Gene

KWMTBOMO08045  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001037

Annotation

PREDICTED:_leucine--tRNA_ligase?_cytoplasmic_[Bombyx_mori]

Location

Bomo_Chr13(+):13605105-13611349      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 3.323

CDS

ATGGCATTGGACAGGAAGGGTACATTCAAGGTTGAATATCTTCAGGAAATTGAGAAGAAAGTTCAGGAAAGATGGGAGAGCCAGAAGATTTTTGAAGTTGAAGCTCCTGATGATGGGAAATCACATGAGAAGTTTTTGTGTACTTTTCCATATCCATACATGAATGGACGCTTGCATTTGGGTCATACATTTTCTCTATCCAAATGTGAGTTTGCCTGCAGGTACTACCGGTTGAAAGGTAGAATGGTGCTGTTTCCATTTGGATTCCACTGTACTGGGATGCCGATTAAAGCTTGTGCTGATAAGCTAAAGCGAGAAATGGCTGTATATGGTTGTCCTCCAGTATTTCCTGAAGATGAGGAGTTAATTGTCAAGGATGAAGATATTATACCCAAAGACAAAAGTAAAGGCAAGAAAAGCAAAGCCGTAGCCAAGACTGGTGGTTCAAAGTACCAGTGGCAAATCATGAAGAGTATTGGTGTTCCTGAAGAGGAGATCAAAGAGTTTGCCAATGAAAGCTACTGGCTTGAATACTTCCCACCTCGTGCTGTTACAGATTTGAAGAGAATGGGTATTCATGTAGATTGGCGACGTAAGTTTATAACAACAGACGCCAATCCGTTCTATGATTCATTTATAAAATGGCAGTTCAACCACCTTAAAGATCGTAACAAGATAATGTACGGTAAAAGGTACACGATATTTTCGCCATTGGACAAACAACCTTGTATGGACCACGACAGAAGCACTGGTGAAGGGGCAGGACCACAGGAATATACTTTGATCAAGATGGTAGTGCTGGAACCGCTACCTAATTGCCTCATATCTCTTAAAGGCAAAAAGATAAGTTTAGTTGCGGCCACCCTTCGGCCAGAAACAATGTATGGTCAAACTAATTGCTGGGTGCACCCCGATATCAAATACATTGCGTTCGAAACCGTCAAAGACGGAGTGTTCATTTGCACAAAACGCGCCGCTCGGAATATGTCTTACCAAGATTTTACGGAAAAAGATGGAGAGTTCAAAATCTTACTGGAAATTGTTGGTCAGGATCTTCTAGGTTTGTCTGTACAATCTCCATTTACTTGCTATCCGAAGATCTATGCGCTTCCTATGCTAACAATCAAGGAAGACAAAGGCACTGGCATTGTAACTAGTGTTCCGTCAGATTCACCTGATGACTATGCAGCTTTAGTGGATTTGCAAAAGAAACCAGCTTTCAGGGAGAAGTATGGAATCGCAGATGACATGATCCTGCCTTTCAAACCAGTTCCTATTTTGGAAACACCCGATTTCGGCAACTTATCAGCTGTGTATTTGTATGACGAGCTAAAGATTCAAAGTCAGAATGACAGAGAGAAGTTAACTCAAGCCAAAGAAATGGTGTACCTCAAAGGGTTTTATGATGGAGTTCTGCTTGTGGGTGAACATAAAGGAAGTAAGATTCAAGATGTGAAGAAGAATTTACAAACAAAGTTAATCCAAGAGGGTAAAGCTGTGATATACTACGAGCCTGAGAAGACAATCATCTCTAGATCTGGAGATGAGTGTGTTGTAGCGCTTTGTAACCAATGGTATCTCGACTATGGCAATGAGGAATGGAAAGGCCAAGCTGAAAAAGCCCTTGAGGCCATGAATACTTATCATGATGAGGTCAGAAAAAATTTCCAGGCGACTTTGAAATGGCTTCACGAGTATGCATGTTCCAGGACTTATGGTCTTGGAACTAAATTACCTTGGGACCAGCAGTGGGTTATTGAGTCATTGTCTGACTCAACCATTTACAATGCCTATTACACAATTTCACATTTTCTACAAGGCGATACGTTTAGGGGAAACAAAGAGAATACTCTCAAAATTAAACCGGAACAAATGACTAGTGAAGTTTGGGATTACATCTTCTTCAAAGAGGCGCCTCTACCTAAAAATACTGTGATTGATAGAAAATCTTTAGATCTCATGAGAAAATCGTTTCAATTTTGGTACCCAGTTGACTTGAGAGTTTCTGGAAAAGACTTAATTCAGAACCATCTAACATTTTACATATACAATCACTGTGCAATGTGGCCCAATGAGGAAGAGAAATGGCCTAAAGGGATCAGAGCTAATGGTCATTTAATGTTGAACTCTGCAAAAATGTCCAAGTCGGAGGGAAACTTTTTGACGCTTTCCGAATCCATTGAGAAGTTTAGTGCCGATGGCATGAGACTTACATTGGCTGATGCAGGGGATTCCGTAGAAGATGCCAACTTTGTCGAGAGTACTGCGGACGCGGCGATATTGAGGCTGTATACTTTTATTGAGTGGGTCAAAGAAGTGCTCGCCTCGAAGTCAACTTTGAGAAGTGGTGACTACAATTTCCACGATAAAGTCTTCGTGAGCGAGATGAACATCAAGATACTGCAGACGGACGATAACTACAACAGGATGCTGTTCAAAGAGGCCCTGAAGAGTGGGTTCTTTGAGTTGCAGGCGGCCAGGGACAAGTACCGCGAGCTGTGCTCCGAGGGCGGGATGCACGTCGAGCTGGTCACCAAGTACATTGAAGTTCAGGCGAAGTTAATGTCGCCCATATGTCCGCACGTCGCCGAGTACGTCTGGGAACTGCTCGGTAACGTAAGTTCTAAGCTCGTCATTTTTTTTATTGCTTAG

