Gene

KWMTBOMO08201  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009467

Annotation

PREDICTED:_glucosamine-6-phosphate_isomerase_isoform_X2_[Papilio_machaon]

Location

Bomo_Chr14(-):1673889-1682339      View in EpiBrowser

Full name

Glucosamine-6-phosphate isomerase       + More
Glucosamine-6-phosphate isomerase 2      

Alternative Name

Glucosamine-6-phosphate deaminase
Glucosamine-6-phosphate deaminase 2

Location in the cell

Cytoplasmic   Reliability : 3.04

CDS

ATGCGTCTTATAATTCTCGAAGATGCCAGCATCGTTGCCGACTGGGCCGCCAGATTCGTTCTCCAGCGGATCACGCAGTTCGCTCCGGGTCCGGGAAGACACTTCGTGCTGGGCCTGCCCACCGGTGGGACGCCCCTCGGCATGTACAAACGGTTGATAGAGTTCCACAAGGAAGGGAAGTTATCTTTCAAATATGTGACCACTTTCAACATGGACGAGTATGTGGGTCTTCCCCGTGACCATCCCGAGTCCTACCACTACTACATGTGGAACGAGTTCTTCAAACACATCGACATAGAGCCGAGCAACGCGCACGTGCTCGACGGCAACGCATCCGATTTAGTGCTCGAGTGTCAACGCTTTGAGAAACTCATACAGGAGGCTGGCGGAGTGCATTTGTTCATCGGAGGTATCGGTCCGGACGGTCACATCGCGTTCAACGAACCGGGCTCCTCGCTGGTGTCTCGGACGCGAGTGAAGACCCTGGCCTACGACACCCTGGACGCCAACAAGCGGTTCTTTGACAACGACATCAGCAAGGTGCCCCGACAGGCGCTCACCGTTGGAGTCGGAACTGTTATGGACGCTAAAGAGGTCATGATCCTCATAACAGGAGTGCACAAGTCCTTGGCGCTTGCCAAGGCTGTGGAGGAAGGCGTGAACCACATGTGGACGGTGTCGGCCTTCCAGCAACATCCTCAAGCGCTTTTCGTGTGTGACGAAGACGCCACACTCGAGTTGAGGGTCAAAACAGTTAAATACTTTAAGAGTTTAATGGTGGAACACAATAAACTGATAGAAGCAAAACAATGA

Protein

MRLIILEDASIVADWAARFVLQRITQFAPGPGRHFVLGLPTGGTPLGMYKRLIEFHKEGKLSFKYVTTFNMDEYVGLPRDHPESYHYYMWNEFFKHIDIEPSNAHVLDGNASDLVLECQRFEKLIQEAGGVHLFIGGIGPDGHIAFNEPGSSLVSRTRVKTLAYDTLDANKRFFDNDISKVPRQALTVGVGTVMDAKEVMILITGVHKSLALAKAVEEGVNHMWTVSAFQQHPQALFVCDEDATLELRVKTVKYFKSLMVEHNKLIEAKQ

Catalytic Activity

alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)

Subunit

Homohexamer.

Similarity

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.

Keywords

Carbohydrate metabolism   Coiled coil   Complete proteome   Cytoplasm   Hydrolase   Reference proteome   Alternative splicing  

Feature

chain  Glucosamine-6-phosphate isomerase 2
splice variant  In isoform A.

Uniprot

H9JIW6   A0A222AJ35   A0A2A4JPG6   A0A2H1VU62   A0A437B3V5   A0A2A4JPB1   + More
A0A212EWA6   A0A2W1BEV1   A0A194PZ46   S4PE45   A0A1J1IPS7   D2A2L2   A0A336LU61   A0A0Q9WBD5   A0A0P8XV28   A0A034WAS0   A0A0K8VDI5   A0A3B0KEY2   A0A0Q9X5S1   A0A1L5L9D6   A0A0R3NXV6   A0A0A1WQ03   A0A1W4XHB0   W8BZB0   A0A0C9RLV6   M9ND31   A0A1B6F5M2   A0A0M4E313   A0A1W4UIY2   V5FZ40   A0A336LLF8   A0A0R1DSK6   A0A1I8MDQ5   A0A034WDD6   A0A0K8UEW5   A0A1B6H960   W8BS96   U5EY06   A0A0Q5WIN9   E0VTH1   A0A0J9TG94   A0A0A1XQ14   A4IHW6   B4LU11   A0A2J7PZD3   A0A0P8ZES1   B4KF38   A0A1L8E1Z9   A0A2P8Y487   A0A0P5S8V7   B3MMZ7   A0A0L0CAZ7   A0A0R3NRD4   A0A1B6DAT5   B4GJK4   A0A3B0K811   A0A1L8HTM5   Q6PA43   E9G0Q9   A0A1B6L607   A0A1I8PZ69   Q29NT9   D3TP29   A0A0P5XS92   A0A1B6KT34   A0A1I8MDR2   A0A1Y1L0K0   B0WKW4   A0A250YE98   A0A411G6A4   W5J8R2   A0A158P2B3   A0A3Q3J3M3   A0A2U3V426   A0A340WTF3   A0A2Y9MIC1   A0A384A0B1   A0A2Y9TFS2   A0A341AA49   Q16HW7-3   F1S3T0   A0A1S2ZYD2   A0A2M4BWA9   A0A2K5RPG0   A0A195D4E5   G3VGH7   A0A1B0D5D0   F4W6K8   A0A2M4ALC9   E2RH59   A0A3Q7UXB9   H0XBH9   M3X7J4   A0A195FJ62   F6VG59   A0A2M4CQE3   A0A1U7RPC2   A0A1S4JMR1   A0A3Q3AFG7   B4JAF1  

