Gene

KWMTBOMO08248

Pre Gene Modal

BGIBMGA009518

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_alpha-N-acetylgalactosaminidase-like_[Bombyx_mori]

Location

Bomo_Chr14(+):2716179-2794364      View in EpiBrowser

Full name

Alpha-galactosidase      

Location in the cell

Extracellular   Reliability : 1.062 Lysosomal   Reliability : 1.663 PlasmaMembrane   Reliability : 1.015

CDS

ATGGCTTCGTGGAAGTTTATCGCTGTGTCGACGGTTTGTTTGTTGGTGTTTCTGTCGGGTAACATCTCGGGACTGGACAATGGCTTGGTGCTGACGCCGCCCATGGGCTGGCTGGCCTGGGAACGGTTTAGGTGTAACACCGATTGCAAGAATGACCCTGAAAATTGTATCAGCGATCGTCTATTCCGTACCATGACCGATATCTTAGTGACCGAAGGGTATACCGCGGCTGGATATGAGTACATCAACGTGGACGACTGCTGGCTGGAGCGGGAGAGGGACGAGAGAGGTAGACTAGTGCCGGACAGAGAACGGTTCCCTTACGGAATGAAGAGCTTAGCCGATTATGTACACAGCAAGGGTCTGAAATTCGGTATTTACGAGGACTACGGTAATTTCACTTGCGCTGGCTACCCCGGAGTCGTCGGCCATCTTTCCGGAGATGCGACAACCTTCGCCTCATGGGGCGTCGACTACGTGAAGCTGGACGGGTGCTACGCCCTGCCAACGGACATGGATTACGGCTACCCTGAGTTCGGGAGACAGCTCAATCTTACTGGTCGTCAGATGGTGTACTCCTGTAGTTGGCCCGTCTATCAGATCTACGCTGGTCTACAGCCAAATTTTTCGTCAATAATCGAGCACTGCAATCTGTGGCGTAACTTCGACGACATCCAGGACTCGTGGGCCTCCGTCGAGTCTATCATAGACTACTATGGAAACCACCAAGACGTCATCGTGCCCAACGCTGGGCCGGGACACTGGAACGACCCCGACATGTTGATCGTCGGCAACTTTGGACTATCGTATGAGCAGAGCAAGACGCAGTTCGCACTATGGGCGATCCTGGCCGCGCCGCTGCTGATGAGCGTCGACCTGCGCACCATCAGGCCGGAGTACAAGGCCATTCTGCAGAACAGGAAGATCATCGAGGTCGACCAGGACCCCCTCGGCATACAAGGCAGGAGGATCTACAAGCACCGCGGCATCGAAATCTGGTCCCGCCCCATCCTGCCCATCCAGCAGGGACAGTTCTACTCGTACGCCGTGGCCTTCGTCAACAGGAGGACAGACGGGACTCCTTCCGACGTCGCCGTCACGCTGAGGGAGCTGGGGCTCAGCAACCCCACCGGCTACAGGGTCGAGGACCTGTACGAGGACGTGGATTACGGCGTGCTGTCGCCGCAGACGAAGATCAAGGTCAAGGTCAACCCCTCAGGTGTGGTGATTTTGAGGGCAGACGCGCAACCGGGCTACGCTTTCAACGCGATAACGACGCGGACTCCGTACACGCCACTCAACGACGTGTTCCGACTGACCAAGAAATAG

Protein

MASWKFIAVSTVCLLVFLSGNISGLDNGLVLTPPMGWLAWERFRCNTDCKNDPENCISDRLFRTMTDILVTEGYTAAGYEYINVDDCWLERERDERGRLVPDRERFPYGMKSLADYVHSKGLKFGIYEDYGNFTCAGYPGVVGHLSGDATTFASWGVDYVKLDGCYALPTDMDYGYPEFGRQLNLTGRQMVYSCSWPVYQIYAGLQPNFSSIIEHCNLWRNFDDIQDSWASVESIIDYYGNHQDVIVPNAGPGHWNDPDMLIVGNFGLSYEQSKTQFALWAILAAPLLMSVDLRTIRPEYKAILQNRKIIEVDQDPLGIQGRRIYKHRGIEIWSRPILPIQQGQFYSYAVAFVNRRTDGTPSDVAVTLRELGLSNPTGYRVEDLYEDVDYGVLSPQTKIKVKVNPSGVVILRADAQPGYAFNAITTRTPYTPLNDVFRLTKK

Subunit

Homodimer.

