Gene

KWMTBOMO08134

Pre Gene Modal

BGIBMGA001074

Annotation

PREDICTED:_probable_phospholipid-transporting_ATPase_IA_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr13(+):17331320-17365268      View in EpiBrowser

Full name

Phospholipid-transporting ATPase      

Location in the cell

PlasmaMembrane   Reliability : 4.729

CDS

ATGGGTCTAAACGATGTCGACATGGCGTTAGCTTTGAGAGAGTACGTGGTGAGCTTCTTGCAGGAGCACAACATTATGGCGCCTTTCTCCAGGTTCTATAGGGCCATGGTGCTCAAAATGAACCAGCATGAAGATGAAGCAACTACGTCAGGTATCACCGACGGTGCCACATCCGATCAGCAAAACCGTGTCATTTTCGTCAACAGACCGCAGCCCCAGAAGTTCGTCTCGAACAGGATCTCTACTGCTAAATACAGCGTGCCGTCCTTCGTTCCCTTATTCCTGTTCGAGCAGTTCCGTCGGTATTCCAACTGCTTCTTCCTGTTGATAGCCCTGCTGCAGCAGATCCCTGACGTGTCGCCGACGGGACGGTGGACAACCCTCACTCCTCTCATACTCATACTGAGCGTTAGCGCCATCAAGGAGATTGTTGAAGATTTTAAGCGGCACCGAGCGGACGACGAGACCAACCGCAGGCTGGTGGAGGTGCTGCGGGAGCGGCGCTGGGTCGCCATACGATGGGAGCATCTACAGATCGGCGACATCTGCAAAGTGCTCAACAACCAGTTCTTCCCAGCCGACCTGGTGCTGCTGGCCTCTAGCGAGCCCCAGGGCATATCCTTCATAGAGACCAGCAACCTGGACGGAGAGACCAACCTGAAGATCCGGCAGGCGCAGCCCGACACGGCCCGCCTGGACGCCGCCCCCGCCCTGGCGGACTTCCGCGCCACCGTGCAGTGCGAGCCGCCCAACCGACATCTATACGAATTCAATGGATTGCTAAAGGAGGCCAATGTCAAGACGCTGCCTCTGGGCTTGGACCAGATGCTCCTCCGGGGGGCGATGCTGCGGAACACGGCCTGGGTGCACGGCGTGGTGGTGTACACGGGACACGAAACTAAACTCATGAAGAATTCTACTAAAGCCCCGTTGAAGCGCTCATCGATCGACCGCCAGACCAACACCCACATCTTGATGCTGTTCATCATCCTCCTGGCGCTGTCGCTGCTCAGCGCCGGCTTCAACGAGTTCTGGATGCGGAACCACAATGACTGGTATATCGGCCTCGAAGAGGCGCAGAACGCGCACTTCGGGTTCAACTTCCTGACGTTCCTGATCCTGTACAACAACCTCATACCGATATCGCTGCAGGTCACCGCCGAGATAGTTCGCTTCTTCCAGGCCAAGTTCATCTCCATGGACAGCGAGATGTACGACCCGGCCAGCGACACGGCGGCCATGGCGCGGACCTCCAACCTCAACGAGGAGCTGGGCATGGTGCGCTACGTGTTCAGCGACAAGACCGGCACCCTCACGCAGAACGTCATGGTCTTCCACAAGTGCACCATCGCAGAGGTGATCTACAGCCGGCCGGGGCCCACGGAGCGGCTGGAGGACACGCCGCTGTACCAGAACCTGACGCGGGAGCACCCCACGGCGCCCGTCATCCGCGAGTTCCTCATCATGCTGGCCATCTGCCACACCGTCATCCCCGAGACCAAGGGGGACACCGTGGACTACCACGCCGCTTCCCCCGACGAGCGCGCGCTGGTGACGGGCGCCGCGGCCTTCGGCTTCTCGTTCTGCACGCGCACGCCCAGCCACGTGCACGTGCGCGCGCTGGGGGACACGCTGCGCTACCAGCTGCTGCACGTGCTCGACTTCACCTCCGCCAGGAAGCGCATGTCCGTCATCGTGCGCACGCCGGAAGGGACCATCAAGCTGTACTGCAAGGGCGCGGACAGCGTGATCTACAGCCGGCTGTCCGGCGGAGACAGCGCGCCCTTCGCGGCGGCCACCCTGGCGCACCTGGAGCACTTCGCCGCGGAGGGGCTCCGGACCCTCGTGTTCGCCGTCGCCGACATCCCCGAGCAGGTCTACCAGGACTGGTCCAACACCTACCACAAGGCGAGCATCGCGATACAGGACCGCGAGCAGAAGATCGAGGAAGCTGCCGATCTCGTAGAGAACAACCTGAGGCTGCTCGGAGCCACTGCCATTGAAGACAAGCTGCAGGACGGCGTGCCGGAGACCATCGCCGCGCTCCTGAAGGCCAACATCAACGTGTGGGTGCTCACGGGAGACAAGCAGGAGACCGCCATCAACATCGCGCACTCCGCGCGGCTCATCCACACCGCCATGCCGCTGCTCATACTCAACGAGGACAGCCTCGACGGCACCCGGGAGTCCATGTCGCGCCACGCCATAGACTTCGGAGACAACCTCCGGAAGCAGAACGACGTGGCGCTCGTCATCGACGGAAAGAGCCTCAAGTACGCGATGGGCTGCGACCTGAAGAAGGACTTCCTGGACCTGTGCATATCCTGCAAGGTGGTGGTGTGCTGCAGGGTGTCGCCCATACAGAAGGCCGAGGTGGTGGAGCTGGTGTCGGGCGCCACGGGGGCGGTGACGCTGGCCATCGGCGACGGAGCCAACGACGTGGCCATGATCCAGCGCGCGTCCGTCGGCGTCGGCATCTCCGGCGTCGAGGGGCTGCAGGCCGTCTGCGCCTCCGACTACAGCATCGCGCAGTTCCGTTTCCTGCTCCGCCTGCTGCTGGTGCACGGAGCCTGGAACTACTCGCGAATCAGCAAACTCATTCTGTATTCATTCTACAAAAACATCTGTCTGTACGTCATCGAACTGTGGTTCGCCATATACTCTGCTTGGTCGGGGCAGATCCTGTTCGAGCGGTGGACCATCGGCTTCTACAACGTTATCTTCACTGCGCTGCCACCCTTCGCCATCGGACTCTTCGACAAGCTGTGCTCACCGGAGATCATGCTCAGGCACCCCATCCTGTACATCCCGTCGCAACAAGGGCTGCTGTTCAACGTGCGCGTGTTCTGGGTGTGGGCGGTCAACGCGCTGCTGCACTCCGTGCTGCTGTTCTGGCTGCCCGTGGCGCTCGCCGACCACCACGTGCTGTGGTCCTCGGGCAAGGACGGCGGCTACCTGGTGCTGGGGAACCTGGTCTACACCTACGTGGTTCTGACCGTGTGTCTCAAAGCCGGGCTGGCCACGCACTCGTGGACGTGGGTCACGCACGTCTCCATATGGGGGTCCTTAGCTCTTTGGCTGCTATTCTTACTTATATACAGTAACATATACCCAACGATTCTGATCGGAGCCGTGATGCTGGGCATGGACCGGATGGTGTTCGGCTCCCTGGTCTTCTGGTTCGGCCTCATCCTCATCCCGATAGCGACCCTCATACCGGACCTCGTCGTCACCGTCGTGCGCAACTCCGCCTTCAAATCCGCCACCGAGGCCGTGCGGGAGAGCGAGCTGAAGCAGCGCGCGCCGCCCGCCCTGCTGGCCCAGCCGCGACACTCCCTCACGGAGACGGCGCGGCTGCTGCAGAACGTTCGCAGCGTGTTCACTCGGCGCTCCACCTCGCGGGCCGCCGTCGAGCTAGAGCTCTCGCATGGATTCGCTTTCTCGCAAGAGGAGGGCGGGAGTGTGTCCCAGGCGGACGTGGTCCGAGTGTACGACACAAGGCAGCCGAGACCGGAGCACTCTTGA

