Gene

KWMTBOMO08261

Pre Gene Modal

BGIBMGA009523

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_probable_cytochrome_P450_49a1_[Papilio_polytes]

Location

Bomo_Chr14(+):2946019-2958280      View in EpiBrowser

Full name

Probable cytochrome P450 49a1      

Alternative Name

CYPXLIXA1

Location in the cell

Mitochondrial   Reliability : 1.42

CDS

ATGCTTTCCACGTGTCCCGTCCACATCCAGCGAGCCAGGTCCACTCACGTCGTGGACGCTACAGCCTTTGAAGTATCGTCTCCTGTCAAACCCTGGGAAGATGTACCAGGTCCAAAGCCACTGCCCTTACTTGGAAACACTTGGAGGTTCACTCCTTATATCGGGAGCTACTCAGTCGAACACATTGACAGGATATGCGTATCTCTACGCGCGAAATACGGGAAGTGTGTCAAGATGGCAGGTCTATTGGGGCGACCGGATATGCTGTTCGTATTTGATGCTAACGAAGTCGAGAGGGTGTTTAGAGGAGAGGATGCCGCACCCCATCGTCCTTCAATGCCTTCATTGAATTACTACAAGCACACGCTCCGAAAAGATTTCTTTAGCGCCGAGGAAAACTGCGCTGGAGTTATTGCTGTGCATGGAGACTCGTGGTCCGCGTTCAGGACGAAGGTGTCGAGAGTGGCGCTAAGTGCGGGCGCGGCTGCCCAGTACACGGCGCCAGTGGCTGAAGTGGCTGATTGTTTTGTGGAAAGGTTCGTGTGA

Protein

MLSTCPVHIQRARSTHVVDATAFEVSSPVKPWEDVPGPKPLPLLGNTWRFTPYIGSYSVEHIDRICVSLRAKYGKCVKMAGLLGRPDMLFVFDANEVERVFRGEDAAPHRPSMPSLNYYKHTLRKDFFSAEENCAGVIAVHGDSWSAFRTKVSRVALSAGAAAQYTAPVAEVADCFVERFV

Description

May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.

Cofactor

heme

Similarity

Belongs to the cytochrome P450 family.

Keywords

Alternative splicing   Complete proteome   Endoplasmic reticulum   Heme   Iron   Membrane   Metal-binding   Microsome   Monooxygenase   Oxidoreductase   Reference proteome  

Feature

chain  Probable cytochrome P450 49a1
splice variant  In isoform C.

Uniprot

L0N5M4   A0A248QEZ9   A0A2A4K848   A0A2W1C0B2   A0A194Q424   A0A0N0PCY1   + More
A0A1V0D9E8   A0A212FL05   A0A3S2NTQ9   A0A1B6CMB7   A0A0M4H594   A0A2J7PYJ2   A0A2J7PYK4   A0A2J7PYJ0   A0A2J7PYM6   A0A2J7PYJ4   A0A067RSD6   D2A103   E0W2B1   E2AFK1   A0A0K8T711   A0A154PR32   A0A0L7R6B8   A0A2A3EML1   A0A026WVH3   R9UDY8   A0A088A457   A0A2S2P4U0   A0A0M9A7Y8   A0A0A9XQI3   A0A146M9Z8   A0A232F204   A0A146LD79   J9JRR2   K7J2R1   A0A1B6GSW2   A0A2P8Y3Y6   T1IDL2   A0A2D1GSD3   A0A2H8TLX1   W8B2Y4   N6TPR6   A0A067R674   A0A0K0LB65   A0A034VFW3   A0A336JXF2   A0A2J7PDU4   A0A1Q1NL03   A0A1J1J2W8   R9UB41   B4J7I9   A0A0M4HGU6   B4N662   A0A2S2QSX9   E0VDR0   A0A1W4VCA1   B4QIE0   B4KN43   B4NXN7   W8BEW4   W8B9Y6   B4HMQ3   A0A0R1DMZ7   A0A0K0LB64   A0A0M4ETM1   B3N6D8   A0A0B4K7M1   Q9V5L3   A0A125S6N7   D6WQ58   B3MI40   A0A2J7PYZ6   Q28XI1   B4GG60   A0A182HWH4   A0A182XML5   A0A182VDU1   A0A182UA43   A0A182L361   Q7PNM9   B4LKE7   Q16Y74   A0A182PLU9   U4U7G1   A0A3B0JN88   I1VJ31   A0A3B0JFL4   A0A0K8U800   A0A182J2S6   A0A1A9ZGA2   B0VZB4   A0A1Q3FMD9   A0A1W4XAH4   A0A2M4BKS7   W5J440  

