Gene

KWMTBOMO08418

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr14(-):8471180-8472712      View in EpiBrowser

Full name

ATP-dependent DNA helicase      

Location in the cell

Cytoplasmic   Reliability : 1.065 Mitochondrial   Reliability : 1.333 Nuclear   Reliability : 1.303

CDS

ATGCTCGGTAGTTCACCCTGGGACCTGGAGGCGGAGGCGCTCGCTGCCGATTACCGGTGGCGTAGCGACCTCCGCTCTAGGGGGGAAGGGCGCCCCAGCGAAGGTGTAGTTCGAGCGCGAAGGCTCCACTCTCGGCGGTCCGTGCTGGAGGCGTGGTCTCGCCGCTTGGCGGACCCGTCGGCCGGCCTCCGAACCGTCGAGGCGGTCCGCCCGGTTCTCGCGGACTGGGTGGGCCGCGACCGCGGATGCCTCACCTTCCGGCTAACGCAGATGCTTACCGGCCATGGTTGTTTCGGCCGGTACTTGCACAAGATAGCCGGAAGGGAACCGACGGCGCAGTGCCACCACTGCGCGGACCACGACGAGGAAGACACAGCGGAACACACGCTGGCGCGTTGCTCTGGATTCGACGAGCAACGCGCCGCCCTCGTCGCGGTCATAGGTGAGGACCTCTCGCTGCCGCGCGTCGTGGCTACGATGCTCGGCAGCGAGGCGTCCTGGAAGGCGATGCTCGACTTCTGCGAGTCCACCATCTCGCAGAAGGAGGCGGCGGAGCGAGAGAGGGAGAGCTCTTCCCTTTCCGCACCGATCCGTCGCCGTCGAGCCGGGGGCCGGAGGCGGGAATACGCCCGTACGTCCCGGCCCCTGTAG

Protein

MLGSSPWDLEAEALAADYRWRSDLRSRGEGRPSEGVVRARRLHSRRSVLEAWSRRLADPSAGLRTVEAVRPVLADWVGRDRGCLTFRLTQMLTGHGCFGRYLHKIAGREPTAQCHHCADHDEEDTAEHTLARCSGFDEQRAALVAVIGEDLSLPRVVATMLGSEASWKAMLDFCESTISQKEAAERERESSSLSAPIRRRRAGGRRREYARTSRPL

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate

Cofactor

FAD
Mg(2+)

Similarity

Belongs to the GMC oxidoreductase family.
Belongs to the helicase family.

Uniprot

Q5KTM7   Q868Q4   A0A2W1BDU5   A0A2W1B333   A0A0J7KCI1   A0A0J7K2M2   + More
A0A0J7N1D9   A0A2W1BSQ5   A0A3S2NGT9   Q8MY33   Q8MY31   Q8MY27   A0A0J7KJB9   A0A2W1C3J5   Q8MY35   A0A437BTM1   A0A3S2LNH8   A0A2H1VYR8   A0A2H1WNZ5   A0A3S2N998   A0A3L8DDS1   A0A0J7MZM4   A0A3S2PJK0   A0A0J7N7H9   A0A437AS17   A0A0J7MY07   A0A0J7KS67   O01419   A0A0J7KCQ3   A0A194R5D3   A0A0J7KT62   A0A3L8DDV9   A0A0J7KJ07   A0A0J7KIW1   A0A3L8D2G3   A0A0J7JZF7   A0A0J7NEG9   A0A0J7JZ13   A0A0J7KJG6   A0A3L8DY91   A0A0J7KFG9   A0A0J7KHX7  

