Gene

KWMTBOMO08436

Pre Gene Modal

BGIBMGA009410

Annotation

PREDICTED:_MIT_domain-containing_protein_1-like_[Bombyx_mori]

Location

Bomo_Chr14(+):9129372-9132280      View in EpiBrowser

Full name

MIT domain-containing protein 1      

Location in the cell

Nuclear   Reliability : 2.813

CDS

ATGAATATAGAGCACGCAGCTATAAACATATTGAAACGAGGAGTAGAATTAGACACAAAGAAACGATATACGGAAGCATTGGTGTGTTATCAAGAAGGACTACAGATTTTAGTCGATAAAATGAAAGGTGAACCTGATGAATCACTGAGGTCATATTTGAGGAAGAAAGTCGAGGAATACATGAATAGAGCTGAGACAATAAAAAAGTTAGTTTTGCAACAAAAGGAGGCCGGCCAATTTCATGAACAAATCCATATAGAGAACAATTCAATAGGGCATAGCTACAAAACACTTTTCGGGAGGTTCCTTGATGAAGATGTTCAATTTGTGATTGTCGAAGACCCATACATTAGGTATCATCATCAGTGTCAAAATTTTCTGAAGCTCTCGGAATTATTAGTAAGGTCATGTCCGAATCTTAGTTACATTGAACTCGTTACATCAAGTGATGTAAAGTCAGCGAACGATCAGAAGAATTGTTTTCATATCTTACAAAATGATTTGGGAAGACATAAAATTAAATTAACTGTCAAATATTCAGAAACCTTACATGATAGACAGATTATTTTGAGCTCCGGTTGGATCATCAAGATCGGACGAGGTCTAGACTACTTCAAGGCTCCGGAGAACAAATATTGTCTAGGAGTGTTCGAAATGGATCTAAGACCCTGTTTGGAGACAACAGTAGATATAGTACACTCAAAGAATGTGAGACAGATTCAAAGTTAA

Protein

MNIEHAAINILKRGVELDTKKRYTEALVCYQEGLQILVDKMKGEPDESLRSYLRKKVEEYMNRAETIKKLVLQQKEAGQFHEQIHIENNSIGHSYKTLFGRFLDEDVQFVIVEDPYIRYHHQCQNFLKLSELLVRSCPNLSYIELVTSSDVKSANDQKNCFHILQNDLGRHKIKLTVKYSETLHDRQIILSSGWIIKIGRGLDYFKAPENKYCLGVFEMDLRPCLETTVDIVHSKNVRQIQS

Description

Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT complexes. Seems not to be involved in endosomal transport (By similarity).
Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex.

Subunit

Homodimer. Interacts (via MIT domain) with CHMP1A, CHMP1B, CHMP2A and IST1 (By similarity).

Keywords

Cell cycle   Cell division   Complete proteome   Endosome   Membrane   Reference proteome   Transport   3D-structure  

Feature

chain  MIT domain-containing protein 1

Uniprot

A0A3S2NAY5   A0A2A4JD68   A0A0N1PHE4   I4DL84   A0A0N1IQ53   S4PCS5   + More
A0A212EPN3   A0A2H1WN17   A0A2J7RCC7   A0A1Y1LQ01   A0A067RHH2   A0A1B6MJ48   A0A0T6B3M4   A0A1B6JZA5   A0A1B6EP20   A0A0P6CU59   A0A0P6I584   A0A2R5LHG9   E0VDR7   A0A2A3EEB4   A0A088AAV4   A0A026W5N3   E2AE62   E9GDF0   A0A0U2IG43   A0A154PDC6   A0A1S3HL76   A0A1S3ISA8   A0A0J7KWS9   V5HSA8   A0A131XLW4   G3MFM5   H9JIQ9   A0A224YTJ2   A0A151I4G7   A0A158N9H1   V4A0Q1   E2BFI2   A0A2Y9D7L0   A0A2P8YMB6   A0A151II17   A0A195E1H1   A0A151JUZ5   A0A1A7XRQ0   A0A3Q1I6I2   W5LZZ4   K7J2G9   M4AAJ7   A0A023GGS9   A0A1S2ZN26   A0A232F3I6   F1STE3   G3TMX6   A0A131YLK7   A0A1A8END0   A0A2I4BHB3   F4X0U6   A0A315WN33   A0A1A8BT21   A0A151XGL5   A0A384BCG9   A0A1A8JHH5   A0A2Y9KE71   A0A1A7ZZM0   A0A2Y9FE96   A0A3Q2ECV2   Q5I0J5   A0A1A8L9J8   A0A1A8NBK9   Q8VDV8   A0A1A8UWU8   A0A1A8E376   G3I701   G3W3Z2   A0A2U3V9U8   A0A2Y9QAV3   A0A341BBQ2   A0A3Q2ZEB3   G5BMT0   M3YI44   L5KBR4   A0A340Y0V6   A0A3B3WQ57   A0A087YCR6   A0A2K6U0F6   A0A2K5E6X2   A0A1D2NCA6   A0A3Q3SI41   L8ITT2   E1BGA2   I3MP46   A0A2K6Q3R7   A0A2K5JL75   A0A3Q7Q9A2   A0A0M9A3V6   A0A3Q4GNL9   A0A2U3VXB9   A0A3Q0SVQ1   G1QNL1   A0A2K6E1R3  