EC Number

1.14.-.-

Pubmed

28881445    28756777    26354079    22118469    26319543    24845553    + More
18362917    19820115    20566863    20798317    24508170    30249741    25401762    26823975    28648823    20075255    29403074    24495485    23537049    25348373    28092127    17994087    22936249    18057021    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    15632085    20966253    12364791    14747013    17210077    17510324    22516182    20920257    23761445   

EMBL

AK343221    BAM73903.1    KX443475    ASO98050.1    NWSH01000071    PCG79963.1    + More
KZ149927    PZC77503.1    KQ459585    KPI98160.1    KQ460426    KPJ14777.1    KY212061    ARA91625.1    AGBW02007925    OWR54417.1    RSAL01000206    RVE44347.1    GEDC01022689    JAS14609.1    KR012815    ALD15890.1    NEVH01020348    PNF21413.1    PNF21416.1    PNF21411.1    PNF21412.1    PNF21417.1    KK852446    KDR23725.1    KQ971338    EFA02807.1    DS235875    EEB19767.1    GL439118    EFN67752.1    GBRD01004493    JAG61328.1    KQ435066    KZC14341.1    KQ414648    KOC66321.1    KZ288219    PBC32281.1    KK107085    QOIP01000008    EZA60040.1    RLU19440.1    JX462989    AGN52782.1    GGMR01011816    MBY24435.1    KQ435728    KOX77763.1    GBHO01021400    JAG22204.1    GDHC01002056    JAQ16573.1    NNAY01001258    OXU24592.1    GDHC01013597    JAQ05032.1    ABLF02025275    ABLF02025279    ABLF02046672    GECZ01004263    JAS65506.1    PYGN01000954    PSN38977.1    ACPB03012792    MF471397    ATN96003.1    GFXV01002483    MBW14288.1    GAMC01011085    JAB95470.1    APGK01059446    KB741293    ENN70281.1    KK852927    KDR13690.1    KM216993    AIW79956.1    GAKP01017945    JAC41007.1    UFQS01000004    UFQT01000004    SSW96881.1    SSX17268.1    NEVH01026142    PNF14497.1    KX660724    AQM57063.1    CVRI01000067    CRL06719.1    JX462971    AGN52764.1    CH916367    EDW01113.1    KR012817    ALD15892.1    CH964154    EDW79851.2    GGMS01011631    MBY80834.1    DS235083    EEB11516.1    CM000362    CM002911    EDX06500.1    KMY92793.1    CH933808    EDW08870.1    KRG04326.1    KRG04327.1    CM000157    EDW89662.1    KRJ98649.1    GAMC01011087    JAB95468.1    GAMC01011083    JAB95472.1    CH480816    EDW47265.1    KRJ98650.1    KM216992    AIW79955.1    CP012524    ALC40607.1    CH954177    EDV58107.1    KQS70245.1    AE013599    AFH08010.1    AY075453    AY102688    BT056244    KT601129    AME15798.1    KQ971354    EFA07521.1    CH902619    EDV38050.1    KPU77234.1    NEVH01020341    PNF21558.1    CM000071    EAL26335.1    CH479183    EDW35480.1    APCN01001491    AAAB01008960    EAA11902.5    CH940648    EDW61738.1    CH477523    EAT39564.1    KB632046    ERL88288.1    OUUW01000001    SPP74111.1    JQ855652    AFI45015.1    SPP74110.1    GDHF01029542    JAI22772.1    DS231813    EDS25689.1    GFDL01006328    JAV28717.1    GGFJ01004535    MBW53676.1    ADMH02002165    ETN58108.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000007151    UP000283053    UP000235965    + More
UP000027135    UP000007266    UP000009046    UP000000311    UP000076502    UP000053825    UP000242457    UP000053097    UP000279307    UP000005203    UP000053105    UP000215335    UP000007819    UP000002358    UP000245037    UP000015103    UP000019118    UP000183832    UP000001070    UP000007798    UP000192221    UP000000304    UP000009192    UP000002282    UP000001292    UP000092553    UP000008711    UP000000803    UP000007801    UP000001819    UP000008744    UP000075840    UP000076407    UP000075903    UP000075902    UP000075882    UP000007062    UP000008792    UP000008820    UP000075885    UP000030742    UP000268350    UP000075880    UP000092445    UP000002320    UP000192223    UP000000673   

