Gene

KWMTBOMO08349

Pre Gene Modal

BGIBMGA009273

Annotation

PREDICTED:_transient-receptor-potential-like_protein_[Amyelois_transitella]

Location

Bomo_Chr14(+):6392687-6399534      View in EpiBrowser

Full name

Transient-receptor-potential-like protein      

Location in the cell

Cytoplasmic   Reliability : 2.652

CDS

ATGGCCGAGAAGAAGGATTTGGAAGCCGGCGACCCTGAATTGGAATGCGTCCGGAAACCAATGCCGTTACCGGTGCTCCCAAAACCACTTACTTTGGAAGAAAAGAAGTATTTGCTGGCAGTCGAGAGAGGAGATATGGCAAATGTGAGAAGATTACTCCAAAAAGGCCACCGCAAAAAACACATCGACATCAATTGCGTAGACTCTCTCGGTCGCGGGGCTTTGACCTTGTCAATTGACGGGGAGAACTTAGAGATGGTGGAACTCCTCGTCATCATGGGAGTGGAAACAAGAGACGCTTTGCTGCAAGCAATCAACGCGGAGTTTGTTGAAGCAGTTGAATTGTTACTAGAGCATGAAGAGTTAATTCACAAAGACGGTGAACCATACAGCTGGCAAAAAGTTGATCCAAACACAGCAATGTTCACTCCGGACATAACACCTCTGATGCTGGCGGCTCATAAGAACAACTATGAAATAATCAAGATACTTCTAGATCGTGGTGCCACTTTACCTAACCCTCATGACGTCAGATGTGGCTGCGAGGACTGTATCCGACAATCTACTGAGGACTCTCTGCGACACTCACTGGCACGCCTCAATGAATATCGAGCTTTGGCATCTCCGTCGCTCATAGCTCTGTCTTCTACAGATCCTATATTAACAGCCTTCGAATTGTCTTGGGAACTGAGGAATTTAGCCTTTGCTGAACAGGAAAGTAAAGCGGAATACCTGGAACTACGGAGACAGGCGCAACTGTTTGCTGTAGATCTGCTCGATCAATCCCGAAGCTCCCAAGAGCTGGCCATCATTCTCAATCATGATCCTGACGAACCAGCCTTTGTTGACGGAGAACACATGAAATTAGCACGTTTGGAATTGGCCATTGATTTTAAGCAGAAAAAGTTCGTAGCTCACCCTAACATCCAACAATTGCTGGCCTCTATCTGGTACGAAGGTGTCCCTGGATTCCGTCGTAAAACTACAATGGAGAAGATCATGATCATCTGTCGCGTCGCCCTATTGTTCCCTTTCTACTGCACTCTGTACATGATAGCCCCAAACTGCGCCACCGGAAAACTAATGAGGAAACCTTTCATGAAGTTCTTAATTCACGCTTCTAGTTACTTATTCTTTTTGTGTAAGTAA

Protein

MAEKKDLEAGDPELECVRKPMPLPVLPKPLTLEEKKYLLAVERGDMANVRRLLQKGHRKKHIDINCVDSLGRGALTLSIDGENLEMVELLVIMGVETRDALLQAINAEFVEAVELLLEHEELIHKDGEPYSWQKVDPNTAMFTPDITPLMLAAHKNNYEIIKILLDRGATLPNPHDVRCGCEDCIRQSTEDSLRHSLARLNEYRALASPSLIALSSTDPILTAFELSWELRNLAFAEQESKAEYLELRRQAQLFAVDLLDQSRSSQELAIILNHDPDEPAFVDGEHMKLARLELAIDFKQKKFVAHPNIQQLLASIWYEGVPGFRRKTTMEKIMIICRVALLFPFYCTLYMIAPNCATGKLMRKPFMKFLIHASSYLFFLCK

Description

A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Required for vision in the dark and in dim light. Binds calmodulin. Trp and trpl act together in the light response, although it is unclear whether as heteromultimers or distinct units. Also forms a functional cation channel with Trpgamma. Activated by fatty acids, metabolic stress, inositols and GTP-binding proteins.

