Gene

KWMTBOMO08167

Annotation

PREDICTED:_RING_finger_protein_121_isoform_X2_[Papilio_xuthus]

Location

Bomo_Chr14(+):334020-339621      View in EpiBrowser

Full name

RING finger protein 121      

Location in the cell

PlasmaMembrane   Reliability : 4.761

CDS

ATGGACCTTCACCGACCGGTGGATCCTAACAAGACATACCAGGAGCTGACGTCTGAGGAGAGATTGAGATATGATCACCAGAAATTGCATGAACTCCACAAAGGCCATGAATCAATGCATACAACTATGGTCTTAATATTAATAGGAGCACTTGTAATTTCACAAGTTGTCATTGTCCAATGGAAGAAACGACATTATAGGTCATATGCTTTCTTCACAATGATCGCCATGTGGTCCATCCCAGTCATGATAAGCTTTAAAAACGGTTGGTGGAGATTTGTTTCAATTTGGAGTGTATTCACACTCCTTACAGCTCTAGTCATTAGAAAAAGTTCAATTAAGCCAATGTCTGCTACTACGCCTAGATTAGTGTACAAATGGTTTTATTTAATATATAAAGTTTGCTGTTTTGTTGGTGTGTTTGGTTACATACTGATGATGCTTACAATGCTCGGCGTCAACTTGATGTTCGGACAGAAGCCCCAAGTCTGGATGGACATAGCTATATTATTTTTGTTTAACGGCTTGTACTTCGGAGTACTAGGGAGGGATGTTGCTGAATATTGCACCGATCAAATGGCAGCATCCATCGGGTACTACACGAAGGAGGGCATACCGACTCGGCAGCTGGAGAGCGACGTGTGCGCCGTGTGCGGGGCCGCGCTGTTGGTGCCGGTGCACGAGGAGGGCGTGCTGGAAAACACATACAAGCTGCCGTGCGGACATGTCTTCCACGAGTTCTGCATCCGGGGCTGGTGCATAGTCGGCAAGAAGCAGACGTGTCCGTATTGCAAAGAGAAGGTGGACCTCAAGCTGATGTTCACGAACCCTTGGGACCGTCCGCACATCATGTACGGCCAGCTGCTGGACTGGATCCGCTGGCTGGTGGCGTGGCAGCCGCTCGTCATGTTCCTCGTGCAGGGAGTCAACTGGTTGTTTGGACTTGAATGA

Protein

MDLHRPVDPNKTYQELTSEERLRYDHQKLHELHKGHESMHTTMVLILIGALVISQVVIVQWKKRHYRSYAFFTMIAMWSIPVMISFKNGWWRFVSIWSVFTLLTALVIRKSSIKPMSATTPRLVYKWFYLIYKVCCFVGVFGYILMMLTMLGVNLMFGQKPQVWMDIAILFLFNGLYFGVLGRDVAEYCTDQMAASIGYYTKEGIPTRQLESDVCAVCGAALLVPVHEEGVLENTYKLPCGHVFHEFCIRGWCIVGKKQTCPYCKEKVDLKLMFTNPWDRPHIMYGQLLDWIRWLVAWQPLVMFLVQGVNWLFGLE

Similarity

Belongs to the RNF121 family.

Keywords

Membrane   Metal-binding   Transmembrane   Transmembrane helix   Zinc   Zinc-finger   Complete proteome   Reference proteome  

Feature

chain  RING finger protein 121

Uniprot

A0A2H1WXY5   A0A1E1W7K1   A0A437BLK4   A0A2W1BHK1   A0A0N1PHF8   A0A2A4J131   + More
U5EID3   A0A084VNE2   A0A182MQN0   A0A182RC78   A0A0L0C3W6   A0A1S4GX30   A0A182URG0   A0A182JR62   A0A182WUA2   A0A182L1R4   A0A182HUX0   A0A1L8DSJ4   Q7Q3T8   A0A336KLP2   A0A1Q3FCT6   A0A1Q3FE71   B0WJ86   A0A336MEL6   A0A182JC57   A0A182NTR6   A0A182F619   A0A1S4G7J7   A0A2M4AU93   A0A2M4BUD2   B4Q2K9   A0A182UK93   A0A1B0DJB2   W5JN97   B3NWY2   B4I6K3   Q9VX13   A0A0M3QZF3   B4MAD1   B3MQX1   B4L6D7   A0A1W4VCF8   Q95SS4   B4NC02   A0A0K8VZY3   A0A034VIW5   D2A3I4   W8AZB1   A0A3B0K2S3   A0A067RT17   Q29G69   A0A182W7A7   A0A194PZW9   E0VBI8   A0A1B6DMA0   A0A1I8P3E7   A0A0K8TP46   A0A0T6BAF6   A0A1Y1NH25   A0A1I8N6V8   A0A1A9VZH4   A0A232FJ52   Q8IQZ5   K7J512   A0A1A9VS05   A0A158NXK0   A0A1A9XX28   A0A1B0BQS8   A0A1A9ZJZ3   D3TNX5   E2C1D0   A0A182P4V4   A0A182HFI1   A0A182QQX4   U4U042   E2A2F2   A0A151WKZ3   B4JK04   J3JW79   A0A1B6GRW7   A0A182S9U5   A0A1B6KXG5   A0A3L8E2M7   A0A1J1IQS4   T1IV29   A0A151INP8   A0A195BMR2   A0A195FF66   E9IVU9   A0A1Q3FD52   A0A1Q3FDI6   F4WQ12   A0A0P4VYQ7   A0A195ECT3   A0A1L8FQ75   Q6DD32   A0A1B8XXF7   Q6P360   N6UDA7   Q6PF25  

