Gene

KWMTBOMO08111  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001100

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_tyrosine-protein_phosphatase_non-receptor_type_11-like_[Bombyx_mori]

Location

Bomo_Chr13(-):16055787-16059096      View in EpiBrowser

Full name

Tyrosine-protein phosphatase non-receptor type      

Location in the cell

Cytoplasmic   Reliability : 2.757

CDS

ATGATAACTCGAAGATGGTTCCACCCCTCGCTGAATGGTGTGGACGCGGAAAAATTGCTCATGGAGTGCGGTCACGATGGGTATTTCCTGGCCAGGCCAAGTTCAAGTAATAAAGGAGATTTCACTCTCTCCGTCCGAAGAGGAAATGAGGTCACTCATATAAAAATTCAGAACAACGGCGAATTTCTCGATCTTTATGGAGGTGAAAAATTTGCTACCCTGTCAGAACTCGTCCAATATTATATGGACAATCAATGCCAGCTAAGAGAAAAAAATGGAAATATAATTAGGTTAAAAACGCCTCTCAACTGTGCAGATCCAACAACCGAACGATGGTACCACGGGCAGCTCACTGCCAAGGAAGCAGAGAGAATGATGATGGAAAACGGAAAAAACGGGTCGTTTCTCGTTCGCGAATCCCAAAGGCAACCTGGCGACTTCGTGTTGTCCGTTCGCACGAGAGATCGAGTTACACATGTGATAATTAGGCGAAAGGACAACAAATATGACGTAGGTGGGGGGCAACAGTTTGACGATCTCGTAAGTCTAATAGAATACTATCGTAGTTTTCCCATGGTCGAGACTACTGGTGAGGAAAACGAGGGACCCATCGAGAGCATGGCCTACAAACAAGGTTTCTGGGAGGAATTCGAAACGTTACAGATGATGGAGAACTTGCAGTTGTTCGACAGAATGGAGGGTTCGAAACCGGAGAATATTAGGAAAAACAGATACAAAAATATTATACCATTCGATCACACGCGTGTTATTTTAAAGGACATCCCCCCTGACGGTCCTCCGGGCTCAGATTACATCAATGCCAACTACATTCGATGTGACAGTATGGATTCCATTTCCGATTCCCAAGAATTCACAGGGAACGGCAGCACTGAAAACGGCAAAGACGGTACGCCGTCGAAAGCTAAAGATAAATCATCGCCTGTTCATACAAGCGTTATCGTAACTGAAGAGCCGGTCAAATCAAGTAAGAAGGTGCACGGCAACGGAACACACAAGCTGCCGGCGTTCGAACCGAGCGTTCTTCGTCCCAACCCGAATTATTTCAATACGACAATACCGAAATCAGCGACCGAAACCGAAAACGGTGTGCCCACTGTACACGTGTACAACAAAACGTACATAGCTACTCAAGGCTGTCTTTCGACAACAATATACCCGTTCTGGTCGATGATATGGCAAGAGGACGTCCGCATCATCATAATGACGACAAAGGAGATCGAGCGCGGGAAGGTCAAATGCGAAAGGTACTGGCCGGACTTGAACAAAACAGAGGTCGTCAAGAAGTACACGATACTTAACGAATTCGAATCCTCCACGCCGGATTATACGCTTCGACGGTTCCTTGTCACGAAAAAAGATGAGACTACAGTGAAGCGGACCATATATCATTTCCATTTCACGGCCTGGCCGGACCATCGTGTTCCCTCAGAGCCCGGTCGCGTGCTCAACATTCTACTGGACGTGAACTACAGGCTACAGCAGATAATGACGGGGACCGATCCTCCGGCGCAGGCGGTCGTATGTGTTCATTGCTCGGCGGGTATAGGTCGGACGGGAACCTTCATAGTCATCGATATGATCTTGGACCAAATAAGAAAGGAAGGGTTCGACTGCGAGATCGACATACATCGCACTGTGCAGATGGTGCGCGACCAAAGGTCCGGTATGGTGCAGAACGAAGCTCAATATAAGTTTATCTACATGGCCGTGTTGGAGTTTATCGAAACGGAGAAGCAAAGGGTAGGTCTCGGGCCGGAGGCGGCACAGGACTCGCCGCGAGCCAGGTCTATGCCCGTACCATTTTTATGA

Protein

MITRRWFHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSVRRGNEVTHIKIQNNGEFLDLYGGEKFATLSELVQYYMDNQCQLREKNGNIIRLKTPLNCADPTTERWYHGQLTAKEAERMMMENGKNGSFLVRESQRQPGDFVLSVRTRDRVTHVIIRRKDNKYDVGGGQQFDDLVSLIEYYRSFPMVETTGEENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCDSMDSISDSQEFTGNGSTENGKDGTPSKAKDKSSPVHTSVIVTEEPVKSSKKVHGNGTHKLPAFEPSVLRPNPNYFNTTIPKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDSPRARSMPVPFL

Catalytic Activity

H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate

Similarity

Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.