Subunit

Forms heteromultimers with Trpgamma and, to a lower extent, with trp. Interacts with FKBP59 in vivo and is found in the inaD signaling complex.

Similarity

Belongs to the transient receptor (TC 1.A.4) family.
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.

Keywords

ANK repeat   Calcium   Calcium channel   Calcium transport   Calmodulin-binding   Complete proteome   Ion channel   Ion transport   Membrane   Reference proteome   Repeat   Sensory transduction   Transmembrane   Transmembrane helix   Transport   Vision  

Feature

chain  Transient-receptor-potential-like protein

Uniprot

H9JIC3   A0A2H1VKM1   A0A3S2NXY7   A0A2A4J1F1   A0A194PYX6   A0A0N1ICM2   + More
A0A212EM72   A0A182T045   Q179M5   A0A1Q3FS27   A0A1S4FB01   B0WEN0   A0A2M4BBT8   A0A2M4BCG6   Q7PTP0   A0A182JLW8   M4N9U7   D2A1G1   A0A084WLR8   W5J1J3   A0A182FTJ6   A0A182TQV7   A0A182VI22   A0A453Z0C9   A0A182LXL9   A0A182KUV4   A0A182X327   A0A182I0Y2   A0A182PBX0   A0A182QP93   A0A182YA85   A0A182RLY7   T1DPY1   A0A2M4A8K7   A0A2M4A834   A0A2M4A8I3   A0A2M4A843   T1H886   A0A182K248   A0A182WEB6   A0A182NPI7   A0A336L2Z3   A0A182G1G9   A0A182HA26   A0A384T274   A0A0K8SKT6   A0A1B6LZM0   A0A1J1IYR4   A0A0A9WXN9   A0A1B6EER2   A0A0L0C5K2   D3TKW3   A0A1A9X4C4   A0A0A1WZ79   A0A0K8WLZ2   A0A1W4UZP9   A0A067RIF5   T1PFK2   A0A034W307   A0A1I8N2Y0   W8ABV7   W8B6G5   A0A146LMA2   B3MCR1   A0A1I8P5H8   A0A1B0A2P7   P48994   B4HT37   A0A1B0BHH4   B3N6W7   A0A1A9V4N0   B4NWK1   A0A0R1DTT2   B4GGD2   A0A0R3NUP5   Q28Y01   A0A0R3NP54   A0A0R3NPZ4   B4MS74   A0A3B0J0C2   A0A0J9TXH9   A0A0J9R904   B4JVY3   B4LJB1   U4UIT9   A0A0Q9XAA9   B4KTU2   A0A1B0GFH5   A0A2H4WAN6   N6TP96   A0A0J9R907   W5JJ05   A0A0R3NVH0   A0A0P5U0B8   X1X233   A0A182HBB8   A0A0P5WTL1   A0A182MJ53   A0A0P5NIX2  

Pubmed

19121390    26354079    22118469    17510324    12364791    18362917    + More
19820115    24438588    20920257    23761445    20966253    25244985    26483478    25401762    26108605    20353571    25830018    24845553    25348373    25315136    24495485    26823975    17994087    18057021    1314616    10731132    12537572    12537569    8670063    9215637    9494079    10371201    9930700    10908615    8918461    10896160    11514552    11931743    11707492    17550304    15632085    23185243    22936249    23537049    29182505   