Protein

MALDRKGTFKVEYLQEIEKKVQERWESQKIFEVEAPDDGKSHEKFLCTFPYPYMNGRLHLGHTFSLSKCEFACRYYRLKGRMVLFPFGFHCTGMPIKACADKLKREMAVYGCPPVFPEDEELIVKDEDIIPKDKSKGKKSKAVAKTGGSKYQWQIMKSIGVPEEEIKEFANESYWLEYFPPRAVTDLKRMGIHVDWRRKFITTDANPFYDSFIKWQFNHLKDRNKIMYGKRYTIFSPLDKQPCMDHDRSTGEGAGPQEYTLIKMVVLEPLPNCLISLKGKKISLVAATLRPETMYGQTNCWVHPDIKYIAFETVKDGVFICTKRAARNMSYQDFTEKDGEFKILLEIVGQDLLGLSVQSPFTCYPKIYALPMLTIKEDKGTGIVTSVPSDSPDDYAALVDLQKKPAFREKYGIADDMILPFKPVPILETPDFGNLSAVYLYDELKIQSQNDREKLTQAKEMVYLKGFYDGVLLVGEHKGSKIQDVKKNLQTKLIQEGKAVIYYEPEKTIISRSGDECVVALCNQWYLDYGNEEWKGQAEKALEAMNTYHDEVRKNFQATLKWLHEYACSRTYGLGTKLPWDQQWVIESLSDSTIYNAYYTISHFLQGDTFRGNKENTLKIKPEQMTSEVWDYIFFKEAPLPKNTVIDRKSLDLMRKSFQFWYPVDLRVSGKDLIQNHLTFYIYNHCAMWPNEEEKWPKGIRANGHLMLNSAKMSKSEGNFLTLSESIEKFSADGMRLTLADAGDSVEDANFVESTADAAILRLYTFIEWVKEVLASKSTLRSGDYNFHDKVFVSEMNIKILQTDDNYNRMLFKEALKSGFFELQAARDKYRELCSEGGMHVELVTKYIEVQAKLMSPICPHVAEYVWELLGNVSSKLVIFFIA

Similarity

Belongs to the class-I aminoacyl-tRNA synthetase family.
Belongs to the peptidase S1 family.

