Gene

KWMTBOMO08161

Annotation

putative_dynein?_axonemal?_heavy_polypeptide_1_[Danaus_plexippus]

Location

Bomo_Chr14(-):271557-273549      View in EpiBrowser

Full name

SAGA-associated factor 11 homolog      

Location in the cell

Cytoplasmic   Reliability : 3.109

CDS

ATGAAGGAGAGACACTGGAACGAGTTCATGGAGAAAGCCGGTATAACCCTGACCATGAACGAGAAGCAGACGTTCGACATGTGTCTCAAGCAAGGCGTCGGCAAACACGGCGACCTCATCGCGCAGATCGGTGAGCTCGCTTCCAAGGAGTACGTCATCGAGCAGGCCCTGGACAAGATGCAGACGGACTGGGCCACCAAGACCATGGAGATCACGCCTTACAAGAACACCGGAACGTACATGATGAAGGTCCCCGACGAGACCCTCCAGTTGTTGGACGAGCACCTGCTGGCCACCCAGCAACTCGGCTTCAGTCCGTTCAAAGCTGCCTTTGAACTCCGTATCGAGGAGTGGGACAGCAAGTTGAGGATGATGCAGATGGTTCTGGATGAATGGATCGAATGCCAGAAGGACTGGATGTACCTAGAGCCTATATTTACGTCGGAGGACATCTCCAGACAGCTCCCCTTCGAGGCGAAGAAGTACGGGACCATGGAGAGGATATGGAGGAGGATCATGGGGACGGCGGCCGCGTGTCCCAAGATGCTGGCGAGCGCGGAGGGCGCGGTGCTGGAGAGCGTGCGGGAGGCGCGCGGGCTGCTGGCGGCGGTGGCGCGCGGCCTGGCGCACTACACGGCGCGGAAGAGGCTCTGCTTCCCGCGCTTCTTCTTCCTCAGCGACGACGACCTGCTGCTCATCCTGGCGCACGCGCGGGACCCCGCCTCCGTCCAGCCGCATCTCAAGAAGTGTTTCGAGAATATTGCCAAGGTTCGTCTATCTTATCTTATATCTTTAAACGAGCAATTTTTGTATATATATAATATGAATCTCGGAAACGGCCCCAACGAGTTTCATAAGATTTAG

Protein

MKERHWNEFMEKAGITLTMNEKQTFDMCLKQGVGKHGDLIAQIGELASKEYVIEQALDKMQTDWATKTMEITPYKNTGTYMMKVPDETLQLLDEHLLATQQLGFSPFKAAFELRIEEWDSKLRMMQMVLDEWIECQKDWMYLEPIFTSEDISRQLPFEAKKYGTMERIWRRIMGTAAACPKMLASAEGAVLESVREARGLLAAVARGLAHYTARKRLCFPRFFFLSDDDLLLILAHARDPASVQPHLKKCFENIAKVRLSYLISLNEQFLYIYNMNLGNGPNEFHKI

Description

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.

Subunit

Component of some SAGA transcription coactivator-HAT complexes. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).

Similarity

Belongs to the SGF11 family.

Uniprot

A0A2A4JDQ9   A0A2A4JD05   A0A2A4JE46   A0A2H1VXK0   H9JXU6   A0A3S2M4I0   + More
A0A1B6E076   A0A1B6CKQ5   A0A1B6F3E5   A0A2P8YP94   A7S0X9   E0VBG0   H3BFH9   A0A0L8HDN8   A0A2B4S5H5   A0A3M6UN98   D2A3I1   W4ZJK2   A0A2G8K162   W4ZLH1   A0A1W4X6Z1   A0A3B3QM65   A0A3S0ZN14   A0A1Y1N5M7   V3ZE33   A0A2T7P6N6   A0A1S3LD14   A0A1S3LD11   A0A3B4E2P3   A0A369RVY1   B3SBZ0   A0A2R2MMP5   A0A2C9JK78   A0A2R2MT18   A0A2C9JK70   A0A060XHS4   A0A183KTH7   A0A419PK76   G7YJ50   A0A267D9H9   A0A1I8GJ57   K1RJM8   A0A1I8HE72   U4UG54   A0A2T7P6M7   A0A183LAJ4   A0A3P8XPP2   A0A2D0PK34   A0A2D0PK64   A0A2D0PIM8   A0A074ZNX3   A0A1S8WJX6   A0A1L8GPB6   H2YF94   R7VGC6   A0A1X7U4E6   A0A3Q3E168   A0A0R4IHI4   A0A0R4IY79   A0A3N0XG01   A0A2U9BH60   A0A401SWB1   A0A095A169   F6PIN6   A0A430QF48   A0A183NRQ5   W5NAX8   H0X626   A0A177BAD3   I3MF05   A0A1W4Z8M3   A0A1W4Z8M5   M3YZ26   A0A0X3P6T8   A0A183A8Q8   A0A1A6G290   A0A183T112   A0A0X3NTI6   A0A0X3QBN0   A0A0V0J7D3   F6XWP3   G3N1C8   A0A2K6RAT4   A0A3Q3STI9   A0A402FM20   A0A2Y9IYH5   H0V0D2   A0A2K6RAQ5   A0A3Q2HHT5   A0A3B4VGS0   A0A1S3GBV6   A0A2K6MR81   A0A3Q0DG64   A0A3Q4IDQ3   L8IEV2   A0A2U3XK15   A0A452EGB0   G3TQL9   A0A0R3TYZ3  

