Silkworm Genome Informatics Database

Gene

KWMTBOMO08343 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009235

Annotation

PREDICTED:_alpha-N-acetylglucosaminidase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr14(-):6265102-6276656 View in EpiBrowser

Full name

Proteasome endopeptidase complex

Location in the cell

PlasmaMembrane Reliability : 1.257

CDS

ATGTTCAGGAACCAGTACGATAGCGACGTCACAGTATGGAGTCCTCAAGGCCGTCTCCATCAAGTGGAGTATGCAATGGAAGCTGTGAAACTTGGTTCTGCAACCATTGGTCTGAAGAATAAGGACTATGCGGTGTTGATAGCGTTGAAACGCGCTGTGAGCGAATTGTCCGCATATCAGAAGAAAATTATTCCTATTGATGAACATATTGGAATTTCTATATCAGGTCTTACTGCAGATGCTCGTATGCTGAGTCGCTACATGCGCACAGAGTGTCTCAATCACCGATATTCTCATGATGCTCCAATGCCCGTTGGACGTCTCATCTCGTCAGTTGGTAACAAAATGCAGATTTGTACCCAGAGATACGACAAGCGACCCTTGGGTGTGGGCTTGTTGGTTGCTGGTTATGATGACCAAGGACCTCATATTTACCAGACTTGTCCATCAGCCAACTACTTTGATTGTCGTGCGATGGCAATCGGAGCACGTTCGCAGTCAGCGCGTACTTATCTTGAGAAGCATCTCAATACATTCATGGATTGTGACCTTCAAGAGCTAGTAGCTCACGGTCTTAGAGCCCTACGGGATACGCTGCCAAATGAAGTTGATCTAAACACAAAGAATGTTTCTATATGTATCGTCGGTCCCAAGACTCCGTTGCGTATATGCGACGAGGAAGAGTTATCTCGACTGTTAGCTCTGGTCGAGGGTGAAGAGAGACGCGGCGGCACCGCGACCGGCGACGCGGGCGCTCCGGGAGGCGCCGCCCCGCGCGACCAGGGGGACGACCGGGACCCACAAGCGGCGAGTCAAATAGCGTGGCAAGTTCAACGAGTTGTGGTGCCGGAACCGCTCCCAGAAGTCGACGAACTTGTCGTTTCTAATGATAGATTTCGCTACTATCAAAACGTGTGCACGGCGTCTTATTCATTCGTTTGGTGGCAGACAAACGATTGGGTCGAACACGTCCAATGGATGGCACTGAATGGTATTAACTTAGCTTTAGCGCCAGTTGCACAGGAAGCGGCTTGGGCTCGCGTCTATCGCAGCCTCGGAATGACGGACGACGAAATAGATGAGCATTTTACCGGTCCCGCGTTTTTGGCTTGGCTTCGTATGGGGAATGTACACGGCTGGGGTGGACCACTCCTCAAGTCATGGAACGACAAACAAAGAGAAATTCAAGATTCCGTAATCGACTACATGTACCAGCTTGGCATTGTATCGGTCTTCCCGGCTTTCAATGGTCACGTACCGAAGGCATTTGCACGAATATTTCCGAATGTAACTTTTCACGACGTCGATACGTGGAATAAATTTGACGCTGAACATTGTTGTGGCTTGTTCGTAGATCCGAATGAACCACTTTTTAAAATAATAGGGAAAATGTTTTTAAAAGAAACTGGCAGTTTGTCAGCCACAAGTCACATTTACTCTTCGGACCCATTTAACGAGGTTAAAATTGAACAATGGTCAACAGCTTTGGTTGTGCAAACGGCCAAATCTATATTCTCGACATTATTAGAATTCGATGACGAAGCTGTCTGGTTATTGCAGAATTGGATGTTTGTTAGCGATCCGTTACAATGGCCTAAATCTAGGGTACGGTCATTTATGACGTCAGTGCCGAATGGTAGAATGTTGGTACTGGACCTTCAAGCGGAGCAGTGGCCACAATACGAACTTTACGAGATGTATTTCGGTCAACCATTCATATGGTGCATGTTACACAATTTTGGCGGAACTTTAGGGATGTTTGGTAACATGATAACGATCAATAAAGAAGTGTATTATGCACGGGCCCTCGCAAATAGCACAATGATTGGCGTCGGCCTTACCCCTGAAGGAATAAATCAGAATTATGTAGTTTACGATTTAATGTTGGAGTCAGCTTGGCGTAAGAAACCCGTAGAAAATCTCGATACTTGGGCAGGAGAATACGCGGAGCGAAGGTACGGTTGCAACACGACAACGGACGCCTGGCGGTATCTGTTAAAAAGCGTATACAGCTTCAATGGCTTGAACAAAGTCCGAGGGAAGTACGTAATCACTCGTAGGCCCAGTTTCAACATTAAGCCATGGGCTTGGTACAAAAGTTACGATCTATTCCAGGCTTTGAAAAAGTTTGTCACGAGTACAGATTGTTACTCCGATGGATTTCTATATGATATTGTTGATGTTACAAGGCAAGCGTTACAGTACAGGGCGGAACAACTATACGTAAATATGCAGAGCGCACGCTATTCCAACACTTTGTTGTTCAAAGAAGCGATACAACAATTTCTGGATGCCATGATTGATATAGAATCGATATTGCGGACAAATACGTTTTTCGGTGCAGCCGATTGGATCGCTAAAGCTGAGAATTTCGCGAGAACACCAATAGAATCGTATTCATATAGTTTGAATGCTCGCAATCAAATAACTCTGTGGGGCCCTAACGGGGAAATAACAGATTATGCATGCAAACAATGGGCTGAGCTATTCCACTATTATTACATTCCTAGATGGACAAAGTTCTTGGATGTTGCCCTCGATGCCAAAACGAAACGCGAAGTCTTCGACGAGAAAACTGCTCGGGATATGATTCGATCCACAGTCGAGTATAAATTTCTGTTTGTGACTTTCGACACTATCCATCGACCTGCGGTTAACCCGATAGATCTTGCTCTGGATCTGTACCAAAAATGGGCGTTTTATCCTGGTCTCGATGATCTGCCGCAAAACGTTATCCGCCCCGATCCTGGAAAGAGAACCACCCTGCCCGACGTTGATAAAGAAAGCGATGAGACAGAAGATCCCCCTTCCGTTATTATGTGGCACTCCACAACGCCGATCAATTAG

