Gene

KWMTBOMO08356  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009232

Annotation

PREDICTED:_aldose_1-epimerase_[Papilio_polytes]

Location

Bomo_Chr14(-):6479423-6486096      View in EpiBrowser

Full name

Aldose 1-epimerase      

Alternative Name

Galactose mutarotase

Location in the cell

Extracellular   Reliability : 1.917

CDS

ATGGTGACTTTGAATGTTGAGGATTTTGGACAGCATCATGGAGAGACGGTTTCAAAATTCACATGGAGGGCATCTGATGGCTTCTCAGTGTCCGTCATTTCATATGGGGCTACCATACAGTCAATTCAGGTACCGGACAAATACGGAATCACCAGTGACGTTGTTCTGGGCTTTGACGAACTCGACGGGTACGTGAACAGAAACACACCGTACTTAGGGACCACGGTCGGCCGCTGTGCCAACAGGATCGGCGGAGCAAAATTCAGCATCGACGGCACGACTTATCAACTCGCTAACAACATTGGGAAAGATCATTTACATGGCGGGATTAACGGATTTAATAAGGCGAATTGGAATTCCACCGTTGACGGTACTAAAGTGATATTTAGTTATCTATCAAAGGACGGCGAAGAAGGATACCCGGGTGATCTTATTACTAACATTACTTATGAAGTTACCGAGGACAATGCCTTGCATGTCGACTTTATGTCGACGACAACTAAAAAGACCGTTGTAAATCTGACAAACCATTCGTATTTTAATTTGGCTGGCCACGAAACTGGTGTCCAAGAGATCTACAACCATATCTTTGTTATAAACGCTGACAAGATCACGGAGACGGATTCTGGATCGATTCCGACTGGTGGTTTTATAAGCGTAGGAGGAACGCCCTACGATCTTCGCGTCCCAACTAAACTCGGCGACGTCATAAATAAAACTGGGAACGGTTTCGATGACAACTTCTGCATCTCAACGTACACAAATAAATCATTAAATTTCGTGTCTCGGATCCTTCATCCATCATCGGGACGCACTCTCGAAGTCTACAGCGATCAGCCCGGAGTCCAGTTTTACACCTCTAACTCCCTCCCTGCTCCTCAAGAGTCTGCTCTGGTTGGTAAACAGGGAGTTGGCTACAGACGTCACGGCGCGTTCTGTCTCGAGACCCAAAATTACCCGGACGCTGTCCATCACACGAATTTCCCGAGAGCAGTTCTGTATCCTGGCGAAGTGTATAAACATAAAGTGGTGTACAGATTTGCTGCTGCTGCTGCAGAAAAGCTGCAGTATCCTATTGTTTTGCCTGCGTGA

Protein

MVTLNVEDFGQHHGETVSKFTWRASDGFSVSVISYGATIQSIQVPDKYGITSDVVLGFDELDGYVNRNTPYLGTTVGRCANRIGGAKFSIDGTTYQLANNIGKDHLHGGINGFNKANWNSTVDGTKVIFSYLSKDGEEGYPGDLITNITYEVTEDNALHVDFMSTTTKKTVVNLTNHSYFNLAGHETGVQEIYNHIFVINADKITETDSGSIPTGGFISVGGTPYDLRVPTKLGDVINKTGNGFDDNFCISTYTNKSLNFVSRILHPSSGRTLEVYSDQPGVQFYTSNSLPAPQESALVGKQGVGYRRHGAFCLETQNYPDAVHHTNFPRAVLYPGEVYKHKVVYRFAAAAAEKLQYPIVLPA

Description

Converts alpha-aldose to the beta-anomer.

Catalytic Activity

alpha-D-glucose = beta-D-glucose

Similarity

Belongs to the aldose epimerase family.
Belongs to the peptidase C1 family.