Protein

MGLNDVDMALALREYVVSFLQEHNIMAPFSRFYRAMVLKMNQHEDEATTSGITDGATSDQQNRVIFVNRPQPQKFVSNRISTAKYSVPSFVPLFLFEQFRRYSNCFFLLIALLQQIPDVSPTGRWTTLTPLILILSVSAIKEIVEDFKRHRADDETNRRLVEVLRERRWVAIRWEHLQIGDICKVLNNQFFPADLVLLASSEPQGISFIETSNLDGETNLKIRQAQPDTARLDAAPALADFRATVQCEPPNRHLYEFNGLLKEANVKTLPLGLDQMLLRGAMLRNTAWVHGVVVYTGHETKLMKNSTKAPLKRSSIDRQTNTHILMLFIILLALSLLSAGFNEFWMRNHNDWYIGLEEAQNAHFGFNFLTFLILYNNLIPISLQVTAEIVRFFQAKFISMDSEMYDPASDTAAMARTSNLNEELGMVRYVFSDKTGTLTQNVMVFHKCTIAEVIYSRPGPTERLEDTPLYQNLTREHPTAPVIREFLIMLAICHTVIPETKGDTVDYHAASPDERALVTGAAAFGFSFCTRTPSHVHVRALGDTLRYQLLHVLDFTSARKRMSVIVRTPEGTIKLYCKGADSVIYSRLSGGDSAPFAAATLAHLEHFAAEGLRTLVFAVADIPEQVYQDWSNTYHKASIAIQDREQKIEEAADLVENNLRLLGATAIEDKLQDGVPETIAALLKANINVWVLTGDKQETAINIAHSARLIHTAMPLLILNEDSLDGTRESMSRHAIDFGDNLRKQNDVALVIDGKSLKYAMGCDLKKDFLDLCISCKVVVCCRVSPIQKAEVVELVSGATGAVTLAIGDGANDVAMIQRASVGVGISGVEGLQAVCASDYSIAQFRFLLRLLLVHGAWNYSRISKLILYSFYKNICLYVIELWFAIYSAWSGQILFERWTIGFYNVIFTALPPFAIGLFDKLCSPEIMLRHPILYIPSQQGLLFNVRVFWVWAVNALLHSVLLFWLPVALADHHVLWSSGKDGGYLVLGNLVYTYVVLTVCLKAGLATHSWTWVTHVSIWGSLALWLLFLLIYSNIYPTILIGAVMLGMDRMVFGSLVFWFGLILIPIATLIPDLVVTVVRNSAFKSATEAVRESELKQRAPPALLAQPRHSLTETARLLQNVRSVFTRRSTSRAAVELELSHGFAFSQEEGGSVSQADVVRVYDTRQPRPEHS

Catalytic Activity

ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Similarity

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.

Feature

chain  Phospholipid-transporting ATPase

Uniprot

H9IUZ4   A0A194RG10   A0A212EVK6   A0A1L8DEL1   U5EWK7   A0A1Q3G3M2   + More
A0A1Q3G3L2   A0A067RBF1   A0A0L0BV56   A0A1L8DE92   A0A1I8P2W8   A0A1I8P2Y5   A0A1B0A519   A0A1I8NB71   A0A1I8NB83   Q17N94   A0A1A9W039   A0A336MCV4   A0A1A9XGU1   A0A336MA04   A0A1B0FNL8   A0A1B0BJF9   A0A1A9V9K6   N6W4Q3   A0A3B0JEZ8   B4KTN7   W8BBM3   W8ARP7   A0A0K8V6W8   A0A0K8VP29   A0A034V3T4   D2A294   A0A0Q5VZ68   A0A0Q9X8V3   A0A0P8YDR8   A0A1Y9IYG1   A0A0Q5VP98   A0A0Q5W0M8   A0A1W4VGI2   A0A0P8Y6Q7   A0A0R1DPX3   A0A1W4VH17   A0A182XC77   A0A0Q5VWW1   A0A1W4VGH7   A0A0Q5VMY5   A0A0R1DQ69   A0A182YK07   Q8T0I4   A0A0J9U0W3   A0A0R1DQU3   A0A1Y1MJW6   A0A0J9RBT3   A0A1Y1MD21   A0A0Q9W2Z2   A0A3L8D697   B7YZF5   A0A026WAN0   A0A0J9RCZ3   B7YZF6   A0A0R3NPB7   A0A151J935   A0A336MAX9   B4MIW7   A0A336ME27   E2A435   A0A195CI92   A0A1W4XFT1   A0A0K8VME7   A0A0K8UV14   A0A1Q3G3K0   A0A195B6B1   A0A0M9A0V8   A0A2M3ZFX1   A0A1Q3G3K8   V9I7B1   F4WL37   V9I9H6   A0A139WIQ2   A0A088AVA3   A0A151WM27   A0A2A3ET72   A0A310SAH7   A0A2M4BBB1   A0A0Q9X8Q2   U4UI06   A0A2M4BB13   A0A2M4CUY1   A0A182FKQ4   A0A0Q5W1W9   Q17N93   A0A2M4A747   A0A154P6V4   A0A0C9QBV8   A0A0Q5VX56   A0A1W4VH26   A0A1Y1MG03   A0A0R1DQ74   A0A1W4V4P7   D0Z766  

