Gene

KWMTBOMO08411

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr14(-):8335593-8338792      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.721

CDS

ATGGCGCAAAAAGGTAGAGAAAAACCGTATTCCCTTACGTTAGCATTCTATAATGCTAACGGACTCGCGCGGCAACGCGATCAAATTTTTGAATTCCTCCGCGATAATCTTGTAGATATTCTATTAGTGCAGGAAACCTGTCTGAAGCCCTCGCGTCGCGACCCGAAAGTCGCGAATTACGTCATGGTTAGGAATGACAGACTCACCGCCTCCAAAGGCGGGACTGCCATTTACTATAGGCGGGCCCTGCACGTTGTCCCTCTCGATACTCCCTCGCTCTCACATATCGAGGCGTCAGTGTGCCGTATCTCGCTGACGGGACACCAGCCGATAGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTTCTGAGCAGTGACATCGAGTCACTGTTCGGCATGGGAGACTCTGTCTCCTTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGTACAAACGTTAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTCACCTTTGAAATAGTCGGTCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCATTGCTTAGGAACGTAACTCTGCGCTTGCGTTCCATCGAAGCAATGTCAGAGCTCGACTCAGACCACCGACCTGTCGTTATGCAGCTCGGTCGCCCTCACAACCCAGTCACTGTTACGAGGACCATGGTGGATTGGAATAAGCTGGGCACGTGCCTAGCCGACGCCGCTCCGCCAATCCTCCCTTACGGCCCGGATTCGAATCCATCCCCCGAGGACACCGTCGAATCCATAAACATCATTACCAATCACATCTCTTCCGCGATCATTAGATCTTCTAAAGAAGTCGATGTGGAGGACAGCTTCCACCGCATCAGACTGTCCCCCGATCTTAGGAATCTCTTAAGAGTTAGGAACGCGGCAATCCGGGCCTACGATCGTCTTCCCACGCATTCAAACCGGATTCAGATGCGTCGTCTACAACGCGAAGTCCACTCCCGCTTAAGCGACGCGCGTAACGATAATTGGCATAGTTATTTAGAACAACTCGCGCCCTCCCACCAAGCATACTGGCGACTAGCTAGGACTCTCAAATCCGAAACTACCGCTACTATGCCTCCCCTTTTACGCCCTTCAGGCCAACCGCCGGCATTCGATGACGATGACAAGGCTGAGCTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACTGACGAAGTTAGAGACGCGATCCACAACCTCCAACCTAGGAAGGCACCAGGCTCCGACGGCATCCACAACCGCGCGCTAAAATTTTTGCCAGTCCAACTGATAGCAATGTTGGCTACAATTTTAAATGCCGCTATGACGCACTGCATCTTTCCCGCGGTGTGGAAAGAAGCAGACGTTATCGGTATACATAAGCCGGGCAAACCGAGAAACGAAACCTCTAGTTACCGTCCGATTAGTCTCCTCTCGACGATAGGAAAAATTTACGAACGTCTCCTTAGGAAACGCCTCTGGGATTTTGTTACCGCGAACAAAATTCTCATAGACGAACAGTTCGGATTCCGCTCAAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATTCTAATAGGACTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGACATCGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTAATCTACAAACTGTACAACATGGGAGTGCCAGACGGACTCGTGCTCATCATACGAGACTTCTTGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCAACTGACTGCCGGAGTCCCGCAAGGCTCCGCGCTCTCCCCGTTATTATTTAGTTTGTATATCAATGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGCTGCTTCATTGGCGACTCCAGATCGCAGTAGCCACCATGGGACAGTGGTTCCGGAAGTGGCGAATAGACATCAACCCCACGAAAAGCGCAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAACATCACTTCGAGCATCCCACTCCGTAGTAGGCGCGCAAACACCTCCGCCGTTAGTCCCATCACTCTCTTTGGCCAGCCCATACCGTGGGTCTCGAAGGTCAAATATCTAGGCGTCACCCTCGACAGAGGGATGACATTCCGCCCCCATATAAAAACGGTACGCGACCGCGCCGCGTTTATTCTAGGACGACTCTATCCAATGCTTTGTAGTCGAAGCAAACTGTCCCTCCGCAATAAGGTAACTCTCTACAAAACTTGTATACGCCCCGTCATGACGTATGCAAGCGTAGTGTTCGCTCACTCAGCCCGCACCCACTTGAAATCCCTTCAGGTTATTCAATCACGATTCTGCAGGATAGCCGTCGGAGCGCCATGGTTCCTTAGGAATATGGATCTCCACGATGACCTGGAGCTCGACTCTCTTAGTAAGTATCTACAGTCGGCATCGCTGCGCCATTTTGAGAAGGCGGCACGACATGAGAACCCTCTCATCGTAGCCGCTGGAAATTACATACCCGACCCAGTAGACCGAATGGTAAACCGTCGACGTCGCCCAAAGCACGTCATTACGGATCCTCCTGATCCATTAACGGTGCTTTTAGGCACCACAAGCACCGGTCACCGTCCTCGTCGAACCCGTCGCTTGCGACGAAGGGCTCGACGAGCGAACTAA