Pubmed

28756777    26354079    24438588    26108605    12364791    20966253    + More
17994087    17550304    20920257    23761445    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    18057021    25348373    18362917    19820115    24495485    24845553    15632085    20566863    26369729    28004739    25315136    28648823    20075255    21347285    20353571    20798317    26483478    23537049    22516182    30249741    21282665    21719571    27762356    20431018   

EMBL

ODYU01011849    SOQ57826.1    GDQN01008084    GDQN01001180    JAT82970.1    JAT89874.1    + More
RSAL01000037    RVE51189.1    KZ150088    PZC73741.1    KQ460889    KPJ11053.1    NWSH01004186    PCG65378.1    GANO01002682    JAB57189.1    ATLV01014737    KE524984    KFB39486.1    AXCM01001558    JRES01000940    KNC26985.1    AAAB01008964    APCN01002480    GFDF01004713    JAV09371.1    EAA12315.3    UFQS01000560    UFQT01000560    SSX04952.1    SSX25314.1    GFDL01009659    JAV25386.1    GFDL01009253    JAV25792.1    DS231957    EDS29011.1    UFQT01001049    SSX28626.1    GGFK01011026    MBW44347.1    GGFJ01007536    MBW56677.1    CM000162    EDX02650.1    AJVK01006313    ADMH02000877    ETN64788.1    CH954180    EDV46529.1    CH480823    EDW55951.1    AE014298    BT044195    AAF48770.1    AAN09594.1    ACH92260.1    CP012528    ALC49323.1    CH940655    EDW66190.1    KRF82594.1    CH902622    EDV34176.1    CH933812    EDW05933.1    AY060612    AAL28160.1    CH964239    EDW82361.1    GDHF01007918    JAI44396.1    GAKP01017227    GAKP01017224    GAKP01017219    JAC41725.1    KQ971338    EFA01904.1    GAMC01014973    JAB91582.1    OUUW01000003    SPP77698.1    KK852480    KDR22964.1    CH379064    EAL32241.1    KQ459585    KPI98289.1    DS235030    EEB10744.1    GEDC01010526    JAS26772.1    GDAI01001665    JAI15938.1    LJIG01002663    KRT84277.1    GEZM01002910    JAV97069.1    NNAY01000121    OXU30774.1    AAN09596.1    ADTU01003125    JXJN01018766    CCAG010011010    EZ423127    ADD19403.1    GL451921    EFN78237.1    JXUM01134342    KQ568107    KXJ69133.1    AXCN02000801    KB631736    ERL85668.1    GL436038    EFN72355.1    KQ983001    KYQ48451.1    CH916370    EDV99906.1    BT127497    AEE62459.1    GECZ01004587    JAS65182.1    GEBQ01024033    JAT15944.1    QOIP01000001    RLU26886.1    CVRI01000057    CRL02496.1    JH431572    KQ976940    KYN06968.1    KQ976441    KYM86421.1    KQ981610    KYN39335.1    GL766449    EFZ15245.1    GFDL01009617    JAV25428.1    GFDL01009405    JAV25640.1    GL888262    EGI63710.1    GDRN01086587    JAI61146.1    KQ979074    KYN22921.1    CM004477    OCT73742.1    BC077797    KV460878    OCA15352.1    BC064173    APGK01039539    KB740971    ENN76637.1    BC057753    CM004476    AAH57753.1    OCT75314.1   

Proteomes

UP000283053    UP000053240    UP000218220    UP000030765    UP000075883    UP000075900    + More
UP000037069    UP000075903    UP000075881    UP000076407    UP000075882    UP000075840    UP000007062    UP000002320    UP000075880    UP000075884    UP000069272    UP000002282    UP000075902    UP000092462    UP000000673    UP000008711    UP000001292    UP000000803    UP000092553    UP000008792    UP000007801    UP000009192    UP000192221    UP000007798    UP000007266    UP000268350    UP000027135    UP000001819    UP000075920    UP000053268    UP000009046    UP000095300    UP000095301    UP000091820    UP000215335    UP000002358    UP000078200    UP000005205    UP000092443    UP000092460    UP000092445    UP000092444    UP000008237    UP000075885    UP000069940    UP000249989    UP000075886    UP000030742    UP000000311    UP000075809    UP000001070    UP000075901    UP000279307    UP000183832    UP000078542    UP000078540    UP000078541    UP000007755    UP000078492    UP000186698    UP000008143    UP000019118   