PRIDE

L0N5M4    Q9V5L3   

Pfam

PF00067   p450

Interpro

IPR036396   Cyt_P450_sf        + More
IPR001128   Cyt_P450       
IPR017972   Cyt_P450_CS       
IPR002401   Cyt_P450_E_grp-I       
IPR002403   Cyt_P450_E_grp-IV       
IPR000253   FHA_dom       

SUPFAM

SSF48264   SSF48264       

Gene 3D

1.10.630.10    

ProteinModelPortal

L0N5M4   A0A248QEZ9   A0A2A4K848   A0A2W1C0B2   A0A194Q424   A0A0N0PCY1   + More
A0A1V0D9E8   A0A212FL05   A0A3S2NTQ9   A0A1B6CMB7   A0A0M4H594   A0A2J7PYJ2   A0A2J7PYK4   A0A2J7PYJ0   A0A2J7PYM6   A0A2J7PYJ4   A0A067RSD6   D2A103   E0W2B1   E2AFK1   A0A0K8T711   A0A154PR32   A0A0L7R6B8   A0A2A3EML1   A0A026WVH3   R9UDY8   A0A088A457   A0A2S2P4U0   A0A0M9A7Y8   A0A0A9XQI3   A0A146M9Z8   A0A232F204   A0A146LD79   J9JRR2   K7J2R1   A0A1B6GSW2   A0A2P8Y3Y6   T1IDL2   A0A2D1GSD3   A0A2H8TLX1   W8B2Y4   N6TPR6   A0A067R674   A0A0K0LB65   A0A034VFW3   A0A336JXF2   A0A2J7PDU4   A0A1Q1NL03   A0A1J1J2W8   R9UB41   B4J7I9   A0A0M4HGU6   B4N662   A0A2S2QSX9   E0VDR0   A0A1W4VCA1   B4QIE0   B4KN43   B4NXN7   W8BEW4   W8B9Y6   B4HMQ3   A0A0R1DMZ7   A0A0K0LB64   A0A0M4ETM1   B3N6D8   A0A0B4K7M1   Q9V5L3   A0A125S6N7   D6WQ58   B3MI40   A0A2J7PYZ6   Q28XI1   B4GG60   A0A182HWH4   A0A182XML5   A0A182VDU1   A0A182UA43   A0A182L361   Q7PNM9   B4LKE7   Q16Y74   A0A182PLU9   U4U7G1   A0A3B0JN88   I1VJ31   A0A3B0JFL4   A0A0K8U800   A0A182J2S6   A0A1A9ZGA2   B0VZB4   A0A1Q3FMD9   A0A1W4XAH4   A0A2M4BKS7   W5J440  

PDB

3K9Y     E-value=0.00581268,     Score=89

KEGG

101737184    K17960 cytochrome P450 family 49 subfamily A | (RefSeq) CYP49A1; probable cytochrome P450 49a1-like

GO

GO:0004497   GO:0020037   GO:0016705   GO:0005506   GO:0046872   GO:0008386   GO:0005789   GO:0003917   GO:0016887   GO:0005634   GO:0030145   GO:0006412   GO:0016876   GO:0043039   GO:0055114  

Subcellular location

Endoplasmic reticulum membrane  
Microsome membrane  

Length:

181

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01753

Exp number, first 60 AAs:

0.00068

Total prob of N-in:

0.07890

outside

1  -  181

 

 

Pi

220.742342

Theta

164.86583

Tajima's D

1.241673

CLR

0.392245

CSRT

0.720013999300035

Interpretation

Uncertain