Feature

chain  Aldose 1-epimerase

Uniprot

H9JI83   A0A3S2NIF1   A0A2W1BEF6   A0A0N1IEM2   A0A2H1VBA2   A0A212EZ93   + More
A0A2H1V8W8   A0A023ERU2   A0A084WTH2   A0A182GEB2   A0A182GGN4   A0A023ETD0   Q16SI6   A0A182IL09   A0A1Y1MZX9   A0A1S4FQS0   A0A1Y1N199   A0A182VDL1   A0A182KZV5   A0A182YJR4   A0A182W357   A0A182XF42   Q5TT05   A0A182FQE5   A0A182HVL0   A0A1Q3FR36   A0A182RI49   A0A182LTE1   A0A182JW77   A0A2M4BM71   W5JSN6   A0A2M4BLP1   A0A182NCS4   A0A182QY74   A0A1L8E1K3   A0A2M4BNQ6   B0W3B1   A0A1L8E1P9   A0A182SEM9   A0A182TQD7   A0A182PLE7   A0A2M4A711   A0A2M4A685   A0A2M4A6N3   A0A1B0GI99   A0A154PBN4   A0A1J1I063   E9IX12   E2BW64   V5GTG1   K7J742   A0A151I6V8   U4U9P8   A0A139WPN3   A0A194PY24   A0A336MR65   U5EP71   A0A336MNB8   A0A195B0P1   A0A151WS16   A0A195FBH6   A0A151JB89   A0A067R8C0   N6TS18   A0A2P8Y947   F4WWB1   A0A2J7QHX4   A0A3L8D803   A0A0M8ZP90   A0A026X2U9   A0A158NKI4   A0A0L7RDB7   D6WGD2   A0A139WPU0   A0A087ZNJ7   J3JUV0   A0A2J7QHY8   A0A2A3E2I6   N6TV79   E2AC71   A0A336LQN6   B4IZS5   B4LHE1   E0VPV6   C3Z3S8   A0A2M4CNH5   A0A0J7L5T4   A0A3B0KFK6   B4KWQ0   A0A1W4V9H2   A0A1S3H0U3   B4QJ93   A0A0L7K3R6   B4HUP1   A0A1I8PV53   A0A1B0CYR6   C5WLR2   Q8MT28   D3TPX1  

EC Number

5.1.3.3

Pubmed

19121390    28756777    26354079    22118469    24945155    24438588    + More
26483478    17510324    28004739    20966253    25244985    12364791    14747013    17210077    20920257    23761445    21282665    20798317    20075255    23537049    18362917    19820115    24845553    29403074    21719571    30249741    24508170    21347285    22516182    17994087    20566863    18563158    22936249    26227816    20353571   

EMBL

BABH01022310    RSAL01000028    RVE51845.1    KZ150356    PZC71230.1    KQ461193    + More
KPJ06986.1    ODYU01001628    SOQ38119.1    AGBW02011349    OWR46800.1    ODYU01001100    SOQ36852.1    GAPW01001690    JAC11908.1    ATLV01026892    KE525420    KFB53516.1    JXUM01057419    KQ561954    KXJ77062.1    JXUM01061998    KQ562178    KXJ76481.1    GAPW01001502    JAC12096.1    CH477673    EAT37419.1    GEZM01016664    JAV91209.1    GEZM01016665    JAV91208.1    AAAB01008898    EAL40526.3    APCN01005799    GFDL01005021    JAV30024.1    AXCM01001801    GGFJ01005004    MBW54145.1    ADMH02000200    ETN67387.1    GGFJ01004859    MBW54000.1    AXCN02001584    GFDF01001474    JAV12610.1    GGFJ01005267    MBW54408.1    DS231831    EDS31254.1    GFDF01001475    JAV12609.1    GGFK01003097    MBW36418.1    GGFK01002968    MBW36289.1    GGFK01003094    MBW36415.1    AJWK01013596    AJWK01013597    KQ434856    KZC08668.1    CVRI01000037    CRK93653.1    GL766616    EFZ14909.1    GL451091    EFN80096.1    GALX01004943    JAB63523.1    AAZX01002970    KQ978456    KYM93890.1    KYM93891.1    KB631843    ERL86660.1    KQ971307    KYB29856.1    KQ459585    KPI98241.1    UFQT01002209    SSX32932.1    GANO01000283    JAB59588.1    UFQT01001726    SSX31540.1    KQ976692    KYM77862.1    KQ982805    KYQ50465.1    KQ981693    KYN37773.1    KQ979182    KYN22340.1    KK852869    KDR14666.1    APGK01004458    APGK01004459    KB735765    ENN83304.1    PYGN01000790    PSN40786.1    GL888406    EGI61453.1    NEVH01013964    PNF28188.1    QOIP01000011    RLU16585.1    KQ438551    KOX67206.1    KK107021    EZA62346.1    ADTU01018854    KQ414614    KOC68795.1    KQ971329    EFA01124.1    KYB29855.1    BT127015    AEE61977.1    PNF28186.1    KZ288427    PBC25910.1    APGK01000121    KB741373    ENN70182.1    GL438428    EFN68965.1    UFQT01000108    SSX20115.1    CH916366    EDV95660.1    CH940647    EDW68471.1    DS235379    EEB15412.1    GG666577    EEN52842.1    GGFL01002702    MBW66880.1    LBMM01000640    KMQ97918.1    OUUW01000009    SPP85109.1    CH933809    EDW17497.1    CM000363    CM002912    EDX09402.1    KMY97861.1    JTDY01012359    KOB52288.1    CH480817    EDW50662.1    AJVK01020327    BT088877    ACS92849.1    AY118414    AAM48443.1    EZ423473    ADD19749.1   