Protein

MAQKGREKPYSLTLAFYNANGLARQRDQIFEFLRDNLVDILLVQETCLKPSRRDPKVANYVMVRNDRLTASKGGTAIYYRRALHVVPLDTPSLSHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVSLAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEIVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEAMSELDSDHRPVVMQLGRPHNPVTVTRTMVDWNKLGTCLADAAPPILPYGPDSNPSPEDTVESINIITNHISSAIIRSSKEVDVEDSFHRIRLSPDLRNLLRVRNAAIRAYDRLPTHSNRIQMRRLQREVHSRLSDARNDNWHSYLEQLAPSHQAYWRLARTLKSETTATMPPLLRPSGQPPAFDDDDKAELLADALQEQCTTSTQHADPEHTELVDREVERRASLPPSDALPPITTDEVRDAIHNLQPRKAPGSDGIHNRALKFLPVQLIAMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPRNETSSYRPISLLSTIGKIYERLLRKRLWDFVTANKILIDEQFGFRSKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDGLVLIIRDFLSNRSFRYRVEGTRSRPRQLTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKMSLLHWRLQIAVATMGQWFRKWRIDINPTKSAAVLFKRGRPPNITSSIPLRSRRANTSAVSPITLFGQPIPWVSKVKYLGVTLDRGMTFRPHIKTVRDRAAFILGRLYPMLCSRSKLSLRNKVTLYKTCIRPVMTYASVVFAHSARTHLKSLQVIQSRFCRIAVGAPWFLRNMDLHDDLELDSLSKYLQSASLRHFEKAARHENPLIVAAGNYIPDPVDRMVNRRRRPKHVITDPPDPLTVLLGTTSTGHRPRRTRRLRRRARRAN

