Gene

KWMTBOMO08207

Pre Gene Modal

BGIBMGA009464

Annotation

prothoracicostatic_peptide_precursor_[Bombyx_mori]

Location

Bomo_Chr14(-):1815650-1828866      View in EpiBrowser

Full name

Prothoracicostatic peptide       + More
Prothoracicostatic peptides      
DNA-directed RNA polymerase subunit      

Alternative Name

Bom-PTSP

Location in the cell

Extracellular   Reliability : 1.137 Nuclear   Reliability : 1.465

CDS

ATGCGTTGGTGTTTATTCGCGCTGTGGGTGTTCGGCGTGGCCACTGTGGTCACGGCTGCCGAGGAGCCTCATCATGACGCTGCGCCACAGACCGACAACGAAGTGGACTTAACAGAAGATGACAAGAGAGCCTGGAGCAGCCTGCACAGTGGATGGGCTAAACGCGCCTGGCAAGACATGAGTTCGGCATGGGGCAAGCGCGCATGGCAGGACCTCAACTCAGCATGGGGCAAGCGCGGATGGCAGGACTTGAACTCAGCTTGGGGCAAACGCGCATGGCAGGATCTTAACTCGGCATGGGGTAAAAGAGGCTGGCAAGATCTGAACTCTGCATGGGGCAAGCGCGATGATGATGAGGCTATGGAGAAAAAGAGTTGGCAAGATTTGAACTCCGTTTGGGGGAAACGTGCCTGGCAAGATCTGAACTCGGCCTGGGGCAAGCGCGCTTGGCAGGATCTGAATTCCGCCTGGGGAAAGCGAGGATGGAATGATATGAGCTCTGCTTGGGGCAAACGTGCCTGGCAAGACTTGAACTCTGCTTGGGGCAAACGCGCTTGGCAGGATATGAGCTCTGCTTGGGGAAAACAGGCACCTGAGAAGTGGGCAGCATTTCACGGTTCTTGGGGCAAGAGGTCCAGCATCGAACCGGATTACGAAGAAATTGACGCCGTAGAACAGCTCGTTCCTTACCAGCAGGTTCCTAACGAAGAACACATCGACGCTCCTGAGAAAAAGGCCTGGTCAGCCCTCCACGGAACCTGGGGCAAGAGACCGGTCAAACCTATGTTCAACAATGAACACAGCGCTACCACGAACGAGGCCTAA

Protein

MRWCLFALWVFGVATVVTAAEEPHHDAAPQTDNEVDLTEDDKRAWSSLHSGWAKRAWQDMSSAWGKRAWQDLNSAWGKRGWQDLNSAWGKRAWQDLNSAWGKRGWQDLNSAWGKRDDDEAMEKKSWQDLNSVWGKRAWQDLNSAWGKRAWQDLNSAWGKRGWNDMSSAWGKRAWQDLNSAWGKRAWQDMSSAWGKQAPEKWAAFHGSWGKRSSIEPDYEEIDAVEQLVPYQQVPNEEHIDAPEKKAWSALHGTWGKRPVKPMFNNEHSATTNEA

Description

Inhibits ecdysteroid biosynthesis in the prothoracic gland of fifth instar larvae, with maximum inhibition during the spinning stage. When administered to day 8 fifth instar larvae it produces a significant delay in the commencement spinning behavior.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic Activity

a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)

Similarity

Belongs to the RNA polymerase beta' chain family.

Keywords

Amidation   Cleavage on pair of basic residues   Complete proteome   Direct protein sequencing   Hormone   Reference proteome   Secreted   Signal   Neuropeptide  

Feature

peptide  Prothoracicostatic peptide

Uniprot

P82003   H9JIW3   A0A2A4IUD2   M4QC52   A0A0L7L571   A0A2W1BIY3   + More
A0A0S1U2B8   A0A3S2M672   A0A2H1VH50   C0HKW7   A0A194Q4I5   A0A0N0PBU8   U3U8S6   A0A1B6E152   A0A2R7WJ16   A0A2J7Q104   W8FR52   A0A169PWE1   A0A3S5HJS2   A0A146M0H5   A0A1S6JQ47   I3VN93   E0V982   A0A210PSH6   A0A2D2CNM0   A0A0S2YR70   A0A1X9WEB7   A0A1U7YUK7   A0A1Y1M489   A0A194XW81   A0A0P6BLA5   V4AR40   A0A1L8E9X1   A0A1L8E9S2   M4I0H3   A0A0P5YQL8   A0A1S3Y6X3   A0A210QT49   A0A346GAR7   A0A1L8EA89   A0A1L8E9X5   A0A1I8PDH1  

