Silkworm Genome Informatics Database

Gene

KWMTBOMO08318 Validated by peptides from experiments

Annotation

PREDICTED:_uncharacterized_protein_LOC105842476_[Bombyx_mori]

Location

Bomo_Chr14(+):5301875-5307157 View in EpiBrowser

Full name

Fibrohexamerin

Alternative Name

25 kDa silk glycoprotein
p25

Location in the cell

Nuclear Reliability : 1.535 PlasmaMembrane Reliability : 1.187

CDS

ATGAAGTTAATGCTGTGTTTATGTCTTCTTTCGTTTTTCGGCTTGACTGTGGCGGATGAGGTAGACTGTGAATCTGATCTAGATCCGGCCGATGATCCGAGGAATATCGAAAGACCTTGTCCGAACTTCGACTTGGACTGTATTCGTAAATATTTCTCGAGTAATTCGAAATGTCAAATAACGCTGGGGCCAGTACCGGATCCGCTGCTTCTCAACAATTACAGATTAGATATAGCAAACTCTAATATTACCGCCCAATTTAACAACGTAAGCGTTCGAGGTCTCAATGGGAATATCGTTGAATTTTACATCAACAGAAAAACTGAGAAACTGGTTCTCGCAACAGAAGTGAAAAGCTTAGCATTTGATTCTCCACAGGTGGTATTTAAATACAACAGGAAAGGTAAAGAGCCCATTGTACGAGGTGACTGTGTGGATTGTGAATACGGAGCTGCAACTTTCACTGCTGTATTTCCAAGTATCTGCGATTTAGATCTGAGCAAAGCTGAAGTTTTCACCTACGTCGAAGACTCTAATCCCAGATATAAAATAGGATCACGACTATTTTCCATTTCTGATTCTGTGGCACTAAACGAGTTCCTAAAGTTTATAACGAGTATGTCGGAAAATATTCAAGAAAAGTTTATCTCGCAAGGAAGAATTTTTATGGCCAACTACATAGAATATAATATCTGTGACTTTGGATTAAATTTAGCATGTAAATAA

Protein

MKLMLCLCLLSFFGLTVADEVDCESDLDPADDPRNIERPCPNFDLDCIRKYFSSNSKCQITLGPVPDPLLLNNYRLDIANSNITAQFNNVSVRGLNGNIVEFYINRKTEKLVLATEVKSLAFDSPQVVFKYNRKGKEPIVRGDCVDCEYGAATFTAVFPSICDLDLSKAEVFTYVEDSNPRYKIGSRLFSISDSVALNEFLKFITSMSENIQEKFISQGRIFMANYIEYNICDFGLNLACK

Subunit

Silk fibroin elementary unit consists in a disulfide-linked heavy and light chain and a p25 glycoprotein in molar ratios of 6:6:1. This results in a complex of approximately 2.3 MDa.

Miscellaneous

It is unclear whether the N-terminal residue of the mature protein is Ala-17 or Gly-18.

Keywords

Complete proteome Direct protein sequencing Disulfide bond Glycoprotein Reference proteome Secreted Signal Silk protein

Feature

chain Fibrohexamerin

Uniprot

H9JIB1 H9JIA9 A0A0M4UR85 A0A0M3VH85 A0A2W1BYP1 A0A0M4U1I3 + More
A0A2A4J112 A0A0L7L2A8 A0A2W1BSA2 A0A2W1BS92 A0A0L7L1X1 Q9BLL8 P04148 A0A2A4JH46 Q9BLL6 Q14UU6 H9IVR6 A0A1V0PND8 D0EWD9 O62605 A0A437BH48

Pubmed

19121390 28756777 26227816 11267905 3748814 14614147 + More
15141943 2987837 10986287 16755355 20171223 9520260 9583947 7715595

EMBL

BABH01022228 BABH01022225 LC001863 BAS31051.1 LC001864 BAS31052.1 + More
KZ149916 PZC77940.1 LC001865 BAS31053.1 NWSH01003760 PCG65847.1 JTDY01003497 KOB69466.1 PZC77938.1 PZC77939.1 KOB69467.1 AB001821 BAB39500.1 X04226 BP122961 BP126317 BP177743 BAAB01057839 NWSH01001474 PCG71139.1 AB001823 BAB39502.1 AB195976 BAE97692.1 BABH01038094 BABH01038095 KY792994 ARE31005.1 GQ901976 ACX50393.1 AF009827 AF009677 RSAL01000058 RVE49720.1

Proteomes

UP000005204 UP000218220 UP000037510 UP000283053

PRIDE

H9JIB1 H9JIA9 Q9BLL8 P04148 Q9BLL6 H9IVR6 + More

Pfam

PF07294 Fibroin_P25

Interpro

IPR009911 Fibroin_P25 + More
IPR038606 To_sf

Gene 3D

3.15.10.30

ProteinModelPortal

H9JIB1 H9JIA9 A0A0M4UR85 A0A0M3VH85 A0A2W1BYP1 A0A0M4U1I3 + More
A0A2A4J112 A0A0L7L2A8 A0A2W1BSA2 A0A2W1BS92 A0A0L7L1X1 Q9BLL8 P04148 A0A2A4JH46 Q9BLL6 Q14UU6 H9IVR6 A0A1V0PND8 D0EWD9 O62605 A0A437BH48

KEGG

101737805 no KO assigned | (RefSeq) fibrohexamerin-like

GO

GO:0005198 GO:0005576 GO:0016020 GO:0005634 GO:0006355 GO:0030145 GO:0006412 GO:0016876 GO:0043039

Subcellular location

Secreted

SignalP

Position: 1 - 18, Likelihood: 0.999442

Length:

241

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02123

Exp number, first 60 AAs:

0.00327

Total prob of N-in:

0.01009

outside

1 - 241

Pi

290.424774

Theta

185.816286

Tajima's D

1.653556

CLR

0.22489

CSRT

0.818959052047398

Interpretation

Uncertain

Source	Sequence	Identity	Evalue
25860555	EGGICTVAEDCPSDIR	100.00	0.008
27102218	KYFSSNSK	100.00	0.008

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics

Multiple alignment of Orthologues

Gene Tree