EMBL

BABH01022308    ODYU01003065    SOQ41367.1    RSAL01000028    RVE51848.1    NWSH01004108    + More
PCG65488.1    KQ459585    KPI98238.1    KQ459786    KPJ19920.1    AGBW02013881    OWR42592.1    CH477348    EAT42934.1    GFDL01004651    JAV30394.1    DS231910    EDS45746.1    GGFJ01001365    MBW50506.1    GGFJ01001367    MBW50508.1    AAAB01008796    EAA03611.5    KC292630    AGG86915.1    KQ971338    EFA02859.1    ATLV01024272    KE525351    KFB51162.1    ADMH02002175    ETN58052.1    AXCM01007166    APCN01006537    AXCN02001829    GAMD01002929    JAA98661.1    GGFK01003627    MBW36948.1    GGFK01003642    MBW36963.1    GGFK01003597    MBW36918.1    GGFK01003628    MBW36949.1    ACPB03011940    ACPB03011941    UFQS01001431    UFQT01001431    SSX10849.1    SSX30529.1    JXUM01136915    JXUM01136916    JXUM01136917    KQ568500    KXJ68981.1    JXUM01030796    KQ560896    KXJ80443.1    KX249689    AOR81466.1    GBRD01011882    JAG53942.1    GEBQ01010897    JAT29080.1    CVRI01000063    CRL04302.1    GBHO01030377    JAG13227.1    GEDC01000871    JAS36427.1    JRES01000890    KNC27516.1    EZ422050    ADD18473.1    GBXI01010130    GBXI01008708    GBXI01004578    JAD04162.1    JAD05584.1    JAD09714.1    GDHF01005173    GDHF01001552    GDHF01000136    JAI47141.1    JAI50762.1    JAI52178.1    KK852485    KDR22808.1    KA646945    AFP61574.1    GAKP01010448    GAKP01010447    JAC48505.1    GAMC01021170    JAB85385.1    GAMC01021171    JAB85384.1    GDHC01010100    JAQ08529.1    CH902619    EDV37313.1    KPU76709.1    KPU76710.1    M88185    AE013599    BT001397    BT099607    CH480816    EDW47147.1    JXJN01014362    JXJN01014363    CH954177    EDV58216.1    CM000157    EDW89546.1    KRJ98521.1    KRJ98522.1    CH479183    EDW35552.1    CM000071    KRT02893.1    EAL26165.2    KRT02894.1    KRT02892.1    KRT02895.1    CH963850    EDW74963.1    OUUW01000001    SPP74037.1    CM002911    KMY92564.1    KMY92565.1    KMY92566.1    KMY92562.1    CH916375    EDV98121.1    CH940648    EDW60491.1    KRF79437.1    KRF79438.1    KRF79439.1    KRF79440.1    KB632375    ERL93959.1    CH933808    KRG05424.1    EDW10668.1    CCAG010006888    MG020535    AUC64091.1    APGK01013995    APGK01013996    APGK01013997    APGK01013998    APGK01013999    APGK01014000    KB739168    ENN82359.1    KMY92563.1    ADMH02001356    ETN62865.1    KRT02896.1    GDIP01119518    JAL84196.1    ABLF02021769    ABLF02021770    ABLF02021771    ABLF02052683    JXUM01004958    JXUM01004959    JXUM01004960    JXUM01004961    JXUM01004962    KQ560184    KXJ83949.1    GDIP01094025    JAM09690.1    AXCM01012156    GDIQ01144554    JAL07172.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000053268    UP000053240    UP000007151    + More
UP000075901    UP000008820    UP000002320    UP000007062    UP000075880    UP000007266    UP000030765    UP000000673    UP000069272    UP000075902    UP000075903    UP000075883    UP000075882    UP000076407    UP000075840    UP000075885    UP000075886    UP000076408    UP000075900    UP000015103    UP000075881    UP000075920    UP000075884    UP000069940    UP000249989    UP000183832    UP000037069    UP000091820    UP000192221    UP000027135    UP000095301    UP000007801    UP000095300    UP000092445    UP000000803    UP000001292    UP000092460    UP000008711    UP000078200    UP000002282    UP000008744    UP000001819    UP000007798    UP000268350    UP000001070    UP000008792    UP000030742    UP000009192    UP000092444    UP000019118    UP000007819   

PRIDE

H9JIC3    P48994   

Pfam

PF00023   Ank        + More
PF08344   TRP_2
PF00520   Ion_trans
PF12796   Ank_2
PF13606   Ank_3

