Gene

KWMTBOMO08126  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001068

Annotation

Fumarylacetoacetate_hydrolase_isoform_A_[Operophtera_brumata]

Location

Bomo_Chr13(+):17113041-17114010      View in EpiBrowser

Full name

Fumarylacetoacetate hydrolase domain-containing protein 2      

Location in the cell

Cytoplasmic   Reliability : 2.611

CDS

ATGAAACTCCTACAGTTTTCTTACAAAAACAGCGATGGAATCCGAGCGGGTTTCTTAGATGGCGATAATGTTGTGGATATCAATAAAGAAGATCCAAAATTACCATCAACGTTAATTGAGCTCCTCAAAACGAATTCCATTTCCAAAGTGAAAAAAATCAGCGCCAAATCACCAGTGCCTTTATCCGGTATCACGCTGAAAGCTCCGGTCCATGGAAATGATAAAGTACTATGCGTGGGATTAAATTACAAAGATCACTGTGAAGAGCAGAAATTGACGCCTCCAGAACTTCCTTTTATATTCAACAAATTTCCTAGTACTGTGGTGGGACCAAACGACACCATCAAGTTAAAAATGGATGTAAGTAAAGCTGTGGTCTGCGAGATAGAACTGACGGTTGTAATCGGGAAGAAAGCCAGTAAAGTAGATTCATCGCATGCCTTTGATTATGTCCTCGGCTACACAATAGCCCAGGATATCGGCGCTACAGACTGGGAGAAGAACAAGAAAATCAGTCAATTGCTGTTGGGTAAAGCAATGGACACCTTCTGCCCAATTGGACCTTGGATAGTTACCAGCGATGAGATCGGAAATCCTCAGAATTTGAATGTAAAGTGCAGCATTAATGGCGTTCAGAAACAGAAGAGTAATACAAACCAATTTATCCACAAAATCCCGGATATTATTGCAAGATTATCAAATGTTATGACTCTTTTGCCAGGAGACATCATTTTGACCGGGACTCCTGGCGGTGTTGGTGTATACAGAAACCCCCCAGAGTTTCTTCAACCCGGTGACGTGATCACGAGTGAAATAGAGAACATTGGTACTTTTGAAACAAGAGTCGAAGAATTTTAA

Protein

MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNSISKVKKISAKSPVPLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF

Description

May have hydrolase activity.

Cofactor

Ca(2+)
Mg(2+)

Similarity

Belongs to the FAH family.

Keywords

Calcium   Hydrolase   Magnesium   Metal-binding   Acetylation   Complete proteome   Reference proteome  

Feature

chain  Fumarylacetoacetate hydrolase domain-containing protein 2

Uniprot

H9IUY8   A0A2A4JGP7   A0A2H1VWM9   A0A2W1BQW5   A0A0L7L322   S4PCS0   + More
A0A3S2NJT7   H9IS36   Q2F601   A0A2H1VFY1   A0A2A4K9I9   A0A2A4K945   A0A2H1V0L4   I4DP61   A0A194QDS5   Q17N03   A0A1B0CS49   A0A023ERA0   A0A1L8E2L4   A0A1L8E2P0   K1QP24   A0A1B6LC38   A0A1L8E9V2   A0A1B6GRW8   B0XIL6   A0A1B6IE47   A0A336L0T5   A0A336KQN9   A0A0A9XLH6   A0A067R380   Q5TMH4   A0A1B6CPP5   A0A182HN30   A0A182VNE1   A0A250YF70   A0A146LA26   A0A1I8PWU6   A0A182LNV2   A0A182WX74   A0A182U545   A0A210PYB4   A0A182KBL7   A0A1Q3FKJ5   A0A1I8MQA1   A0A182YNI4   A0A182PDB0   J9JPT5   A0A182MSH9   A0A182QB46   L8Y998   A0A182MXL1   A0A1Q3FIU4   A0A1Q3FKS1   Q6GLT8   T1DGH7   G1TPZ3   A0A182WEL4   J3JX48   W5PXA6   G1Q7R9   S7MKS3   A0A1S3FGH8   A0A2S2PCF2   V9KVI1   A0A2M3ZAH2   A0A1S3FF86   A0A1S3FEX5   I3NDW8   W5JD71   A0A2M4AM47   E0VV30   A0A1U7Q9F0   A0A3P4PJU0   A0A1L8H1M1   A0A2M4AMK1   A0A2M4AMS7   A0A226N2J6   G3H030   L8IW04   A0A0K8TM05   A0A3Q7VD17   A0A2H8TNV6   M3YCH2   A0A2Y9L439   H3AA15   A0A2Y9HN79   A0A3L7HEG4   A0A2Y9QBB7   A0A402EJ73   T1PDK5   A0A3Q7Q6V4   B2RYW9   A0A384CV90   A0A452R677   A0A3Q7UHT5   A0A0R4IWE1   A0A452FAL7   A0A1A8ESQ4   A0A336KRN5  

