Gene

KWMTBOMO08029

Pre Gene Modal

BGIBMGA001129

Annotation

PREDICTED:_glucosylceramidase-like_[Bombyx_mori]

Location

Bomo_Chr13(-):13091991-13097084      View in EpiBrowser

Full name

Glucosylceramidase      

Location in the cell

Cytoplasmic   Reliability : 1.815

CDS

ATGGCATACACTAGTACCAATGACGGACTTCGTTTCTCTAAAAGTCAGGGTCAAGTTACGCACGATGAACAATTTGATGCTTCGGTCGCTGAAAAACACGAGAGTTTGCCTAAAGAATTCGATTTCTTCACGACTGGTGTTGTTTTAAGAGTGGACAGCACCATCAAGTTTCAAACAATAGAAGGATTCGGTGGAGCGGTAACCGATGCTGCGTCTTTGAACTGGAGGAAGCTTCCACCGGCCGCACAGGATAAGCTAATCGAAACCTACTTCGGTCCAAATGGCTTGGAATATAATATGATGCGAGTACCAATCGGCGGATCTGACTTTTCAACCCACCCTTACACTTACAATGAACAACCCTGGAACGATACTGAACTCTCGAATTTCTCCCTAACGAATGAGGATATTTCTTTCAAGATACCAATGATTCAGAATTGTATAAAGGCAGCGACTAGTGAGATACACATAACCGCTACAACGTGGTCGCCTCCGGTTTGGATGAAAACAAACGAAAAAATATCTGGCTATGGACAGCTCAAAACCGAATATTACCAGATTTACGCAGATTATCATTTGCGATTCTTGGAAGAATATAAGAAACACGACATCCATATATGGGCCATCACTACAACTAATGAACCAGTCAATGGTATCATACCGGTGGTTACGTTCAATTCTATGGGATGGATTCCTTCGCAATTAGGTCGTTGGATAGAAAACAACCTCGGCCCTACAATAAGGAAGTCTGTTTTCAATAGAACATTAATTCTTGGTGTTGACGACCAGAGGCTGATGCTGTCTGCTTACATGCTAGGAATGGAGAAAGCCGCACCAAACTCCATCAATTATTTAGATGGTATAGCAGTACATTATTATGAAGATTTCGTTTCACCTGAAATTCTTACAAATCTACACAAACGTTATCCAACGAAAATTATAGTTGCCACAGAAGCATGTGAAGGTGCGTATCCTTGGGAAACCTCTAAAGTTAAGATCGGATCTTGGGACAGAGCACAGAACTATGTCAAAGACATTATAGAGGTAATTCATAAATTGTTGTAA

Protein

MAYTSTNDGLRFSKSQGQVTHDEQFDASVAEKHESLPKEFDFFTTGVVLRVDSTIKFQTIEGFGGAVTDAASLNWRKLPPAAQDKLIETYFGPNGLEYNMMRVPIGGSDFSTHPYTYNEQPWNDTELSNFSLTNEDISFKIPMIQNCIKAATSEIHITATTWSPPVWMKTNEKISGYGQLKTEYYQIYADYHLRFLEEYKKHDIHIWAITTTNEPVNGIIPVVTFNSMGWIPSQLGRWIENNLGPTIRKSVFNRTLILGVDDQRLMLSAYMLGMEKAAPNSINYLDGIAVHYYEDFVSPEILTNLHKRYPTKIIVATEACEGAYPWETSKVKIGSWDRAQNYVKDIIEVIHKLL

Catalytic Activity

a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose

Similarity

Belongs to the glycosyl hydrolase 30 family.

Feature

chain  Glucosylceramidase

Uniprot

A0A194Q614   A0A212FNA8   A0A194PPY1   H9JUB6   A0A212F248   A0A194RBR5   + More
A0A2H1VUS0   A0A1W1EGM7   A0A1B6LUZ4   A0A1B6IGC1   A0A1B6K1N7   A0A3S2NLJ3   A0A1B6FTD6   A0A2A4K975   J9K5F8   A0A2J7R6I8   A0A1B6J3H7   A0A2J7R6J3   A0A2H1VST3   A0A2H1X380   A0A2J7R6J1   A0A2H1VG50   A0A0P5UEK4   A0A2A4K8P8   A0A212F254   A0A0P5UKE0   A0A0N8CP26   A0A0N1IF15   A0A0P5V259   A0A0P5V115   A0A067QM95   A0A0P5VAG5   A0A154P4F4   A0A0P5D4A0   A0A0N8BXP2   A0A0N8C3M9   A0A0P6HWY3   A0A2A3EMA9   A0A0L7QMS7   A0A0P6CTA3   A0A212F293   A0A0C9QXG4   A0A0P5BCG5   H9JUB7   A0A0P5UX07   A0A0P5YE76   A0A088APM4   A0A0P5BE18   T1JDD3   I4DLH0   A0A0P4Y4V0   A0A1B6CTI6   A0A0P5UAZ3   A0A0P6GJR3   A0A0N8DE38   A0A0P5Y055   A0A0P5X813   A0A0P5XUP8   A0A0P5YNS9   A0A162QRA1   A0A0P5XL26   A0A0P5Y2L0   A0A0N8A576   A0A0P5WP50   A0A0P5MXS5   A0A0P5BMC7   A0A0P5V0B5   A0A0P5Z7Y2   A0A0P6E3A7   A0A0P5X120   A0A0P6HUV1   A0A0P5E3J3   A0A195ECY0   A0A0P6EID0   A0A0P5UYZ4   A0A158NXS0   A0A0P5KKG2   A0A139WEE1   A0A151WMN1   A0A182PGK5   A0A210PEG6   A0A0P5I7D4   A0A0P5E440   A0A0P5CYJ3   A0A0P4YDK7   A0A0P5X901   A0A0P5UNV0   A0A0P5W3J8   A0A1Z5LER5   A0A0P5TR24   A0A0P4Z558   A0A0P5MS98   A0A0P5TRY0   B3P8F6   B3LY63   A0A0P6EF37   A0A293LVV1   A0A0P5UUQ5   Q7PXX9   K7IX35  