Similarity

Belongs to the glycosyl hydrolase 27 family.

Feature

chain  Alpha-galactosidase

Uniprot

A0A437BPU5   A0A2W1BQY8   A0A2A4JJP4   S4NSM8   I4DIL5   A0A0N1PES9   + More
E2B637   F4WJD6   A0A026WYH3   A0A151J0R5   D1ZZP5   J3JUA1   K7J2S2   A0A1Y1M843   A0A232EJJ6   A0A0J7KXZ7   U4UPP5   E2A7Y1   A0A1J1IRP1   Q17A03   A0A1B6CLQ8   A0A182Q255   A0A2A3EAC4   A0A1Q3G433   A0A195CCG6   A0A1Q3G451   A0A1S4H2E7   A0A182ICP7   A0A151WST7   A0A084VNI9   A0A1L8DR08   A0A182MV14   A0A195BWB5   A0A195FQA7   A0A1L8DQP1   A0A182VNL1   A0A182IPD0   A0A182Y8D8   A0A1L8DQU5   Q7Q1V0   A0A182L619   A0A1L8DQP5   A0A0L7QQI1   A0A2M4DMN4   A0A2M3Z177   A0A2M4AC36   A0A2M4ACK0   A0A2M4BML2   A0A2M4DMS1   A0A2M4DMQ3   A0A158NE94   E0VBI5   A0A0K8SY61   A0A336M9C7   A0A0A9VX47   A0A2J7QEQ5   D2T1A8   A0A3L8DBX5   E9IEL9   A0A0M8ZS78   A0A411G871   T1HJA0   A0A154PHX5   A0A023F4E1   B3MPM5   A0A2S2ND41   J9JRF8   A0A310SAX6   B4HWH1   B4Q8Q4   B3N935   Q9VL27   Q8MYY3   A0A1W4UUS4   B4NZ59   B4JP37   B4KHN3   B4G7B6   A0A2S2PVG7   A0A067RV68   A0A0C9R4U7   A0A1A9ZVN6   A0A1A9UT81   A0A3B0K177   A0A023ETE0   A0A3B0K9B0   A0A1A9WLA3   B4MUD8   A0A1A9Y6Y0   B4M8H2   B5DHX9   A0A088A332   A0A0K2T4T3   A0A182F2Q2   A0A182K027   A0A1S3DTP6   A0A182NB11   B0WEB8   A0A182RCD2   A0A1B0CBE8  

EC Number

3.2.1.-

Pubmed

28756777    23622113    22651552    26354079    20798317    21719571    + More
24508170    18362917    19820115    22516182    20075255    28004739    28648823    23537049    17510324    12364791    24438588    25244985    20966253    21347285    20566863    25401762    30249741    21282665    25474469    17994087    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    24845553    24945155    15632085    23185243   