EC Number

3.-.-.-

Pubmed

19121390    28756777    26227816    23622113    22651552    26354079    + More
17510324    24945155    22992520    25401762    24845553    12364791    14747013    17210077    28087693    26823975    20966253    28812685    25315136    25244985    23385571    21993624    22516182    20809919    24402279    20920257    23761445    20566863    27762356    21804562    22751099    26369729    9215903    29704459    15489334    23594743   

EMBL

BABH01000070    NWSH01001435    PCG71237.1    ODYU01004895    SOQ45239.1    KZ149928    + More
PZC77479.1    JTDY01003234    KOB69908.1    GAIX01004016    JAA88544.1    RSAL01000019    RVE52794.1    BABH01035686    DQ311271    ABD36216.1    ODYU01002352    SOQ39735.1    NWSH01000019    PCG80729.1    PCG80727.1    ODYU01000131    SOQ34390.1    AK403436    BAM19701.1    KQ459144    KPJ03612.1    CH477202    EAT48142.1    AJWK01025642    GAPW01002414    JAC11184.1    GFDF01001104    JAV12980.1    GFDF01001103    JAV12981.1    JH816002    EKC38637.1    GEBQ01018730    JAT21247.1    GFDG01003417    JAV15382.1    GECZ01004610    JAS65159.1    DS233329    EDS29440.1    GECU01022497    JAS85209.1    UFQS01000773    UFQT01000773    SSX06780.1    SSX27125.1    SSX06779.1    SSX27124.1    GBHO01022780    GBHO01022778    GBRD01006623    GBRD01006622    JAG20824.1    JAG20826.1    JAG59198.1    KK852941    KDR13529.1    AAAB01008986    EAL38923.3    GEDC01021841    JAS15457.1    APCN01001831    GFFW01002505    JAV42283.1    GDHC01014194    JAQ04435.1    NEDP02005386    OWF41480.1    GFDL01007013    JAV28032.1    ABLF02030307    AXCM01002192    AXCN02001066    KB365080    ELV11525.1    GFDL01007642    JAV27403.1    GFDL01006969    JAV28076.1    BC074365    GAMD01002771    JAA98819.1    AAGW02007409    BT127816    AEE62778.1    AMGL01078866    AAPE02041650    KE161478    EPQ04105.1    GGMR01014456    MBY27075.1    JW870532    AFP03050.1    GGFM01004724    MBW25475.1    AGTP01102139    ADMH02001501    ETN62292.1    GGFK01008523    MBW41844.1    DS235802    EEB17236.1    CYRY02032846    VCX10250.1    CM004470    OCT89956.1    GGFK01008656    MBW41977.1    GGFK01008587    MBW41908.1    MCFN01000251    OXB61816.1    JH000086    EGW04973.1    JH880729    ELR59332.1    GDAI01002214    JAI15389.1    GFXV01004058    MBW15863.1    AEYP01076409    AFYH01183888    RAZU01000234    RLQ64354.1    BDOT01000015    GCF44253.1    KA645988    KA649281    AFP60617.1    BC166933    CU683877    FP101906    LWLT01000009    HAEB01003648    SBQ50175.1    SSX06778.1    SSX27123.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000283053    UP000053268    UP000008820    + More
UP000092461    UP000005408    UP000002320    UP000027135    UP000007062    UP000075840    UP000075903    UP000095300    UP000075882    UP000076407    UP000075902    UP000242188    UP000075881    UP000095301    UP000076408    UP000075885    UP000007819    UP000075883    UP000075886    UP000011518    UP000075884    UP000001811    UP000075920    UP000002356    UP000001074    UP000081671    UP000005215    UP000000673    UP000009046    UP000189706    UP000186698    UP000198323    UP000001075    UP000286642    UP000000715    UP000248482    UP000008672    UP000248481    UP000273346    UP000248483    UP000288954    UP000286641    UP000002494    UP000261680    UP000291022    UP000000437    UP000291000   

