Gene

KWMTBOMO08034  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001031

Annotation

troponin_I_transcript_variant_C_[Bombyx_mandarina]

Location

Bomo_Chr13(+):13284150-13300880      View in EpiBrowser

Full name

Troponin I      

Alternative Name

Protein heldup
Protein wings apart-A

Location in the cell

Nuclear   Reliability : 3.542

CDS

ATGGCGGATGATGAAGCGAAGAAGGCCAAACAGGCCGAAATCGACCGCAAGCGCGCTGAGGTGCGCAAGCGCATGGAGGAGGCCTCCAAAGCCAAAAAGGCGAAGAAGGGTTTCATGACACCTGAGAGGAAGAAGAAGCTCAGGTTGCTGCTGCGTAAGAAAGCCGCCGAAGAGTTGAAGAAGGAGCAGGAACGTAAAGCTGCTGAAAGGAGGCGCATCATCGAGGAGAGGTGCGGTAAACCTAAGAACATTGACGACGCCAACGAAGATACTATTAAGAGGGTTTGCAAAGACTACCATGAACGCATCGCTCGTCTTGAAGATGAAAAATTCGATCTGGAATACATCGTTAAAAGGAAAGATATGGAGATCTCCGACCTGAACTCCCAAGTCAACGACCTCAGAGGCAAATTCGTCAAGCCCACACTAAAGAAGGTTTCCAAATACGAAAACAAATTCGCCAAGCTCCAGAAGAAGGCCGCCGAATTCAACTTCCGTAACCAATTGAAGGTCGTGAAAAAGAAGGAATTCACCTTGGAAGAGGAAGACAAAGAGAAAAAGCCTGACTGGTCGAAGGGCAAGCCGGGAGATCAGAAGGTAAAAGAAGAAGAGGTTGAGGCATGA

Protein

MADDEAKKAKQAEIDRKRAEVRKRMEEASKAKKAKKGFMTPERKKKLRLLLRKKAAEELKKEQERKAAERRRIIEERCGKPKNIDDANEDTIKRVCKDYHERIARLEDEKFDLEYIVKRKDMEISDLNSQVNDLRGKFVKPTLKKVSKYENKFAKLQKKAAEFNFRNQLKVVKKKEFTLEEEDKEKKPDWSKGKPGDQKVKEEEVEA

Description

Troponin I is the ATPase inhibitory subunit of troponin in the thin filament regulatory complex. Involved in the development and maintenance of muscle and nervous system. May also be involved in the cytoskeletal apparatus.

Subunit

Binds to actin and tropomyosin.

Similarity

Belongs to the troponin I family.

Keywords

Acetylation   Actin-binding   Alternative splicing   Calcium   Complete proteome   Metal-binding   Methylation   Muscle protein   Reference proteome  

Feature

chain  Troponin I
splice variant  In isoform 1, isoform 2, isoform 3, isoform 4, isoform 5, isoform 6, isoform 7 and isoform 8.

Uniprot

C0LZ17   Q5FYZ4   S4PX88   B0FMT1   A0A1E1W4K8   I4DLU5   + More
I4DID2   A0A1E1WP35   A0A3S2NT05   C0LZ16   A0A2H8TCY8   C4WYE4   A0A1Q3G4T0   Q16RS8   A0A023EJH7   B1Q289   Q7PI45   Q16RS7   T1E7Q2   A0A1Q3G4S5   A0A1D1YGD7   J9JZJ7   A0A1B6FBE2   A0A1J1IX97   A0A1Q3FVF0   A0A158NBF8   A0A2J7R2L7   A0A158NBF7   A0A1B6KT69   V5GWT2   V5GKV6   V9I9Z9   E2IFW5   F5HLW1   Q3B708   A0A084VV58   A0A182JAY2   A0A1B6CBF4   A0A1B6CA82   R4UML9   Q16RS4   A0A1Q3G4E8   A0A1Q3G4U2   A0A1B6MB80   A0A1B6MG61   A0A1B6LX63   A0A1B6CHI2   A0A336JWA1   A0A182M6D3   A0A1Q3FVG1   A0A1B6MGS5   A0A1B6DPR7   A0A1Y1MRX4   A0A2J7R2S2   Q16RS5   A0A1Y1MTF8   A0A336K096   A0A1B6M7C4   T1E7T7   Q16RS3   A0A224XY97   A0A386IPD5   A0A161MYT1   R4G4J6   A0A1L8EH71   D3TLI1   A0A386IQC1   A0A0R3P6N5   I7LRG0   A0A386IQ20   A0A2M4CT66   A0A1I8N0M9   A0A1Y1MV94   F5HLV8   A0A1J1J1N8   A0A336LHS7   A0A1B6M0T8   A0A1Y1MRY5   A0A1Y1MRV3   A0A0R1EC43   A0A0Q5TGP9   A0A1W4UN55   Q16RS9   A0A1J1IXF2   A0A1Y1MRZ3   A0A182GKF6   P36188-5   E4NKJ4   A0A1B6MCQ3   A0A1J1IWW9   A0A1I8N0N2   C0M4Y3   A0A1Q3FVE5   B0X514   U5EPN5   P36188-3   A0A1W4V0Y7   E4NKM1   A0A0R1EIN8   B3NTA9  

