Gene

KWMTBOMO08294  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009544

Annotation

integument_esterase_2_precursor_[Bombyx_mori]

Location

Bomo_Chr14(+):4515005-4528372      View in EpiBrowser

Full name

Carboxylic ester hydrolase      

Location in the cell

Extracellular   Reliability : 0.97

CDS

ATGTCCCGTACATTCGCACTTTTAATTAACTCAGTGTTATTGTTTGCTGCTTATGGACAATGCCATGAGGGTCATGGCCACCACCATCACGATCAGAACGTCGGACACCAGCACGACCGTCCTTCGCCAAAGGTAACGTCAGCATCCGGAGTATTTCTCGGTTCCTGGATGCAGACCCGTCGCGGAAGACATTTCCAAGGCTTCCGCGGTATCAGATACGCTGAAGCTCCCGTTGGAGATCTAAGATTCCAGGCCCCAAAACCAATACTCCAATATTCAGGAGAAGTGGACGCCAGCAAGGAAGGCCCGGCCTGTCCGCAACCAACTAATCCGAACTATTACAACAATGTAGACGAGGACTGCCTTCGACTAAATGTCTACACTCACGGAAGCTCAGGAGAACTTCGTCCAGTAGTGATATTTATCCATGCCGGTGGATTCTACGCTGCGTCCGGTCGTAGCGACATCGCCGGTCCGGACTATTTCCTGGATAAAGACATTGTGCTGGTCACAATCAACTATCGTTTATCTTCTCTTGGTTTCTTGAGTACGGGTGACGAGCTCGCTCCCGGGAACAATGGATACAAAGACCAAGTAATGGCCATGCGCTGGGTACAGAGGAACATCGCGTCATTCGGCGGCGACCCTAACCTGGTCACGATAGCTGGTTACAGCGCCGGTTCATTCAGCGTCATGCTTCATACTGTCTCTCCTATGTCTAAAGGTCTCTTCCATCGTGCGATATCAATGAGCGGCTCCCCGATTTCTCAAGTGGTGATCCCACATGATCAACGCCAATTAGCCGTGAGGCAGGCCGAGTTACTCGACTGCCCTACCAACAGCTCGCGAGCTATTATTGATTGCCTCAAGACTAAGCCTTGGAGGGATATCGGGAATTCTCTGCGTGGATTCTTCGAATTCGCTTACGACCCGGTCCTGATCTGGGTTCCACTTGTAGAGAAGGATTACGGACAAGAAAGGTTCCTCGTCAAGCAGCCTTTGGACTCGATACGTCAAAGAGAAATACATTCTGTTCCGTACATCATTAGTCAAACACAGGACGAGTTCTTTTGGAAAGCTTTGAATATCCTCGCTAACCAGACTCTGACAGACACAATGAATAACGAATGGGAACGGATAGCTCCAATTTCCTTCTACCTTCCTGCGAGTACATCACGCCAAGCTTCCAATAAACTGAAGCAAGCCTACCTTGGTGGGAAGAAATTGGTCAATGATACTGCCAGTGCTGATGGCCTAGGGAAGTTATATAATGACGCTATTATTGGGTTTGGGGTGCACAGATTGGTGAACCTCATGAGTCAATATTCATCCAAACCGGTCTATTACTACGAGTTTGCTTACATCGGAAACCACAGCCACTACGAAGATCCCGTCACCAAGAAACCTACTGGTGCAGCCCACCACGACGAGCTGATCTATTTGTTCAGTGTCAACGCTACCTTCCCGTTCATAGAAGCCTCTGACAGCCTCGACTCGAAGATGGTTGACAAAATGACTAGCATCTGGTACAACTTCCTTAAAAACGGAGATCCGAATCCCCGGGATAACAATCCTGAGTTATCAGGTCTGTCTTGGCCGGCTATGAAGCCCAACGACAGGAAATACCTTCGCATCGACAAGACTTTCTCGGTCCATGAAAACCTCTTCGAAGATAGGTTCAAGATCTGGGAAGAGCTGTACCCGATAACCAATTGA

Protein

MSRTFALLINSVLLFAAYGQCHEGHGHHHHDQNVGHQHDRPSPKVTSASGVFLGSWMQTRRGRHFQGFRGIRYAEAPVGDLRFQAPKPILQYSGEVDASKEGPACPQPTNPNYYNNVDEDCLRLNVYTHGSSGELRPVVIFIHAGGFYAASGRSDIAGPDYFLDKDIVLVTINYRLSSLGFLSTGDELAPGNNGYKDQVMAMRWVQRNIASFGGDPNLVTIAGYSAGSFSVMLHTVSPMSKGLFHRAISMSGSPISQVVIPHDQRQLAVRQAELLDCPTNSSRAIIDCLKTKPWRDIGNSLRGFFEFAYDPVLIWVPLVEKDYGQERFLVKQPLDSIRQREIHSVPYIISQTQDEFFWKALNILANQTLTDTMNNEWERIAPISFYLPASTSRQASNKLKQAYLGGKKLVNDTASADGLGKLYNDAIIGFGVHRLVNLMSQYSSKPVYYYEFAYIGNHSHYEDPVTKKPTGAAHHDELIYLFSVNATFPFIEASDSLDSKMVDKMTSIWYNFLKNGDPNPRDNNPELSGLSWPAMKPNDRKYLRIDKTFSVHENLFEDRFKIWEELYPITN

