Gene

KWMTBOMO08009

Pre Gene Modal

BGIBMGA001018

Annotation

PREDICTED:_epoxide_hydrolase_3-like_[Papilio_xuthus]

Location

Bomo_Chr13(+):12218754-12234599      View in EpiBrowser

Full name

Epoxide hydrolase 4      

Alternative Name

Abhydrolase domain-containing protein 7
Epoxide hydrolase-related protein

Location in the cell

PlasmaMembrane   Reliability : 2.235

CDS

ATGAAGCAATATATTTATCGGTTTGTCGTAACGAACGCGTTAACGCTGTTTTACGGCTTTCTAACTTTAGTGATCTTTCTTCGGAATTATGTAAGGAACCCGTTCCGAAATCCATGGGAGCAGAAGTTGAGGCTTGTCCCGCCCGCGCCTCTATCCGACCCCAAGTATGGAATTCACAAGAATATCAAAGTTAATGGCATAAAACTACATTACGTTGAAAGCGGCGACCCTTCGAAGCCTTTAATGATTTTTCTACATGGTTTTCCTGAATTCTGGTATTCATGGAGATACCAAATTTTGGAATTTAAGAAAGATTATTGGTGCATAGCCGTTGACATGCGAGGATACGGAGATTCCGAAAGAGTTGAAGATGTCTCCGCCTACAAGTTAAATCTGCTCATTGACGACATCAAATATTTAGTTAAGGAGCTGGGTCGTGAGAAGTGCATTTTAGTCTCGCATGACTGGGGAGGTGCGATAGCGAATGCTATACGAAATTCGTACCCCGAAATAGTCAGCGCATTGATTATGTTAGCCAGCATGTCAACCGCAGCTTCTATTCACGAAATATGGAACAATTCAAAGCAGTTCTTAATGTCTTGGTACTTCTTCCTGTTTCGTCTACCTTGGCTGCCAGAGCAGTTTGTCTCAATGAACGACCTTGAGATACATGATAAGATATTACTTGTTCCTGGCAACACGTATGTCGACAAGCAAGATGTCGAATGTTACAAGTACTGGTTTTGTAAGCCTTATGCTCTGACTCCACCCATTAATTACTACCGTGCCAACTTCGATTATATCGCAAATGATAAATATTACAAAGATAATGTTCCAATGCTAGTCGTACACGCTGCCAAAGATTTGTACATCAACAAAACAGTTCTGGAAGCTATGAAGAAACAATACGAATACATCGAAACTGTAATAGTCGACGGTGTCGGACATGCACTACAGCAACACGATCCAGACAGAATCAATAAAATAATTCGAGATTTTCTAGCCAAGAACAATCTATAA

Protein

MKQYIYRFVVTNALTLFYGFLTLVIFLRNYVRNPFRNPWEQKLRLVPPAPLSDPKYGIHKNIKVNGIKLHYVESGDPSKPLMIFLHGFPEFWYSWRYQILEFKKDYWCIAVDMRGYGDSERVEDVSAYKLNLLIDDIKYLVKELGREKCILVSHDWGGAIANAIRNSYPEIVSALIMLASMSTAASIHEIWNNSKQFLMSWYFFLFRLPWLPEQFVSMNDLEIHDKILLVPGNTYVDKQDVECYKYWFCKPYALTPPINYYRANFDYIANDKYYKDNVPMLVVHAAKDLYINKTVLEAMKKQYEYIETVIVDGVGHALQQHDPDRINKIIRDFLAKNNL

Similarity

Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.

Keywords

Complete proteome   Hydrolase   Membrane   Polymorphism   Reference proteome   Signal-anchor   Transmembrane   Transmembrane helix  

Feature

chain  Epoxide hydrolase 4
sequence variant  In dbSNP:rs17854127.