Pubmed

19121390    29403074    17615350    20566863    9215903    30382153    + More
18362917    19820115    29023486    29240929    28004739    23254933    30042472    18719581    15562597    24755649    22023798    26392545    22992520    23537049    25069045    27762356    23594743    30297745    22246508    20431018    17495919    19393038    25362486    21993624    19892987    26319212    25186727    22751099   

EMBL

NWSH01001830    PCG69979.1    PCG69977.1    PCG69978.1    ODYU01005066    SOQ45577.1    + More
BABH01040386    BABH01040387    RSAL01000037    RVE51194.1    GEDC01005987    JAS31311.1    GEDC01023330    JAS13968.1    GECZ01025168    JAS44601.1    PYGN01000453    PSN46069.1    DS469562    EDO42618.1    DS235030    EEB10716.1    AFYH01005848    AFYH01005849    AFYH01005850    AFYH01005851    AFYH01005852    AFYH01005853    AFYH01005854    AFYH01005855    AFYH01005856    AFYH01005857    KQ418416    KOF87423.1    LSMT01000171    PFX24646.1    RCHS01001119    RMX55115.1    KQ971338    EFA01906.2    AAGJ04100766    AAGJ04100767    AAGJ04100768    AAGJ04100769    AAGJ04100770    AAGJ04100771    MRZV01000992    PIK41736.1    AAGJ04100772    AAGJ04100773    RQTK01000491    RUS78759.1    GEZM01017151    GEZM01017145    JAV90907.1    KB202619    ESO89348.1    PZQS01000006    PVD29061.1    NOWV01000159    RDD38836.1    DS985267    EDV19716.1    FR905415    CDQ79158.1    UZAK01040924    VDP65585.1    NIRI01002318    RJW62475.1    DF143394    GAA52983.1    NIVC01005167    PAA45958.1    JH816168    EKC41830.1    KB632308    ERL92012.1    PVD29059.1    UZAI01000160    VDO49358.1    KL596691    KER28811.1    KV906440    OON14744.1    CM004472    OCT85694.1    AMQN01004546    AMQN01004547    KB293809    ELU15361.1    FO704861    FQ311885    RJVU01075544    ROI16260.1    CP026248    AWP03287.1    BEZZ01000623    GCC34692.1    KL251154    KGB39209.1    AAMC01048030    AAMC01048031    AAMC01048032    AAMC01048033    QMKO01001855    RTG86126.1    UZAL01026724    VDP25180.1    AHAT01014842    AHAT01014843    AHAT01014844    AAQR03061720    AAQR03061721    AAQR03061722    AAQR03061723    AAQR03061724    AAQR03061725    AAQR03061726    AAQR03061727    LWCA01000141    OAF70501.1    AGTP01005611    AGTP01005612    AEYP01001932    GEEE01015646    JAP47579.1    UZAN01040308    VDP69207.1    LZPO01107936    OBS59920.1    UYSU01035690    VDL96547.1    GEEE01020327    JAP42898.1    GEEE01006499    JAP56726.1    GEEE01002213    JAP61012.1    BDOT01000329    GCF57219.1    AAKN02001401    AAKN02001402    JH881365    ELR54718.1    LWLT01000024    UZAE01014939    VDO14848.1   

Proteomes

UP000218220    UP000005204    UP000283053    UP000245037    UP000001593    UP000009046    + More
UP000008672    UP000053454    UP000225706    UP000275408    UP000007266    UP000007110    UP000230750    UP000192223    UP000261540    UP000271974    UP000030746    UP000245119    UP000087266    UP000261440    UP000253843    UP000009022    UP000085678    UP000076420    UP000193380    UP000050789    UP000215902    UP000095280    UP000005408    UP000030742    UP000050790    UP000277204    UP000265140    UP000221080    UP000186698    UP000007875    UP000014760    UP000007879    UP000261660    UP000000437    UP000246464    UP000287033    UP000008143    UP000050791    UP000018468    UP000005225    UP000005215    UP000192224    UP000000715    UP000050740    UP000092124    UP000050788    UP000275846    UP000002280    UP000009136    UP000233200    UP000261640    UP000288954    UP000248482    UP000005447    UP000002281    UP000261420    UP000081671    UP000233180    UP000189706    UP000261580    UP000245341    UP000291000    UP000007646    UP000046398    UP000278807   

