A2A4JAC5   A0A2H1VKG6   A0A3S2M6T9   A0A0L7KJ14   A0A0N1IDA5   + More
A0A194Q8T3   A0A067QXW9   A0A1B6MMY6   A0A1B6KHL1   E9IKY4   A0A0L7RKQ1   A0A154NXM1   E2BGS6   A0A026W1K6   A0A1B6GI18   A0A088AUI9   A0A0J7KTK1   E9H752   E0VKD7   A0A1B6FJJ2   A0A195BT00   A0A195CIF2   A0A1B6CWT0   A0A195F314   A0A1S4ESI7   A0A232EL63   A0A423SFH2   A0A151J3H2   A0A0P5EUM9   A0A2A3ERD7   V9IAL3   A0A3L8D5T8   A0A0P4WCV3   A0A0P4W762   A0A0C9QUR3   A0A336LMM2   A0A158P1G7   A0A0P5HI90   A0A0P5QGV7   A0A0P5EAW3   A0A0P4WQ01   A0A0P6JJ89   A0A0P5TIF6   A0A182SZT5   A0A0P6BML2   K7J4H0   T1JPD6   A0A0K2TU36   A0A0N0BDT7   A0A1L8DAW2   A0A1B0D1N2   F4W9B8   A0A1B0CTI4   A0A182NAW7   A0A182W8V8   A0A084VWE3   A0A182HRD4   A0A182RRC7   A0A182XHU2   A0A182K4N2   A0A182QM25   A0A182VBT9   A0A0P5B673   A0A182TI87   A0A182LYP8   A0A182Y6D8   A0A0K8TN33   A0A453YVI5   A0A1Q3G210   A0A182PNH1   A0A1S4H2H3   A0A182KZ01   A0A182IWZ4   Q7Q161   A0A182HAH3   A0A443REM0   B0W036   A0A443S6D6   U5EZK8   A0A1S4FEC3   Q175F8   T1EAE6   A0A2M4A6P4   W5J4J7   A0A2M3Z2I2   A0A2P8Y0A6   A0A2J7PG37   A0A2M4BIM9   A0A1B6KTN4   A0A444SCD3   Q16LQ1   A0A293M635   A0A182F4C5   T1KD49   Q175A9   V5HVK5   A0A131Y2N9   A0A2R5L8C0   A0A1S4FEK4  

PDB

2UYY     E-value=2.25774e-41,     Score=422

KEGG

101743921    no KO assigned | (RefSeq) putative oxidoreductase GLYR1 homolog

GO

GO:0016491   GO:0051287   GO:0050661   GO:0008679   GO:0004616   GO:0032008   GO:0032439   GO:0042632   GO:0043410   GO:0045121   GO:0016876   GO:0043039   GO:0055114  

Length:

254

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.23082

Exp number, first 60 AAs:

0

Total prob of N-in:

0.09522

outside

1  -  254

 

 

Pi

199.585372

Theta

147.352226

Tajima's D

1.076289

CLR

0.522448

CSRT

0.679366031698415

Interpretation

Uncertain