Gene

KWMTBOMO08296

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr14(-):4576842-4581724      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.198

CDS

ATGGAGTCCACGATCGATCTGTTCGCGGAATTCCTCCGTCTGAGGTACCCGACATTATCGGCCGAATTTTTAGAATTTAAGGCCAATCACGCCGCGAACTCAGAAGCGGTCTCCGTCGCGCCCGCCGCTCCCGTGTCCCCAATACTCGCGAGCAAAGCTCCCGCGTCGATCGCTGCGGTCTCGGTTCCAGCCCTGCGCTCATCCGCAGCACACGTCGCGTCCACGCGTTCATCCGCGGCCTCCATCGCGCCCGCGCCGTCCTCTGCCCCCGAGCGATTGTCCGTGGCCTCCGTCGCGACCGTCAACCCCGCGCCCTCTAAAACGCCCGCCTGCGGGTCGCCCGCGCCCTCCTCTTCATCCGACTCGGAGTCGGACATGGAGGTCGATCTTTCCCCCGCCCCCTCGACTGATGGATTCACAGTAGTCCAAAAAGGTAAGAGGCGCGCTGCGGAAGCCCGAGCTCCCGCGGCCGCCAAAGAGGAGCGCGAACTTCGTGCCGTCATACGTGGCATCCCTAAAGAGTTGGATGCCGAACTCGTCAAGGCCGACCTTCTGGAACAAGGCCTACCAGTAAATTCAGTGCACCGCATGCACACCGGCCGCGGTAGGGAGCCATATAATATGGTTCTAGTCGCCCTCCAGCCTACCCCCGAGGGTGACGCCATCCGCGCCGCCTCCACTGCACAGCACTTCATCGCCGTTGTGCAAGAATACGCCGACGTATACGCGTCGTTAAATACTGATATCGAGGCGCTGCTCAGCATGGGAAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAATTCTCACACCACAACCCCTAATGGCAGGCGGCTCGACGCGCTAGTTGATGATCTCGCCTTCGATATCATCGCTCCGCTAACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAGCTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCGTCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAGCCCGGACTCTACCCCGTCTCTTCAGGATACCGCTGAAGCCATAGACATCCTAACGTCACACATTACCTCGACATTAGATAGGTCATCGAAGCAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCGAATTGCCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCTTCGATCCGCGCCTACGATAGGTATCCTACCATGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGATGTAAAGTCTCGCATCGCCGAAATCCGAGATGCTAGGTGGTCTGATTTCTTAGAAGGACTCGCGCCCTCTCAAAGGTCTTACTACCGTTTAGCTCGTACTCTCAAATCGGATACGGTTGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGTCGACTCGCGGCGTTTGATGATGACGAAAAAGCAGAGCCGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCATTCAATCCGCGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTCGGATGCGTTACCACCCGTCACCCCAATGGAAGTTAAAGACCTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCTAACCGCGTTATTAAACTTCTACCCATCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCAGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGTTACCGCCCGATTAGCCTCCTCATGTCTCTGGGCAAACTGTATGAGCGTTTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCAAAGGGCATTCTCATCGATGAACAATTCGGATTCCGTGCAAATCACTCATGCGTACAACAGGTGCACCGCCTCACGGAGCACATTCTTGTAGGACTTAACCGACCAAAACCGATCTATACGGGAGCCCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAACGGTTTGATTTTCAAACTTTTCAACATGGGCGTACCGGATAGTCTCGTGCTCATCATACGAGACTTCTTGTCTAACCGCTCTTTTCGATATCGAGTAGAGGGAACCCGCTCCTCCCCGCGACCACTCACGGCTGGAGTCCCGCAAGGCTCCGTTCTCTCTCCGCTCCTATTTAGTTTATTTATTAACGATATTCCCCGGTCGCCGCCGACTCAGCTAGCCTTATTCGCTGACGACACAACCGTTTACTACTCAAGTAGAAACAAGTCCCTAATCGCGAGTAAGCTCCAGAGTGCAGCGTTAACCCTCGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGCACAGCAGTGTTATTTCAAAGGGGAAACTCACCGCTTATTTCCTCCCGCATTAGGAGGAGAAATATCACACCCCCGATCACCCTCTTCGGCCAACCTATACCCTGGGCTAGGAAGGTCAAGTACCTGGGAGTCACCCTGGATGCATCCATGACATTCCGCCCGCATATAAAAACAGTCCGCGATCGTGCCGCATTTATTCTCGGCAGACTCTATCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCCGTCGGGGCTCCGTGGTTCGTGAGGAACGTCGACCTACACGACGACCTGGGCCTCGAATCGATCCGCAAACACATGAAGTCAGTGTCGGAACGTTACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCTGCCGCTGACTATTCCCCGAATCCTGATCACGCAGGAGCAAGTCACCGTCGTCGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACTCTTGCATTAGATACCTTCAGCTCTAACACTAGGAGCAGGCTGAGGAACCCCGGTAACCGTACGCGTCGAACTCGACAAAGAGGTCGACGTGCAGCCTAA