EC Number

3.5.99.6

Pubmed

19121390    22118469    28756777    26354079    23622113    18362917    + More
19820115    17994087    25348373    18057021    15632085    25830018    24495485    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    25315136    20566863    22936249    29403074    26108605    27762356    21292972    20353571    28004739    28087693    20920257    23761445    21347285    17510324    21709235    21719571    16341006    17975172    19892987   

EMBL

BABH01023047    KY563981    KY609555    ASO76387.1    ASO76419.1    NWSH01000904    + More
PCG73598.1    ODYU01004479    SOQ44391.1    RSAL01000178    RVE44994.1    PCG73596.1    AGBW02012057    OWR45751.1    KZ150093    PZC73659.1    KQ459585    KPI98313.1    GAIX01003331    JAA89229.1    CVRI01000057    CRL02243.1    KQ971338    EFA02005.2    UFQT01000004    SSX17188.1    CH940649    KRF81997.1    CH902620    KPU73189.1    GAKP01007168    JAC51784.1    GDHF01023457    GDHF01019871    GDHF01016833    GDHF01015310    JAI28857.1    JAI32443.1    JAI35481.1    JAI37004.1    OUUW01000006    SPP82168.1    CH933807    KRG03551.1    KU323592    APO36902.1    CH379058    KRT03651.1    GBXI01013697    JAD00595.1    GAMC01004537    JAC02019.1    GBYB01014337    JAG84104.1    AE014134    AFH03572.1    GECZ01024269    JAS45500.1    CP012523    ALC40116.1    GALX01005521    JAB62945.1    SSX17187.1    CM000157    KRJ98096.1    GAKP01007169    JAC51783.1    GDHF01027454    GDHF01023575    GDHF01012610    GDHF01003986    JAI24860.1    JAI28739.1    JAI39704.1    JAI48328.1    GECU01036516    JAS71190.1    GAMC01004538    JAC02018.1    GANO01002257    JAB57614.1    CH954177    KQS70185.1    DS235765    EEB16677.1    CM002910    KMY88320.1    GBXI01001337    JAD12955.1    BC135724    EDW65064.2    NEVH01020335    PNF21682.1    KPU73187.1    EDW13021.2    GFDF01001347    JAV12737.1    PYGN01000947    PSN39082.1    GDIQ01209118    GDIP01142908    JAK42607.1    JAL60806.1    EDV31022.1    KPU73186.1    JRES01000668    KNC29407.1    KRT03650.1    GEDC01029595    GEDC01025620    GEDC01019562    GEDC01014494    GEDC01013490    GEDC01001607    GEDC01000886    JAS07703.1    JAS11678.1    JAS17736.1    JAS22804.1    JAS23808.1    JAS35691.1    JAS36412.1    CH479184    EDW36820.1    SPP82169.1    CM004466    OCT99466.1    BC060461    GL732528    EFX86948.1    GEBQ01020892    GEBQ01001779    JAT19085.1    JAT38198.1    EZ423181    ADD19457.1    GDIP01068265    LRGB01001581    JAM35450.1    KZS11259.1    GEBQ01025416    JAT14561.1    GEZM01068174    JAV67114.1    DS231977    EDS30096.1    GFFW01002841    JAV41947.1    MH365611    QBB01420.1    ADMH02002094    ETN59265.1    ADTU01007051    CH478133    AEMK02000064    GGFJ01008216    MBW57357.1    KQ976885    KYN07304.1    AEFK01217617    AEFK01217618    AEFK01217619    AJVK01025142    GL887707    EGI70343.1    GGFK01008268    MBW41589.1    AAEX03009029    AAQR03112932    AAQR03112933    AANG04001605    KQ981523    KYN40302.1    GGFL01003378    MBW67556.1    CH916368    EDW03822.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000007151    UP000053268    UP000183832    + More
UP000007266    UP000008792    UP000007801    UP000268350    UP000009192    UP000001819    UP000192223    UP000000803    UP000092553    UP000192221    UP000002282    UP000095301    UP000008711    UP000009046    UP000008143    UP000235965    UP000245037    UP000037069    UP000008744    UP000186698    UP000000305    UP000095300    UP000076858    UP000002320    UP000000673    UP000005205    UP000261600    UP000245320    UP000265300    UP000248483    UP000261681    UP000248484    UP000252040    UP000008820    UP000008227    UP000079721    UP000233040    UP000078542    UP000007648    UP000092462    UP000007755    UP000002254    UP000286640    UP000005225    UP000011712    UP000078541    UP000002281    UP000189705    UP000264800    UP000001070   

