Silkworm Genome Informatics Database

Gene

KWMTBOMO08159

Pre Gene Modal

BGIBMGA014367

Annotation

PREDICTED:_dynein_heavy_chain_1?_axonemal-like_[Papilio_polytes]

Location

Bomo_Chr14(-):237571-246719 View in EpiBrowser

Full name

SAGA-associated factor 11 homolog

Location in the cell

Cytoplasmic Reliability : 1.697 PlasmaMembrane Reliability : 1.023

CDS

ATGGCGGAAGTGTCCCTGCCCCACACCCCCGGAGCCACGCCCCTCTCCATCCTGGGGGACCCGGTGCAGATCAGGACGTGGCAGATGTACGGGCTGCCGCGGGACCCGCTGTCGGTGGAGTCCGCCGTGCTGATGGCGGCGTCGCGGCGCTGGCCCCTCGTCATCGACCCCCAGACGCAGGCCAACAACTGGATCCGAGCCATGGGAAAAATCGAAGGTCTGATAGTGTGCAAGCCGAACGACGCGGACCTGCTGCGCAGCTTCGAGTCCGCGCTGCGCTTCGGGAAGCCGCTGCTGCTGGAGAACGTGGGCCAGGAGCTGGACCCCGCGCTCGATCCCGTCCTCAAGCGTCAGTACTTCCGGCAAGCTGGGCAACTGGTGCTGAAGCTGGGCGAGTCGCTGATACCGTACGCGGCTGGCTTCCGCCTGTACATGACTACGAAGCTGCCTAACCCTGTGTACTCCCCGGACACGTCGGTCAAGGTGCAGGTCGTGAACTTCGCCCTGGTGCCCAGTGGGCTGTCGGAGCAGCTGCTGTCGGTGGTGGTGGCGCAGGAGCGGCCGGCGCTGGAGGAGACCCGCGGCGCGCTGGTGGTGTCGCGCGCGCAGCTGTTCGCGCAGCTGGCCACTATGGGCGCGCGCGTGCTGCACGGGCTGGCCTCCTGCCAGGCGCCCGTCGACGACCTGCAGCTCATCCTCACGCTCGAGGCCATCAAGATCAAGACGGCGGAGATCCTGACGAAGGTGTCGGACATGGAGCGCACCACAGCGGAGGTGGACGCCACGCGCGGCGAGTACACCGGCGTGGCGGCGCGCGGACAGATCCTGTTCTTCTGCGTGGCCGCGCTGGCCGCCGTGGACCCCATGTACCAGTACTCGCTCGACTGGTTCACCGGACTCTTCCTCAAGTCCATGGCGGAGACCGAGCCGAGCGAAGACATCCTGGAGCGCGTGGAGACGATCATCGAGCACTTCACGTTCTCGCTGTACCTGAACGTGTGCCGCAGCCTGTTCGAGCGACACAAGCTGCTGTTCGCCTTCCTGCTCACCGCCAGGATCCTGCTCGACGCAGGCGTCATCAGGACCCACGAATACAACTTCTTGATTAATGGTGCTTCATCCCAAGAAGCTTCCGTACCCGAAGGCACTGGACTCACAGCTGGACGCCTTCCAGAAGATCCTTGTGTTGAAGTGTATCCGGCCCGACAAAATGATCCCGGGTCTGCAGCGTGTCGGATGGTGCAGGAATACGTGTCGGCGGCCCGGGGGGCGCGGTACGTGGAGGCGCGGGGCGGGGGAGGGCGCGCCGGGCTGGCCGCGCTGCTGGCCGACTCCTCCCCGCGCGCCCCCCTCGTGCTGGTGCTGTCCTCGGGCACTGACCCGGCCGCCGATTTGATGCAGTTCGCTGACAAGATGAAGATGGGCAAACGGTTCGAGAGCATCTCCCTGGGCCAGGGTCAGGGCCCCATCGCGGAAAACATGATCAGACTGGGCTGCGACTTTGGCAACTGGGTCTTCCTGCAGAACTGTCACCTGTCGCCCTCGTGGATGCCAGCGCTGGAGCTCCTGGTGGAACAACTCCAGGCTGAGAATGTGCACAAAGACTTCCGCCTGTGGCTCACCTCCACACCCTCGCCGCATTTCCCGGTATCGTTATTGCAGAATGGATACAAGATGACGATAGAACCTCCGCGGGGGGTGAAAGCGAACCTGCTGAAGGCTTACACGAACCAGATCCCGGACTTCGCAGACTTCTTTGAGTCGGATGAACCTAAAGTTCCCCAATTTAAGGTTTACTAA