EMBL

RSAL01000021    RVE52412.1    KZ149927    PZC77532.1    NWSH01001168    PCG72287.1    + More
GAIX01014012    JAA78548.1    AK401133    BAM17755.1    KQ458751    KPJ05313.1    GL445914    EFN88826.1    GL888182    EGI65714.1    KK107079    EZA60164.1    KQ980636    KYN14937.1    KQ971338    EFA01818.1    BT126814    AEE61776.1    GEZM01037887    JAV81864.1    NNAY01003983    OXU18533.1    LBMM01002203    KMQ95149.1    KB632308    ERL91995.1    GL437442    EFN70460.1    CVRI01000058    CRL02887.1    CH477342    EAT43068.1    GEDC01029663    GEDC01022894    JAS07635.1    JAS14404.1    AXCN02000647    KZ288322    PBC28159.1    GFDL01000485    JAV34560.1    KQ978023    KYM97921.1    GFDL01000468    JAV34577.1    AAAB01008980    APCN01005736    KQ982769    KYQ50857.1    ATLV01014759    KE524984    KFB39533.1    GFDF01005314    JAV08770.1    AXCM01001912    KQ976401    KYM92575.1    KQ981335    KYN42658.1    GFDF01005311    JAV08773.1    GFDF01005313    JAV08771.1    EAA14548.3    GFDF01005312    JAV08772.1    KQ414786    KOC60877.1    GGFL01014652    MBW78830.1    GGFM01001531    MBW22282.1    GGFK01004999    MBW38320.1    GGFK01005007    MBW38328.1    GGFJ01005176    MBW54317.1    GGFL01014653    MBW78831.1    GGFL01014654    MBW78832.1    ADTU01013175    DS235030    EEB10741.1    GBRD01007725    JAG58096.1    UFQS01000272    UFQT01000272    SSX02272.1    SSX22648.1    GBHO01043838    JAF99765.1    NEVH01015307    PNF27047.1    FM986353    CAX20733.1    QOIP01000010    RLU17408.1    GL762647    EFZ20978.1    KQ435878    KOX70065.1    MH366297    QBB02106.1    ACPB03006489    KQ434896    KZC10800.1    GBBI01002331    JAC16381.1    CH902620    EDV32273.1    GGMR01002419    MBY15038.1    ABLF02027051    ABLF02027053    KQ765605    OAD53851.1    CH480818    EDW52366.1    CM000361    CM002910    EDX04469.1    KMY89418.1    CH954177    EDV58470.2    AE014134    BT044084    AAF52871.2    ACH92149.1    AY113489    AAM29494.1    CM000157    EDW88754.1    CH916372    EDV99462.1    CH933807    EDW12312.1    CH479180    EDW28370.1    GGMS01000258    MBY69461.1    KK852444    KDR23774.1    GBYB01007777    JAG77544.1    OUUW01000006    SPP81610.1    GAPW01001944    JAC11654.1    SPP81611.1    CH963857    EDW76064.1    CH940654    EDW57498.2    CH379059    EDY69906.1    KRT03770.1    HACA01003085    CDW20446.1    DS231907    EDS45478.1    AJWK01005088   

Proteomes

UP000283053    UP000218220    UP000053268    UP000008237    UP000007755    UP000053097    + More
UP000078492    UP000007266    UP000002358    UP000215335    UP000036403    UP000030742    UP000000311    UP000183832    UP000008820    UP000075886    UP000242457    UP000078542    UP000075840    UP000075809    UP000030765    UP000075883    UP000078540    UP000078541    UP000075903    UP000075880    UP000076408    UP000007062    UP000075882    UP000053825    UP000005205    UP000009046    UP000235965    UP000279307    UP000053105    UP000015103    UP000076502    UP000007801    UP000007819    UP000001292    UP000000304    UP000008711    UP000000803    UP000192221    UP000002282    UP000001070    UP000009192    UP000008744    UP000027135    UP000092445    UP000078200    UP000268350    UP000091820    UP000007798    UP000092443    UP000008792    UP000001819    UP000005203    UP000069272    UP000075881    UP000079169    UP000075884    UP000002320    UP000075900    UP000092461   

PRIDE

Q8MYY3   

Pfam

PF17450   Melibiase_2_C        + More
PF16499   Melibiase_2
PF00402   Calponin
PF00307   CH
PF09174   Maf1

Interpro

IPR002241   Glyco_hydro_27        + More
IPR000111   Glyco_hydro_27/36_CS       
IPR013785   Aldolase_TIM       
IPR017853   Glycoside_hydrolase_SF       
IPR035373   Melibiase/NAGA_C       
IPR013780   Glyco_hydro_b       
IPR000557   Calponin_repeat       
IPR036872   CH_dom_sf       
IPR001715   CH-domain       
IPR038564   Maf1_sf       
IPR015257   Maf1       

