Gene

KWMTBOMO08316  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009259

Annotation

PREDICTED:_uncharacterized_protein_LOC105842476_[Bombyx_mori]

Location

Bomo_Chr14(+):5257675-5263088      View in EpiBrowser

Full name

Fibrohexamerin      

Alternative Name

25 kDa silk glycoprotein
p25

Location in the cell

Nuclear   Reliability : 1.105 PlasmaMembrane   Reliability : 1.15

CDS

ATGTGGTTTGAACAGTGCCTGTGCCTTTCAGTTTTGGGTTTGATCGCTTCTGCTGTTGCTTTTGGAGAGAACTTGGATCCGGCCGATGACCCAAAAAACATCAAAAGACCCTGTCCGAACTTCGACTTGAACTGCATTCGTGAATATTTCTCAAGAAATTCTCAATGTCAATTAGTAATGGGATCTGTACCAGATCCACTACCTTTAAATTACTACAGAGTAGATATACCGAATAGTAATTTAACCGTAGAATATCATGATGTTAAAACCAGAGGCTTCGATACTATTAAAATCATTGAGTTTTACATTAACAGCAAAACCGAAAAACTAGTATTAGCAGCAGAAGTGCAGTCCTTAAAATTGGCTTCGCCGAAAACAATTTTCAAATACAATAGGAAAGCCAAAGAGCCAATTGTAAGAAGTGACGCATTGGAAGTTGACTATGGAACTCTAACGTTTACCGCTGTATTTCCGAGCATTAGCGACCTACAGTTGAGCAATGCTGAAGTTTTTAGTTACGTCCATGAAATCAATCCAAAATTCATTTTAGGACCTCTTCTATCGTTTAGTCTAGATTCTGAGACACAAAGTCAGTTAGGCAAGCTGCTGAACAACATCGCGGTTAGTCTTCAAGAAGTATTTGAAGCGCAAGGAACTATTTTAATGACCAGTTATATACAGTACGATATCTGTGACTTTGGATTAGAGTTAGCGTCTTAA

Protein

MWFEQCLCLSVLGLIASAVAFGENLDPADDPKNIKRPCPNFDLNCIREYFSRNSQCQLVMGSVPDPLPLNYYRVDIPNSNLTVEYHDVKTRGFDTIKIIEFYINSKTEKLVLAAEVQSLKLASPKTIFKYNRKAKEPIVRSDALEVDYGTLTFTAVFPSISDLQLSNAEVFSYVHEINPKFILGPLLSFSLDSETQSQLGKLLNNIAVSLQEVFEAQGTILMTSYIQYDICDFGLELAS

Subunit

Silk fibroin elementary unit consists in a disulfide-linked heavy and light chain and a p25 glycoprotein in molar ratios of 6:6:1. This results in a complex of approximately 2.3 MDa.

Miscellaneous

It is unclear whether the N-terminal residue of the mature protein is Ala-17 or Gly-18.

Keywords

Complete proteome   Direct protein sequencing   Disulfide bond   Glycoprotein   Reference proteome   Secreted   Signal   Silk protein  

Feature

chain  Fibrohexamerin

Uniprot

H9JIA9   H9JIB1   A0A2W1BYP1   A0A0M3VH85   A0A0M4UR85   A0A2A4J112   + More
A0A0M4U1I3   A0A0L7L2A8   A0A2W1BSA2   A0A0L7L1X1   A0A2W1BS92   Q9BLL8   Q9BLL6   P04148   H9IVR6   A0A437BH48   A0A212EPK5   A0A1V0PND8   O62605   Q14UU6   A0A2A4JH46   D0EWD9   A0A2H1VQJ6   Q9BLL4   A0A194PTN4   A0A0N1IP14  

Pubmed

19121390    28756777    26227816    11267905    3748814    14614147    + More
15141943    2987837    10986287    22118469    9520260    9583947    7715595    16755355    20171223    26354079   

EMBL

BABH01022225    BABH01022228    KZ149916    PZC77940.1    LC001864    BAS31052.1    + More
LC001863    BAS31051.1    NWSH01003760    PCG65847.1    LC001865    BAS31053.1    JTDY01003497    KOB69466.1    PZC77938.1    KOB69467.1    PZC77939.1    AB001821    BAB39500.1    AB001823    BAB39502.1    X04226    BP122961    BP126317    BP177743    BAAB01057839    BABH01038094    BABH01038095    RSAL01000058    RVE49720.1    AGBW02013452    OWR43406.1    KY792994    ARE31005.1    AF009827    AF009677    AB195976    BAE97692.1    NWSH01001474    PCG71139.1    GQ901976    ACX50393.1    ODYU01003822    SOQ43056.1    AB001825    BAB39504.1    KQ459593    KPI96677.1    KQ460854    KPJ11963.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000283053    UP000007151    UP000053268    + More
UP000053240   

PRIDE

H9JIA9    H9JIB1    Q9BLL8    Q9BLL6    P04148    H9IVR6    + More
Q9BLL4   

Pfam

PF07294   Fibroin_P25

Interpro

IPR009911   Fibroin_P25        + More
IPR038606   To_sf       
IPR016024   ARM-type_fold       
IPR011989   ARM-like       

SUPFAM

SSF48371   SSF48371       

Gene 3D

3.15.10.30     1.25.10.10    

ProteinModelPortal

H9JIA9   H9JIB1   A0A2W1BYP1   A0A0M3VH85   A0A0M4UR85   A0A2A4J112   + More
A0A0M4U1I3   A0A0L7L2A8   A0A2W1BSA2   A0A0L7L1X1   A0A2W1BS92   Q9BLL8   Q9BLL6   P04148   H9IVR6   A0A437BH48   A0A212EPK5   A0A1V0PND8   O62605   Q14UU6   A0A2A4JH46   D0EWD9   A0A2H1VQJ6   Q9BLL4   A0A194PTN4   A0A0N1IP14  

KEGG

101737673    no KO assigned | (RefSeq) fibrohexamerin-like

GO

GO:0005198   GO:0005576   GO:0016020   GO:0005634   GO:0006355   GO:0030145   GO:0006412   GO:0016876   GO:0043039  

Subcellular location

Secreted  

SignalP

Position:   1 - 22,         Likelihood:  0.988277

 

 

Length:

239

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.11716

Exp number, first 60 AAs:

1.11439

Total prob of N-in:

0.07779

outside

1  -  239

 

 

Pi

197.104965

Theta

162.777103

Tajima's D

1.006778

CLR

0.40844

CSRT

0.658917054147293

Interpretation

Uncertain