Protein

MAEVSLPHTPGATPLSILGDPVQIRTWQMYGLPRDPLSVESAVLMAASRRWPLVIDPQTQANNWIRAMGKIEGLIVCKPNDADLLRSFESALRFGKPLLLENVGQELDPALDPVLKRQYFRQAGQLVLKLGESLIPYAAGFRLYMTTKLPNPVYSPDTSVKVQVVNFALVPSGLSEQLLSVVVAQERPALEETRGALVVSRAQLFAQLATMGARVLHGLASCQAPVDDLQLILTLEAIKIKTAEILTKVSDMERTTAEVDATRGEYTGVAARGQILFFCVAALAAVDPMYQYSLDWFTGLFLKSMAETEPSEDILERVETIIEHFTFSLYLNVCRSLFERHKLLFAFLLTARILLDAGVIRTHEYNFLINGASSQEASVPEGTGLTAGRLPEDPCVEVYPARQNDPGSAACRMVQEYVSAARGARYVEARGGGGRAGLAALLADSSPRAPLVLVLSSGTDPAADLMQFADKMKMGKRFESISLGQGQGPIAENMIRLGCDFGNWVFLQNCHLSPSWMPALELLVEQLQAENVHKDFRLWLTSTPSPHFPVSLLQNGYKMTIEPPRGVKANLLKAYTNQIPDFADFFESDEPKVPQFKVY

Description

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.

Subunit

Component of some SAGA transcription coactivator-HAT complexes. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).

Similarity

Belongs to the SGF11 family.

Uniprot

A0A3Q2Y7B3 G3VAS5 V3ZE33 R7VGC6 A0A210QDN3 K1RJM8 + More
A0A2R2MMP5 A0A0F8CHK5 G4LX05 A0A1W4Z8M5 A0A1W4Z8M3 A0A3Q2LP38 A0A3S0ZN14 A0A183QCJ7 A0A0L0HV21 K7FV12

Pubmed

21709235 23254933 28812685 22992520 25835551 22253936 + More
19892987 17381049

EMBL

AEFK01097765 KB202619 ESO89348.1 AMQN01004546 AMQN01004547 KB293809 + More
ELU15361.1 NEDP02004067 OWF46845.1 JH816168 EKC41830.1 KQ042005 KKF19598.1 CABG01000035 CCD59439.1 RQTK01000491 RUS78759.1 KQ257450 KND05191.1 AGCU01056634 AGCU01056635 AGCU01056636 AGCU01056637 AGCU01056638 AGCU01056639 AGCU01056640 AGCU01056641 AGCU01056642 AGCU01056643

Proteomes

UP000264820 UP000007648 UP000030746 UP000014760 UP000242188 UP000005408 + More
UP000085678 UP000008854 UP000192224 UP000002281 UP000271974 UP000050792 UP000053201 UP000007267

Pfam

PF18198   AAA_lid_11        + More
PF03028   Dynein_heavy
PF18199   Dynein_C
PF12781   AAA_9
PF12777   MT
PF12780   AAA_8
PF17852   Dynein_AAA_lid
PF17857   AAA_lid_1
PF08393   DHC_N2
PF12774   AAA_6
PF08209   Sgf11

Interpro

IPR041228   Dynein_C        + More
IPR041658   AAA_lid_11
IPR026983   DHC_fam
IPR042219   AAA_lid_11_sf
IPR004273   Dynein_heavy_D6_P-loop
IPR026975   DNAH1
IPR035706   AAA_9
IPR024743   Dynein_HC_stalk
IPR041466   Dynein_AAA5_ext
IPR013602   Dynein_heavy_dom-2
IPR035699   AAA_6
IPR042228   Dynein_2_C
IPR042222   Dynein_2_N
IPR041589   DNAH3_AAA_lid_1
IPR024317   Dynein_heavy_chain_D4_dom
IPR027417   P-loop_NTPase
IPR003593   AAA+_ATPase
IPR013246   SAGA_su_Sgf11
IPR013243   SCA7_dom

SUPFAM

SSF52540 SSF52540

Gene 3D

1.10.8.720 1.20.140.100 3.20.180.20

ProteinModelPortal

A0A3Q2Y7B3 G3VAS5 V3ZE33 R7VGC6 A0A210QDN3 K1RJM8 + More
A0A2R2MMP5 A0A0F8CHK5 G4LX05 A0A1W4Z8M5 A0A1W4Z8M3 A0A3Q2LP38 A0A3S0ZN14 A0A183QCJ7 A0A0L0HV21 K7FV12

PDB

4RH7 E-value=3.73154e-48, Score=485

KEGG

101744900 K10408 dynein heavy chain, axonemal | (RefSeq) dynein heavy chain 3, axonemal

GO

GO:0016887 GO:0003341 GO:0005858 GO:0003777 GO:0005524 GO:0000124 GO:0071819 GO:0003713 GO:0008270 GO:0016578 GO:0045893 GO:0016021 GO:0007018 GO:0030286 GO:0016791 GO:0005515 GO:0005634 GO:0030145 GO:0006412 GO:0016876 GO:0043039

PANTHER

PTHR10676:SF358 PTHR10676

Subcellular location

Nucleus

Length:

599

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.227170000000001

Exp number, first 60 AAs:

0.00111

Total prob of N-in:

0.00795

outside

1 - 599

Pi

203.932013

Theta

191.459957

Tajima's D

0.87438

CLR

0.02152

CSRT

0.625868706564672

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics