Gene

KWMTBOMO08369  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009221

Annotation

PREDICTED:_NADH_dehydrogenase_[ubiquinone]_complex_I?_assembly_factor_7_homolog_[Bombyx_mori]

Location

Bomo_Chr14(-):6948814-6952996      View in EpiBrowser

Full name

Protein arginine methyltransferase NDUFAF7       + More
Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial      
Protein arginine methyltransferase NDUFAF7, mitochondrial      

Alternative Name

NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 homolog
Protein midA homolog
NADH dehydrogenase [ubiquinone] complex I, assembly factor 7

Location in the cell

Cytoplasmic   Reliability : 4.025

CDS

ATGCCGACGCCGGAATCTGCTCCGAATTTAATAGAAATAATAAAAGAAAAAATAAGATTAAATGGACCTATAACTGTTGCTGAATATATGCATATAGTAACTACTAATCCTACCGAAGGGTATTATATGAAAAAGGAAGTAATTGGGGAAGCTGGTGATTTCATAACTTCACCGGAAATCAGTCAGCTATTTGGTGAAATTTTAGGTATTTGGTTTTATGCTGAAACACAGAAAATGTGTGAAGCGAAACCACTACAGATAGTTGAACTTGGTCCAGGAAAAGCAACATTACTAATTGATATGTTGAGGGTTCTCAATAAAATTGGCTATACATCACACGATTTAAGTATACACCTAGTAGAAATATCATCCACAATGCAATCTATTCAAGCTAACAGACTCTGTGTATCACATAGACCTGTAGAAATTGACATGCCACATAATCATGAGGGTGAAACACTCAGTGGTATCAAAGTATATTGGTATAATGATTTAAAGAAAGTACCACAAAACTTCTCATGGTATGTTGCACATGAATTTTTTGATGTCCTCCCCATACACAAGTTTGAAAAAACAGAAAAAGGTTGGAGAGAGCTTCTCATTGACATTGATGACACTGGAAAGCTGCTATACAGGTTGTCAGGTAATGAGACTCAGGCCGTGAAGATGCTTATTCGGCCACCCTTGGACTCTGGTGACAGAACAGAGTTAGAAATCAGTGCAAGAAGCTTGGGTGTAGCACGACAACTGGCTAAAAGGGTTGATGAGCATGGTGGTTTAGCGCTCATTGCTGATTATGGACATGAGGGTGAAAAGGGGGATACCTTTAGGGCTTTTCAAAAGCACCAAGTTGTAGATCCTCTTGAAACCCCAGGCAAGAGTGACTTGACTGCAGACGTTGACTTCTCACAACTTCGTATAGCCGCTTCAAAGACTCCTGGTGAAGAGAACTATGCACTAGTTGTTGGACCAGTAAAGCAAAAAGATTTTTTAGAACAATGCCAAGGGGAATTAAGGCTGCAGGTTCTTATTGACGCAGCAAAAAAAGATGAAGACAAAGAAAAGATAAAAAGCGCTTACGAAATGCTAGTCGATCCAAACAAAATGGGAGAAAGATTTAAATTTATGGCATTCTATCCTTCGACTATGGCGTCAATTCTTACAAAGTACCCACCCCTAGGTTTTTCAAATCTAAAACCATAG

Protein

MPTPESAPNLIEIIKEKIRLNGPITVAEYMHIVTTNPTEGYYMKKEVIGEAGDFITSPEISQLFGEILGIWFYAETQKMCEAKPLQIVELGPGKATLLIDMLRVLNKIGYTSHDLSIHLVEISSTMQSIQANRLCVSHRPVEIDMPHNHEGETLSGIKVYWYNDLKKVPQNFSWYVAHEFFDVLPIHKFEKTEKGWRELLIDIDDTGKLLYRLSGNETQAVKMLIRPPLDSGDRTELEISARSLGVARQLAKRVDEHGGLALIADYGHEGEKGDTFRAFQKHQVVDPLETPGKSDLTADVDFSQLRIAASKTPGEENYALVVGPVKQKDFLEQCQGELRLQVLIDAAKKDEDKEKIKSAYEMLVDPNKMGERFKFMAFYPSTMASILTKYPPLGFSNLKP

Description

Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of 'Arg-118' of ndufs2 after it assembles into the complex I, stabilizing the early intermediate complex.

Catalytic Activity

L-arginyl-[protein] + 2 S-adenosyl-L-methionine = 2 H(+) + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine

Similarity

Belongs to the NDUFAF7 family.