Protein

MESTIDLFAEFLRLRYPTLSAEFLEFKANHAANSEAVSVAPAAPVSPILASKAPASIAAVSVPALRSSAAHVASTRSSAASIAPAPSSAPERLSVASVATVNPAPSKTPACGSPAPSSSSDSESDMEVDLSPAPSTDGFTVVQKGKRRAAEARAPAAAKEERELRAVIRGIPKELDAELVKADLLEQGLPVNSVHRMHTGRGREPYNMVLVALQPTPEGDAIRAASTAQHFIAVVQEYADVYASLNTDIEALLSMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIIAPLTPTHYPLNIAHRPDILDIALLKNVALRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGVSLAESDPPSLPFSPDSTPSLQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFELPDDIRELLRAKNASIRAYDRYPTMENRIRMRALQRDVKSRIAEIRDARWSDFLEGLAPSQRSYYRLARTLKSDTVVTMPPLVGPSGRLAAFDDDEKAEPLADTLQTQCTPSIQSADPVHVELVDSEVERRASLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGISNRVIKLLPIQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRANHSCVQQVHRLTEHILVGLNRPKPIYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFINDIPRSPPTQLALFADDTTVYYSSRNKSLIASKLQSAALTLGQWFRKWRIDINPAKSTAVLFQRGNSPLISSRIRRRNITPPITLFGQPIPWARKVKYLGVTLDASMTFRPHIKTVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKHMKSVSERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITLALDTFSSNTRSRLRNPGNRTRRTRQRGRRAA