Uniprot

H9IUV7   A0A2A4JKL1   A0A194Q7M7   A0A194RCH5   A0A2H1W166   A0A212EX00   + More
S4PAL2   A0A1Y1KY55   A0A2J7PZ40   D2A1C9   A0A1W4X7L4   A0A0T6B471   A0A1B6DI73   A0A182Y3F3   A0A182QC67   A0A1B6ENK2   A0A1B6IUA7   B3MP31   B4I2Z8   A0A2M4BAM0   A0A0J9QV26   A0A2M4BAH6   A0A2M4BAN8   A0A067QKD3   Q8MRF8   A0A088AT22   Q9VQR8   B4NXX9   A0A182M5L9   A0A182RMD7   B4JQG2   T2FFJ2   A0A2A3EH20   W5J260   A0A182MZ05   A0A1S4GYI9   A0A182L0W2   A0A310S846   A0A2M4A110   A0A2M3ZFH0   A0A1Y9GLW8   A0A1Y9J0P1   A0A182U1G9   Q7Q495   A0A2M4A0S5   A0A154P8F7   A0A1W4UUG4   B4KK92   A0A182V6W9   A0A182W6N8   A0A182F4C6   A0A3F2YWI8   A0A1Q3G2K0   A0A0M4E9G2   U5EZJ1   T1PBJ8   B4MV75   A0A1I8PHA6   A0A0L0CHJ7   A0A182KDL7   A0A232F699   A0A1S4FDN6   B4LRU6   A0A182JFF4   B3N334   Q0IF77   K7JB56   A0A182G8J5   A0A1I8ML26   A0A3B0K0P6   A0A336LJP2   B4G9F6   Q29MC7   B4Q9L5   W8C385   A0A2H8TCZ3   A0A1B0FQF7   A0A1A9ZCT3   A0A0N8EMP0   A0A0P4YD83   A0A1A9VW15   A0A164L1X1   A0A0P5DN27   A0A0P6BJD7   A0A0N8BH58   A0A0P6GMF4   A0A2H8U104   A0A0N7ZL27   A0A0P5W1V5   A0A0P5H8Q5   A0A0P5P8X7   J9JXS8   A0A0P5PML6   A0A034VKN3   A0A0P5KVK0   A0A0P5NFA4   A0A1S3AF38   A0A0A1X064   A0A1L8DFT4   A0A195E4Z4  

Pubmed

19121390    26354079    22118469    23622113    28004739    18362917    + More
19820115    25244985    17994087    22936249    24845553    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    20920257    23761445    12364791    20966253    26108605    28648823    17510324    20075255    26483478    25315136    15632085    24495485    25348373    25830018   

EMBL

BABH01000420    BABH01000421    BABH01000422    NWSH01001158    PCG72316.1    KQ459439    + More
KPJ01000.1    KQ460397    KPJ15302.1    ODYU01005711    SOQ46831.1    AGBW02011847    OWR46026.1    GAIX01004956    JAA87604.1    GEZM01073447    JAV65090.1    NEVH01020341    PNF21601.1    KQ971338    EFA02651.1    LJIG01009893    KRT82169.1    GEDC01011897    GEDC01000955    JAS25401.1    JAS36343.1    AXCN02000789    GECZ01031949    GECZ01030259    JAS37820.1    JAS39510.1    GECU01017198    JAS90508.1    CH902620    EDV31197.1    CH480820    EDW54143.1    GGFJ01000911    MBW50052.1    CM002910    KMY87908.1    GGFJ01000913    MBW50054.1    GGFJ01000910    MBW50051.1    KK853238    KDR09525.1    AY119663    AAM50317.1    AE014134    AAF51096.2    AHN54104.1    CM000157    EDW87550.1    AXCM01010852    CH916372    EDV99142.1    BT150267    AGV77169.1    KZ288254    PBC30754.1    ADMH02002138    ETN58342.1    AAAB01008964    KQ773364    OAD52391.1    GGFK01001089    MBW34410.1    GGFM01006555    MBW27306.1    APCN01000798    EAA12235.2    GGFK01001086    MBW34407.1    KQ434844    KZC08152.1    CH933807    EDW12623.1    GFDL01001059    JAV33986.1    CP012523    ALC38838.1    GANO01000704    JAB59167.1    KA645348    AFP59977.1    CH963857    EDW76420.2    JRES01000387    KNC31730.1    NNAY01000908    OXU25969.1    CH940649    EDW64698.1    CH954177    EDV57633.1    CH477389    EAT42009.1    AAZX01003703    AAZX01004297    AAZX01008058    JXUM01047822    KQ561534    KXJ78242.1    OUUW01000004    SPP79186.1    UFQS01000037    UFQT01000037    SSW98018.1    SSX18404.1    CH479180    EDW28986.1    CH379060    EAL33767.2    CM000361    EDX03626.1    GAMC01006209    JAC00347.1    GFXV01000159    MBW11964.1    CCAG010020679    GDIQ01011748    JAN82989.1    GDIP01229110    JAI94291.1    LRGB01003216    KZS03725.1    GDIP01153684    JAJ69718.1    GDIP01014065    JAM89650.1    GDIQ01178195    GDIQ01109971    JAK73530.1    GDIQ01041750    JAN52987.1    GFXV01008064    MBW19869.1    GDIP01234921    JAI88480.1    GDIP01093078    JAM10637.1    GDIQ01231286    GDIQ01123123    JAK20439.1    GDIQ01138169    JAL13557.1    ABLF02032796    ABLF02032798    GDIQ01228985    GDIQ01126870    GDIQ01125169    JAL24856.1    GAKP01016295    JAC42657.1    GDIQ01183887    JAK67838.1    GDIQ01146510    JAL05216.1    GBXI01010249    JAD04043.1    GFDF01008890    JAV05194.1    KQ979657    KYN19972.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000235965    + More
UP000007266    UP000192223    UP000076408    UP000075886    UP000007801    UP000001292    UP000027135    UP000005203    UP000000803    UP000002282    UP000075883    UP000075900    UP000001070    UP000242457    UP000000673    UP000075884    UP000075882    UP000075840    UP000076407    UP000075902    UP000007062    UP000076502    UP000192221    UP000009192    UP000075903    UP000075920    UP000069272    UP000075885    UP000092553    UP000007798    UP000095300    UP000037069    UP000075881    UP000215335    UP000008792    UP000075880    UP000008711    UP000008820    UP000002358    UP000069940    UP000249989    UP000095301    UP000268350    UP000008744    UP000001819    UP000000304    UP000092444    UP000092445    UP000078200    UP000076858    UP000007819    UP000079721    UP000078492   

PRIDE

H9IUV7    Q8MRF8    Q9VQR8    T2FFJ2   

Pfam

PF00133   tRNA-synt_1        + More
PF08264   Anticodon_1
PF10228   DUF2228
PF10283   zf-CCHH
PF09334   tRNA-synt_1g
PF00089   Trypsin

