Gene

KWMTBOMO08221

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr14(-):2189247-2189743      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

Mitochondrial   Reliability : 3.638

CDS

ATGCTGGGAGTCTTCAACAGAGCGAAGTGGTACTTCACGCTTGGACAAAGACATTTGCTTTACAAAGCACGGGTCCGGCCTCACGTGGAGTACTACTCCCATCTCTGGGCCGGGGCTCTGAAATACCAGCTACTTCCATTTGACTTCATACAGAAGAAGGCCGTTCGGATTATCGATAATCCCATTTTCATGGATCGTTTGGAATCTCTGGGTCTGCGGAGGGACTTCGGTTCCCTCTGTATTTTGTACCGTATGTTACATGGGGCACGTTTCCATAGATATTTTTGCCACGTACCATCCGGCTTTGGAATGTGCTCCCCTCTAAAACAAGCACGCACAGAATACGCGTAA

Protein

MLGVFNRAKWYFTLGQRHLLYKARVRPHVEYYSHLWAGALKYQLLPFDFIQKKAVRIIDNPIFMDRLESLGLRRDFGSLCILYRMLHGARFHRYFCHVPSGFGMCSPLKQARTEYA

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Uniprot

Q5KTM5   Q6UV17   A0A3S2KYN2   A0A437B9X9   A0A3S2LP03   A0A3S2LQP1   + More
A0A3S2P9Q3   A0A437ARI9   A0A437ARG3   A0A3S2NTH0   A0A437AY32   A0A437AZE5   A0A3S2NMS5   A0A3S2NHP4   A0A3S2NMX8   A0A437B259   A0A437BUJ7   A0A3D5S1K1   A0A2H1VFZ3   A0A437BF96   A0A2H1WAR9   A0A1Y1S3P2   A0A0P4VXU0   A0A2H1WCG9   J9GT67   B9WPT5   A0A2H1V2F4   A0A3M0KTC2   T2M6M7   K7EX79   A0A2D4K2I4   K7F0B4   A0A3M0K6V7   A0A3M0KGM7   K7F136   K7EWV4   K7FHG6   K7EXW6   K7F187   K7EYK2   A0A2I0U032   A0A093P063   K7EY85   K7EZN0   K7EYG1   A0A437B537   A0A2I0TRW1   A0A091JCI1   K7EX39   R4GDB2   K7EX24   A0A091M5Z1   A0A091IQ22   A0A3M0JLA9   A0A2I0UFL2   A0A2I0UEH1   A0A3M0K9P5  

EC Number

1.2.1.84

Pubmed

30148503    28345194    23251564    24065732    17381049    21881562    + More

EMBL

AB126052    BAD86652.1    AY359886    AAQ57129.1    RSAL01000487    RVE41561.1    + More
RSAL01000109    RVE47192.1    RSAL01002067    RVE40593.1    RSAL01000422    RVE41792.1    RSAL01000164    RVE45343.1    RSAL01002868    RVE40398.1    RSAL01002827    RVE40408.1    RSAL01000090    RVE48098.1    RSAL01000280    RVE43066.1    RSAL01000253    RVE43469.1    RSAL01000002    RVE54942.1    RSAL01003136    RVE40332.1    RVE55041.1    RVE55094.1    RSAL01000210    RVE44225.1    RSAL01000007    RVE54134.1    DPOC01000269    HCX22453.1    ODYU01002162    SOQ39302.1    RSAL01000072    RVE49051.1    ODYU01007424    SOQ50185.1    LWDP01000391    ORD92879.1    GDRN01105059    JAI57791.1    ODYU01007423    SOQ50184.1    AMCI01002135    EJX03495.1    FM995623    CAX36785.1    ODYU01000366    SOQ35027.1    QRBI01000102    RMC16528.1    HAAD01001474    CDG67706.1    AGCU01012855    IACL01033656    LAB02935.1    AGCU01032078    QRBI01000116    RMC08902.1    QRBI01000106    RMC12215.1    AGCU01063261    AGCU01000442    AGCU01203047    AGCU01033893    AGCU01066665    AGCU01035999    KZ506506    PKU39369.1    KL225273    KFW70433.1    AGCU01082246    AGCU01168699    AGCU01122093    RSAL01000157    RVE45592.1    KZ507616    PKU36473.1    KK501890    KFP18764.1    AGCU01040360    AAWZ02024500    AGCU01165999    KK520248    KFP66142.1    KK500813    KFP10422.1    QRBI01000136    RMC01723.1    KZ505800    PKU44826.1    KZ505829    PKU44419.1    QRBI01000113    RMC09825.1   