Protein

MFRNQYDSDVTVWSPQGRLHQVEYAMEAVKLGSATIGLKNKDYAVLIALKRAVSELSAYQKKIIPIDEHIGISISGLTADARMLSRYMRTECLNHRYSHDAPMPVGRLISSVGNKMQICTQRYDKRPLGVGLLVAGYDDQGPHIYQTCPSANYFDCRAMAIGARSQSARTYLEKHLNTFMDCDLQELVAHGLRALRDTLPNEVDLNTKNVSICIVGPKTPLRICDEEELSRLLALVEGEERRGGTATGDAGAPGGAAPRDQGDDRDPQAASQIAWQVQRVVVPEPLPEVDELVVSNDRFRYYQNVCTASYSFVWWQTNDWVEHVQWMALNGINLALAPVAQEAAWARVYRSLGMTDDEIDEHFTGPAFLAWLRMGNVHGWGGPLLKSWNDKQREIQDSVIDYMYQLGIVSVFPAFNGHVPKAFARIFPNVTFHDVDTWNKFDAEHCCGLFVDPNEPLFKIIGKMFLKETGSLSATSHIYSSDPFNEVKIEQWSTALVVQTAKSIFSTLLEFDDEAVWLLQNWMFVSDPLQWPKSRVRSFMTSVPNGRMLVLDLQAEQWPQYELYEMYFGQPFIWCMLHNFGGTLGMFGNMITINKEVYYARALANSTMIGVGLTPEGINQNYVVYDLMLESAWRKKPVENLDTWAGEYAERRYGCNTTTDAWRYLLKSVYSFNGLNKVRGKYVITRRPSFNIKPWAWYKSYDLFQALKKFVTSTDCYSDGFLYDIVDVTRQALQYRAEQLYVNMQSARYSNTLLFKEAIQQFLDAMIDIESILRTNTFFGAADWIAKAENFARTPIESYSYSLNARNQITLWGPNGEITDYACKQWAELFHYYYIPRWTKFLDVALDAKTKREVFDEKTARDMIRSTVEYKFLFVTFDTIHRPAVNPIDLALDLYQKWAFYPGLDDLPQNVIRPDPGKRTTLPDVDKESDETEDPPSVIMWHSTTPIN

Catalytic Activity

Cleavage of peptide bonds with very broad specificity.