EC Number

2.7.7.6

Pubmed

10531308    15274176    19121390    26227816    28756777    29466015    + More
26354079    23932938    24467643    25401762    26823975    30467353    28082215    20566863    28812685    29077039    26592767    28502716    23773524    28004739    23254933    23569279    24807620   

EMBL

AB073553    BABH01023059    BABH01023060    NWSH01007070    PCG63106.1    KC340935    + More
AGH25567.1    JTDY01002951    KOB70429.1    KZ150093    PZC73665.1    KT005949    ALM30300.1    RSAL01000028    RVE51890.1    ODYU01002527    SOQ40137.1    KQ459585    KPI98320.1    KQ460889    KPJ11082.1    AB817265    BAO00962.1    GEDC01005653    JAS31645.1    KK854903    PTY19606.1    NEVH01019960    PNF22272.1    KF697189    GBHO01039136    GBHO01039135    GBHO01039134    GBRD01006050    GBRD01006049    GDHC01012791    GDHC01005749    GDHC01003966    AHK09726.1    JAG04468.1    JAG04469.1    JAG04470.1    JAG59771.1    JAQ05838.1    JAQ12880.1    JAQ14663.1    LC147082    BAU88428.1    MH311637    AZK31347.1    GDHC01005700    JAQ12929.1    KY288008    AQS80539.1    JQ864192    AFK81930.1    DS234991    EEB09938.1    NEDP02005525    OWF39428.1    MF579246    ATQ64324.1    KR078369    KX013558    ALQ28584.1    ANF04992.1    KY659251    ARS01352.1    GEZM01043886    JAV78686.1    KQ947404    KUJ24493.1    GDIP01013067    JAM90648.1    KB201305    ESO97295.1    GFDG01003268    JAV15531.1    GFDG01003269    JAV15530.1    JX513877    AFV92893.1    GDIP01068361    JAM35354.1    NEDP02002015    OWF51927.1    MH045202    AXN93470.1    GFDG01003270    JAV15529.1    GFDG01003271    JAV15528.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000283053    UP000053268    UP000053240    + More
UP000235965    UP000009046    UP000242188    UP000189701    UP000070700    UP000030746    UP000084051    UP000095300   

PRIDE

P82003    H9JIW3   

Pfam

PF08258   WWamide        + More
PF00623   RNA_pol_Rpb1_2
PF04983   RNA_pol_Rpb1_3
PF04997   RNA_pol_Rpb1_1
PF04998   RNA_pol_Rpb1_5

Interpro

IPR013271   WWamide_pept        + More
IPR006592   RNA_pol_N       
IPR000722   RNA_pol_asu       
IPR007066   RNA_pol_Rpb1_3       
IPR007080   RNA_pol_Rpb1_1       
IPR007081   RNA_pol_Rpb1_5       
IPR018247   EF_Hand_1_Ca_BS       
IPR011992   EF-hand-dom_pair       
IPR002048   EF_hand_dom       

SUPFAM

SSF47473   SSF47473       

ProteinModelPortal

P82003   H9JIW3   A0A2A4IUD2   M4QC52   A0A0L7L571   A0A2W1BIY3   + More
A0A0S1U2B8   A0A3S2M672   A0A2H1VH50   C0HKW7   A0A194Q4I5   A0A0N0PBU8   U3U8S6   A0A1B6E152   A0A2R7WJ16   A0A2J7Q104   W8FR52   A0A169PWE1   A0A3S5HJS2   A0A146M0H5   A0A1S6JQ47   I3VN93   E0V982   A0A210PSH6   A0A2D2CNM0   A0A0S2YR70   A0A1X9WEB7   A0A1U7YUK7   A0A1Y1M489   A0A194XW81   A0A0P6BLA5   V4AR40   A0A1L8E9X1   A0A1L8E9S2   M4I0H3   A0A0P5YQL8   A0A1S3Y6X3   A0A210QT49   A0A346GAR7   A0A1L8EA89   A0A1L8E9X5   A0A1I8PDH1  

KEGG

692434    no KO assigned | (RefSeq) PTSP, ALL-B; prothoracicostatic peptide

GO

GO:0005615   GO:0002168   GO:0005179   GO:0007218   GO:0005576   GO:0006351   GO:0003677   GO:0003899   GO:0016021   GO:0005509  

Subcellular location

Secreted  

SignalP

Position:   1 - 19,         Likelihood:  0.997173

 

 

Length:

274

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.04335

Exp number, first 60 AAs:

1.04335

Total prob of N-in:

0.07496

outside

1  -  274

 

 

Pi

21.479017

Theta

157.733858

Tajima's D

0.298741

CLR

17.898021

CSRT

0.450277486125694

Interpretation

Uncertain