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Feature

chain  Carboxylic ester hydrolase

Uniprot

B2ZDZ0   H9JJ43   A0A076FT16   A0A0K0XRW3   A0A0B4RXV7   A0A2W1BGD8   + More
A0A2S0D926   D3GDM7   A0A1J0M181   A0A0C5BXG4   A0A2H1WGB8   A0A2H1VGL5   A0A2W1BDQ9   A0A0N1IIX7   I4DLI1   A0A0N0PEB7   A0A194QK91   A0A076FX71   A0A2A4K191   A0A2W1BKS7   A0A291P108   E5KG18   A0A291P0U7   A0A212F6F1   A0A3S2P4M1   A0A0K0XRX2   A0A0L7LEE9   A0A0F7QJW7   A0A2H1VH21   A0A1J0M1W5   A0A0C5C585   D3GDL6   A0A212EM26   Q86MC6   Q76LV8   A0A0K8TVB4   A0A0C5CGX5   A0A0N1IIX1   A0A1U9X1V2   H9JW98   B8YPE6   B0FGV8   A0A2H1V723   A0A2H1VEG4   A0A2H1WKG0   D5G3G0   A0A0Y0BNW5   A0A1U9X1V4   A0A2S0D932   A0A437AV85   A0A194QEI5   A0A1L8D6X6   A0A3S2TCS4   A0A2A4K1B6   A0A0K8TV90   A0A0C9QZ47   A0A0K1YW36   K7INH0   D6WVK5   A0A1Y1KWW8   J3JWT7   D6WNV1   K7IV21   A0A0K1YW45   A0A0A7EQ91   A0A0A7ENN7   A0A1Y1KPD4   A0A1Q3G524   A0A0L7RHV8   A0A0K1YW79   A0A1W6L1A2   A0A0A7EP09   A0A232FG81   A0A1B0BYB9   A0A1A9YLN6   K7INH1   K7INH2   A0A2M3YYC8   A0A1Y1LPN2   A0A232FF06   A0A2M3YYC3   Q16XU6   W5JNZ8   A0A034WHL8   A0A1W4WNW7   A0A125S6Q4   A0A1S4FKP8   A0A411G7G8   A0A2M4BIY1   A0A1I8M3D0   A0A182FLE8   A0A2M4A4R8   A0A2M4A4W3   A0A2M4A4R9   A0A2M4A574   A0A0K1YW83   T1PHJ3  

EC Number

3.1.1.-

Pubmed

19121390    24817326    26198868    28756777    26354079    22651552    + More
28986331    24753123    22118469    26227816    25803580    26017144    20005949    26778204    20075255    18362917    19820115    28004739    22516182    28648823    17510324    20920257    23761445    25348373    25315136   

EMBL

EU647213    ACD03181.1    BABH01040271    BABH01040272    KF960787    AII21989.1    + More
KP938881    AKS40362.1    KJ023203    AIY69031.1    KZ150111    PZC73331.1    KX015847    ARM65376.1    FJ652459    ACV60243.1    KU375434    APD13876.1    KP001148    AJN91193.1    ODYU01008145    SOQ51504.1    ODYU01002465    SOQ39989.1    PZC73332.1    KQ459670    KPJ20505.1    AK402149    BAM18771.1    KQ459866    KPJ19691.1    KQ459054    KPJ03876.1    KF960779    AII21981.1    NWSH01000325    PCG77440.1    PZC73330.1    MF687623    ATJ44549.1    HQ116561    ADR64702.1    MF687554    ATJ44480.1    AGBW02010035    OWR49316.1    RSAL01000471    RVE41610.1    KP938890    AKS40371.1    JTDY01001491    KOB73744.1    LC017763    BAR64777.1    ODYU01002498    SOQ40051.1    KU375428    APD13870.1    KP001150    AJN91195.1    FJ652448    ACV60232.1    AGBW02013941    OWR42542.1    AY091504    AAM14416.1    AB072256    BAC22502.1    GCVX01000024    JAI18206.1    KP001147    AJN91192.1    KPJ20489.1    KY021845    AQY62734.1    BABH01029396    BABH01029397    FJ556876    ACL83459.1    EU328352    ABY57298.1    ODYU01000992    SOQ36586.1    ODYU01002118    SOQ39209.1    ODYU01009159    SOQ53392.1    FJ997324    ADF43489.1    KU215368    AMB19662.1    KY021844    AQY62733.1    KX015858    ARM65387.1    RSAL01000382    RVE42048.1    KPJ03892.1    GEYN01000035    JAV02094.1    RSAL01000351    RVE42264.1    PCG77460.1    GCVX01000027    JAI18203.1    GBYB01009074    JAG78841.1    KP859351    AKZ17661.1    KQ971357    EFA08586.1    GEZM01075891    JAV63896.1    BT127705    AEE62667.1    KQ971343    EFA04389.1    AAZX01001198    KP859361    AKZ17671.1    KM220539    AIY68330.1    KM220537    AIY68328.1    GEZM01077562    GEZM01077561    JAV63272.1    GFDL01000152    JAV34893.1    KQ414590    KOC70368.1    KP859360    AKZ17670.1    KX609461    ARN17868.1    KM220541    AIY68332.1    NNAY01000280    OXU29530.1    JXJN01022584    GGFM01000505    MBW21256.1    GEZM01054549    JAV73566.1    NNAY01000334    OXU29133.1    GGFM01000522    MBW21273.1    CH477532    EAT39446.1    ADMH02000998    ETN64479.1    GAKP01005130    JAC53822.1    KT601146    AME15815.1    MH366017    QBB01826.1    GGFJ01003866    MBW53007.1    GGFK01002483    MBW35804.1    GGFK01002488    MBW35809.1    GGFK01002476    MBW35797.1    GGFK01002477    MBW35798.1    KP859365    AKZ17675.1    KA648292    AFP62921.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000218220    UP000007151    UP000283053    + More
UP000037510    UP000002358    UP000007266    UP000053825    UP000215335    UP000092460    UP000092443    UP000008820    UP000000673    UP000192223    UP000095301    UP000069272   