Pubmed

26354079    22651552    23622113    22118469    28004739    24845553    + More
20566863    24508170    30249741    20798317    21292972    26621068    25765539    28049606    22216098    19121390    28797301    21347285    23254933    29403074    20075255    23542700    28648823    26830274    21719571    29703783    15489334    16141072    21183079    21804562    21709235    21993625    23258410    27289101    22751099    19393038    25362486    25186727   

EMBL

RSAL01000297    RVE42806.1    NWSH01001996    PCG69484.1    KQ458751    KPJ05305.1    + More
AK402052    BAM18674.1    KQ459986    KPJ18838.1    GAIX01004006    JAA88554.1    AGBW02013418    OWR43465.1    ODYU01009799    SOQ54459.1    NEVH01005885    PNF38491.1    GEZM01055246    JAV73067.1    KK852506    KDR22493.1    GEBQ01004011    JAT35966.1    LJIG01015974    KRT81994.1    GECU01003443    GECU01002819    JAT04264.1    JAT04888.1    GECZ01030104    JAS39665.1    GDIP01242670    GDIP01151952    GDIQ01088517    LRGB01000687    JAI80731.1    JAN06220.1    KZS16750.1    GDIQ01010277    JAN84460.1    GGLE01004803    MBY08929.1    DS235083    EEB11523.1    KZ288267    PBC30095.1    KK107429    QOIP01000014    EZA50921.1    RLU14924.1    GL438827    EFN68295.1    GL732540    EFX82490.1    KT754409    ALS04243.1    KQ434869    KZC09258.1    LBMM01002491    KMQ94753.1    GANP01007500    JAB76968.1    GEFH01000438    JAP68143.1    JO840676    AEO32293.1    BABH01032885    BABH01032886    GFPF01009781    MAA20927.1    KQ976461    KYM84724.1    ADTU01009652    KB202685    ESO88500.1    GL448037    EFN85504.1    PYGN01000495    PSN45397.1    KQ977545    KYN02046.1    KQ979814    KYN19000.1    KQ981713    KYN37358.1    HADW01019119    HADX01003474    SBP20519.1    AHAT01025113    GBBM01002251    JAC33167.1    NNAY01001033    OXU25406.1    AEMK02000020    GEDV01008374    JAP80183.1    HAEB01002148    SBQ48675.1    GL888503    EGI59926.1    NHOQ01000293    PWA31549.1    HADZ01006871    SBP70812.1    KQ982169    KYQ59451.1    HAED01022451    HAEE01006954    SBR09206.1    HADY01009779    SBP48264.1    BC088263    HAEF01003796    SBR41178.1    HAEH01001109    SBR66244.1    AK005342    AK171903    BC020137    HAEJ01011066    SBS51523.1    HAEA01012147    SBQ40627.1    JH001401    EGW10903.1    AEFK01127608    AEFK01127609    JH171109    GEBF01001700    EHB10591.1    JAO01933.1    AEYP01032843    KB030860    ELK08965.1    AYCK01006166    LJIJ01000093    ODN02894.1    JH880789    ELR58884.1    AGTP01088893    KQ435742    KOX76690.1    ADFV01117446   

Proteomes

UP000283053    UP000218220    UP000053268    UP000053240    UP000007151    UP000235965    + More
UP000027135    UP000076858    UP000009046    UP000242457    UP000005203    UP000053097    UP000279307    UP000000311    UP000000305    UP000076502    UP000085678    UP000036403    UP000005204    UP000078540    UP000005205    UP000030746    UP000008237    UP000248480    UP000245037    UP000078542    UP000078492    UP000078541    UP000265040    UP000018468    UP000002358    UP000002852    UP000079721    UP000215335    UP000008227    UP000007646    UP000192220    UP000007755    UP000075809    UP000261681    UP000248482    UP000248484    UP000265020    UP000002494    UP000000589    UP000001075    UP000007648    UP000245320    UP000248483    UP000252040    UP000264800    UP000006813    UP000000715    UP000010552    UP000265300    UP000261480    UP000028760    UP000233220    UP000233020    UP000094527    UP000261640    UP000009136    UP000005215    UP000233200    UP000233080    UP000286641    UP000053105    UP000261580    UP000245340    UP000261340    UP000001073    UP000233120   