Keywords

Complete proteome   Methyltransferase   Mitochondrion   Reference proteome   Transferase   Transit peptide  

Feature

chain  Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial

Uniprot

H9JI73   A0A2W1BHI3   A0A2H1V8W4   A0A437BQ62   A0A437AYL2   A0A194PZT9   + More
A0A0N1IBB7   A0A1B0D2J8   A0A1B0D0A1   A0A2J7QT84   A0A146LLP0   R4G3P5   A0A1B6F0E7   E9H6Q3   A0A1J1IE57   A0A1B6IRF6   B4QU58   A0A162DAS8   A0A067R433   A0A0P5J5S4   A0A023F7E4   B5RJL4   Q9VGR2   B4HIC3   E0VC44   A0A0V0G7H4   A0A0P6BJX4   A0A0P6GTH0   D6WHT1   B4KCZ8   B3LZ53   A0A2I4CDN2   B4PM31   B3NZH3   A0A0P4VJQ0   A0A0R1E5F9   A0A1W4WVU7   A0A1W4U8A2   A0A0L0BNR0   A0A1I8MUC7   A0A0T6B3R5   B4JUV4   A0A1V9XN63   A0A1A9WU50   A0A1B0GCV7   D3TPZ2   B4GLH9   A0A1Y1MND4   A0A336LS35   Q293X3   A0A0M4F494   A0A1I8PCJ4   A0A1B0A3K0   A0A1S3W8N4   B4LZI3   K7FFM1   A0A1A9XU64   G1K9D5   A0A1A9VPH0   N6UAE6   A0A1L8G296   Q6GQ37   U4UD26   A0A3Q2ZCW2   H0ZE25   A0A1B0AVK5   A0A131Y4J2   A0A3Q2T8P0   A0A034VQP5   A0A146ZUV6   B0WMG6   W8CB54   A0A232F0R7   B7PSI0   U3KB55   F7DCQ0   Q5BKM6   A0A452J0J5   A0A3Q1GB09   A0A2I0USY5   W5PI51   A0A2P8YXQ7   A0A3Q3QLZ2   A0A023GNB0   A0A146Q5F2   A0A0K8R431   E1ZY58   A0A452FZV4   A0A2R5LM03   A0A452FZM5   A0A3B3UNH5   A0A3P9P8I1   A0A0N0BD78   A0A3Q3MY68   A0A087XB27   A0A3B0KBC8   M3ZZA9   A0A3Q1ARN5   A0A0Q3P520  

EC Number

2.1.1.320

Pubmed

19121390    28756777    26354079    26823975    21292972    17994087    + More
24845553    25474469    10731132    12537572    12537569    20566863    18362917    19820115    17550304    27129103    26108605    25315136    28327890    20353571    28004739    15632085    17381049    23537049    27762356    20360741    25348373    24495485    28648823    18464734    28562605    20809919    29403074    20798317    23542700   

EMBL

BABH01022341    KZ150057    PZC74298.1    ODYU01001285    SOQ37290.1    RSAL01000021    + More
RVE52547.1    RSAL01000269    RVE43209.1    KQ459585    KPI98259.1    KQ461193    KPJ07006.1    AJVK01022900    AJVK01002295    NEVH01011202    PNF31774.1    GDHC01010310    JAQ08319.1    ACPB03012381    GAHY01001481    JAA76029.1    GECZ01026436    JAS43333.1    GL732598    EFX72550.1    CVRI01000047    CRK98491.1    GECU01018223    JAS89483.1    CM000364    EDX13389.1    LRGB01002993    KZS05125.1    KK852771    KDR16883.1    GDIQ01204346    GDIQ01150680    JAK47379.1    JAL01046.1    GBBI01001554    JAC17158.1    BT044488    ACH95262.1    AE014297    AY060921    AY113468    BT012337    CH480815    EDW42638.1    DS235047    EEB10950.1    GECL01002042    JAP04082.1    GDIP01014772    JAM88943.1    GDIQ01028560    JAN66177.1    KQ971321    EFA00688.1    CH933806    EDW13768.1    CH902617    EDV42980.1    CM000160    EDW96897.1    CH954181    EDV49546.1    GDKW01002142    JAI54453.1    KRK03427.1    JRES01001582    KNC21725.1    LJIG01016063    KRT81725.1    CH916374    EDV91274.1    MNPL01007121    OQR74949.1    CCAG010002237    EZ423494    ADD19770.1    CH479185    EDW38403.1    GEZM01029761    JAV85945.1    UFQT01000097    SSX19781.1    CM000070    EAL29091.1    CP012526    ALC46512.1    CH940650    EDW67122.1    AGCU01167411    AGCU01167412    APGK01036659    KB740941    ENN77601.1    CM004475    OCT77995.1    BC072911    KB632225    ERL90228.1    ABQF01042392    JXJN01004287    GEFM01002820    JAP72976.1    GAKP01015064    JAC43888.1    GCES01016243    JAR70080.1    DS231997    EDS31023.1    GAMC01005131    JAC01425.1    NNAY01001377    OXU24182.1    ABJB010061739    DS778961    EEC09552.1    AGTO01000391    CR761995    BC091018    KZ505642    PKU49149.1    AMGL01078092    PYGN01000298    PSN49022.1    GBBM01001063    JAC34355.1    GCES01135108    JAQ51214.1    GADI01007888    JAA65920.1    GL435171    EFN73907.1    LWLT01000009    GGLE01006349    MBY10475.1    KQ435883    KOX69714.1    AYCK01019339    OUUW01000007    SPP83419.1    LMAW01002908    KQK75723.1   