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A2S2PPK8   D7EM17   A0A023EZE6   Q07995   A0A3N5Z7I3   X1WLB2   A0A2S2Q383   A0A2M4CV42   A0A2M4CV52   A0A2J7QR37   X1WNI2   A0A2M4BDA5   A0A2M4BD66   A0A087UGF5   A0A2M4BD62   A0A2J7PBY3   A0A2J7QY69   A0A224X6Q4   A0A2J7PU96   J9LC21   J9LFC9   A0A2S2QEE0   A0A2M4BD67   A0A2M4BDV6   A0A224XF24   A0A2J7Q6J2   A0A2J7R7D0   X1WZH0   V9GZF1   X1WQI9   A0A2S2N814   A0A2S2NGV8   A0A224X6T4   J9M522   A0A224XB44   A0A224X6S1   A0A069DZL8   A0A224X746   A0A224X6U5   J9KKL3   A0A2M4BEF4   A0A224XI99   A0A2M4BEZ9   A0A2J7RE85   A0A2H8TF37   K7IN67   Q8I7P8   A0A224X6R6   A0A2J7QB68   A0A1Y1KFR3   P21328   A0A2S2R9D4   A0A2S2P698   A0A2A4IUM2   A0A069DX78   A0A0A9YJ00   A0A0V0G5B6   A0A0A9YU04   A0A2J7PDM0   P21329   A0A2M4CVF1   A0A2M4CVK2   A0A2S2NPG3   A0A2J7PVX3   A0A224XJI0   A0A224XHW8   J9JS95   A0A1B6EGD8   A0A1Y1LKN6   A0A1W7R682   A0A2S2NJB5   A0A087UCW3   A0A0L0CBP5   A0A224X6W2   A0A1Y1K0C8   A0A2S2PJG2   Q8T9X4   Q95SX7   Q24335   V9H092   A0A2J7PQB5   A0A2S2PA10   J9KLB1   D7GYA5  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    8387152    30086797    1327974    26334808    20075255    2463954    3040362    1714378    25401762    1701254    26108605    7753626    12537569    2441397    9061921   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    KQ973412    EFA12510.2    GBBI01004571    JAC14141.1    S59870    AAB26437.2    RPOV01000134    RPJ78669.1    ABLF02042518    ABLF02057746    GGMS01002992    MBY72195.1    GGFL01005012    MBW69190.1    GGFL01004957    MBW69135.1    NEVH01011985    PNF31054.1    ABLF02008153    ABLF02008462    ABLF02008464    GGFJ01001842    MBW50983.1    GGFJ01001844    MBW50985.1    KK119692    KFM76444.1    GGFJ01001843    MBW50984.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    GFTR01008279    JAW08147.1    NEVH01021205    PNF19912.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    ABLF02023911    GGMS01006359    MBY75562.1    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    GFTR01008038    JAW08388.1    NEVH01017470    PNF24199.1    NEVH01006736    PNF36716.1    ABLF02034467    M95171    AAA29354.1    ABLF02022418    GGMR01000676    MBY13295.1    GGMR01003407    MBY16026.1    GFTR01008261    JAW08165.1    ABLF02024246    GFTR01008262    JAW08164.1    GFTR01008271    JAW08155.1    GBGD01000415    JAC88474.1    GFTR01008151    JAW08275.1    GFTR01008251    JAW08175.1    ABLF02029306    ABLF02029314    ABLF02060138    GGFJ01002256    MBW51397.1    GFTR01008256    JAW08170.1    GGFJ01002257    MBW51398.1    NEVH01005277    PNF39135.1    GFXV01000908    MBW12713.1    AY180919    AAN87272.1    GFTR01008269    JAW08157.1    NEVH01016302    PNF25823.1    GEZM01084969    JAV60363.1    M22874    M38643    GGMS01017365    MBY86568.1    GGMR01012305    MBY24924.1    NWSH01007753    PCG62823.1    GBGD01000389    JAC88500.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GECL01003538    JAP02586.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    NEVH01026386    PNF14434.1    M38437    GGFL01005122    MBW69300.1    GGFL01005121    MBW69299.1    GGMR01006408    MBY19027.1    NEVH01020940    PNF20481.1    GFTR01008257    JAW08169.1    GFTR01008254    JAW08172.1    ABLF02028535    ABLF02028545    GEDC01000337    JAS36961.1    GEZM01053022    JAV74219.1    GEHC01000968    JAV46677.1    GGMR01004661    MBY17280.1    KK119261    KFM75202.1    JRES01000644    KNC29657.1    GFTR01008260    JAW08166.1    GEZM01099921    GEZM01099920    GEZM01099918    GEZM01099906    JAV53125.1    GGMR01016905    MBY29524.1    AF456125    AAL57609.1    AY060438    AAL25477.1    M17214    AAA28508.1    L79944    AAB04627.1    NEVH01022639    PNF18527.1    GGMR01013409    MBY26028.1    ABLF02040174    ABLF02040183    ABLF02055266    KQ973363    EFA13335.2   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359    UP000002358    + More
UP000218220    UP000037069   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    Q8I7P8    P21328    P21329    + More
Q8T9X4    Q95SX7    Q24335   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       
IPR036875   Znf_CCHC_sf       
IPR001878   Znf_CCHC       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219        + More
SSF57756   SSF57756       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A2S2PPK8   D7EM17   A0A023EZE6   Q07995   A0A3N5Z7I3   X1WLB2   A0A2S2Q383   A0A2M4CV42   A0A2M4CV52   A0A2J7QR37   X1WNI2   A0A2M4BDA5   A0A2M4BD66   A0A087UGF5   A0A2M4BD62   A0A2J7PBY3   A0A2J7QY69   A0A224X6Q4   A0A2J7PU96   J9LC21   J9LFC9   A0A2S2QEE0   A0A2M4BD67   A0A2M4BDV6   A0A224XF24   A0A2J7Q6J2   A0A2J7R7D0   X1WZH0   V9GZF1   X1WQI9   A0A2S2N814   A0A2S2NGV8   A0A224X6T4   J9M522   A0A224XB44   A0A224X6S1   A0A069DZL8   A0A224X746   A0A224X6U5   J9KKL3   A0A2M4BEF4   A0A224XI99   A0A2M4BEZ9   A0A2J7RE85   A0A2H8TF37   K7IN67   Q8I7P8   A0A224X6R6   A0A2J7QB68   A0A1Y1KFR3   P21328   A0A2S2R9D4   A0A2S2P698   A0A2A4IUM2   A0A069DX78   A0A0A9YJ00   A0A0V0G5B6   A0A0A9YU04   A0A2J7PDM0   P21329   A0A2M4CVF1   A0A2M4CVK2   A0A2S2NPG3   A0A2J7PVX3   A0A224XJI0   A0A224XHW8   J9JS95   A0A1B6EGD8   A0A1Y1LKN6   A0A1W7R682   A0A2S2NJB5   A0A087UCW3   A0A0L0CBP5   A0A224X6W2   A0A1Y1K0C8   A0A2S2PJG2   Q8T9X4   Q95SX7   Q24335   V9H092   A0A2J7PQB5   A0A2S2PA10   J9KLB1   D7GYA5  

PDB

5HHL     E-value=0.00927553,     Score=96

KEGG

105842032    no KO assigned | (RefSeq) uncharacterized LOC105842032

GO

GO:0003964   GO:0004519   GO:0008270   GO:0003676   GO:0006313  

Length:

960

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.20325

Exp number, first 60 AAs:

0.00169

Total prob of N-in:

0.00618

outside

1  -  960

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0

CSRT

0

Interpretation

Uncertain