Gene

KWMTBOMO08141  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001085

Annotation

PREDICTED:_transient_receptor_potential-gamma_protein_[Bombyx_mori]

Location

Bomo_Chr13(-):17500270-17517839      View in EpiBrowser

Full name

Transient receptor potential-gamma protein      

Alternative Name

Transient receptor potential cation channel gamma

Location in the cell

PlasmaMembrane   Reliability : 3.028

CDS

ATGCTGTTGCAACAGCTGAGCAAAAGCGGCGCCTCCGAGATGTCCGGCGGCAGTGGCGGCGGCGGCTCCAGTGCTGACGGGCGGCGTCCCTCCACCTGCCGCGTGGACATGGGCGCGCTGCTGGCGTCCGAGCCGCGCCCGCTCGACAGCAAGGTTAAGCGGCACAGCATCCACGGGATGACGGAAGAAGAAAATGTGGTTCGACCACATCAGGAGATGGCCGTGCTGTCTTTGGAGGAGAAGAAGTACCTGCTGGGCGTGGAGCGAGGAGACGTGGCGGGGACGCGGCGCGTGCTGCAGCGGGCCCGCGACACCGGACACATCAACGTCGACTGTGTGGACCCGCTCGGACGCAGCGCGCTGCTCATGGCCATTGACAACGAGAACCTCGAGATGGTGGAGCTGCTCCTCGAGTTCGGCGTGGAGACCCGCGACGCACTGCTGCACGCCATCTCCGAGGAGTTCGTCGAGGCCGTGGAGGCCCTGCTCGACCACGAGGAGCGGACCAGGAAGCCCGGCGAACCGAACAGTTGGGAGGCGCTTCCGCCGGAGACGGCCACGTTTACGTCTGACATCACGCCGCTGATCCTGGCGGCGCACCGGGACAGCTACGAGATCATCAAGCTGCTGCTGGACCGCGGCGCGCAGCTGCCCGAGCCGCACGACGTGCGCTGCGGCTGCGACGACTGCGTGCGCTCCCGCCGCGAGGACTCGCTGCGACACTCCCGCTCCAGGATCAACGCGTACCGCGCGCTCGCCTCCCCTTCGCTCATCGCCCTATCCTCCAAGGACCCCATTTTAACCGCTTTCGAGCTGTCGTGGGAGCTGCGCCGGTTGTCCGCATTGGAACATGAGTTCAAAACGGAATACCAGGAGCTCCGCGTTCAGTGTCAGGAGTTCGCGACTGCACTGTTGGATCACACGCGGACGTCTAATGAACTTCAGATCCTGCTGAATCACGAGAAGGGTGCTTCACCTCAGGCACCGCTCACTGAACCAGGCGCTCCCGAGCGGATGCGCTTGTCGCGGCTCAAGCTTGCCATCAAGTTGCGACAAAAGAAGTTCGTGGCGCACCCGAACGTGCAGCAGCTGCTGGCGTCGATCTGGTACGAGAGCGTGCCCGGGTTCCGCCGCAAGAACATGCTGCTGCAGGCGGCGGAGATGGTGCGGATCGGCGCCATGTTCCCGCTCTACTCGCTCGCCTACATCGCGGCGCCGCACTCCGCCGTCGGACGCACGCTCAGGAAGCCCTTCATCAAATTCCTCTGCCACTCCGCCAGTTACTTTATGTTTCTATTTCTGTTGATCCTGGCGTCGCAGCGCATCGAGACGGCGCCGGGCGGGCTGCTGTGGGACGTCTCCCACGACGAGCCGCTCTCCCGGCGCGGCTCCATGCCCTCCATAGTCGAGTGGCTCATACTCGCCTGGGTCAGCGGCTTAATCTGGAGCGAAGTGAAGCAGCTGTGGGACATGGGGCTGAGAGAGTACGTACATGACATGTGGAACGTCATCGACTTCGTCACCAACTCGCTGTACGTGGCCACCGTGGCGCTCAGGATCGTCTCGCACTACCAGGTTCGTCGCGAGATGGCGATGGGCCTGCAGTGGAACCAACCTCGCGAGAAGTGGGACGCTTGGGACCCGATGCTGCTCTCCGAGGGGCTGTTCTCGGCCGCCAACATCTTCAGCAGTCTCAAGTTGGTGTACATCTTCAGCGTGAACCCTCACCTCGGTCCGTTGCAGGTGTCGCTGAGTCGGATGGTGTTGGACATCCTCAAGTTTTTTGTCTTGGACATACTCGTCATATTTGCGTTCTCATGCGGGCTAAACCAGTTGTTGTGGTACTACGCGGACATGGAGAAGAAGCGCTGCACGGTGGGCACCGCGCTCACGCCCAACGGCACCCTGCCCGACCCGGACGCCTGTGTCGTCTGGAGACGGTTTGCTAATTTGTTCGAGACAATGCAGACGCTGTTCTGGGCTGCGTTCGGGCTGGTGGACTTGGATTCGTTCGAGCTCGACGGGATCAAGATCTTCACGCGGTTCTGGGGGATGCTCATGTTCGGCACGTACGCCGTCATCAACGTCATCGTGCTGCTCAACTTGCTCATCGCCATGATGAACCACTCCTATCAGCTGATATCCGAGCGTGCAGATGTGGAATGGAAGTTCGCCCGCAGCAAGCTGTGGATCAGCTACTTTGAGGAGGGTGGAACTGCGCCCCCGCCCTTCAACGTGCTGCCCTCGCCCAAGTCCCTGCTGTACGCCTGGCGGTGGCTGCAGCGCCGGCTCTGTGGGCACGCCCGCGCCAAGCGAGAACATATGCGGACTATTAGGAGAAAGGTGAAGCAAGCCAATGAGAGAGACTTTCGATATCAGGCTATAATGCGGAACCTGGTGCGTCGCTACGTGACGGTCCAGCAGCGGCGCGCGGAGAGCGGCGGCGTCACCGAGGACGACGTCAACGAGATCAAGCAGGACGTCTCCGCCTTCCGCTGCGAGCTCGTCGAGATCCTGCGCAACTCCGGGATGAACACCTCCACAGCCAACGCGGGAGCTCCCGGCGGCGGAGGCGGCAAAAAGAATCGTCAGAAGGAGCGACGCCTCATGAAGGGATTCAACATAGCTCCGGGCGGGTCCCTGGCCCCCGTGGACGAGTTCATGTCGCCCGTGTCCTGGCTGCAGCACGACCACGGCGTGCCGCACTACTCGCTGTCCACGCTGCTCGGGCCGCGCCTGCGAGCCTCCCAGTCCAGCCTCAGCGACGGACCCGGCGCCGGGATGAGTGCGTCGCGTCGCAAGCCGCAGCACAAGCGTCGCTGGGGCACAATCATCGACGCCGCTCGGGCGGCCCGTGTGTCTCGACTCATCGGCCGGTCGCGCTCTGAGGACTCTGTCTGCGATCACGCGCGGCAGTCGCCAAGCGGTAGCGAGCCTTCGGAGTCGGGCAGCGACTCGCAGCGCAGTCCGGAGCGGACGGGATCTCGGAGTGGACCCTTGCATCCGTTGACGGCACTGGCGGCCCTCAAGCGGAAGCGAAAGAAATTCTCGGATTCCCGGCGGCCCGAAGCCACGGTCCGGCCCGTTCCGGCGCCTGAGAGTCTGCAGCGCGCCAGTTCGGTGCCGGCTCGCGTGCCCCCCGCCGCCCCGCCCCGCGCCCCTCCGCCGCCCGCCGTGTCGCCCTCCACCACCGCCGAGAGCGTGGCCGCGCGCGGAGGCAGCCGGGAGCCGCTGCTGGCCAGCCTCGACGACGAAGCGCACAAGCGGGACGGCTGCGGCCAGTGCGGGTACGAGTCGGGGCCGCAGGGCGGCGGGGAGGCGGGGGGCGGGGCGGGCGAGGCGGAGGGCGCGTGCGGGCGGTGCGCGGCGCTGGCGCGGCTGGCGGGCGTGACGCCGCTGGCGGGCCACGCGCCGCACCACTCCGCGGGCTGGCTCTAG