Interpro

IPR001412   aa-tRNA-synth_I_CS        + More
IPR009008   Val/Leu/Ile-tRNA-synth_edit       
IPR002300   aa-tRNA-synth_Ia       
IPR013155   M/V/L/I-tRNA-synth_anticd-bd       
IPR009080   tRNAsynth_Ia_anticodon-bd       
IPR004493   Leu-tRNA-synth_Ia_arc/euk       
IPR019361   HPF1       
IPR019406   APLF_PBZ       
IPR014729   Rossmann-like_a/b/a_fold       
IPR015413   Methionyl/Leucyl_tRNA_Synth       
IPR033116   TRYPSIN_SER       
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR018114   TRYPSIN_HIS       
IPR001254   Trypsin_dom       
IPR013783   Ig-like_fold       

SUPFAM

SSF50677   SSF50677        + More
SSF47323   SSF47323       
SSF50494   SSF50494       

Gene 3D

3.40.50.620     3.90.740.10     2.60.40.10    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9IUV7   A0A2A4JKL1   A0A194Q7M7   A0A194RCH5   A0A2H1W166   A0A212EX00   + More
S4PAL2   A0A1Y1KY55   A0A2J7PZ40   D2A1C9   A0A1W4X7L4   A0A0T6B471   A0A1B6DI73   A0A182Y3F3   A0A182QC67   A0A1B6ENK2   A0A1B6IUA7   B3MP31   B4I2Z8   A0A2M4BAM0   A0A0J9QV26   A0A2M4BAH6   A0A2M4BAN8   A0A067QKD3   Q8MRF8   A0A088AT22   Q9VQR8   B4NXX9   A0A182M5L9   A0A182RMD7   B4JQG2   T2FFJ2   A0A2A3EH20   W5J260   A0A182MZ05   A0A1S4GYI9   A0A182L0W2   A0A310S846   A0A2M4A110   A0A2M3ZFH0   A0A1Y9GLW8   A0A1Y9J0P1   A0A182U1G9   Q7Q495   A0A2M4A0S5   A0A154P8F7   A0A1W4UUG4   B4KK92   A0A182V6W9   A0A182W6N8   A0A182F4C6   A0A3F2YWI8   A0A1Q3G2K0   A0A0M4E9G2   U5EZJ1   T1PBJ8   B4MV75   A0A1I8PHA6   A0A0L0CHJ7   A0A182KDL7   A0A232F699   A0A1S4FDN6   B4LRU6   A0A182JFF4   B3N334   Q0IF77   K7JB56   A0A182G8J5   A0A1I8ML26   A0A3B0K0P6   A0A336LJP2   B4G9F6   Q29MC7   B4Q9L5   W8C385   A0A2H8TCZ3   A0A1B0FQF7   A0A1A9ZCT3   A0A0N8EMP0   A0A0P4YD83   A0A1A9VW15   A0A164L1X1   A0A0P5DN27   A0A0P6BJD7   A0A0N8BH58   A0A0P6GMF4   A0A2H8U104   A0A0N7ZL27   A0A0P5W1V5   A0A0P5H8Q5   A0A0P5P8X7   J9JXS8   A0A0P5PML6   A0A034VKN3   A0A0P5KVK0   A0A0P5NFA4   A0A1S3AF38   A0A0A1X064   A0A1L8DFT4   A0A195E4Z4  

PDB

1WKB     E-value=7.23664e-127,     Score=1166

KEGG

101739599    K01869 leucyl-tRNA synthetase [EC:6.1.1.4] | (RefSeq) leucine--tRNA ligase, cytoplasmic

GO

GO:0005524   GO:0006429   GO:0002161   GO:0004823   GO:0042060   GO:0017101   GO:0005737   GO:0004832   GO:0004252   GO:0016021   GO:0006418   GO:0000166   GO:0004812   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR45794  

Length:

883

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.15786

Exp number, first 60 AAs:

0.00029

Total prob of N-in:

0.00680

outside

1  -  883

 

 

Pi

16.98079

Theta

14.762729

Tajima's D

-0.542235

CLR

0.488847

CSRT

0.236838158092095

Interpretation

Uncertain