PRIDE

H9JIW6    A4IHW6    B4LU11    B4KF38    B3MMZ7    B4GJK4    + More
Q6PA43    Q29NT9    D3TP29    F1S3T0    G3VGH7    E2RH59    F6VG59    B4JAF1   

Pfam

PF01182   Glucosamine_iso

Interpro

IPR037171   NagB/RpiA_transferase-like        + More
IPR006148   Glc/Gal-6P_isomerase       
IPR018321   Glucosamine6P_isomerase_CS       
IPR004547   Glucosamine6P_isomerase       

SUPFAM

SSF100950   SSF100950       

CDD

cd01399  GlcN6P_deaminase

ProteinModelPortal

H9JIW6   A0A222AJ35   A0A2A4JPG6   A0A2H1VU62   A0A437B3V5   A0A2A4JPB1   + More
A0A212EWA6   A0A2W1BEV1   A0A194PZ46   S4PE45   A0A1J1IPS7   D2A2L2   A0A336LU61   A0A0Q9WBD5   A0A0P8XV28   A0A034WAS0   A0A0K8VDI5   A0A3B0KEY2   A0A0Q9X5S1   A0A1L5L9D6   A0A0R3NXV6   A0A0A1WQ03   A0A1W4XHB0   W8BZB0   A0A0C9RLV6   M9ND31   A0A1B6F5M2   A0A0M4E313   A0A1W4UIY2   V5FZ40   A0A336LLF8   A0A0R1DSK6   A0A1I8MDQ5   A0A034WDD6   A0A0K8UEW5   A0A1B6H960   W8BS96   U5EY06   A0A0Q5WIN9   E0VTH1   A0A0J9TG94   A0A0A1XQ14   A4IHW6   B4LU11   A0A2J7PZD3   A0A0P8ZES1   B4KF38   A0A1L8E1Z9   A0A2P8Y487   A0A0P5S8V7   B3MMZ7   A0A0L0CAZ7   A0A0R3NRD4   A0A1B6DAT5   B4GJK4   A0A3B0K811   A0A1L8HTM5   Q6PA43   E9G0Q9   A0A1B6L607   A0A1I8PZ69   Q29NT9   D3TP29   A0A0P5XS92   A0A1B6KT34   A0A1I8MDR2   A0A1Y1L0K0   B0WKW4   A0A250YE98   A0A411G6A4   W5J8R2   A0A158P2B3   A0A3Q3J3M3   A0A2U3V426   A0A340WTF3   A0A2Y9MIC1   A0A384A0B1   A0A2Y9TFS2   A0A341AA49   Q16HW7-3   F1S3T0   A0A1S2ZYD2   A0A2M4BWA9   A0A2K5RPG0   A0A195D4E5   G3VGH7   A0A1B0D5D0   F4W6K8   A0A2M4ALC9   E2RH59   A0A3Q7UXB9   H0XBH9   M3X7J4   A0A195FJ62   F6VG59   A0A2M4CQE3   A0A1U7RPC2   A0A1S4JMR1   A0A3Q3AFG7   B4JAF1  

PDB

1NE7     E-value=1.11342e-112,     Score=1038

KEGG

101746460    K02564 glucosamine-6-phosphate deaminase [EC:3.5.99.6] | (RefSeq) glucosamine-6-phosphate isomerase

PATHWAY

00520    Amino sugar and nucleotide sugar metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0006044   GO:0005737   GO:0004342   GO:0005975   GO:0006046   GO:0042802   GO:0006043   GO:0006048   GO:0019262   GO:0006091   GO:0046983   GO:0005515   GO:0005634   GO:0030145   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR11280  

Subcellular location

Cytoplasm  

Length:

270

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02546

Exp number, first 60 AAs:

0.01629

Total prob of N-in:

0.01966

outside

1  -  270

 

 

Pi

294.583983

Theta

184.80966

Tajima's D

1.598095

CLR

0.156018

CSRT

0.810159492025399

Interpretation

Uncertain