EC Number

7.6.2.1

Pubmed

19121390    26354079    22118469    24845553    26108605    25315136    + More
17510324    15632085    17994087    24495485    25348373    18362917    19820115    17550304    25244985    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    28004739    30249741    24508170    20798317    21719571    23537049   

EMBL

BABH01000052    BABH01000053    BABH01000054    KQ460297    KPJ16245.1    AGBW02012175    + More
OWR45528.1    GFDF01009182    JAV04902.1    GANO01001371    JAB58500.1    GFDL01000645    JAV34400.1    GFDL01000655    JAV34390.1    KK852570    KDR21171.1    JRES01001289    KNC23912.1    GFDF01009379    JAV04705.1    CH477201    EAT48160.1    UFQT01000781    SSX27181.1    SSX27182.1    CCAG010015909    JXJN01015380    CM000071    ENO01787.1    OUUW01000001    SPP73870.1    CH933808    EDW09620.2    GAMC01019295    GAMC01019291    JAB87264.1    GAMC01019293    GAMC01019292    JAB87263.1    GDHF01017999    JAI34315.1    GDHF01011677    JAI40637.1    GAKP01022156    GAKP01022155    JAC36797.1    KQ971338    EFA02157.2    CH954179    KQS62750.1    KRG04764.1    CH902619    KPU77080.1    KQS62748.1    KQS62746.1    KPU77083.1    CM000158    KRJ99335.1    KQS62745.1    KQS62743.1    KRJ99336.1    AY069236    AE013599    AAL39381.1    AAM68573.1    CM002911    KMY93480.1    KRJ99342.1    GEZM01034879    JAV83567.1    KMY93482.1    GEZM01034880    GEZM01034874    JAV83573.1    CH940648    KRF79266.1    QOIP01000012    RLU15759.1    ACL83103.1    KK107353    EZA52084.1    KMY93484.1    ACL83109.1    KRT02810.1    KQ979471    KYN21420.1    SSX27180.1    CH963719    EDW72056.2    SSX27179.1    GL436526    EFN71801.1    KQ977720    KYN00428.1    GDHF01012252    JAI40062.1    GDHF01021961    JAI30353.1    GFDL01000662    JAV34383.1    KQ976587    KYM79719.1    KQ435794    KOX73593.1    GGFM01006716    MBW27467.1    GFDL01000661    JAV34384.1    JR036186    AEY56983.1    GL888207    EGI65000.1    JR036187    AEY56984.1    KYB27799.1    KQ982944    KYQ48851.1    KZ288192    PBC34339.1    KQ766603    OAD53651.1    GGFJ01001182    MBW50323.1    KRG04767.1    KB632308    ERL91978.1    GGFJ01001085    MBW50226.1    GGFL01004978    MBW69156.1    KQS62751.1    EAT48161.1    GGFK01003305    MBW36626.1    KQ434827    KZC07665.1    GBYB01011958    JAG81725.1    KQS62747.1    GEZM01034876    JAV83570.1    KRJ99340.1    BT100313    ACZ52625.1   

Proteomes

UP000005204    UP000053240    UP000007151    UP000027135    UP000037069    UP000095300    + More
UP000092445    UP000095301    UP000008820    UP000091820    UP000092443    UP000092444    UP000092460    UP000078200    UP000001819    UP000268350    UP000009192    UP000007266    UP000008711    UP000007801    UP000076407    UP000192221    UP000002282    UP000076408    UP000000803    UP000008792    UP000279307    UP000053097    UP000078492    UP000007798    UP000000311    UP000078542    UP000192223    UP000078540    UP000053105    UP000007755    UP000005203    UP000075809    UP000242457    UP000030742    UP000069272    UP000076502   

PRIDE

H9IUZ4    Q8T0I4    B7YZF5    B7YZF6    D0Z766   

Pfam

PF16212   PhoLip_ATPase_C        + More
PF16209   PhoLip_ATPase_N

Interpro

IPR023214   HAD_sf        + More
IPR036412   HAD-like_sf       
IPR032631   P-type_ATPase_N       
IPR006539   P-type_ATPase_IV       
IPR023299   ATPase_P-typ_cyto_dom_N       
IPR001757   P_typ_ATPase       
IPR008250   ATPase_P-typ_transduc_dom_A_sf       
IPR023298   ATPase_P-typ_TM_dom_sf       
IPR018303   ATPase_P-typ_P_site       
IPR032630   P_typ_ATPase_c       