PRIDE

Q9VX13    Q95SS4    Q8IQZ5   

Pfam

PF13639   zf-RING_2        + More
PF01399   PCI
PF18420   CSN4_RPN5_eIF3a
PF14721   AIF_C
PF07992   Pyr_redox_2

Interpro

IPR040176   RNF121/RNF175        + More
IPR001841   Znf_RING       
IPR013083   Znf_RING/FYVE/PHD       
IPR000717   PCI_dom       
IPR036390   WH_DNA-bd_sf       
IPR036388   WH-like_DNA-bd_sf       
IPR041406   CSN4_HTH       
IPR040134   PSMD12/CSN4       
IPR037754   CSN4       
IPR023753   FAD/NAD-binding_dom       
IPR036188   FAD/NAD-bd_sf       
IPR020846   MFS_dom       
IPR029324   AIF_C       
IPR016156   FAD/NAD-linked_Rdtase_dimer_sf       

SUPFAM

SSF46785   SSF46785        + More
SSF51905   SSF51905       
SSF55424   SSF55424       

Gene 3D

3.30.40.10     1.10.10.10     3.30.390.30     3.50.50.60    

CDD

cd06174  MFS

ProteinModelPortal

A0A2H1WXY5   A0A1E1W7K1   A0A437BLK4   A0A2W1BHK1   A0A0N1PHF8   A0A2A4J131   + More
U5EID3   A0A084VNE2   A0A182MQN0   A0A182RC78   A0A0L0C3W6   A0A1S4GX30   A0A182URG0   A0A182JR62   A0A182WUA2   A0A182L1R4   A0A182HUX0   A0A1L8DSJ4   Q7Q3T8   A0A336KLP2   A0A1Q3FCT6   A0A1Q3FE71   B0WJ86   A0A336MEL6   A0A182JC57   A0A182NTR6   A0A182F619   A0A1S4G7J7   A0A2M4AU93   A0A2M4BUD2   B4Q2K9   A0A182UK93   A0A1B0DJB2   W5JN97   B3NWY2   B4I6K3   Q9VX13   A0A0M3QZF3   B4MAD1   B3MQX1   B4L6D7   A0A1W4VCF8   Q95SS4   B4NC02   A0A0K8VZY3   A0A034VIW5   D2A3I4   W8AZB1   A0A3B0K2S3   A0A067RT17   Q29G69   A0A182W7A7   A0A194PZW9   E0VBI8   A0A1B6DMA0   A0A1I8P3E7   A0A0K8TP46   A0A0T6BAF6   A0A1Y1NH25   A0A1I8N6V8   A0A1A9VZH4   A0A232FJ52   Q8IQZ5   K7J512   A0A1A9VS05   A0A158NXK0   A0A1A9XX28   A0A1B0BQS8   A0A1A9ZJZ3   D3TNX5   E2C1D0   A0A182P4V4   A0A182HFI1   A0A182QQX4   U4U042   E2A2F2   A0A151WKZ3   B4JK04   J3JW79   A0A1B6GRW7   A0A182S9U5   A0A1B6KXG5   A0A3L8E2M7   A0A1J1IQS4   T1IV29   A0A151INP8   A0A195BMR2   A0A195FF66   E9IVU9   A0A1Q3FD52   A0A1Q3FDI6   F4WQ12   A0A0P4VYQ7   A0A195ECT3   A0A1L8FQ75   Q6DD32   A0A1B8XXF7   Q6P360   N6UDA7   Q6PF25  

PDB

5D0M     E-value=4.83939e-05,     Score=110

KEGG

101735881    K15698 RING finger protein 121 | (RefSeq) RING finger protein 121

GO

GO:0046872   GO:0016021   GO:0016874   GO:0030433   GO:0061630   GO:0000139   GO:0030968   GO:0005789   GO:0005737   GO:0008270   GO:0050660   GO:0046983   GO:0016491   GO:0019228   GO:1903069   GO:0072659   GO:0001966   GO:0005515   GO:0030286   GO:0016791   GO:0005634   GO:0030145   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR13407   PTHR10855   PTHR10855:SF2  

Subcellular location

Cytoplasm  
Membrane  

Length:

316

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

121.06995

Exp number, first 60 AAs:

20.71972

Total prob of N-in:

0.00066

POSSIBLE N-term signal

sequence

outside

1  -  38

TMhelix

39  -  61

inside

62  -  67

TMhelix

68  -  85

outside

86  -  88

TMhelix

89  -  108

inside

109  -  127

TMhelix

128  -  150

outside

151  -  162

TMhelix

163  -  182

inside

183  -  290

TMhelix

291  -  313

outside

314  -  316

 

 

Pi

244.688531

Theta

189.702675

Tajima's D

0.868228

CLR

0.137328

CSRT

0.627868606569671

Interpretation

Uncertain