EC Number

3.2.1.45

Pubmed

26354079    22118469    19121390    28680679    24845553    22651552    + More
21347285    18362917    19820115    28812685    28528879    17994087    18057021    12364791    14747013    17210077    20075255   

EMBL

KQ459439    KPJ00977.1    AGBW02006772    OWR55189.1    KQ459602    KPI93190.1    + More
BABH01038539    BABH01038540    BABH01038541    AGBW02010783    OWR47794.1    KQ460397    KPJ15278.1    ODYU01004571    SOQ44585.1    LT635665    SGZ49395.1    GEBQ01024969    GEBQ01012479    JAT15008.1    JAT27498.1    GECU01021735    JAS85971.1    GECU01002337    JAT05370.1    RSAL01000008    RVE53974.1    GECZ01016297    JAS53472.1    NWSH01000035    PCG80448.1    ABLF02017156    ABLF02017157    ABLF02017158    ABLF02017160    ABLF02043031    ABLF02044170    NEVH01006756    PNF36451.1    GECU01013983    JAS93723.1    PNF36457.1    ODYU01004232    SOQ43893.1    ODYU01013051    SOQ59702.1    PNF36452.1    ODYU01002190    SOQ39362.1    GDIP01114152    JAL89562.1    PCG80449.1    OWR47828.1    GDIP01111638    JAL92076.1    GDIP01112839    JAL90875.1    KQ461178    KPJ07773.1    GDIP01105549    JAL98165.1    GDIP01105548    JAL98166.1    KK853153    KDR10552.1    GDIP01102691    JAM01024.1    KQ434814    KZC06829.1    GDIP01163230    LRGB01000311    JAJ60172.1    KZS19886.1    GDIQ01134723    JAL17003.1    GDIQ01118027    JAL33699.1    GDIQ01028607    JAN66130.1    KZ288219    PBC32336.1    KQ414868    KOC59952.1    GDIP01009481    JAM94234.1    OWR47849.1    GBYB01005352    JAG75119.1    GDIP01186374    JAJ37028.1    BABH01038531    BABH01038532    BABH01038533    BABH01038534    GDIP01107443    JAL96271.1    GDIP01073106    JAM30609.1    GDIP01190080    JAJ33322.1    JH432104    AK402138    BAM18760.1    GDIP01234780    JAI88621.1    GEDC01023766    GEDC01020570    GEDC01011572    GEDC01003214    JAS13532.1    JAS16728.1    JAS25726.1    JAS34084.1    GDIP01115596    JAL88118.1    GDIQ01034555    JAN60182.1    GDIP01042743    JAM60972.1    GDIP01065954    JAM37761.1    GDIP01077038    JAM26677.1    GDIP01067454    JAM36261.1    GDIP01056052    JAM47663.1    KZS19887.1    GDIP01070494    JAM33221.1    GDIP01077037    JAM26678.1    GDIP01181329    JAJ42073.1    GDIP01083544    JAM20171.1    GDIQ01149727    JAL01999.1    GDIP01182978    JAJ40424.1    GDIP01107444    JAL96270.1    GDIP01060297    JAM43418.1    GDIQ01068405    JAN26332.1    GDIP01079198    JAM24517.1    GDIQ01038503    JAN56234.1    GDIP01147339    JAJ76063.1    KQ979074    KYN23063.1    GDIQ01076099    JAN18638.1    GDIP01107445    JAL96269.1    ADTU01003452    ADTU01003453    ADTU01003454    ADTU01003455    GDIQ01183956    JAK67769.1    KQ971354    KYB26348.1    KQ982934    KYQ49129.1    NEDP02076748    OWF34883.1    GDIQ01222210    JAK29515.1    GDIP01153134    JAJ70268.1    GDIP01167885    JAJ55517.1    GDIP01231735    JAI91666.1    GDIP01075597    JAM28118.1    GDIP01111697    JAL92017.1    GDIP01091491    LRGB01002227    JAM12224.1    KZS08348.1    GFJQ02001071    JAW05899.1    GDIP01125091    JAL78623.1    GDIP01218434    JAJ04968.1    GDIQ01152677    JAK99048.1    GDIP01122885    JAL80829.1    CH954182    EDV53980.1    CH902617    EDV43967.1    KPU80566.1    GDIQ01076098    JAN18639.1    GFWV01007904    MAA32634.1    GDIP01125092    JAL78622.1    AAAB01008987    EAA00933.5    AAZX01006377    AAZX01006727   