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139WA11   V5GNJ2   A0A139W8G9   V5GNF3   X1WLB2   A0A023EYS8   A0A2S2PPK8   A0A2S2QEE0   A0A224XF24   J9LC21   X1WZH0   X1WNI2   A0A023EZE6   A0A224XB44   K7IN67   A0A2J7PQB5   A0A1Y1LKN6   J9M522   A0A2J7R7D0   A0A2M4CV52   A0A2S2Q383   A0A224X6Q4   J9LFC9   A0A2M4CV42   J9KPF1   A0A0A9YJ00   A0A2J7QR37   A0A2S2NGV8   A0A2J7PU96   A0A2J7PBY3   A0A224XI99   A0A2J7QY69   Q07995   A0A2M4BEF4   A0A1Y1KFR3   A0A3N5Z7I3   A0A2M4BD83   A0A2M4BEZ9   A0A0A9YU04   A0A224X6S1   A0A224X6U5   A0A2M4BDA5   A0A2M4BD66   A0A2M4BD62   A0A2S2N814   A0A2M4BD67   A0A2J7PVX3   A0A2M4BDV6   Q95SX7   A0A224X6T4   A0A2J7PDM0   A0A023F069   A0A2A4K918   A0A224XIB0   A0A2S2NH02   A0A224XJI0   A0A2S2R9D4   A0A1B6EGD8   A0A2J7Q6J2   A0A2J7QB68   A0A142LX49   A0A224X746   A0A2S2N6Q7   A0A087UGF5   Q8T9X4   Q8I7P8   A0A069DZL8   A0A2H8TF37   A0A224X6W2   J9KSK5   A0A2J7QFL0   A0A2J7R2E1   A0A352X8G4   A0A2J7RKP3   A0A2S2P6S3  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    20075255    25401762    8387152    30086797    7753626    12537569    25527032    26334808    30148503   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    KQ973342    KXZ75569.1    GALX01005359    JAB63107.1    ABLF02042518    ABLF02057746    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    GGMS01006359    MBY75562.1    GFTR01008038    JAW08388.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    ABLF02034467    ABLF02008153    ABLF02008462    ABLF02008464    GBBI01004571    JAC14141.1    GFTR01008262    JAW08164.1    NEVH01022639    PNF18527.1    GEZM01053022    JAV74219.1    ABLF02024246    NEVH01006736    PNF36716.1    GGFL01004957    MBW69135.1    GGMS01002992    MBY72195.1    GFTR01008279    JAW08147.1    ABLF02023911    GGFL01005012    MBW69190.1    ABLF02041767    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    NEVH01011985    PNF31054.1    GGMR01003407    MBY16026.1    NEVH01021205    PNF19912.1    NEVH01027074    PNF13841.1    GFTR01008256    JAW08170.1    NEVH01009134    PNF33528.1    S59870    AAB26437.2    GGFJ01002256    MBW51397.1    GEZM01084969    JAV60363.1    RPOV01000134    RPJ78669.1    GGFJ01001822    MBW50963.1    GGFJ01002257    MBW51398.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GFTR01008271    JAW08155.1    GFTR01008251    JAW08175.1    GGFJ01001842    MBW50983.1    GGFJ01001844    MBW50985.1    GGFJ01001843    MBW50984.1    GGMR01000676    MBY13295.1    GGFJ01001858    MBW50999.1    NEVH01020940    PNF20481.1    GGFJ01001857    MBW50998.1    AY060438    AAL25477.1    GFTR01008261    JAW08165.1    NEVH01026386    PNF14434.1    GBBI01003810    JAC14902.1    NWSH01000032    PCG80496.1    GFTR01008246    JAW08180.1    GGMR01003864    MBY16483.1    GFTR01008257    JAW08169.1    GGMS01017365    MBY86568.1    GEDC01000337    JAS36961.1    NEVH01017470    PNF24199.1    NEVH01016302    PNF25823.1    KU543685    AMS38375.1    GFTR01008151    JAW08275.1    GGMR01000226    MBY12845.1    KK119692    KFM76444.1    AF456125    AAL57609.1    AY180919    AAN87272.1    GBGD01000415    JAC88474.1    GFXV01000908    MBW12713.1    GFTR01008260    JAW08166.1    ABLF02014118    ABLF02014121    ABLF02054790    NEVH01014858    PNF27387.1    NEVH01007838    PNF34986.1    DNOY01000259    HBE18313.1    NEVH01002716    PNF41415.1    GGMR01012443    MBY25062.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000002358    UP000235965    UP000218220    + More
UP000054359   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    Q95SX7    Q8T9X4    Q8I7P8    + More

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139WA11   V5GNJ2   A0A139W8G9   V5GNF3   X1WLB2   A0A023EYS8   A0A2S2PPK8   A0A2S2QEE0   A0A224XF24   J9LC21   X1WZH0   X1WNI2   A0A023EZE6   A0A224XB44   K7IN67   A0A2J7PQB5   A0A1Y1LKN6   J9M522   A0A2J7R7D0   A0A2M4CV52   A0A2S2Q383   A0A224X6Q4   J9LFC9   A0A2M4CV42   J9KPF1   A0A0A9YJ00   A0A2J7QR37   A0A2S2NGV8   A0A2J7PU96   A0A2J7PBY3   A0A224XI99   A0A2J7QY69   Q07995   A0A2M4BEF4   A0A1Y1KFR3   A0A3N5Z7I3   A0A2M4BD83   A0A2M4BEZ9   A0A0A9YU04   A0A224X6S1   A0A224X6U5   A0A2M4BDA5   A0A2M4BD66   A0A2M4BD62   A0A2S2N814   A0A2M4BD67   A0A2J7PVX3   A0A2M4BDV6   Q95SX7   A0A224X6T4   A0A2J7PDM0   A0A023F069   A0A2A4K918   A0A224XIB0   A0A2S2NH02   A0A224XJI0   A0A2S2R9D4   A0A1B6EGD8   A0A2J7Q6J2   A0A2J7QB68   A0A142LX49   A0A224X746   A0A2S2N6Q7   A0A087UGF5   Q8T9X4   Q8I7P8   A0A069DZL8   A0A2H8TF37   A0A224X6W2   J9KSK5   A0A2J7QFL0   A0A2J7R2E1   A0A352X8G4   A0A2J7RKP3   A0A2S2P6S3  

PDB

6AR3     E-value=0.0250228,     Score=92

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1080

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.88307

Exp number, first 60 AAs:

0.00119

Total prob of N-in:

0.00040

outside

1  -  1080

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

142.285328

CSRT

0

Interpretation

Uncertain