Proteomes

UP000283053    UP000269221    UP000007267    UP000054081    UP000053119    UP000001646    + More

PRIDE

Q5KTM5    Q6UV17   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF01585   G-patch
PF01873   eIF-5_eIF-2B
PF15613   WSD
PF04939   RRS1
PF07993   NAD_binding_4
PF02182   SAD_SRA
PF00097   zf-C3HC4
PF08159   NUC153
PF12335   SBF2
PF03456   uDENN
PF02141   DENN
PF15008   DUF4518

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR000504   RRM_dom       
IPR034653   SPF45_RRM       
IPR003954   RRM_dom_euk       
IPR000467   G_patch_dom       
IPR040052   RBM17       
IPR035979   RBD_domain_sf       
IPR016190   Transl_init_fac_IF2/IF5_Zn-bd       
IPR002735   Transl_init_fac_IF2/IF5       
IPR016189   Transl_init_fac_IF2/IF5_N       
IPR028941   WHIM2_dom       
IPR007023   Ribosom_reg       
IPR036291   NAD(P)-bd_dom_sf       
IPR013120   Male_sterile_NAD-bd       
IPR026055   FAR       
IPR028082   Peripla_BP_I       
IPR002347   SDR_fam       
IPR020904   Sc_DH/Rdtase_CS       
IPR013083   Znf_RING/FYVE/PHD       
IPR036987   SRA-YDG_sf       
IPR018957   Znf_C3HC4_RING-type       
IPR015947   PUA-like_sf       
IPR017907   Znf_RING_CS       
IPR001841   Znf_RING       
IPR003105   SRA_YDG       
IPR036322   WD40_repeat_dom_sf       
IPR040382   NOL10/Enp2       
IPR012580   NUC153       
IPR001680   WD40_repeat       
IPR030564   Myotubularin_fam       
IPR005113   uDENN_dom       
IPR022096   SBF1/SBF2       
IPR030567   MTMR13       
IPR037516   Tripartite_DENN       
IPR001194   cDENN_dom       
IPR005112   dDENN_dom       
IPR038751   Int8       
IPR026698   UPF_C3orf38       
IPR032710   NTF2-like_dom_sf       

SUPFAM

SSF56219   SSF56219        + More
SSF54928   SSF54928       
SSF75689   SSF75689       
SSF100966   SSF100966       
SSF51735   SSF51735       
SSF53822   SSF53822       
SSF88697   SSF88697       
SSF50978   SSF50978       
SSF54427   SSF54427       

Gene 3D

3.60.10.10     3.30.70.330     2.30.280.10     3.30.40.10    

CDD

cd12647  RRM_UHM_SPF45

ProteinModelPortal

Q5KTM5   Q6UV17   A0A3S2KYN2   A0A437B9X9   A0A3S2LP03   A0A3S2LQP1   + More
A0A3S2P9Q3   A0A437ARI9   A0A437ARG3   A0A3S2NTH0   A0A437AY32   A0A437AZE5   A0A3S2NMS5   A0A3S2NHP4   A0A3S2NMX8   A0A437B259   A0A437BUJ7   A0A3D5S1K1   A0A2H1VFZ3   A0A437BF96   A0A2H1WAR9   A0A1Y1S3P2   A0A0P4VXU0   A0A2H1WCG9   J9GT67   B9WPT5   A0A2H1V2F4   A0A3M0KTC2   T2M6M7   K7EX79   A0A2D4K2I4   K7F0B4   A0A3M0K6V7   A0A3M0KGM7   K7F136   K7EWV4   K7FHG6   K7EXW6   K7F187   K7EYK2   A0A2I0U032   A0A093P063   K7EY85   K7EZN0   K7EYG1   A0A437B537   A0A2I0TRW1   A0A091JCI1   K7EX39   R4GDB2   K7EX24   A0A091M5Z1   A0A091IQ22   A0A3M0JLA9   A0A2I0UFL2   A0A2I0UEH1   A0A3M0K9P5  

KEGG

105841744    no KO assigned | (RefSeq) uncharacterized LOC105841744

GO

GO:0003964   GO:0004519   GO:0003723   GO:0016021   GO:0046872   GO:0005634  

PANTHER

PTHR13288   PTHR17602   PTHR11011   PTHR14927   PTHR10807   PTHR10807:SF4   PTHR13350   PTHR21084  

Subcellular location

Nucleus  

Length:

116

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04681

Exp number, first 60 AAs:

0.02412

Total prob of N-in:

0.23330

outside

1  -  116

 

 

Pi

104.872419

Theta

89.957692

Tajima's D

0.50352

CLR

24.748276

CSRT

0.517174141292935

Interpretation

Uncertain