PRIDE

H9IUY8    H9IS36    Q2F601    Q6GLT8    G3H030    B2RYW9    + More

Pfam

PF01557   FAA_hydrolase        + More
PF00232   Glyco_hydro_1
PF00096   zf-C2H2

Interpro

IPR011234   Fumarylacetoacetase-like_C        + More
IPR036663   Fumarylacetoacetase_C_sf       
IPR001360   Glyco_hydro_1       
IPR017853   Glycoside_hydrolase_SF       
IPR036236   Znf_C2H2_sf       
IPR013087   Znf_C2H2_type       

SUPFAM

SSF56529   SSF56529        + More
SSF51445   SSF51445       
SSF57667   SSF57667       

Gene 3D

3.90.850.10    

ProteinModelPortal

H9IUY8   A0A2A4JGP7   A0A2H1VWM9   A0A2W1BQW5   A0A0L7L322   S4PCS0   + More
A0A3S2NJT7   H9IS36   Q2F601   A0A2H1VFY1   A0A2A4K9I9   A0A2A4K945   A0A2H1V0L4   I4DP61   A0A194QDS5   Q17N03   A0A1B0CS49   A0A023ERA0   A0A1L8E2L4   A0A1L8E2P0   K1QP24   A0A1B6LC38   A0A1L8E9V2   A0A1B6GRW8   B0XIL6   A0A1B6IE47   A0A336L0T5   A0A336KQN9   A0A0A9XLH6   A0A067R380   Q5TMH4   A0A1B6CPP5   A0A182HN30   A0A182VNE1   A0A250YF70   A0A146LA26   A0A1I8PWU6   A0A182LNV2   A0A182WX74   A0A182U545   A0A210PYB4   A0A182KBL7   A0A1Q3FKJ5   A0A1I8MQA1   A0A182YNI4   A0A182PDB0   J9JPT5   A0A182MSH9   A0A182QB46   L8Y998   A0A182MXL1   A0A1Q3FIU4   A0A1Q3FKS1   Q6GLT8   T1DGH7   G1TPZ3   A0A182WEL4   J3JX48   W5PXA6   G1Q7R9   S7MKS3   A0A1S3FGH8   A0A2S2PCF2   V9KVI1   A0A2M3ZAH2   A0A1S3FF86   A0A1S3FEX5   I3NDW8   W5JD71   A0A2M4AM47   E0VV30   A0A1U7Q9F0   A0A3P4PJU0   A0A1L8H1M1   A0A2M4AMK1   A0A2M4AMS7   A0A226N2J6   G3H030   L8IW04   A0A0K8TM05   A0A3Q7VD17   A0A2H8TNV6   M3YCH2   A0A2Y9L439   H3AA15   A0A2Y9HN79   A0A3L7HEG4   A0A2Y9QBB7   A0A402EJ73   T1PDK5   A0A3Q7Q6V4   B2RYW9   A0A384CV90   A0A452R677   A0A3Q7UHT5   A0A0R4IWE1   A0A452FAL7   A0A1A8ESQ4   A0A336KRN5  

PDB

3QDF     E-value=5.00593e-37,     Score=386

KEGG

101736048    no KO assigned | (RefSeq) fumarylacetoacetate hydrolase domain-containing protein 2-like

GO

GO:0003824   GO:0016787   GO:0004553   GO:0005975   GO:0016853   GO:0046872   GO:0008704   GO:0018800   GO:0003676   GO:0008152   GO:0005783   GO:0006457   GO:0051082   GO:0015914   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR10353  

Length:

285

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.09916

Exp number, first 60 AAs:

0

Total prob of N-in:

0.03478

outside

1  -  285

 

 

Pi

11.56217

Theta

17.197664

Tajima's D

-0.915879

CLR

16.149706

CSRT

0.152842357882106

Interpretation

Uncertain