Similarity

Belongs to the peptidase T1A family.

Uniprot

H9JI86 S4NNH4 A0A194R8C4 A0A194PY25 A0A0L7L8H5 A0A2H1WGV2 + More
A0A2A4IUB9 A0A2W1BNB9 A0A1W4WK47

EC Number

3.4.25.1

Pubmed

19121390 23622113 26354079 26227816 28756777

EMBL

BABH01022300 GAIX01012254 JAA80306.1 KQ460627 KPJ13505.1 KQ459585 + More
KPI98232.1 JTDY01002246 KOB71807.1 ODYU01008554 SOQ52257.1 NWSH01006661 PCG63311.1 KZ150121 PZC73173.1

Proteomes

UP000005204 UP000053240 UP000053268 UP000037510 UP000218220 UP000192223 + More

PRIDE

H9JI86

Pfam

PF12972   NAGLU_C        + More
PF05089   NAGLU
PF12971   NAGLU_N
PF10584   Proteasome_A_N
PF00227   Proteasome

Interpro

IPR007781   NAGLU        + More
IPR024240   NAGLU_N
IPR024733   NAGLU_tim-barrel
IPR029018   Hex-like_dom2
IPR024732   NAGLU_C
IPR023332   Proteasome_alpha-type
IPR035144   Proteasome_alpha1
IPR001353   Proteasome_sua/b
IPR029055   Ntn_hydrolases_N
IPR000426   Proteasome_asu_N

SUPFAM

SSF56235 SSF56235

Gene 3D

3.30.379.10 3.60.20.10

CDD

cd03749 proteasome_alpha_type_1

ProteinModelPortal

H9JI86 S4NNH4 A0A194R8C4 A0A194PY25 A0A0L7L8H5 A0A2H1WGV2 + More
A0A2A4IUB9 A0A2W1BNB9 A0A1W4WK47

PDB

4XWH E-value=1.47494e-137, Score=1258

KEGG

101739990 K02725 20S proteasome subunit alpha 6 [EC:3.4.25.1] | (RefSeq) proteasome subunit alpha type-1

PATHWAY

03050 Proteasome - Bombyx mori (domestic silkworm)

GO

GO:0005737 GO:0005634 GO:0004298 GO:0006511 GO:0019773 GO:0004175 GO:0005839 GO:0051603 GO:0030145 GO:0006412 GO:0016876 GO:0043039

PANTHER

PTHR12872

Subcellular location

Nucleus

Length:

948

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.501479999999999

Exp number, first 60 AAs:

0.00046

Total prob of N-in:

0.00121

outside

1 - 948

Pi

220.265043

Theta

180.395712

Tajima's D

0.601653

CLR

0.459335

CSRT

0.548272586370681

Interpretation

Uncertain

Source	Sequence	Identity	Evalue
28556443	GGTATGDAGAPGGAAPR	100.00	5e-08
26822097	DTIPNEVDINTK	100.00	4e-04
26280517	NQIDCPVICK	100.00	4e-04
25044914	NQVTGEYGPVPATAR	100.00	4e-04
24402669	NQVAMNPNNTIFDAK	100.00	4e-04
27102218	IIAIVEGEER	100.00	4e-04
28467696	NQVTGEYGPVPATAR	100.00	4e-04
28556443	HLNTFMDCDLQELVAHGLR	100.00	4e-04
26280517	TNIEHEYIQNFK	100.00	0.020
25044914	TNSVMSIVDR	100.00	0.020
24402669	TNQQFTITEIEDPNASTDSQKPECKPTK	100.00	0.020

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics