Gene

KWMTBOMO08081  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001048

Annotation

PREDICTED:_low-density_lipoprotein_receptor-related_protein_6_[Bombyx_mori]

Location

Bomo_Chr13(+):15150310-15154828      View in EpiBrowser

Full name

Low-density lipoprotein receptor-related protein      

Location in the cell

Cytoplasmic   Reliability : 1.19 PlasmaMembrane   Reliability : 1.12

CDS

ATGACAAAGCGTCGGAGAATACTTTACGCGGACAAAATCATTCAGAAAGTCGTTCATGTGTTTTGTTTGTTGATGTTTTTACAGTTGAAAGGTCACCATACCACACCTAGCAATCCTATACTCCTTTATTCGACTGCTTTAGATATACGTATGGTAAATACATCGAGATTAACTAGAATCACTACAATCGCTAAGGACTTGGAGCAAGGCACAGCGGTTGACTTCCATTATAGAAAGAATTTAATATGCTGGTCTGATCAGAAGCCCGAACTTATACAGTGTATGAATTATAATGAAACTTATACAGGTGAAAAGTTTAAAATAGTATCAGAAGGCCTAGTGACTCCAACTGGTATAGCTATAGATTGGTACACAGACAAGTTGTACTGGACAGATGGAGAAACAAACAAAATCGAAGTTATTAGTATAGTACAAAAATATAGGAAGGTTCTATTTTGGTCTGAGGTTGATTTGGCTCGAGCTATCGCTGTTGTTCCAGAGGATGGATTAATGTTCTGGACTGATTGGGGTGAAATACCAAAAATAGAAAGGGCGGGTATGAATGGTGATCCAGCCACGCGCAAAGTTATAGTCAGAGACAACATATTCTGGCCCAATGGAATAACAGTGGATTACAACAATAGCCTAATATATTGGGTCGATGCCAAACTCCAATTTGTAGACGTCATAGATTTTAATGGCGAAAAACGTAAAAGGGTTGTCAAGGGTGGATTGGTTTATCCTTTTGCTTTGACTTTTTCTAACGATAAATTGTATTGGACCGATTGGCAAAATTGGTCTATTTATACTTGGGATATAGCAGCTAACGGTCCTAAAATAAAGGAGTTGATAAAATCGCATCCCGTTCCTGCAGACATCAAAGTGTATGATGAAAGTAGACAAATTATATCGGCTGAAGATTATCCGTGTAAAAAGAATAATGCTGGTTGTTCACACTTGTGCCTTTTATCACCCGATCCCCCAGGTTACAATTGCGCGTGCCCAACGGGCGTGAAGCTGAGGGAAAATAGCAGCACGACTTGTTACGACAGCCCCCAGATGCTGCTGGTGGTCGCCCAGCGCTCCACGATATCCAAGATATCGCTGGACTCGCCAGATTTCACTCCATATACGTTGCCCTTGAAGGATTTGAAACGGACCCTGACTGTTGACTTCGACCCTAAAACGGAATATATTTACTGGGCTGATGGTTTGGTATGCACTAACTATGTTACATTCGTATAA

Protein

MTKRRRILYADKIIQKVVHVFCLLMFLQLKGHHTTPSNPILLYSTALDIRMVNTSRLTRITTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKVYDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQMLLVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLVCTNYVTFV

Similarity

Belongs to the LDLR family.

Uniprot

H9IUW8   A0A2W1C4L5   A0A194RHB0   A0A2H1W340   A0A194Q7P7   A0A2A4JDU2   + More
A0A1E1WPK0   A0A212ERU9   A0A0L7LIC0   A0A1B6H952   A0A1B6KTB0   A0A1B6HTI9   A0A1V1FQJ8   A0A088AJF0   A0A2A3E6R5   A0A0M8ZSK8   A0A0A9YIG5   A0A151I365   A0A151JTX8   A0A1B6BXD2   F4X5W2   E2B7S9   A0A158NMF6   A0A0L7R7D2   A0A3L8DL26   E2A3U3   A0A2P8YCY9   A0A232ETC2   K7IYY2   A0A2H8TD26   A0A2S2P0K4   A0A2R7WEE8   A0A146LXD3   A0A1Y1M0S0   A0A224X518   A0A2S2QFY6   E0VCE3   A0A026WGG7   A0A195CCJ2   D2A038   A0A2J7QGD9   A0A067QSV8   A0A1I8MEY3   A0A0L0C8A9   A0A0P5YV12   W8BVL4   A0A0P5X248   A0A151WS83   Q6AWJ8   A0A1B0G7N5   Q28ZT5   A0A1A9ZGJ1   A0A1A9V5E9   A0A1I8PWX5   B4HQJ0   A0A0P5Y2D5   Q95V09   B3NRK7   A0A0J9RBX9   A0A3B0JQS3   B4GGT4   A0A1W4V4L1   A0A1A9XP08   A0A3B0JHZ3   Q9NHE9   A1Z9D7   B4P4H3   A0A0P5BA92   A0A0K8UBG2   A0A151J3V0   A0A0P5X114   A0A0P5BJ23   A0A0P5VEQ9   A0A0P5B9K8   A0A0P5VIK7   A0A0A1WEM1   A0A0P5AF92   A0A0P4YNR5   A0A0P5A807   A0A0P5V056   A0A0P4YGB1   A0A0P5U743   A0A0P5WWU6   A0A0N8A2S8   A0A0P5UPS1   A0A0P6IMF6   A0A0N8D0B5   A0A0P6G760   A0A0P5YXR7   A0A0P5DHF3   A0A0P5BCB8   A0A0P5D9M4   B3MGY8   B4MCL5   A0A0T6AX35   A0A1A9WIS8   B4MS00   B4JVN1   E9FT42   B4KML3  

Pubmed

19121390    28756777    26354079    22118469    26227816    28410430    + More
25401762    21719571    20798317    21347285    30249741    29403074    28648823    20075255    26823975    28004739    20566863    24508170    18362917    19820115    24845553    25315136    26108605    24495485    15632085    17994087    23185243    11029006    18057021    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    25830018    21292972   

EMBL

BABH01000258    BABH01000259    BABH01000260    BABH01000261    KZ149891    PZC79083.1    + More
KQ460397    KPJ15321.1    ODYU01005992    SOQ47443.1    KQ459439    KPJ01020.1    NWSH01001864    PCG69878.1    GDQN01002217    JAT88837.1    AGBW02012947    OWR44189.1    JTDY01000991    KOB75177.1    GECU01036547    JAS71159.1    GEBQ01025284    JAT14693.1    GECU01029720    JAS77986.1    FX985390    BAX07403.1    KZ288349    PBC27447.1    KQ435916    KOX68763.1    GBHO01010742    JAG32862.1    KQ976507    KYM82832.1    KQ981847    KYN34995.1    GEDC01031356    GEDC01010247    JAS05942.1    JAS27051.1    GL888742    EGI58202.1    GL446209    EFN88222.1    ADTU01020439    KQ414642    KOC66743.1    QOIP01000007    RLU21016.1    GL436500    EFN71887.1    PYGN01000696    PSN42118.1    NNAY01002297    OXU21592.1    GFXV01000185    MBW11990.1    GGMR01010384    MBY23003.1    KK854704    PTY18034.1    GDHC01007322    JAQ11307.1    GEZM01046160    JAV77476.1    GFTR01008831    JAW07595.1    GGMS01007462    MBY76665.1    DS235053    EEB11049.1    KK107238    EZA54791.1    KQ977957    KYM98435.1    KQ971338    EFA02463.2    NEVH01014378    PNF27659.1    KK853320    KDR08547.1    JRES01000762    KNC28501.1    GDIP01052988    JAM50727.1    GAMC01009214    GAMC01009213    JAB97341.1    GDIP01078826    JAM24889.1    KQ982782    KYQ50720.1    BT015250    AAT94479.1    CCAG010016887    CM000071    EAL25528.2    KRT02342.1    KRT02343.1    CH480816    EDW47725.1    GDIP01064977    JAM38738.1    AY005815    AAF91072.1    CH954179    EDV56159.1    CM002911    KMY93508.1    OUUW01000001    SPP75011.1    CH479183    EDW35704.1    SPP75010.1    AF223365    AAF28358.1    AE013599    BT133102    AAF58373.2    AEX98022.1    CM000158    EDW90612.2    GDIP01188116    JAJ35286.1    GDHF01028396    JAI23918.1    KQ980246    KYN17111.1    GDIP01078825    JAM24890.1    GDIP01188115    JAJ35287.1    GDIP01101021    JAM02694.1    GDIP01188114    JAJ35288.1    GDIP01101020    JAM02695.1    GBXI01016965    JAC97326.1    GDIP01202862    JAJ20540.1    GDIP01224812    JAI98589.1    GDIP01202861    JAJ20541.1    GDIP01106617    JAL97097.1    GDIP01227957    GDIP01035636    LRGB01001937    JAI95444.1    KZS09955.1    GDIP01118673    JAL85041.1    GDIP01081328    JAM22387.1    GDIP01188113    JAJ35289.1    GDIP01110018    JAL93696.1    GDIQ01002771    JAN91966.1    GDIP01081327    JAM22388.1    GDIQ01056240    JAN38497.1    GDIP01051778    JAM51937.1    GDIP01156167    JAJ67235.1    GDIP01190711    JAJ32691.1    GDIP01164563    JAJ58839.1    CH902619    EDV37906.1    KPU77098.1    KPU77099.1    CH940659    EDW71403.1    LJIG01022599    KRT79721.1    CH963850    EDW74889.2    CH916375    EDV98499.1    GL732524    EFX89307.1    CH933808    EDW10860.2   

Proteomes

UP000005204    UP000053240    UP000053268    UP000218220    UP000007151    UP000037510    + More
UP000005203    UP000242457    UP000053105    UP000078540    UP000078541    UP000007755    UP000008237    UP000005205    UP000053825    UP000279307    UP000000311    UP000245037    UP000215335    UP000002358    UP000009046    UP000053097    UP000078542    UP000007266    UP000235965    UP000027135    UP000095301    UP000037069    UP000075809    UP000092444    UP000001819    UP000092445    UP000078200    UP000095300    UP000001292    UP000008711    UP000268350    UP000008744    UP000192221    UP000092443    UP000000803    UP000002282    UP000078492    UP000076858    UP000007801    UP000008792    UP000091820    UP000007798    UP000001070    UP000000305    UP000009192   

PRIDE

H9IUW8    Q6AWJ8    Q95V09    Q9NHE9    A1Z9D7   

Pfam

PF00058   Ldl_recept_b        + More
PF00057   Ldl_recept_a
PF00211   Guanylate_cyc

Interpro

IPR023415   LDLR_class-A_CS        + More
IPR000742   EGF-like_dom       
IPR011042   6-blade_b-propeller_TolB-like       
IPR000033   LDLR_classB_rpt       
IPR002172   LDrepeatLR_classA_rpt       
IPR036055   LDL_receptor-like_sf       
IPR001881   EGF-like_Ca-bd_dom       
IPR013032   EGF-like_CS       
IPR009030   Growth_fac_rcpt_cys_sf       
IPR029787   Nucleotide_cyclase       
IPR001054   A/G_cyclase       
IPR000152   EGF-type_Asp/Asn_hydroxyl_site       
IPR017049   LRP5/6       

SUPFAM

SSF57424   SSF57424        + More
SSF57184   SSF57184       
SSF55073   SSF55073       

Gene 3D

2.120.10.30     4.10.400.10    

CDD

cd00112  LDLa

ProteinModelPortal

H9IUW8   A0A2W1C4L5   A0A194RHB0   A0A2H1W340   A0A194Q7P7   A0A2A4JDU2   + More
A0A1E1WPK0   A0A212ERU9   A0A0L7LIC0   A0A1B6H952   A0A1B6KTB0   A0A1B6HTI9   A0A1V1FQJ8   A0A088AJF0   A0A2A3E6R5   A0A0M8ZSK8   A0A0A9YIG5   A0A151I365   A0A151JTX8   A0A1B6BXD2   F4X5W2   E2B7S9   A0A158NMF6   A0A0L7R7D2   A0A3L8DL26   E2A3U3   A0A2P8YCY9   A0A232ETC2   K7IYY2   A0A2H8TD26   A0A2S2P0K4   A0A2R7WEE8   A0A146LXD3   A0A1Y1M0S0   A0A224X518   A0A2S2QFY6   E0VCE3   A0A026WGG7   A0A195CCJ2   D2A038   A0A2J7QGD9   A0A067QSV8   A0A1I8MEY3   A0A0L0C8A9   A0A0P5YV12   W8BVL4   A0A0P5X248   A0A151WS83   Q6AWJ8   A0A1B0G7N5   Q28ZT5   A0A1A9ZGJ1   A0A1A9V5E9   A0A1I8PWX5   B4HQJ0   A0A0P5Y2D5   Q95V09   B3NRK7   A0A0J9RBX9   A0A3B0JQS3   B4GGT4   A0A1W4V4L1   A0A1A9XP08   A0A3B0JHZ3   Q9NHE9   A1Z9D7   B4P4H3   A0A0P5BA92   A0A0K8UBG2   A0A151J3V0   A0A0P5X114   A0A0P5BJ23   A0A0P5VEQ9   A0A0P5B9K8   A0A0P5VIK7   A0A0A1WEM1   A0A0P5AF92   A0A0P4YNR5   A0A0P5A807   A0A0P5V056   A0A0P4YGB1   A0A0P5U743   A0A0P5WWU6   A0A0N8A2S8   A0A0P5UPS1   A0A0P6IMF6   A0A0N8D0B5   A0A0P6G760   A0A0P5YXR7   A0A0P5DHF3   A0A0P5BCB8   A0A0P5D9M4   B3MGY8   B4MCL5   A0A0T6AX35   A0A1A9WIS8   B4MS00   B4JVN1   E9FT42   B4KML3  

PDB

4DG6     E-value=2.27417e-93,     Score=873

KEGG

101738889    K03068 low density lipoprotein receptor-related protein 5/6 | (RefSeq) low-density lipoprotein recep

GO

GO:0016021   GO:0005509   GO:0035556   GO:0009190   GO:0016849   GO:0017147   GO:0001745   GO:0005886   GO:0042813   GO:0007399   GO:0007616   GO:0048076   GO:0090254   GO:0008587   GO:0060070   GO:0005769   GO:0035223   GO:0005770   GO:0071936   GO:0007367   GO:0007275   GO:0015026  

Length:

414

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.64789

Exp number, first 60 AAs:

3.61301

Total prob of N-in:

0.21741

outside

1  -  414

 

 

Pi

27.26814

Theta

20.2499

Tajima's D

0.809626

CLR

0.327281

CSRT

0.615419229038548

Interpretation

Uncertain