Pubmed

23622113    22651552    17510324    24945155    16049195    12364791    + More
14747013    17210077    21347285    24438588    28004739    30243801    20353571    15632085    17994087    25315136    17550304    26483478    1899228    1908472    10731132    12537572    12537569    7680094   

EMBL

FJ785830    ACN86370.1    AY873787    AAW66633.1    GAIX01005463    JAA87097.1    + More
EU339105    ABY56688.1    GDQN01009160    JAT81894.1    AK402263    BAM18885.1    AK401050    BAM17672.1    GDQN01002299    JAT88755.1    RSAL01000232    RVE43813.1    FJ785829    ACN86369.1    GFXV01000145    MBW11950.1    AK343147    BAH72914.1    GFDL01000237    JAV34808.1    CH477697    EAT37120.1    GAPW01004451    JAC09147.1    BK005280    DAA05511.1    AAAB01008958    EAA44285.4    EGK97269.1    EAT37118.1    GAMD01002847    JAA98743.1    GFDL01000240    JAV34805.1    GDJX01014247    JAT53689.1    ABLF02025069    GECZ01022274    JAS47495.1    CVRI01000063    CRL04775.1    GFDL01003455    JAV31590.1    ADTU01011040    ADTU01011041    NEVH01007828    PNF35071.1    GEBQ01025347    JAT14630.1    GALX01003738    JAB64728.1    GALX01003737    JAB64729.1    JR037702    AEY57925.1    HM484304    ADK45364.1    EGK97272.1    BK005282    DAA05519.1    ATLV01017154    ATLV01017155    KE525157    KFB41852.1    GEDC01026506    JAS10792.1    GEDC01026954    JAS10344.1    KC571871    AGM32370.1    EAT37116.1    GFDL01000360    JAV34685.1    GFDL01000232    JAV34813.1    GEBQ01006796    JAT33181.1    GEBQ01005073    JAT34904.1    GEBQ01011710    JAT28267.1    GEDC01024400    JAS12898.1    UFQS01000005    UFQT01000005    SSW96924.1    SSX17311.1    AXCM01004805    GFDL01003456    JAV31589.1    GEBQ01004865    JAT35112.1    GEDC01009630    JAS27668.1    GEZM01023340    JAV88454.1    PNF35129.1    EAT37112.1    GEZM01023346    JAV88448.1    SSW96925.1    SSX17312.1    GEBQ01008184    JAT31793.1    GAMD01002762    JAA98828.1    EAT37114.1    GFTR01003415    JAW13011.1    MH001571    AYD60125.1    GEMB01003823    JAR99431.1    GAHY01000716    JAA76794.1    GFDG01000795    JAV18004.1    EZ422283    ADD18559.1    MH001573    AYD60127.1    CH379065    KRT07253.1    BK001655    DAA01990.1    MH001575    AYD60129.1    GGFL01004277    MBW68455.1    GEZM01023344    JAV88450.1    EGK97268.1    EGK97271.1    CRL04777.1    SSW96923.1    SSX17310.1    GEBQ01010440    JAT29537.1    GEZM01023351    JAV88443.1    GEZM01023352    JAV88442.1    CM000162    KRK06921.1    CH954180    KQS30039.1    EAT37113.1    CRL04776.1    GEZM01023341    JAV88453.1    JXUM01069864    KQ562574    KXJ75564.1    X58188    X59376    AE014298    AY122145    BT125791    ADR32375.1    GEBQ01006265    JAT33712.1    CRL04779.1    FJ810196    ACN79504.1    GFDL01003464    JAV31581.1    DS232361    EDS40629.1    GANO01003648    JAB56223.1    BT125818    ADR71727.1    KRK06922.1    EDV46560.2   

Proteomes

UP000283053    UP000008820    UP000007062    UP000007819    UP000183832    UP000005205    + More
UP000235965    UP000030765    UP000075880    UP000075883    UP000001819    UP000095301    UP000002282    UP000008711    UP000192221    UP000069940    UP000249989    UP000000803    UP000002320   

PRIDE

Q5FYZ4    Q3B708    P36188    E4NKJ4    E4NKM1   

Pfam

PF00992   Troponin

Interpro

IPR038077   Troponin_sf        + More
IPR001978   Troponin       

Gene 3D

1.20.5.350    

ProteinModelPortal

C0LZ17   Q5FYZ4   S4PX88   B0FMT1   A0A1E1W4K8   I4DLU5   + More
I4DID2   A0A1E1WP35   A0A3S2NT05   C0LZ16   A0A2H8TCY8   C4WYE4   A0A1Q3G4T0   Q16RS8   A0A023EJH7   B1Q289   Q7PI45   Q16RS7   T1E7Q2   A0A1Q3G4S5   A0A1D1YGD7   J9JZJ7   A0A1B6FBE2   A0A1J1IX97   A0A1Q3FVF0   A0A158NBF8   A0A2J7R2L7   A0A158NBF7   A0A1B6KT69   V5GWT2   V5GKV6   V9I9Z9   E2IFW5   F5HLW1   Q3B708   A0A084VV58   A0A182JAY2   A0A1B6CBF4   A0A1B6CA82   R4UML9   Q16RS4   A0A1Q3G4E8   A0A1Q3G4U2   A0A1B6MB80   A0A1B6MG61   A0A1B6LX63   A0A1B6CHI2   A0A336JWA1   A0A182M6D3   A0A1Q3FVG1   A0A1B6MGS5   A0A1B6DPR7   A0A1Y1MRX4   A0A2J7R2S2   Q16RS5   A0A1Y1MTF8   A0A336K096   A0A1B6M7C4   T1E7T7   Q16RS3   A0A224XY97   A0A386IPD5   A0A161MYT1   R4G4J6   A0A1L8EH71   D3TLI1   A0A386IQC1   A0A0R3P6N5   I7LRG0   A0A386IQ20   A0A2M4CT66   A0A1I8N0M9   A0A1Y1MV94   F5HLV8   A0A1J1J1N8   A0A336LHS7   A0A1B6M0T8   A0A1Y1MRY5   A0A1Y1MRV3   A0A0R1EC43   A0A0Q5TGP9   A0A1W4UN55   Q16RS9   A0A1J1IXF2   A0A1Y1MRZ3   A0A182GKF6   P36188-5   E4NKJ4   A0A1B6MCQ3   A0A1J1IWW9   A0A1I8N0N2   C0M4Y3   A0A1Q3FVE5   B0X514   U5EPN5   P36188-3   A0A1W4V0Y7   E4NKM1   A0A0R1EIN8   B3NTA9  

PDB

4Y99     E-value=0.00011244,     Score=105

KEGG

692734    no KO assigned | (RefSeq) TpnI, Wupa; troponin I

GO

GO:0005861   GO:0007399   GO:0048738   GO:0045214   GO:0007507   GO:0030239   GO:0046872   GO:0000280   GO:0046716   GO:0007517   GO:0005865   GO:0060047   GO:0003779   GO:0007519   GO:0006355   GO:0005975   GO:0016021   GO:0016020   GO:0005524   GO:0006412   GO:0016876   GO:0043039  

Length:

207

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.30359

outside

1  -  207

 

 

Pi

26.059749

Theta

23.820454

Tajima's D

0.142467

CLR

0.395544

CSRT

0.419729013549323

Interpretation

Uncertain