Proteomes

UP000005204    UP000283053    UP000053268    UP000053240    UP000092462    UP000235965    + More
UP000015103    UP000000305    UP000183832    UP000000304    UP000076858    UP000027135    UP000000803    UP000001292    UP000009046    UP000007266    UP000009192    UP000007801    UP000192220    UP000002282    UP000008711    UP000192223    UP000192221    UP000037069    UP000095301    UP000001070    UP000192247    UP000091820    UP000092444    UP000008744    UP000001819    UP000092553    UP000095300    UP000092445    UP000079721    UP000008792    UP000007267    UP000092443    UP000001646    UP000078200    UP000019118    UP000186698    UP000030742    UP000264800    UP000007754    UP000092460    UP000265000    UP000002320    UP000215335    UP000001555    UP000016665    UP000002279    UP000008143    UP000291020    UP000257200    UP000002356    UP000245037    UP000261600    UP000000311    UP000291000    UP000261500    UP000242638    UP000053105    UP000261640    UP000028760    UP000268350    UP000002852    UP000257160    UP000051836   

PRIDE

H9JI73    B5RJL4    Q9VGR2    Q6GQ37    B7PSI0    Q5BKM6    + More

Pfam

PF02636   Methyltransf_28        + More
PF02207   zf-UBR
PF02617   ClpS
PF03152   UFD1

Interpro

IPR003788   NDUFAF7        + More
IPR038375   NDUFAF7_sf       
IPR029063   SAM-dependent_MTases       
IPR014719   Ribosomal_L7/12_C/ClpS-like       
IPR003769   ClpS_core       
IPR003126   Znf_UBR       
IPR004854   Ufd1-like       
IPR042299   Ufd1-like_Nn       

SUPFAM

SSF53335   SSF53335        + More
SSF54736   SSF54736       

Gene 3D

3.40.50.12710     2.40.40.50    

ProteinModelPortal

H9JI73   A0A2W1BHI3   A0A2H1V8W4   A0A437BQ62   A0A437AYL2   A0A194PZT9   + More
A0A0N1IBB7   A0A1B0D2J8   A0A1B0D0A1   A0A2J7QT84   A0A146LLP0   R4G3P5   A0A1B6F0E7   E9H6Q3   A0A1J1IE57   A0A1B6IRF6   B4QU58   A0A162DAS8   A0A067R433   A0A0P5J5S4   A0A023F7E4   B5RJL4   Q9VGR2   B4HIC3   E0VC44   A0A0V0G7H4   A0A0P6BJX4   A0A0P6GTH0   D6WHT1   B4KCZ8   B3LZ53   A0A2I4CDN2   B4PM31   B3NZH3   A0A0P4VJQ0   A0A0R1E5F9   A0A1W4WVU7   A0A1W4U8A2   A0A0L0BNR0   A0A1I8MUC7   A0A0T6B3R5   B4JUV4   A0A1V9XN63   A0A1A9WU50   A0A1B0GCV7   D3TPZ2   B4GLH9   A0A1Y1MND4   A0A336LS35   Q293X3   A0A0M4F494   A0A1I8PCJ4   A0A1B0A3K0   A0A1S3W8N4   B4LZI3   K7FFM1   A0A1A9XU64   G1K9D5   A0A1A9VPH0   N6UAE6   A0A1L8G296   Q6GQ37   U4UD26   A0A3Q2ZCW2   H0ZE25   A0A1B0AVK5   A0A131Y4J2   A0A3Q2T8P0   A0A034VQP5   A0A146ZUV6   B0WMG6   W8CB54   A0A232F0R7   B7PSI0   U3KB55   F7DCQ0   Q5BKM6   A0A452J0J5   A0A3Q1GB09   A0A2I0USY5   W5PI51   A0A2P8YXQ7   A0A3Q3QLZ2   A0A023GNB0   A0A146Q5F2   A0A0K8R431   E1ZY58   A0A452FZV4   A0A2R5LM03   A0A452FZM5   A0A3B3UNH5   A0A3P9P8I1   A0A0N0BD78   A0A3Q3MY68   A0A087XB27   A0A3B0KBC8   M3ZZA9   A0A3Q1ARN5   A0A0Q3P520  

PDB

5ZZW     E-value=2.30748e-60,     Score=589

KEGG

101742577    K18164 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7 | (RefSeq) NADH dehydrog

GO

GO:0008168   GO:0005739   GO:0030163   GO:0008270   GO:0032981   GO:0035243   GO:0019899   GO:0006511   GO:0019918   GO:0043009  

PANTHER

PTHR12049  

Subcellular location

Mitochondrion  

Length:

400

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.39273

Exp number, first 60 AAs:

0.0036

Total prob of N-in:

0.00213

outside

1  -  400

 

 

Pi

250.407617

Theta

204.623024

Tajima's D

0.820357

CLR

0

CSRT

0.608069596520174

Interpretation

Uncertain