Silkworm Genome Informatics Database

Gene

KWMTBOMO08059

Pre Gene Modal

BGIBMGA001042

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_probable_phospholipid-transporting_ATPase_VD_[Bombyx_mori]

Location

Bomo_Chr13(+):13829655-13846469 View in EpiBrowser

Full name

Phospholipid-transporting ATPase + More
P-type phospholipid transporter

Location in the cell

PlasmaMembrane Reliability : 2.653

CDS

ATGCTTGCATGTTTGTGTTACAGCGACATTAGTAGATCAGCCGAAAGATATGTTAAGGTGAAATGGAGGGACGTTCGAGTCGGCGACCTCGTTCACTTGTCTAACAACGAAGCGGTGCCAGCTGATATGGTGCTGCTGCACTCCTCCAATCCAATGGGGATCTGCTACCTGGACACGTGTAATCTGGACGGAGAGACAAACTTGAAACAGAGAATCGTCGCACCGGGCTTCAGAGAAAAGCGACTTGATTTTAATCCAATGAAATTCAGAAGTTCAATAGAAGTCGAAAGGCCTTCAACGAAAATCTACAGGGAATGCACGATCAAGAACACGGATTACGTCGAGGGTATCGTTGTGTACGCGGGACACGAGACCAAAGCCATGCTGAACAACGGGGGACCGCGATACAAATGCTCCGGTCTGGAGAAGAAAATGAACACAGACGTGATTTGGTGTGTTTTAGTGCTGCTATTCCTCTGCTGCGTTGGCGCCGCCTGTTACAAAGTCTGGTTGGACCAATACTTTCCCAATTTACTAAGATACACGCTTTTCATTCCGCAAGCTGACAAACCACCGGCGTACGAAGGCCTACAGATATTCTGGACCTACATTATAATATTACAAGTCATGATACCAATATCTCTGTACGTGACTATTGAGATGACGAAACTATTGCAAGTCTATCATATACATCAAGATATAGAAATGTACGATCCGGAGACGAACATCAGAACCGAATGCCGAGCGCTCAACATAACGGAGGAACTGGGACAGATAAGTTACTTGTTCAGCGATAAGACCGGAACGTTGACCGAGAACAAGATGGTGTTTAGGAGATGCACCGTTAACGGTGTCGATTACGATCACCCGCCTGGACCCCCCGCGGAACCCTCGACCGAACTCCCGCCCATTGTAACTCCTCTAACCCAAGTATCGCCAAACCGAAGACTGCTCCAACATCTAAACGACACAAACGATGCTCAACACACGCAAAAGGTTCGCGAGTTCCTCTTGATCTTGGCCGTCTGCAATACGGTGGTCGTGAGTCAGCCTCACGTGGACACGATGCAGCTCAGCATGTCGAATTCGGGCGAAGAACTGACGAACAACAGGAAACCATCGAGATCGAATGGTACATTACGATCAAACGACAAGTACGCTCGATTAACGGAATCGCGATCGACGACGCCCTCGCCACCGCCCTCGACCGTTTCCCCCCTGAAGATACGTCTGCCTAAACTGACGTTTGGTAGCAGAGACGACAACACCAGTGAACCGAGTACATCTACTGAACAACAGATCGCTCGTTTTGAAGCGGAAAGCCCGGACGAGCTAGCACTCGCTGAGGCGGCTCTCGCGTACGGCTACGAGCTGAGAAGCAGGTCGCCTGACGAGGTCGAGGTCGGGATCAAGGGGGAGGTGAGCCGCCTGAAGGTGCTTCGGGTGCAGCAGTTCGACTCCAACCGGAAATGCATGTCCGTCGCGATGCGGACGCCTACCGGTCAAGTAGTTTTGTACGTAAAAGGCGCTGATAGCACAGTGCTGGGCGCCTTGGCACCGATGCGGGCCGGCTCGGCGGAGGCGGCGGCGTGCGAGCGCACCCGCGCCCTCATCAGCGAATACTCGCGCGCCGGCCTCCGCACGCTGGTCATGGCCAAGCGCACCATGCAGCCCGCGCTGTGGGAGGAGTGGCTCGCCAGCCATACCAGAGCCTCGGAGATCGGAGAAGGCCGCGATAAGAGGATACGCGACTCGCTGACTCGGCTCGAGAGTGCCCTGACGCTGGTGGGGGCCACGGGGGTCGAGGACCGGCTGCAGGAGGACGTGCCGCGCACCGTCCGGGCGCTGCTCGACGCCGGGATCATCGTGTGGGTGCTGACCGGGGACAAGCCGGAGACCGCCATCAACATAGCGTACTCCGCCTCTCTGTTCTCACAGAGCGACCGGCTGTTGCACCTCATGTCCAGGGATAAGGAGCACGCGGAGTCCACGATCAAGAGTTACCTGGAGGGGGGTGTGGGGGGTGCGGGGCGCGCGCTGGTGGTGGACGGGCGCACGCTCACGTACATCCTGGACCGGCGCTCGGGGCTGGTGGCGCCGTTCCTGTGTCTGGCGCGGCGCTGCTCCGCCGTGCTGTGCTGCCGCGCCACGCCGCTGCAGAAGGCCTGCATCGTCAAGGCGGTGAAGGAAGAGCTCGGCGTGACGACCCTGGCCATAGGCGACGGCGCCAACGACGTCTCCATGATACAAACGGCTGACGTCGGCGTCGGTCTGTCTGGCCAGGAAGGTATGCAGGCGGTGATGGCTTCGGACTTCGCGCTGTCGAGGTTCAAGTTCATAGAGCGGCTGCTGCTCGTACACGGACACTGGTGCTATGACCGGCTCGCCAGGATGATACTGTATTTCTTCCTCAAAAATGCCACGTTCGTGTTCATGGTGTTCTGGTACCAGCTGTACTGCGGCTTCTCAGCTACGGTGATGATCGACCAGCTACACCTCATGGCCTACAACCTCATGTTCACCGCGCTACCACCCATCGTCATCGGTAAGCTCTCATCTACTCCAAACTTATAA

Protein

MLACLCYSDISRSAERYVKVKWRDVRVGDLVHLSNNEAVPADMVLLHSSNPMGICYLDTCNLDGETNLKQRIVAPGFREKRLDFNPMKFRSSIEVERPSTKIYRECTIKNTDYVEGIVVYAGHETKAMLNNGGPRYKCSGLEKKMNTDVIWCVLVLLFLCCVGAACYKVWLDQYFPNLLRYTLFIPQADKPPAYEGLQIFWTYIIILQVMIPISLYVTIEMTKLLQVYHIHQDIEMYDPETNIRTECRALNITEELGQISYLFSDKTGTLTENKMVFRRCTVNGVDYDHPPGPPAEPSTELPPIVTPLTQVSPNRRLLQHLNDTNDAQHTQKVREFLLILAVCNTVVVSQPHVDTMQLSMSNSGEELTNNRKPSRSNGTLRSNDKYARLTESRSTTPSPPPSTVSPLKIRLPKLTFGSRDDNTSEPSTSTEQQIARFEAESPDELALAEAALAYGYELRSRSPDEVEVGIKGEVSRLKVLRVQQFDSNRKCMSVAMRTPTGQVVLYVKGADSTVLGALAPMRAGSAEAAACERTRALISEYSRAGLRTLVMAKRTMQPALWEEWLASHTRASEIGEGRDKRIRDSLTRLESALTLVGATGVEDRLQEDVPRTVRALLDAGIIVWVLTGDKPETAINIAYSASLFSQSDRLLHLMSRDKEHAESTIKSYLEGGVGGAGRALVVDGRTLTYILDRRSGLVAPFLCLARRCSAVLCCRATPLQKACIVKAVKEELGVTTLAIGDGANDVSMIQTADVGVGLSGQEGMQAVMASDFALSRFKFIERLLLVHGHWCYDRLARMILYFFLKNATFVFMVFWYQLYCGFSATVMIDQLHLMAYNLMFTALPPIVIGKLSSTPNL

Catalytic Activity

ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Similarity

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.

Uniprot

H9IUW2 A0A212ERV6 A0A2A4K0N8 A0A194RCX0 A0A3S2NJ37 A0A2H1VTS1 + More
A0A2W1C037 A0A194Q650 U4U0G1 A0A336KFC8 A0A336KDK6 A0A3Q3LHG2 A0A3B4XIT5 A0A3Q2XHL2 A0A2B4SW24 A0A3B3WXE1 A0A3P9NFD8 A0A3P9NFC5 A0A3Q1AZZ1 A0A3P8P071 A0A315VKE5 A0A3Q0RBZ5 A0A3B4EPK4 A0A3B5LL55 A0A3Q2D9L1 M4A4G4 A0A3B5AEX2 A0A2I4B991 A0A2I4B985 A0A3Q3F2P1 A0A0J7L9T1 A0A3P8TT13

EC Number

7.6.2.1

Pubmed

19121390 22118469 26354079 28756777 23537049 29703783 + More
23542700

EMBL

BABH01000390 BABH01000391 AGBW02012947 OWR44181.1 NWSH01000278 PCG77807.1 + More
KQ460397 KPJ15314.1 RSAL01000023 RVE52278.1 ODYU01004396 SOQ44229.1 KZ149891 PZC79075.1 KQ459439 KPJ01012.1 KB631829 ERL86572.1 UFQS01000300 UFQT01000300 SSX02612.1 SSX22986.1 SSX02611.1 SSX22985.1 LSMT01000016 PFX33080.1 NHOQ01001578 PWA23561.1 LBMM01000107 KMR04921.1

Proteomes

UP000005204 UP000007151 UP000218220 UP000053240 UP000283053 UP000053268 + More
UP000030742 UP000261640 UP000261360 UP000264820 UP000225706 UP000261480 UP000242638 UP000257160 UP000265100 UP000261340 UP000261460 UP000261380 UP000265020 UP000002852 UP000261400 UP000192220 UP000264800 UP000036403 UP000265080

PRIDE

H9IUW2

Pfam

PF16212   PhoLip_ATPase_C        + More
PF16209   PhoLip_ATPase_N
PF01062   Bestrophin

Interpro

IPR018303   ATPase_P-typ_P_site        + More
IPR032630   P_typ_ATPase_c
IPR023214   HAD_sf
IPR036412   HAD-like_sf
IPR006539   P-type_ATPase_IV
IPR023299   ATPase_P-typ_cyto_dom_N
IPR001757   P_typ_ATPase
IPR023298   ATPase_P-typ_TM_dom_sf
IPR008250   ATPase_P-typ_transduc_dom_A_sf
IPR032631   P-type_ATPase_N
IPR030359   ATP10B
IPR021134   Bestrophin/UPF0187

SUPFAM

SSF81665   SSF81665        + More
SSF81653   SSF81653
SSF81660   SSF81660
SSF56784   SSF56784

Gene 3D

3.40.1110.10 3.40.50.1000

ProteinModelPortal

H9IUW2 A0A212ERV6 A0A2A4K0N8 A0A194RCX0 A0A3S2NJ37 A0A2H1VTS1 + More
A0A2W1C037 A0A194Q650 U4U0G1 A0A336KFC8 A0A336KDK6 A0A3Q3LHG2 A0A3B4XIT5 A0A3Q2XHL2 A0A2B4SW24 A0A3B3WXE1 A0A3P9NFD8 A0A3P9NFC5 A0A3Q1AZZ1 A0A3P8P071 A0A315VKE5 A0A3Q0RBZ5 A0A3B4EPK4 A0A3B5LL55 A0A3Q2D9L1 M4A4G4 A0A3B5AEX2 A0A2I4B991 A0A2I4B985 A0A3Q3F2P1 A0A0J7L9T1 A0A3P8TT13

PDB

6A69 E-value=7.53593e-12, Score=173

KEGG

101740011 K01530 phospholipid-translocating ATPase [EC:7.6.2.1] | (RefSeq) probable phospholipid-transporting

GO

GO:0004012 GO:0016021 GO:0000287 GO:0005524 GO:0000166 GO:0015914 GO:0046872 GO:0006412 GO:0016876 GO:0043039

PANTHER

PTHR24092 PTHR24092:SF79

Subcellular location

Membrane

Length:

857

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

85.8393800000003

Exp number, first 60 AAs:

0.00596

Total prob of N-in:

0.96548

inside

1 - 148

TMhelix

149 - 171

outside

172 - 196

TMhelix

197 - 219

inside

220 - 798

TMhelix

799 - 816

outside

817 - 830

TMhelix

831 - 853

inside

854 - 857

Pi

17.688628

Theta

15.668493

Tajima's D

0.260196

CLR

0.660245

CSRT

0.450077496125194

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics