Gene

KWMTBOMO08097  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001107

Annotation

DNA_supercoiling_factor_[Bombyx_mori]

Location

Bomo_Chr13(-):15933578-15937286      View in EpiBrowser

Full name

Calumenin-B       + More
Calumenin      

Alternative Name

Crocalbin
IEF SSP 9302

Location in the cell

Cytoplasmic   Reliability : 2.085

CDS

ATGTACAAACCCGAGGACGGCGAGGACGAGGAGGAACCCGACTGGGTCAAGCAGGAGAGAGAACAGTTTACTGGATACAGAGATACGAATAAGGACGGGTTCATGGACGAGCACGAGGTGAAGGACTGGATCGCGCCGCCGGAGTTCGACCACGCGGAGGCCGAGGCGCGCCACCTCGTGTTCGAGGCCGACGCCGACGCAGACGAGAAGCTCACCAAGGCCGAGATCATCGACAAGTACGATCTCTTCGTCGGCTCGCAGGCCACCGACTTCGGCGAAGCACTCGCCAGACACGACGAATTTTAA

Protein

MYKPEDGEDEEEPDWVKQEREQFTGYRDTNKDGFMDEHEVKDWIAPPEFDHAEAEARHLVFEADADADEKLTKAEIIDKYDLFVGSQATDFGEALARHDEF

Description

Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase ggcx. Binds 7 calcium ions with a low affinity (By similarity).
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).

Subunit

Interacts with ggcx.
Interacts with GGCX.

Similarity

Belongs to the CREC family.

Keywords

Calcium   Complete proteome   Endoplasmic reticulum   Glycoprotein   Golgi apparatus   Membrane   Metal-binding   Reference proteome   Repeat   Sarcoplasmic reticulum   Secreted   Signal   Acetylation   Alternative splicing   Direct protein sequencing   Phosphoprotein   Polymorphism  

Feature

chain  Calumenin-B
splice variant  In isoform 15.
sequence variant  In dbSNP:rs2290228.

Uniprot

G9FL14   Q93136   A0A194RF50   A0A194Q7Q8   A0A2A4JW54   A0A2H1WQL7   + More
S4PSB2   A0A212EX33   A0A3S2PK98   A0A182U3Q0   A0A182XFN2   A0A182LN58   Q7QDS4   A0A182HX52   A0A182MFS9   A0A182VP64   A0A182K9R5   A0A182SIW5   A0A182YE68   A0A182P1A0   A0A182R8X5   A0A0T6B3A3   E0VBH5   A0A182NVC3   A0A182Q3Y8   A0A182W8B6   A0A182FLY7   A0A2M4BWV7   D2A169   A0A2M4BUB1   W5JBJ4   A0A084VJI4   A0A182J1Q4   A0A2J7Q139   A0A023EQT3   A0A2J7Q112   A0A2M4AWK1   Q0IEY6   V9PBR3   A0A1S4EKS1   B0W572   Q207I9   A0A1Q3FMF4   A0A1Y1K6Q0   A0A1Q3FML7   A0A1B6JUC7   A0A154PNC9   A0A1B6HBB1   A0A1S3ML90   B5X4E0   T1JLL4   A0A1B0DFV8   A0A1W7R9T9   A0A060XGU7   A0A0C9RE82   A0A0L7QY92   A0A3B4FM91   A0A3Q2WW28   A0A195B6F8   F4WSS6   A0A2J8QT00   H0Y875   A0A3Q3LJU3   I3KCN5   A0A195FPW8   A0A151XD84   A0A1B6E6K0   A0A158NH09   O43852-15   A0A2R2MS28   A0A250YAM7   A0A1B6MN73   G3V004   A0A067RB55   A0A3B3IHZ0   A0A3P9LP03   A0A3B3D771   A0A3P9I4F0   A0A3P9LNU5   A0A151J1Y5   O96051   A0A0C9R530   B3KQK3   A0A2G9S1D1   A0A3P9AHZ4   G3PH64   C1BTZ9   A0A3P8R1F8   A0A3P9CWS2   G3PH67   A0A3P8UT21   A0A3Q1H6T2   C3ZK54   Q8IRH7   M3ZYR1   A0A2U9BW86   A0A315US90   A0A3B4YA47   A0A3B4UIB0   A0A3B5MUN6  

Pubmed

19121390    7797553    26354079    23622113    22118469    20966253    + More
12364791    14747013    17210077    25244985    20566863    18362917    19820115    20920257    23761445    24438588    24945155    26483478    17510324    28004739    20433749    24755649    21719571    12853948    21269460    23186163    25944712    25186727    21347285    9675259    9598325    14702039    15489334    12665801    10222138    12643545    17081065    16964243    18691976    19159218    19139490    20068231    24275569    26091039    28087693    19468303    21183079    23806337    24845553    17554307    29451363    9774687    16303743    25069045    24487278    18563158    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    23542700    29703783   

EMBL

BABH01000173    JN171664    AEO79985.1    D49948    BAA08704.1    KQ460297    + More
KPJ16212.1    KQ459439    KPJ01030.1    NWSH01000457    PCG76267.1    ODYU01009967    SOQ54734.1    GAIX01014008    JAA78552.1    AGBW02011840    OWR46049.1    RSAL01000009    RVE53846.1    AAAB01008849    EAA07240.3    APCN01005137    AXCM01001696    LJIG01016193    KRT81335.1    DS235030    EEB10731.1    AXCN02002295    GGFJ01008067    MBW57208.1    KQ971338    EFA02623.1    GGFJ01007390    MBW56531.1    ADMH02001606    ETN61842.1    ATLV01013581    KE524868    KFB38128.1    AXCP01007332    NEVH01019960    PNF22279.1    JXUM01101857    JXUM01101858    GAPW01002619    JAC10979.1    PNF22278.1    GGFK01011856    MBW45177.1    CH477461    EAT40554.1    KC282397    AGX25154.1    DS231841    EDS34819.1    DQ407909    ABD65581.1    GFDL01006320    JAV28725.1    GEZM01091041    GEZM01091040    JAV57132.1    GFDL01006319    JAV28726.1    GECU01033021    GECU01027847    GECU01004891    GECU01004505    JAS74685.1    JAS79859.1    JAT02816.1    JAT03202.1    KQ434996    KZC13237.1    GECU01035715    GECU01035055    GECU01034243    GECU01024945    GECU01021570    GECU01021011    GECU01005931    JAS71991.1    JAS72651.1    JAS73463.1    JAS82761.1    JAS86136.1    JAS86695.1    JAT01776.1    BT045909    JH432114    AJVK01059049    GFAH01000485    JAV47904.1    FR905356    CDQ78671.1    GBYB01011462    JAG81229.1    KQ414693    KOC63572.1    KQ976574    KYM80103.1    GL888327    EGI62733.1    NBAG03000017    PNI99406.1    AC024952    AERX01005254    KQ981387    KYN41979.1    KQ982294    KYQ58334.1    GEDC01031670    GEDC01029371    GEDC01017660    GEDC01004022    GEDC01003728    GEDC01001923    JAS05628.1    JAS07927.1    JAS19638.1    JAS33276.1    JAS33570.1    JAS35375.1    ADTU01015424    U67280    AF013759    AF345637    HM002604    HM002605    HM002606    HM002607    HM002608    HM002609    HM002610    HM002611    HM002612    HM002613    HM002614    HM002615    HM002616    AK056338    CR541835    CH471070    BC013383    AF257659    GFFW01004096    JAV40692.1    GEBQ01002658    JAT37319.1    AC044807    KK852761    KDR16997.1    KQ980447    KYN16001.1    AB011261    BAA34049.1    GBYB01011424    JAG81191.1    AK075089    BAG52065.1    KV927880    PIO33959.1    BT078078    ACO12502.1    GG666636    EEN46953.1    AE014296    JQ663526    AAN11468.1    AFI26260.1    CP026252    AWP08547.1    NHOQ01002850    PWA14215.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000218220    UP000007151    UP000283053    + More
UP000075902    UP000076407    UP000075882    UP000007062    UP000075840    UP000075883    UP000075903    UP000075881    UP000075901    UP000076408    UP000075885    UP000075900    UP000009046    UP000075884    UP000075886    UP000075920    UP000069272    UP000007266    UP000000673    UP000030765    UP000075880    UP000235965    UP000069940    UP000008820    UP000079169    UP000002320    UP000076502    UP000087266    UP000092462    UP000193380    UP000053825    UP000261460    UP000264840    UP000078540    UP000007755    UP000005640    UP000261640    UP000005207    UP000078541    UP000075809    UP000005205    UP000085678    UP000000589    UP000027135    UP000001038    UP000265180    UP000261560    UP000265200    UP000078492    UP000265140    UP000007635    UP000265100    UP000265160    UP000265120    UP000265040    UP000001554    UP000000803    UP000002852    UP000246464    UP000261360    UP000261420    UP000261380   

PRIDE

G9FL14    Q93136    B5X4E0    H0Y875    I3KCN5    O43852    + More
G3V004    O96051    Q8IRH7   

Pfam

PF13499   EF-hand_7        + More
PF13202   EF-hand_5
PF01157   Ribosomal_L21e
PF13833   EF-hand_8

Interpro

IPR018247   EF_Hand_1_Ca_BS        + More
IPR002048   EF_hand_dom       
IPR011992   EF-hand-dom_pair       
IPR027239   Calumenin       
IPR008991   Translation_prot_SH3-like_sf       
IPR001147   Ribosomal_L21e       
IPR036948   Ribosomal_L21_sf       

SUPFAM

SSF47473   SSF47473        + More
SSF50104   SSF50104       

Gene 3D

2.30.30.70    

ProteinModelPortal

G9FL14   Q93136   A0A194RF50   A0A194Q7Q8   A0A2A4JW54   A0A2H1WQL7   + More
S4PSB2   A0A212EX33   A0A3S2PK98   A0A182U3Q0   A0A182XFN2   A0A182LN58   Q7QDS4   A0A182HX52   A0A182MFS9   A0A182VP64   A0A182K9R5   A0A182SIW5   A0A182YE68   A0A182P1A0   A0A182R8X5   A0A0T6B3A3   E0VBH5   A0A182NVC3   A0A182Q3Y8   A0A182W8B6   A0A182FLY7   A0A2M4BWV7   D2A169   A0A2M4BUB1   W5JBJ4   A0A084VJI4   A0A182J1Q4   A0A2J7Q139   A0A023EQT3   A0A2J7Q112   A0A2M4AWK1   Q0IEY6   V9PBR3   A0A1S4EKS1   B0W572   Q207I9   A0A1Q3FMF4   A0A1Y1K6Q0   A0A1Q3FML7   A0A1B6JUC7   A0A154PNC9   A0A1B6HBB1   A0A1S3ML90   B5X4E0   T1JLL4   A0A1B0DFV8   A0A1W7R9T9   A0A060XGU7   A0A0C9RE82   A0A0L7QY92   A0A3B4FM91   A0A3Q2WW28   A0A195B6F8   F4WSS6   A0A2J8QT00   H0Y875   A0A3Q3LJU3   I3KCN5   A0A195FPW8   A0A151XD84   A0A1B6E6K0   A0A158NH09   O43852-15   A0A2R2MS28   A0A250YAM7   A0A1B6MN73   G3V004   A0A067RB55   A0A3B3IHZ0   A0A3P9LP03   A0A3B3D771   A0A3P9I4F0   A0A3P9LNU5   A0A151J1Y5   O96051   A0A0C9R530   B3KQK3   A0A2G9S1D1   A0A3P9AHZ4   G3PH64   C1BTZ9   A0A3P8R1F8   A0A3P9CWS2   G3PH67   A0A3P8UT21   A0A3Q1H6T2   C3ZK54   Q8IRH7   M3ZYR1   A0A2U9BW86   A0A315US90   A0A3B4YA47   A0A3B4UIB0   A0A3B5MUN6  

KEGG

692759    no KO assigned | (RefSeq) scf; DNA supercoiling factor

GO

GO:0005509   GO:0005783   GO:0005789   GO:0005576   GO:0005794   GO:0033018   GO:0042470   GO:0003735   GO:0006412   GO:0005840   GO:0016021   GO:0043687   GO:0005788   GO:0016020   GO:0044267   GO:0045893   GO:0009047   GO:0006325   GO:0012505   GO:0005700   GO:0016853  

PANTHER

PTHR10827:SF76  

Subcellular location

Endoplasmic reticulum membrane  
Golgi apparatus  
Secreted  
Melanosome  
Sarcoplasmic reticulum lumen  

Length:

101

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.19375

outside

1  -  101

 

 

Pi

29.780104

Theta

25.208707

Tajima's D

0.528031

CLR

0.036736

CSRT

0.524673766311684

Interpretation

Uncertain