Interpro

IPR002110   Ankyrin_rpt        + More
IPR013555   TRP_dom       
IPR002153   TRPC_channel       
IPR005821   Ion_trans_dom       
IPR020683   Ankyrin_rpt-contain_dom       
IPR036770   Ankyrin_rpt-contain_sf       
IPR000435   Tektin       

SUPFAM

SSF48403   SSF48403       

Gene 3D

1.25.40.20    

CDD

cd00204  ANK

ProteinModelPortal

H9JIC3   A0A2H1VKM1   A0A3S2NXY7   A0A2A4J1F1   A0A194PYX6   A0A0N1ICM2   + More
A0A212EM72   A0A182T045   Q179M5   A0A1Q3FS27   A0A1S4FB01   B0WEN0   A0A2M4BBT8   A0A2M4BCG6   Q7PTP0   A0A182JLW8   M4N9U7   D2A1G1   A0A084WLR8   W5J1J3   A0A182FTJ6   A0A182TQV7   A0A182VI22   A0A453Z0C9   A0A182LXL9   A0A182KUV4   A0A182X327   A0A182I0Y2   A0A182PBX0   A0A182QP93   A0A182YA85   A0A182RLY7   T1DPY1   A0A2M4A8K7   A0A2M4A834   A0A2M4A8I3   A0A2M4A843   T1H886   A0A182K248   A0A182WEB6   A0A182NPI7   A0A336L2Z3   A0A182G1G9   A0A182HA26   A0A384T274   A0A0K8SKT6   A0A1B6LZM0   A0A1J1IYR4   A0A0A9WXN9   A0A1B6EER2   A0A0L0C5K2   D3TKW3   A0A1A9X4C4   A0A0A1WZ79   A0A0K8WLZ2   A0A1W4UZP9   A0A067RIF5   T1PFK2   A0A034W307   A0A1I8N2Y0   W8ABV7   W8B6G5   A0A146LMA2   B3MCR1   A0A1I8P5H8   A0A1B0A2P7   P48994   B4HT37   A0A1B0BHH4   B3N6W7   A0A1A9V4N0   B4NWK1   A0A0R1DTT2   B4GGD2   A0A0R3NUP5   Q28Y01   A0A0R3NP54   A0A0R3NPZ4   B4MS74   A0A3B0J0C2   A0A0J9TXH9   A0A0J9R904   B4JVY3   B4LJB1   U4UIT9   A0A0Q9XAA9   B4KTU2   A0A1B0GFH5   A0A2H4WAN6   N6TP96   A0A0J9R907   W5JJ05   A0A0R3NVH0   A0A0P5U0B8   X1X233   A0A182HBB8   A0A0P5WTL1   A0A182MJ53   A0A0P5NIX2  

PDB

6G1K     E-value=3.85762e-81,     Score=767

KEGG

101735306    K13803 transient-receptor-potential-like protein | (RefSeq) transient-receptor-potential-like protei

GO

GO:0005262   GO:0016021   GO:0006811   GO:0034703   GO:0006828   GO:0070679   GO:0005887   GO:0015279   GO:0051480   GO:0070588   GO:0016020   GO:0046982   GO:0030425   GO:0010461   GO:0005516   GO:0016027   GO:0007589   GO:0007605   GO:0042802   GO:0019722   GO:0035997   GO:0071454   GO:0007603   GO:0006812   GO:0050908   GO:0005886   GO:0006816   GO:0015075   GO:0005261   GO:0009416   GO:0016028   GO:0005515   GO:0005216   GO:0005839   GO:0051603   GO:0030145   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR10117  

Subcellular location

Membrane  

Length:

382

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

21.32642

Exp number, first 60 AAs:

0

Total prob of N-in:

0.68118

inside

1  -  334

TMhelix

335  -  357

outside

358  -  382

 

 

Pi

17.466273

Theta

160.515432

Tajima's D

0.201529

CLR

0.647108

CSRT

0.431878406079696

Interpretation

Uncertain