Uniprot

H9IV20   A0A2H1WY52   A0A2A4K380   A0A194Q681   A0A194RJU9   A0A0L7LLZ9   + More
A0A212ETM7   A0A1Q3FV42   A0A1Q3FUP0   A0A1Q3FV66   A0A1S4FJQ9   A0A1L8DLN1   A0A1J1HPS2   A0A1J1HV72   A0A195DM14   A0A1I8MWH3   A0A1S4GFJ7   A0A0K8UG39   A0A0A1XPL0   A0A034V7D6   A0A034V5R1   W8BRK0   W8BL49   W8BDZ7   Q5TTR3   A0A2M3ZZK1   A0A2M4BH42   A0A0A1WVB4   A0A0P6DZ20   A0A0R3NZB4   A0A0R3NZM3   A0A452C922   A0A2Y9QLI1   A0A2U4CKF1   A0A452C8W1   A0A2Y9QEG1   A0A2U4CKM6   A0A0V1HZH6   A0A0V1DZC7   A0A1Q3FXY5   A0A1Q3FY24   A0A1J1HR93   A0A1L8DLU8   A0A1Q3FVE6   A0A1Q3FV89   A0A1A9W0Q5   A0A3S2M4Z3   A0A0K8VQ68   A0A0K8VYW7   A0A2A4JVZ2   A0A2A4JVA9   A0A1Q3FY41   A0A1A9YBK0   A0A1B0D637  

EC Number

3.1.3.48

Pubmed

19121390    26354079    26227816    22118469    25315136    12364791    + More
25830018    25348373    24495485    15632085    17994087   

EMBL

BABH01000164    ODYU01011528    SOQ57314.1    NWSH01000210    PCG78378.1    KQ459439    + More
KPJ01043.1    KQ460297    KPJ16226.1    JTDY01000610    KOB76472.1    AGBW02012542    OWR44855.1    GFDL01003723    JAV31322.1    GFDL01003724    JAV31321.1    GFDL01003722    JAV31323.1    GFDF01006807    JAV07277.1    CVRI01000015    CRK90056.1    CRK90057.1    KQ980762    KYN13534.1    AAAB01008859    GDHF01027049    JAI25265.1    GBXI01001512    JAD12780.1    GAKP01021479    JAC37473.1    GAKP01021475    JAC37477.1    GAMC01007072    JAB99483.1    GAMC01007073    JAB99482.1    GAMC01007070    JAB99485.1    EAL40926.4    GGFK01000610    MBW33931.1    GGFJ01003172    MBW52313.1    GBXI01011711    JAD02581.1    GDIQ01070546    JAN24191.1    CH379064    KRT06376.1    KRT06377.1    JYDS01000310    KRZ15474.1    JYDR01000169    KRY66434.1    GFDL01002679    JAV32366.1    GFDL01002632    JAV32413.1    CRK90058.1    GFDF01006750    JAV07334.1    GFDL01003527    JAV31518.1    GFDL01003526    JAV31519.1    RSAL01000032    RVE51530.1    GDHF01011326    JAI40988.1    GDHF01008247    JAI44067.1    NWSH01000575    PCG75552.1    PCG75554.1    GFDL01002643    JAV32402.1    AJVK01025699    AJVK01025700    AJVK01025701    AJVK01025702   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000037510    UP000007151    + More
UP000183832    UP000078492    UP000095301    UP000007062    UP000001819    UP000261681    UP000248483    UP000245320    UP000054805    UP000054632    UP000091820    UP000283053    UP000092443    UP000092462   

PRIDE

H9IV20   

Pfam

PF00017   SH2        + More
PF00102   Y_phosphatase

Interpro

IPR000242   PTPase_domain        + More
IPR000387   TYR_PHOSPHATASE_dom       
IPR036860   SH2_dom_sf       
IPR016130   Tyr_Pase_AS       
IPR003595   Tyr_Pase_cat       
IPR000980   SH2       
IPR029021   Prot-tyrosine_phosphatase-like       
IPR012152   Tyr_Pase_non-rcpt_typ-6/11       

SUPFAM

SSF52799   SSF52799        + More
SSF55550   SSF55550       

Gene 3D

3.30.505.10     3.90.190.10    

ProteinModelPortal

H9IV20   A0A2H1WY52   A0A2A4K380   A0A194Q681   A0A194RJU9   A0A0L7LLZ9   + More
A0A212ETM7   A0A1Q3FV42   A0A1Q3FUP0   A0A1Q3FV66   A0A1S4FJQ9   A0A1L8DLN1   A0A1J1HPS2   A0A1J1HV72   A0A195DM14   A0A1I8MWH3   A0A1S4GFJ7   A0A0K8UG39   A0A0A1XPL0   A0A034V7D6   A0A034V5R1   W8BRK0   W8BL49   W8BDZ7   Q5TTR3   A0A2M3ZZK1   A0A2M4BH42   A0A0A1WVB4   A0A0P6DZ20   A0A0R3NZB4   A0A0R3NZM3   A0A452C922   A0A2Y9QLI1   A0A2U4CKF1   A0A452C8W1   A0A2Y9QEG1   A0A2U4CKM6   A0A0V1HZH6   A0A0V1DZC7   A0A1Q3FXY5   A0A1Q3FY24   A0A1J1HR93   A0A1L8DLU8   A0A1Q3FVE6   A0A1Q3FV89   A0A1A9W0Q5   A0A3S2M4Z3   A0A0K8VQ68   A0A0K8VYW7   A0A2A4JVZ2   A0A2A4JVA9   A0A1Q3FY41   A0A1A9YBK0   A0A1B0D637  

PDB

6MDD     E-value=1.56351e-97,     Score=911

KEGG

101737822    K07293 tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48] | (RefSeq) tyrosine-protein p

PATHWAY

04013    MAPK signaling pathway - fly - Bombyx mori (domestic silkworm)

GO

GO:0004725   GO:0005737   GO:0016311   GO:0016791   GO:0006470   GO:0030132   GO:0015914   GO:0046872   GO:0006412   GO:0016876   GO:0043039  

Subcellular location

Cytoplasm  

Length:

609

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.05924

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00114

outside

1  -  609

 

 

Pi

21.987536

Theta

4.482022

Tajima's D

0.502643

CLR

1.500357

CSRT

0.543922803859807

Interpretation

Uncertain