Protein

MLLQQLSKSGASEMSGGSGGGGSSADGRRPSTCRVDMGALLASEPRPLDSKVKRHSIHGMTEEENVVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDNENLEMVELLLEFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRFANLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYAVINVIVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGHARAKREHMRTIRRKVKQANERDFRYQAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVEILRNSGMNTSTANAGAPGGGGGKKNRQKERRLMKGFNIAPGGSLAPVDEFMSPVSWLQHDHGVPHYSLSTLLGPRLRASQSSLSDGPGAGMSASRRKPQHKRRWGTIIDAARAARVSRLIGRSRSEDSVCDHARQSPSGSEPSESGSDSQRSPERTGSRSGPLHPLTALAALKRKRKKFSDSRRPEATVRPVPAPESLQRASSVPARVPPAAPPRAPPPPAVSPSTTAESVAARGGSREPLLASLDDEAHKRDGCGQCGYESGPQGGGEAGGGAGEAEGACGRCAALARLAGVTPLAGHAPHHSAGWL

Description

A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction (By similarity). Forms a regulated cation channel when heteromultimerized with trpl.

Subunit

Interacts preferentially with trpl and interacts to a lower extent with trp.

Similarity

Belongs to the transient receptor (TC 1.A.4) family.
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.

Keywords

ANK repeat   Calcium   Calcium channel   Calcium transport   Complete proteome   Ion channel   Ion transport   Membrane   Reference proteome   Repeat   Sensory transduction   Transmembrane   Transmembrane helix   Transport   Vision  

Feature

chain  Transient receptor potential-gamma protein

Uniprot

H9IV05   A0A212EVK1   A0A2H1WAA9   A0A2A4J9Y4   A0A2W1BXK2   A0A182RRP8   + More
A0A182WHD9   A0A1S4F9E4   A0A182TJL8   A0A1S4GYA0   A0A182L0E3   A0A182PAQ8   A0A182X110   A0A195F2N6   A0A182IC15   A0A182USM7   A0A182NES6   A0A195BR92   A0A0L7KX81   A0A158P1R4   A0A3L8D875   A0A182QJA4   A0A182Y9Z8   E2BGT4   Q17B94   A0A195DC69   A0A182F5L0   A0A088AV64   A0A2M3YXM0   A0A2M4CSL6   A0A067RHQ7   Q7Q4K2   A0A182K9S5   A0A2A3ER74   A0A2M3YXM2   A0A2M4CSW9   A0A2M4CSG3   B7YZW4   A0A2M3ZZU4   A0A2M4BA84   D0QWH5   B4G7Q9   A0A3B0JBF9   A0A034WJC1   U5ENB5   A0A1I8NXJ4   A0A1I8MKX1   A0A0M4EDQ7   A0A384TJQ6   A0A1B0BV64   A0A0L0C5Y3   A0A0R1DV77   B4P9C4   A0A0J9TPI4   A0A0J9R2R7   B3MKM4   Q9VJJ7   A0A1W4VJZ0   A0A1W4VK61   A0A0Q5VXN4   B3NNI2   B4KKT8   A0A0P8XX94   Q29LQ7   A0A0R3NTR5   B4LVK6   A0A1W4VY66   B4NLT7   T1H8K7   A0A0L7RKN9   A0A0M8ZWD1   B4JZ78   A0A0C9R3K2   Q5YJT9   A0A151WQR9   A0A0C9QGE7   B3G505   K7IZ88   E0VCF7   A0A0J7NYX8   A0A026W1F3   E2AZK2   A0A2J7PZ76   A0A1B0GFN2   A0A154NZ64   A0A226E7F5   E9GZL1   A0A0P6HFY0   A0A164TG31   A0A0P6AAK5   A0A0P6GJB5   A0A0P5DNR9   A0A0P5ZY57   A0A0N7ZKT9   A0A059XPJ5   A0A1V9Y157   B7PBX3   A0A336MW87   A0A336M9W2  

Pubmed

19121390    22118469    28756777    12364791    20966253    26227816    + More
21347285    30249741    25244985    20798317    17510324    24845553    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    19859648    17994087    25348373    25315136    26108605    17550304    22936249    18057021    10896160    15632085    16319060    19191929    20075255    20566863    24508170    21292972    28327890   