SUPFAM

SSF81660   SSF81660        + More
SSF81665   SSF81665       
SSF56784   SSF56784       
SSF81653   SSF81653       

Gene 3D

3.40.1110.10     3.40.50.1000    

ProteinModelPortal

H9IUZ4   A0A194RG10   A0A212EVK6   A0A1L8DEL1   U5EWK7   A0A1Q3G3M2   + More
A0A1Q3G3L2   A0A067RBF1   A0A0L0BV56   A0A1L8DE92   A0A1I8P2W8   A0A1I8P2Y5   A0A1B0A519   A0A1I8NB71   A0A1I8NB83   Q17N94   A0A1A9W039   A0A336MCV4   A0A1A9XGU1   A0A336MA04   A0A1B0FNL8   A0A1B0BJF9   A0A1A9V9K6   N6W4Q3   A0A3B0JEZ8   B4KTN7   W8BBM3   W8ARP7   A0A0K8V6W8   A0A0K8VP29   A0A034V3T4   D2A294   A0A0Q5VZ68   A0A0Q9X8V3   A0A0P8YDR8   A0A1Y9IYG1   A0A0Q5VP98   A0A0Q5W0M8   A0A1W4VGI2   A0A0P8Y6Q7   A0A0R1DPX3   A0A1W4VH17   A0A182XC77   A0A0Q5VWW1   A0A1W4VGH7   A0A0Q5VMY5   A0A0R1DQ69   A0A182YK07   Q8T0I4   A0A0J9U0W3   A0A0R1DQU3   A0A1Y1MJW6   A0A0J9RBT3   A0A1Y1MD21   A0A0Q9W2Z2   A0A3L8D697   B7YZF5   A0A026WAN0   A0A0J9RCZ3   B7YZF6   A0A0R3NPB7   A0A151J935   A0A336MAX9   B4MIW7   A0A336ME27   E2A435   A0A195CI92   A0A1W4XFT1   A0A0K8VME7   A0A0K8UV14   A0A1Q3G3K0   A0A195B6B1   A0A0M9A0V8   A0A2M3ZFX1   A0A1Q3G3K8   V9I7B1   F4WL37   V9I9H6   A0A139WIQ2   A0A088AVA3   A0A151WM27   A0A2A3ET72   A0A310SAH7   A0A2M4BBB1   A0A0Q9X8Q2   U4UI06   A0A2M4BB13   A0A2M4CUY1   A0A182FKQ4   A0A0Q5W1W9   Q17N93   A0A2M4A747   A0A154P6V4   A0A0C9QBV8   A0A0Q5VX56   A0A1W4VH26   A0A1Y1MG03   A0A0R1DQ74   A0A1W4V4P7   D0Z766  

PDB

6A69     E-value=2.6922e-14,     Score=196

KEGG

101746988    K14802 phospholipid-transporting ATPase [EC:7.6.2.1] | (RefSeq) probable phospholipid-transporting A

GO

GO:0000287   GO:0016021   GO:0004012   GO:0005524   GO:0005886   GO:0005802   GO:0045332   GO:0005794   GO:0000166   GO:0046872   GO:0015914   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR24092  

Subcellular location

Membrane  

Length:

1174

Number of predicted TMHs:

9

Exp number of AAs in TMHs:

185.15398

Exp number, first 60 AAs:

0.14565

Total prob of N-in:

0.13682

outside

1  -  322

TMhelix

323  -  345

inside

346  -  364

TMhelix

365  -  387

outside

388  -  841

TMhelix

842  -  861

inside

862  -  867

TMhelix

868  -  890

outside

891  -  899

TMhelix

900  -  919

inside

920  -  947

TMhelix

948  -  970

outside

971  -  984

TMhelix

985  -  1007

inside

1008  -  1019

TMhelix

1020  -  1042

outside

1043  -  1056

TMhelix

1057  -  1079

inside

1080  -  1174

 

 

Pi

15.938211

Theta

17.907273

Tajima's D

-0.853523

CLR

1.029669

CSRT

0.16289185540723

Interpretation

Uncertain