PRIDE

B2ZDZ0    H9JJ43    H9JW98    B0FGV8   

Pfam

PF00135   COesterase        + More
PF00405   Transferrin

Interpro

IPR002018   CarbesteraseB        + More
IPR019826   Carboxylesterase_B_AS       
IPR029058   AB_hydrolase       
IPR019819   Carboxylesterase_B_CS       
IPR018195   Transferrin_Fe_BS       
IPR001156   Transferrin-like_dom       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

B2ZDZ0   H9JJ43   A0A076FT16   A0A0K0XRW3   A0A0B4RXV7   A0A2W1BGD8   + More
A0A2S0D926   D3GDM7   A0A1J0M181   A0A0C5BXG4   A0A2H1WGB8   A0A2H1VGL5   A0A2W1BDQ9   A0A0N1IIX7   I4DLI1   A0A0N0PEB7   A0A194QK91   A0A076FX71   A0A2A4K191   A0A2W1BKS7   A0A291P108   E5KG18   A0A291P0U7   A0A212F6F1   A0A3S2P4M1   A0A0K0XRX2   A0A0L7LEE9   A0A0F7QJW7   A0A2H1VH21   A0A1J0M1W5   A0A0C5C585   D3GDL6   A0A212EM26   Q86MC6   Q76LV8   A0A0K8TVB4   A0A0C5CGX5   A0A0N1IIX1   A0A1U9X1V2   H9JW98   B8YPE6   B0FGV8   A0A2H1V723   A0A2H1VEG4   A0A2H1WKG0   D5G3G0   A0A0Y0BNW5   A0A1U9X1V4   A0A2S0D932   A0A437AV85   A0A194QEI5   A0A1L8D6X6   A0A3S2TCS4   A0A2A4K1B6   A0A0K8TV90   A0A0C9QZ47   A0A0K1YW36   K7INH0   D6WVK5   A0A1Y1KWW8   J3JWT7   D6WNV1   K7IV21   A0A0K1YW45   A0A0A7EQ91   A0A0A7ENN7   A0A1Y1KPD4   A0A1Q3G524   A0A0L7RHV8   A0A0K1YW79   A0A1W6L1A2   A0A0A7EP09   A0A232FG81   A0A1B0BYB9   A0A1A9YLN6   K7INH1   K7INH2   A0A2M3YYC8   A0A1Y1LPN2   A0A232FF06   A0A2M3YYC3   Q16XU6   W5JNZ8   A0A034WHL8   A0A1W4WNW7   A0A125S6Q4   A0A1S4FKP8   A0A411G7G8   A0A2M4BIY1   A0A1I8M3D0   A0A182FLE8   A0A2M4A4R8   A0A2M4A4W3   A0A2M4A4R9   A0A2M4A574   A0A0K1YW83   T1PHJ3  

PDB

5TYM     E-value=3.59897e-54,     Score=537

KEGG

692374    no KO assigned | (RefSeq) ie2, Bmie2, Care-12, Esr-lp; integument esterase 2

GO

GO:0016787   GO:0005615   GO:0052689   GO:0005576  

SignalP

Position:   1 - 21,         Likelihood:  0.969207

 

 

Length:

571

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.24817

Exp number, first 60 AAs:

0.10419

Total prob of N-in:

0.01183

outside

1  -  571

 

 

Pi

352.306029

Theta

178.962816

Tajima's D

2.835081

CLR

0.291051

CSRT

0.970501474926254

Interpretation

Uncertain