EMBL

BABH01000036    BABH01000037    BABH01000038    AGBW02012175    OWR45522.1    ODYU01007315    + More
SOQ49990.1    NWSH01002346    PCG68478.1    KZ149891    PZC79051.1    AAAB01008964    KQ981855    KYN34835.1    APCN01000771    KQ976418    KYM89481.1    JTDY01004876    KOB67644.1    ADTU01001096    ADTU01001097    ADTU01001098    ADTU01001099    ADTU01001100    ADTU01001101    ADTU01001102    ADTU01001103    ADTU01001104    ADTU01001105    QOIP01000012    RLU16302.1    AXCN02000840    GL448228    EFN85066.1    CH477324    EAT43552.1    KQ980989    KYN10488.1    GGFM01000266    MBW21017.1    GGFL01004091    MBW68269.1    KK852631    KDR19850.1    EAA12444.4    KZ288192    PBC34293.1    GGFM01000262    MBW21013.1    GGFL01004093    MBW68271.1    GGFL01004092    MBW68270.1    AE014134    ACL83036.2    GGFK01000746    MBW34067.1    GGFJ01000823    MBW49964.1    FJ821029    ACN94674.1    CH479180    EDW29330.1    OUUW01000004    SPP79365.1    GAKP01004193    JAC54759.1    GANO01000663    JAB59208.1    CP012523    ALC40022.1    KX249690    AOR81467.1    JXJN01021148    JRES01000842    KNC27808.1    CM000158    KRJ99073.1    EDW90253.2    KRJ99074.1    CM002910    KMY90538.1    KMY90540.1    KMY90537.1    KMY90539.1    CH902620    EDV32537.2    KPU74022.1    KPU74023.1    AJ277967    AJ277968    CH954179    KQS62953.1    EDV56633.2    KQS62954.1    CH933807    EDW11668.2    KPU74021.1    CH379060    EAL33988.3    KRT04378.1    CH940649    EDW64400.2    CH964274    EDW85326.2    ACPB03022385    KQ414572    KOC71316.1    KQ435850    KOX70909.1    CH916379    EDV94187.1    GBYB01002525    JAG72292.1    AY387857    AAR26327.1    KQ982819    KYQ50204.1    GBYB01002524    JAG72291.1    EU649776    ACD69414.1    AAZO01001036    DS235053    EEB11063.1    LBMM01000754    KMQ97565.1    KK107488    EZA49892.1    GL444248    EFN61135.1    NEVH01020337    PNF21643.1    CCAG010018206    KQ434778    KZC04354.1    LNIX01000006    OXA52821.1    GL732578    EFX75016.1    GDIQ01019517    JAN75220.1    LRGB01001801    KZS10426.1    GDIP01033238    JAM70477.1    GDIQ01042893    JAN51844.1    GDIP01153419    JAJ69983.1    GDIQ01156296    GDIP01038044    JAK95429.1    JAM65671.1    GDIP01235625    JAI87776.1    KJ572528    AIA22827.1    MNPL01001084    OQR79469.1    ABJB010218724    ABJB010332204    ABJB010546725    ABJB011014079    DS679906    EEC04095.1    UFQT01002971    SSX34380.1    UFQT01000733    SSX26810.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000075900    UP000075920    UP000075902    + More
UP000075882    UP000075885    UP000076407    UP000078541    UP000075840    UP000075903    UP000075884    UP000078540    UP000037510    UP000005205    UP000279307    UP000075886    UP000076408    UP000008237    UP000008820    UP000078492    UP000069272    UP000005203    UP000027135    UP000007062    UP000075881    UP000242457    UP000000803    UP000008744    UP000268350    UP000095300    UP000095301    UP000092553    UP000092460    UP000037069    UP000002282    UP000007801    UP000192221    UP000008711    UP000009192    UP000001819    UP000008792    UP000007798    UP000015103    UP000053825    UP000053105    UP000001070    UP000075809    UP000002358    UP000009046    UP000036403    UP000053097    UP000000311    UP000235965    UP000092444    UP000076502    UP000198287    UP000000305    UP000076858    UP000192247    UP000001555   

PRIDE

H9IV05    B7YZW4    Q9VJJ7   

Pfam

PF08344   TRP_2        + More
PF00520   Ion_trans
PF12796   Ank_2
PF00023   Ank
PF00005   ABC_tran
PF00664   ABC_membrane

Interpro

IPR020683   Ankyrin_rpt-contain_dom        + More
IPR036770   Ankyrin_rpt-contain_sf       
IPR005821   Ion_trans_dom       
IPR013555   TRP_dom       
IPR002153   TRPC_channel       
IPR002110   Ankyrin_rpt       
IPR003439   ABC_transporter-like       
IPR017871   ABC_transporter_CS       
IPR011527   ABC1_TM_dom       
IPR027417   P-loop_NTPase       
IPR036640   ABC1_TM_sf       
IPR003593   AAA+_ATPase       

SUPFAM

SSF48403   SSF48403        + More
SSF90123   SSF90123       
SSF52540   SSF52540       

Gene 3D

1.25.40.20     1.20.1560.10    

CDD

cd00204  ANK

ProteinModelPortal

H9IV05   A0A212EVK1   A0A2H1WAA9   A0A2A4J9Y4   A0A2W1BXK2   A0A182RRP8   + More
A0A182WHD9   A0A1S4F9E4   A0A182TJL8   A0A1S4GYA0   A0A182L0E3   A0A182PAQ8   A0A182X110   A0A195F2N6   A0A182IC15   A0A182USM7   A0A182NES6   A0A195BR92   A0A0L7KX81   A0A158P1R4   A0A3L8D875   A0A182QJA4   A0A182Y9Z8   E2BGT4   Q17B94   A0A195DC69   A0A182F5L0   A0A088AV64   A0A2M3YXM0   A0A2M4CSL6   A0A067RHQ7   Q7Q4K2   A0A182K9S5   A0A2A3ER74   A0A2M3YXM2   A0A2M4CSW9   A0A2M4CSG3   B7YZW4   A0A2M3ZZU4   A0A2M4BA84   D0QWH5   B4G7Q9   A0A3B0JBF9   A0A034WJC1   U5ENB5   A0A1I8NXJ4   A0A1I8MKX1   A0A0M4EDQ7   A0A384TJQ6   A0A1B0BV64   A0A0L0C5Y3   A0A0R1DV77   B4P9C4   A0A0J9TPI4   A0A0J9R2R7   B3MKM4   Q9VJJ7   A0A1W4VJZ0   A0A1W4VK61   A0A0Q5VXN4   B3NNI2   B4KKT8   A0A0P8XX94   Q29LQ7   A0A0R3NTR5   B4LVK6   A0A1W4VY66   B4NLT7   T1H8K7   A0A0L7RKN9   A0A0M8ZWD1   B4JZ78   A0A0C9R3K2   Q5YJT9   A0A151WQR9   A0A0C9QGE7   B3G505   K7IZ88   E0VCF7   A0A0J7NYX8   A0A026W1F3   E2AZK2   A0A2J7PZ76   A0A1B0GFN2   A0A154NZ64   A0A226E7F5   E9GZL1   A0A0P6HFY0   A0A164TG31   A0A0P6AAK5   A0A0P6GJB5   A0A0P5DNR9   A0A0P5ZY57   A0A0N7ZKT9   A0A059XPJ5   A0A1V9Y157   B7PBX3   A0A336MW87   A0A336M9W2  

PDB

5Z96     E-value=0,     Score=1787

KEGG

101736324    K04967 transient receptor potential cation channel subfamily C member 4 | (RefSeq) transient recepto

PATHWAY

04745    Phototransduction - fly - Bombyx mori (domestic silkworm)

GO

GO:0005262   GO:0016021   GO:0042626   GO:0005524   GO:0006811   GO:0016020   GO:0070588   GO:0051480   GO:0015279   GO:0070679   GO:0005887   GO:0006828   GO:0034703   GO:0005261   GO:0006812   GO:0007628   GO:0043025   GO:0009416   GO:0050908   GO:1990635   GO:0050884   GO:0006816   GO:0008381   GO:0016028   GO:0016740   GO:0005515   GO:0005216   GO:0015914   GO:0006412   GO:0016876   GO:0043039   GO:0055085  

PANTHER

PTHR10117  

Subcellular location

Membrane  

Length:

1145

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

130.89921

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00796

outside

1  -  388

TMhelix

389  -  411

inside

412  -  417

TMhelix

418  -  440

outside

441  -  499

TMhelix

500  -  522

inside

523  -  549

TMhelix

550  -  572

outside

573  -  593

TMhelix

594  -  616

inside

617  -  681

TMhelix

682  -  704

outside

705  -  1145

 

 

Pi

1.430578

Theta

5.058776

Tajima's D

-1.949945

CLR

629.851816

CSRT

0.0138993050347483

Interpretation

Possibly Positive selection