SUPFAM

SSF51445   SSF51445        + More
SSF47576   SSF47576       

Gene 3D

2.60.40.1180     3.20.20.70     1.10.418.10     3.40.1000.50    

CDD

cd14792  GH27
cd00014  CH

ProteinModelPortal

A0A437BPU5   A0A2W1BQY8   A0A2A4JJP4   S4NSM8   I4DIL5   A0A0N1PES9   + More
E2B637   F4WJD6   A0A026WYH3   A0A151J0R5   D1ZZP5   J3JUA1   K7J2S2   A0A1Y1M843   A0A232EJJ6   A0A0J7KXZ7   U4UPP5   E2A7Y1   A0A1J1IRP1   Q17A03   A0A1B6CLQ8   A0A182Q255   A0A2A3EAC4   A0A1Q3G433   A0A195CCG6   A0A1Q3G451   A0A1S4H2E7   A0A182ICP7   A0A151WST7   A0A084VNI9   A0A1L8DR08   A0A182MV14   A0A195BWB5   A0A195FQA7   A0A1L8DQP1   A0A182VNL1   A0A182IPD0   A0A182Y8D8   A0A1L8DQU5   Q7Q1V0   A0A182L619   A0A1L8DQP5   A0A0L7QQI1   A0A2M4DMN4   A0A2M3Z177   A0A2M4AC36   A0A2M4ACK0   A0A2M4BML2   A0A2M4DMS1   A0A2M4DMQ3   A0A158NE94   E0VBI5   A0A0K8SY61   A0A336M9C7   A0A0A9VX47   A0A2J7QEQ5   D2T1A8   A0A3L8DBX5   E9IEL9   A0A0M8ZS78   A0A411G871   T1HJA0   A0A154PHX5   A0A023F4E1   B3MPM5   A0A2S2ND41   J9JRF8   A0A310SAX6   B4HWH1   B4Q8Q4   B3N935   Q9VL27   Q8MYY3   A0A1W4UUS4   B4NZ59   B4JP37   B4KHN3   B4G7B6   A0A2S2PVG7   A0A067RV68   A0A0C9R4U7   A0A1A9ZVN6   A0A1A9UT81   A0A3B0K177   A0A023ETE0   A0A3B0K9B0   A0A1A9WLA3   B4MUD8   A0A1A9Y6Y0   B4M8H2   B5DHX9   A0A088A332   A0A0K2T4T3   A0A182F2Q2   A0A182K027   A0A1S3DTP6   A0A182NB11   B0WEB8   A0A182RCD2   A0A1B0CBE8  

PDB

1KTC     E-value=8.81748e-127,     Score=1162

KEGG

101736031    K01204 alpha-N-acetylgalactosaminidase [EC:3.2.1.49] | (RefSeq) alpha-N-acetylgalactosaminidase-like

PATHWAY

00603    Glycosphingolipid biosynthesis - globo and isoglobo series - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04142    Lysosome - Bombyx mori (domestic silkworm)

GO

GO:0004553   GO:0005975   GO:0005737   GO:0009311   GO:0016139   GO:0004557   GO:0046477   GO:0016021   GO:0008152   GO:0016798   GO:0016480   GO:0003824   GO:0003917   GO:0016887   GO:0005634   GO:0030145   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR11452  

SignalP

Position:   1 - 24,         Likelihood:  0.980913

 

 

Length:

442

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

12.7427

Exp number, first 60 AAs:

12.45315

Total prob of N-in:

0.58749

POSSIBLE N-term signal

sequence

outside

1  -  442

 

 

Pi

267.802343

Theta

158.840899

Tajima's D

2.160061

CLR

0.238835

CSRT

0.903054847257637

Interpretation

Uncertain