Proteomes

UP000053268    UP000007151    UP000005204    UP000053240    UP000283053    UP000218220    + More
UP000007819    UP000235965    UP000027135    UP000076502    UP000076858    UP000242457    UP000053825    UP000005203    UP000078492    UP000005205    UP000007266    UP000075809    UP000075885    UP000242188    UP000008711    UP000007801    UP000007062    UP000002358   

PRIDE

H9JUB6    H9JUB7   

Pfam

PF02055   Glyco_hydro_30        + More
PF17189   Glyco_hydro_30C

Interpro

IPR001139   Glyco_hydro_30        + More
IPR017853   Glycoside_hydrolase_SF       
IPR033452   GH30_C       
IPR033453   Glyco_hydro_30_TIM-barrel       
IPR013780   Glyco_hydro_b       

SUPFAM

SSF51445   SSF51445       

Gene 3D

2.60.40.1180    

ProteinModelPortal

A0A194Q614   A0A212FNA8   A0A194PPY1   H9JUB6   A0A212F248   A0A194RBR5   + More
A0A2H1VUS0   A0A1W1EGM7   A0A1B6LUZ4   A0A1B6IGC1   A0A1B6K1N7   A0A3S2NLJ3   A0A1B6FTD6   A0A2A4K975   J9K5F8   A0A2J7R6I8   A0A1B6J3H7   A0A2J7R6J3   A0A2H1VST3   A0A2H1X380   A0A2J7R6J1   A0A2H1VG50   A0A0P5UEK4   A0A2A4K8P8   A0A212F254   A0A0P5UKE0   A0A0N8CP26   A0A0N1IF15   A0A0P5V259   A0A0P5V115   A0A067QM95   A0A0P5VAG5   A0A154P4F4   A0A0P5D4A0   A0A0N8BXP2   A0A0N8C3M9   A0A0P6HWY3   A0A2A3EMA9   A0A0L7QMS7   A0A0P6CTA3   A0A212F293   A0A0C9QXG4   A0A0P5BCG5   H9JUB7   A0A0P5UX07   A0A0P5YE76   A0A088APM4   A0A0P5BE18   T1JDD3   I4DLH0   A0A0P4Y4V0   A0A1B6CTI6   A0A0P5UAZ3   A0A0P6GJR3   A0A0N8DE38   A0A0P5Y055   A0A0P5X813   A0A0P5XUP8   A0A0P5YNS9   A0A162QRA1   A0A0P5XL26   A0A0P5Y2L0   A0A0N8A576   A0A0P5WP50   A0A0P5MXS5   A0A0P5BMC7   A0A0P5V0B5   A0A0P5Z7Y2   A0A0P6E3A7   A0A0P5X120   A0A0P6HUV1   A0A0P5E3J3   A0A195ECY0   A0A0P6EID0   A0A0P5UYZ4   A0A158NXS0   A0A0P5KKG2   A0A139WEE1   A0A151WMN1   A0A182PGK5   A0A210PEG6   A0A0P5I7D4   A0A0P5E440   A0A0P5CYJ3   A0A0P4YDK7   A0A0P5X901   A0A0P5UNV0   A0A0P5W3J8   A0A1Z5LER5   A0A0P5TR24   A0A0P4Z558   A0A0P5MS98   A0A0P5TRY0   B3P8F6   B3LY63   A0A0P6EF37   A0A293LVV1   A0A0P5UUQ5   Q7PXX9   K7IX35  

PDB

5LVX     E-value=8.72917e-65,     Score=626

KEGG

101741392    K01201 glucosylceramidase [EC:3.2.1.45] | (RefSeq) glucosylceramidase-like

PATHWAY

00511    Other glycan degradation - Bombyx mori (domestic silkworm)
00600    Sphingolipid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04142    Lysosome - Bombyx mori (domestic silkworm)

GO

GO:0004348   GO:0006665   GO:0016021   GO:0006680   GO:0016787   GO:0008340   GO:0007613   GO:0005623   GO:0008344   GO:0070050   GO:0034620   GO:0005975   GO:0016020   GO:0005524   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR11069  

Length:

354

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01646

Exp number, first 60 AAs:

0.00019

Total prob of N-in:

0.01890

outside

1  -  354

 

 

Pi

29.911693

Theta

30.152616

Tajima's D

0.09441

CLR

0.42138

CSRT

0.390980450977451

Interpretation

Uncertain