SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO08126  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA001068
Annotation
Fumarylacetoacetate_hydrolase_isoform_A_[Operophtera_brumata]
Full name
Fumarylacetoacetate hydrolase domain-containing protein 2      
Location in the cell
Cytoplasmic   Reliability : 2.611
 

Sequence

CDS
ATGAAACTCCTACAGTTTTCTTACAAAAACAGCGATGGAATCCGAGCGGGTTTCTTAGATGGCGATAATGTTGTGGATATCAATAAAGAAGATCCAAAATTACCATCAACGTTAATTGAGCTCCTCAAAACGAATTCCATTTCCAAAGTGAAAAAAATCAGCGCCAAATCACCAGTGCCTTTATCCGGTATCACGCTGAAAGCTCCGGTCCATGGAAATGATAAAGTACTATGCGTGGGATTAAATTACAAAGATCACTGTGAAGAGCAGAAATTGACGCCTCCAGAACTTCCTTTTATATTCAACAAATTTCCTAGTACTGTGGTGGGACCAAACGACACCATCAAGTTAAAAATGGATGTAAGTAAAGCTGTGGTCTGCGAGATAGAACTGACGGTTGTAATCGGGAAGAAAGCCAGTAAAGTAGATTCATCGCATGCCTTTGATTATGTCCTCGGCTACACAATAGCCCAGGATATCGGCGCTACAGACTGGGAGAAGAACAAGAAAATCAGTCAATTGCTGTTGGGTAAAGCAATGGACACCTTCTGCCCAATTGGACCTTGGATAGTTACCAGCGATGAGATCGGAAATCCTCAGAATTTGAATGTAAAGTGCAGCATTAATGGCGTTCAGAAACAGAAGAGTAATACAAACCAATTTATCCACAAAATCCCGGATATTATTGCAAGATTATCAAATGTTATGACTCTTTTGCCAGGAGACATCATTTTGACCGGGACTCCTGGCGGTGTTGGTGTATACAGAAACCCCCCAGAGTTTCTTCAACCCGGTGACGTGATCACGAGTGAAATAGAGAACATTGGTACTTTTGAAACAAGAGTCGAAGAATTTTAA
Protein
MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNSISKVKKISAKSPVPLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF

Summary

Description
May have hydrolase activity.
Cofactor
Ca(2+)
Mg(2+)
Similarity
Belongs to the FAH family.
Keywords
Calcium   Hydrolase   Magnesium   Metal-binding   Acetylation   Complete proteome   Reference proteome  
Feature
chain  Fumarylacetoacetate hydrolase domain-containing protein 2
EC Number
3.-.-.-
EMBL
BABH01000070    NWSH01001435    PCG71237.1    ODYU01004895    SOQ45239.1    KZ149928    + More
PZC77479.1    JTDY01003234    KOB69908.1    GAIX01004016    JAA88544.1    RSAL01000019    RVE52794.1    BABH01035686    DQ311271    ABD36216.1    ODYU01002352    SOQ39735.1    NWSH01000019    PCG80729.1    PCG80727.1    ODYU01000131    SOQ34390.1    AK403436    BAM19701.1    KQ459144    KPJ03612.1    CH477202    EAT48142.1    AJWK01025642    GAPW01002414    JAC11184.1    GFDF01001104    JAV12980.1    GFDF01001103    JAV12981.1    JH816002    EKC38637.1    GEBQ01018730    JAT21247.1    GFDG01003417    JAV15382.1    GECZ01004610    JAS65159.1    DS233329    EDS29440.1    GECU01022497    JAS85209.1    UFQS01000773    UFQT01000773    SSX06780.1    SSX27125.1    SSX06779.1    SSX27124.1    GBHO01022780    GBHO01022778    GBRD01006623    GBRD01006622    JAG20824.1    JAG20826.1    JAG59198.1    KK852941    KDR13529.1    AAAB01008986    EAL38923.3    GEDC01021841    JAS15457.1    APCN01001831    GFFW01002505    JAV42283.1    GDHC01014194    JAQ04435.1    NEDP02005386    OWF41480.1    GFDL01007013    JAV28032.1    ABLF02030307    AXCM01002192    AXCN02001066    KB365080    ELV11525.1    GFDL01007642    JAV27403.1    GFDL01006969    JAV28076.1    BC074365    GAMD01002771    JAA98819.1    AAGW02007409    BT127816    AEE62778.1    AMGL01078866    AAPE02041650    KE161478    EPQ04105.1    GGMR01014456    MBY27075.1    JW870532    AFP03050.1    GGFM01004724    MBW25475.1    AGTP01102139    ADMH02001501    ETN62292.1    GGFK01008523    MBW41844.1    DS235802    EEB17236.1    CYRY02032846    VCX10250.1    CM004470    OCT89956.1    GGFK01008656    MBW41977.1    GGFK01008587    MBW41908.1    MCFN01000251    OXB61816.1    JH000086    EGW04973.1    JH880729    ELR59332.1    GDAI01002214    JAI15389.1    GFXV01004058    MBW15863.1    AEYP01076409    AFYH01183888    RAZU01000234    RLQ64354.1    BDOT01000015    GCF44253.1    KA645988    KA649281    AFP60617.1    BC166933    CU683877    FP101906    LWLT01000009    HAEB01003648    SBQ50175.1    SSX06778.1    SSX27123.1   
Pfam
PF01557   FAA_hydrolase        + More
PF00232   Glyco_hydro_1
PF00096   zf-C2H2
Interpro
IPR011234   Fumarylacetoacetase-like_C        + More
IPR036663   Fumarylacetoacetase_C_sf       
IPR001360   Glyco_hydro_1       
IPR017853   Glycoside_hydrolase_SF       
IPR036236   Znf_C2H2_sf       
IPR013087   Znf_C2H2_type       
SUPFAM
SSF56529   SSF56529        + More
SSF51445   SSF51445       
SSF57667   SSF57667       
Gene 3D
PDB
3QDF     E-value=5.00593e-37,     Score=386

Ontologies

Topology

Length:
285
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.09916
Exp number, first 60 AAs:
0
Total prob of N-in:
0.03478
outside
1  -  285
 
 

Population Genetic Test Statistics

Pi
11.56217
Theta
17.197664
Tajima's D
-0.915879
CLR
16.149706
CSRT
0.152842357882106
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
28556443 LPSTLIELLK 100.00 1e-10
28556443 FPSTVVGPNDTIK 100.00 0.003
28556443 STSELGIGSAK 100.00 0.007
28556443 IPDIIAR 100.00 0.020
28556443 LTPPELPFIFNK 100.00 0.020
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