PRIDE

H9JIQ9    F1STE3    Q5I0J5    Q8VDV8    G3I701   

Pfam

PF04212   MIT        + More
PF16565   MIT_C

Interpro

IPR038113   MIT_C_sf        + More
IPR007330   MIT       
IPR032341   MIT_C       
IPR036181   MIT_dom_sf       

SUPFAM

SSF116846   SSF116846       

Gene 3D

3.30.870.30    

ProteinModelPortal

A0A3S2NAY5   A0A2A4JD68   A0A0N1PHE4   I4DL84   A0A0N1IQ53   S4PCS5   + More
A0A212EPN3   A0A2H1WN17   A0A2J7RCC7   A0A1Y1LQ01   A0A067RHH2   A0A1B6MJ48   A0A0T6B3M4   A0A1B6JZA5   A0A1B6EP20   A0A0P6CU59   A0A0P6I584   A0A2R5LHG9   E0VDR7   A0A2A3EEB4   A0A088AAV4   A0A026W5N3   E2AE62   E9GDF0   A0A0U2IG43   A0A154PDC6   A0A1S3HL76   A0A1S3ISA8   A0A0J7KWS9   V5HSA8   A0A131XLW4   G3MFM5   H9JIQ9   A0A224YTJ2   A0A151I4G7   A0A158N9H1   V4A0Q1   E2BFI2   A0A2Y9D7L0   A0A2P8YMB6   A0A151II17   A0A195E1H1   A0A151JUZ5   A0A1A7XRQ0   A0A3Q1I6I2   W5LZZ4   K7J2G9   M4AAJ7   A0A023GGS9   A0A1S2ZN26   A0A232F3I6   F1STE3   G3TMX6   A0A131YLK7   A0A1A8END0   A0A2I4BHB3   F4X0U6   A0A315WN33   A0A1A8BT21   A0A151XGL5   A0A384BCG9   A0A1A8JHH5   A0A2Y9KE71   A0A1A7ZZM0   A0A2Y9FE96   A0A3Q2ECV2   Q5I0J5   A0A1A8L9J8   A0A1A8NBK9   Q8VDV8   A0A1A8UWU8   A0A1A8E376   G3I701   G3W3Z2   A0A2U3V9U8   A0A2Y9QAV3   A0A341BBQ2   A0A3Q2ZEB3   G5BMT0   M3YI44   L5KBR4   A0A340Y0V6   A0A3B3WQ57   A0A087YCR6   A0A2K6U0F6   A0A2K5E6X2   A0A1D2NCA6   A0A3Q3SI41   L8ITT2   E1BGA2   I3MP46   A0A2K6Q3R7   A0A2K5JL75   A0A3Q7Q9A2   A0A0M9A3V6   A0A3Q4GNL9   A0A2U3VXB9   A0A3Q0SVQ1   G1QNL1   A0A2K6E1R3  

PDB

2YMB     E-value=1.22796e-57,     Score=562

KEGG

101741293    no KO assigned | (RefSeq) MIT domain-containing protein 1-like

GO

GO:0019904   GO:0030496   GO:0019898   GO:0032091   GO:0035091   GO:0043231   GO:0061952   GO:0042803   GO:0031902   GO:0000281  

Subcellular location

Late endosome membrane   During cytokinesis, recruited to the midbody via interaction with CHMP1A. Interacts with membranes enriched in phosphoinositides (By similarity).   With evidence from 1 publications.
Midbody   During cytokinesis, recruited to the midbody via interaction with CHMP1A. Interacts with membranes enriched in phosphoinositides (By similarity).   With evidence from 1 publications.
Membrane   During cytokinesis, recruited to the midbody via interaction with CHMP1A. Interacts with membranes enriched in phosphoinositides (By similarity).   With evidence from 1 publications.

Length:

242

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0009

Exp number, first 60 AAs:

0

Total prob of N-in:

0.08595

outside

1  -  242

 

 

Pi

139.759175

Theta

131.47285

Tajima's D

0.12362

CLR

0.621462

CSRT

0.407929603519824

Interpretation

Uncertain