Proteomes

UP000005204    UP000283053    UP000053240    UP000007151    UP000030765    UP000069940    + More
UP000249989    UP000008820    UP000075880    UP000075903    UP000075882    UP000076408    UP000075920    UP000076407    UP000007062    UP000069272    UP000075840    UP000075900    UP000075883    UP000075881    UP000000673    UP000075884    UP000075886    UP000002320    UP000075901    UP000075902    UP000075885    UP000092461    UP000076502    UP000183832    UP000008237    UP000002358    UP000078542    UP000030742    UP000007266    UP000053268    UP000078540    UP000075809    UP000078541    UP000078492    UP000027135    UP000019118    UP000245037    UP000007755    UP000235965    UP000279307    UP000053105    UP000053097    UP000005205    UP000053825    UP000005203    UP000242457    UP000000311    UP000001070    UP000008792    UP000009046    UP000001554    UP000036403    UP000268350    UP000009192    UP000192221    UP000085678    UP000000304    UP000037510    UP000001292    UP000095300    UP000092462   

PRIDE

H9JI83    C5WLR2    Q8MT28   

Pfam

PF01263   Aldose_epim        + More
PF00112   Peptidase_C1
PF08246   Inhibitor_I29

Interpro

IPR015443   Aldose_1-epimerase        + More
IPR014718   GH-type_carb-bd       
IPR011013   Gal_mutarotase_sf_dom       
IPR018052   Ald1_epimerase_CS       
IPR008183   Aldose_1/G6P_1-epimerase       
IPR000169   Pept_cys_AS       
IPR000668   Peptidase_C1A_C       
IPR039417   Peptidase_C1A_papain-like       
IPR038765   Papain-like_cys_pep_sf       
IPR025660   Pept_his_AS       
IPR013201   Prot_inhib_I29       

SUPFAM

SSF74650   SSF74650        + More
SSF54001   SSF54001       

Gene 3D

2.70.98.10    

CDD

cd02248  Peptidase_C1A

ProteinModelPortal

H9JI83   A0A3S2NIF1   A0A2W1BEF6   A0A0N1IEM2   A0A2H1VBA2   A0A212EZ93   + More
A0A2H1V8W8   A0A023ERU2   A0A084WTH2   A0A182GEB2   A0A182GGN4   A0A023ETD0   Q16SI6   A0A182IL09   A0A1Y1MZX9   A0A1S4FQS0   A0A1Y1N199   A0A182VDL1   A0A182KZV5   A0A182YJR4   A0A182W357   A0A182XF42   Q5TT05   A0A182FQE5   A0A182HVL0   A0A1Q3FR36   A0A182RI49   A0A182LTE1   A0A182JW77   A0A2M4BM71   W5JSN6   A0A2M4BLP1   A0A182NCS4   A0A182QY74   A0A1L8E1K3   A0A2M4BNQ6   B0W3B1   A0A1L8E1P9   A0A182SEM9   A0A182TQD7   A0A182PLE7   A0A2M4A711   A0A2M4A685   A0A2M4A6N3   A0A1B0GI99   A0A154PBN4   A0A1J1I063   E9IX12   E2BW64   V5GTG1   K7J742   A0A151I6V8   U4U9P8   A0A139WPN3   A0A194PY24   A0A336MR65   U5EP71   A0A336MNB8   A0A195B0P1   A0A151WS16   A0A195FBH6   A0A151JB89   A0A067R8C0   N6TS18   A0A2P8Y947   F4WWB1   A0A2J7QHX4   A0A3L8D803   A0A0M8ZP90   A0A026X2U9   A0A158NKI4   A0A0L7RDB7   D6WGD2   A0A139WPU0   A0A087ZNJ7   J3JUV0   A0A2J7QHY8   A0A2A3E2I6   N6TV79   E2AC71   A0A336LQN6   B4IZS5   B4LHE1   E0VPV6   C3Z3S8   A0A2M4CNH5   A0A0J7L5T4   A0A3B0KFK6   B4KWQ0   A0A1W4V9H2   A0A1S3H0U3   B4QJ93   A0A0L7K3R6   B4HUP1   A0A1I8PV53   A0A1B0CYR6   C5WLR2   Q8MT28   D3TPX1  

PDB

1SO0     E-value=3.17615e-70,     Score=673

KEGG

101741280    K01785 aldose 1-epimerase [EC:5.1.3.3] | (RefSeq) aldose 1-epimerase

PATHWAY

00010    Glycolysis / Gluconeogenesis - Bombyx mori (domestic silkworm)
00052    Galactose metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0004034   GO:0030246   GO:0019318   GO:0005975   GO:0008234   GO:0016853   GO:0033499   GO:0006006   GO:0005576   GO:0003824   GO:0051603   GO:0030145   GO:0006412   GO:0016876   GO:0043039  

Length:

363

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02724

Exp number, first 60 AAs:

0.02675

Total prob of N-in:

0.00566

outside

1  -  363

 

 

Pi

163.544111

Theta

19.802176

Tajima's D

-0.855667

CLR

2.949059

CSRT

0.168641567921604

Interpretation

Uncertain