EC Number

3.6.4.12

Pubmed

12644555    28756777    30249741    9092665    26354079   

EMBL

AB126050    BAD86650.1    AB090825    BAC57926.1    KZ150308    PZC71477.1    + More
KZ150386    PZC71062.1    LBMM01009501    KMQ88083.1    LBMM01016102    KMQ84557.1    LBMM01012027    KMQ86470.1    KZ149950    PZC76665.1    RSAL01000109    RVE47213.1    AB078930    BAC06454.1    AB078931    BAC06456.1    AB078935    BAC06462.1    LBMM01006538    KMQ90523.1    KZ149896    PZC78733.1    AB078929    BAC06452.1    RSAL01000009    RVE53812.1    RSAL01003504    RVE40273.1    ODYU01005282    SOQ45985.1    ODYU01009945    SOQ54696.1    RSAL01000481    RVE41577.1    QOIP01000009    RLU18544.1    LBMM01012957    LBMM01012956    KMQ85900.1    KMQ85901.1    RSAL01000014    RVE53298.1    LBMM01008861    KMQ88580.1    RSAL01001432    RVE40790.1    LBMM01014132    KMQ85305.1    LBMM01003679    KMQ93242.1    D85594    BAA19776.1    LBMM01009494    KMQ88097.1    KQ460685    KPJ12887.1    LBMM01003452    KMQ93523.1    QOIP01000010    RLU18098.1    LBMM01006662    KMQ90413.1    LBMM01006725    KMQ90373.1    QOIP01000031    RLU14697.1    LBMM01019838    KMQ83439.1    LBMM01006110    KMQ90925.1    LBMM01019839    KMQ83438.1    LBMM01006671    KMQ90407.1    QOIP01000002    RLU25407.1    LBMM01008349    KMQ88951.1    LBMM01007088    KMQ90053.1   

Proteomes

UP000036403    UP000283053    UP000279307    UP000053240   

PRIDE

Q5KTM7    Q868Q4    O01419   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF01553   Acyltransferase
PF01421   Reprolysin
PF00732   GMC_oxred_N
PF07776   zf-AD
PF00096   zf-C2H2
PF05970   PIF1
PF00059   Lectin_C
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR036691   Endo/exonu/phosph_ase_sf       
IPR005135   Endo/exonuclease/phosphatase       
IPR002123   Plipid/glycerol_acylTrfase       
IPR024079   MetalloPept_cat_dom_sf       
IPR001590   Peptidase_M12B       
IPR036188   FAD/NAD-bd_sf       
IPR012132   GMC_OxRdtase       
IPR000172   GMC_OxRdtase_N       
IPR012934   Znf_AD       
IPR013087   Znf_C2H2_type       
IPR036236   Znf_C2H2_sf       
IPR016187   CTDL_fold       
IPR010285   DNA_helicase_pif1-like       
IPR016186   C-type_lectin-like/link_sf       
IPR001304   C-type_lectin-like       
IPR018378   C-type_lectin_CS       
IPR027417   P-loop_NTPase       

SUPFAM

SSF56219   SSF56219        + More
SSF51905   SSF51905       
SSF57667   SSF57667       
SSF52540   SSF52540       
SSF56436   SSF56436       

Gene 3D

3.60.10.10     3.40.390.10     3.50.50.60     3.10.100.10    

ProteinModelPortal

Q5KTM7   Q868Q4   A0A2W1BDU5   A0A2W1B333   A0A0J7KCI1   A0A0J7K2M2   + More
A0A0J7N1D9   A0A2W1BSQ5   A0A3S2NGT9   Q8MY33   Q8MY31   Q8MY27   A0A0J7KJB9   A0A2W1C3J5   Q8MY35   A0A437BTM1   A0A3S2LNH8   A0A2H1VYR8   A0A2H1WNZ5   A0A3S2N998   A0A3L8DDS1   A0A0J7MZM4   A0A3S2PJK0   A0A0J7N7H9   A0A437AS17   A0A0J7MY07   A0A0J7KS67   O01419   A0A0J7KCQ3   A0A194R5D3   A0A0J7KT62   A0A3L8DDV9   A0A0J7KJ07   A0A0J7KIW1   A0A3L8D2G3   A0A0J7JZF7   A0A0J7NEG9   A0A0J7JZ13   A0A0J7KJG6   A0A3L8DY91   A0A0J7KFG9   A0A0J7KHX7  

PDB

4XVM     E-value=0.0607302,     Score=81

KEGG

101743871    no KO assigned | (RefSeq) uncharacterized LOC101743871

GO

GO:0003964   GO:0016746   GO:0016021   GO:0050660   GO:0016614  

Length:

216

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00222

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01113

outside

1  -  216

 

 

Pi

135.300779

Theta

74.186859

Tajima's D

1.796541

CLR

0.000695

CSRT

0.850157492125394

Interpretation

Uncertain