PRIDE

H9JXU6   

Pfam

PF08393   DHC_N2        + More
PF12774   AAA_6
PF17852   Dynein_AAA_lid
PF12780   AAA_8
PF17857   AAA_lid_1
PF12777   MT
PF18199   Dynein_C
PF18198   AAA_lid_11
PF03028   Dynein_heavy
PF12781   AAA_9
PF08209   Sgf11

Interpro

IPR042228   Dynein_2_C        + More
IPR035699   AAA_6       
IPR013602   Dynein_heavy_dom-2       
IPR041466   Dynein_AAA5_ext       
IPR027417   P-loop_NTPase       
IPR042222   Dynein_2_N       
IPR026983   DHC_fam       
IPR003593   AAA+_ATPase       
IPR026975   DNAH1       
IPR024317   Dynein_heavy_chain_D4_dom       
IPR041589   DNAH3_AAA_lid_1       
IPR004273   Dynein_heavy_D6_P-loop       
IPR042219   AAA_lid_11_sf       
IPR041228   Dynein_C       
IPR041658   AAA_lid_11       
IPR035706   AAA_9       
IPR024743   Dynein_HC_stalk       
IPR013246   SAGA_su_Sgf11       
IPR013243   SCA7_dom       
IPR016024   ARM-type_fold       

SUPFAM

SSF52540   SSF52540        + More
SSF48371   SSF48371       

Gene 3D

1.20.140.100     3.20.180.20     1.10.8.720    

ProteinModelPortal

A0A2A4JDQ9   A0A2A4JD05   A0A2A4JE46   A0A2H1VXK0   H9JXU6   A0A3S2M4I0   + More
A0A1B6E076   A0A1B6CKQ5   A0A1B6F3E5   A0A2P8YP94   A7S0X9   E0VBG0   H3BFH9   A0A0L8HDN8   A0A2B4S5H5   A0A3M6UN98   D2A3I1   W4ZJK2   A0A2G8K162   W4ZLH1   A0A1W4X6Z1   A0A3B3QM65   A0A3S0ZN14   A0A1Y1N5M7   V3ZE33   A0A2T7P6N6   A0A1S3LD14   A0A1S3LD11   A0A3B4E2P3   A0A369RVY1   B3SBZ0   A0A2R2MMP5   A0A2C9JK78   A0A2R2MT18   A0A2C9JK70   A0A060XHS4   A0A183KTH7   A0A419PK76   G7YJ50   A0A267D9H9   A0A1I8GJ57   K1RJM8   A0A1I8HE72   U4UG54   A0A2T7P6M7   A0A183LAJ4   A0A3P8XPP2   A0A2D0PK34   A0A2D0PK64   A0A2D0PIM8   A0A074ZNX3   A0A1S8WJX6   A0A1L8GPB6   H2YF94   R7VGC6   A0A1X7U4E6   A0A3Q3E168   A0A0R4IHI4   A0A0R4IY79   A0A3N0XG01   A0A2U9BH60   A0A401SWB1   A0A095A169   F6PIN6   A0A430QF48   A0A183NRQ5   W5NAX8   H0X626   A0A177BAD3   I3MF05   A0A1W4Z8M3   A0A1W4Z8M5   M3YZ26   A0A0X3P6T8   A0A183A8Q8   A0A1A6G290   A0A183T112   A0A0X3NTI6   A0A0X3QBN0   A0A0V0J7D3   F6XWP3   G3N1C8   A0A2K6RAT4   A0A3Q3STI9   A0A402FM20   A0A2Y9IYH5   H0V0D2   A0A2K6RAQ5   A0A3Q2HHT5   A0A3B4VGS0   A0A1S3GBV6   A0A2K6MR81   A0A3Q0DG64   A0A3Q4IDQ3   L8IEV2   A0A2U3XK15   A0A452EGB0   G3TQL9   A0A0R3TYZ3  

PDB

5NUG     E-value=3.73705e-19,     Score=231

KEGG

101737254    no KO assigned | (RefSeq) uncharacterized LOC101737254

GO

GO:0003341   GO:0003777   GO:0016887   GO:0005858   GO:0005524   GO:0045503   GO:0007018   GO:0030286   GO:0051959   GO:0008569   GO:0045505   GO:0005930   GO:0000124   GO:0071819   GO:0003713   GO:0008270   GO:0016578   GO:0045893   GO:0016021   GO:0030317   GO:0036159   GO:0036156   GO:0007288   GO:0036126   GO:0060294   GO:0003351  

PANTHER

PTHR10676   PTHR10676:SF358  

Subcellular location

Nucleus  

Length:

287

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06173

Exp number, first 60 AAs:

0

Total prob of N-in:

0.06671

outside

1  -  287

 

 

Pi

323.368542

Theta

213.24667

Tajima's D

1.636347

CLR

0.014482

CSRT

0.817909104544773

Interpretation

Uncertain