Uniprot

H9IUT8   A0A2H1V482   A0A2A4J813   A0A212FP09   A0A3S2P035   A0A194Q6F7   + More
A0A194R4S5   A0A182JK48   A0A182GRL0   Q176I8   A0A182G6C7   A0A1B6FEJ8   A0A194R3X9   A0A182SM00   A0A182QH98   U5EGL8   Q7PZL6   A0A182MDM7   A0A182U932   A0A182USP8   A0A2M3Z6C4   A0A2M4BT77   A0A2M3Z5K0   A0A2M3Z5J1   A0A2M4BT67   A0A023EQ13   W5JL78   A0A2M4A5K2   B0XJ28   A0A182W230   A0A182YBN1   A0A1Q3FBJ6   A0A182RKG1   A0A2J7R397   A0A182XJM6   A0A067RU58   A0A182FTQ6   A0A182NZY4   A0A182GSE2   Q176I7   A0A067RWQ5   A0A2J7R3C2   A0A336LSA0   B0XJ30   A0A182GRK8   B0WFT3   A0A146KN80   V4BCL3   A0A2J7R388   Q176J0   A0A1B0GL84   A0A067RMS1   A0A1S3HRG0   A0A226ELK1   A0A1B6L515   B0WFT1   A0A1B6JJR5   A0A1L8DYW4   A0A1L8DZB6   A0A0B6YQU2   A0A1B6E5K7   V4BHS9   A0A1J1IC92   A0A1X7U8B3   A0A2C9K8K1   A0A2P8ZI48   A0A0B7B8T7   A0A2M4A7L1   A0A3R7PHY9   A0A0K8SZ58   A0A0A9YNM3   R4G3W1   G3WEW4   T1IWN7   A0A1E1X894   A0A1W0W9R3   A0A0B7BIC4   A0A131Y1H6   A0A099ZQ59   A0A0B6ZKI8   A0A1S3J531   W4Z450   F7G315   A0A0B7B4K1   A0A1V4JYW0   K7F3S7   H2N6S6   A0A0K8RRD7   H2ZVN0   A0A2K5R6M7   F7D2S6   A0A2K6U1F0   G3QD12   G1RHG6   Q8IUS5   A0A0B7B2E3   A0A0Q3MI06   R7TRZ4   A0A2J8T701  

EC Number

3.3.-.-

Pubmed

19121390    22118469    26354079    26483478    17510324    12364791    + More
14747013    17210077    24945155    20920257    23761445    25244985    24845553    26823975    23254933    15562597    29403074    25401762    21709235    28503490    17495919    17381049    9215903    25243066    22398555    14702039    15489334   

EMBL

BABH01000547    BABH01000548    ODYU01000577    SOQ35586.1    NWSH01002453    PCG68267.1    + More
AGBW02004200    OWR55465.1    RSAL01000074    RVE48959.1    KQ459439    KPJ00959.1    KQ460761    KPJ12514.1    JXUM01016362    KQ560456    KXJ82329.1    CH477386    EAT42095.1    JXUM01147659    JXUM01147660    JXUM01147661    KQ570412    KXJ68369.1    GECZ01021152    JAS48617.1    KPJ12513.1    AXCN02001144    GANO01003390    JAB56481.1    AAAB01008986    EAA00354.3    AXCM01000173    GGFM01003325    MBW24076.1    GGFJ01007052    MBW56193.1    GGFM01003041    MBW23792.1    GGFM01003038    MBW23789.1    GGFJ01007053    MBW56194.1    GAPW01002468    JAC11130.1    ADMH02001207    ETN63670.1    GGFK01002773    MBW36094.1    DS233427    EDS29923.1    GFDL01010099    JAV24946.1    NEVH01007822    PNF35321.1    KK852417    KDR24345.1    JXUM01084364    KQ563433    KXJ73838.1    EAT42096.1    KDR24344.1    PNF35320.1    UFQT01000147    SSX20892.1    EDS29925.1    JXUM01016357    KXJ82327.1    DS231920    EDS26427.1    GDHC01021090    JAP97538.1    KB199650    ESP05421.1    PNF35311.1    EAT42093.1    AJWK01034520    KDR24343.1    LNIX01000003    OXA58563.1    GEBQ01021169    GEBQ01006444    JAT18808.1    JAT33533.1    EDS26425.1    GECU01008354    JAS99352.1    GFDF01002458    JAV11626.1    GFDF01002459    JAV11625.1    HACG01011620    HACG01011621    HACG01011622    CEK58485.1    CEK58486.1    CEK58487.1    GEDC01004087    JAS33211.1    ESP05422.1    CVRI01000044    CRK96598.1    PYGN01000050    PSN56166.1    HACG01042462    CEK89327.1    GGFK01003411    MBW36732.1    QCYY01002845    ROT67142.1    GBRD01007312    JAG58509.1    GBHO01010363    JAG33241.1    ACPB03009260    GAHY01001321    JAA76189.1    AEFK01152852    AEFK01152853    JH431625    GFAC01003744    JAT95444.1    MTYJ01000159    OQV11892.1    HACG01045196    CEK92061.1    GEFM01003448    JAP72348.1    KL895887    KGL82920.1    HACG01022279    HACG01022280    CEK69144.1    CEK69145.1    AAGJ04074142    HACG01040165    CEK87030.1    LSYS01005497    OPJ77331.1    AGCU01191113    AGCU01191114    AGCU01191115    AGCU01191116    AGCU01191117    AGCU01191118    ABGA01060702    ABGA01060703    NDHI03003423    PNJ55387.1    GADI01000161    JAA73647.1    AFYH01117506    AFYH01117507    AFYH01117508    AFYH01117509    AFYH01117510    AFYH01117511    AFYH01117512    GAMT01006025    GAMR01010037    GAMP01003144    JAB05836.1    JAB23895.1    JAB49611.1    CABD030004544    ADFV01189711    ADFV01189712    AK074822    BC041475    HACG01040167    CEK87032.1    LMAW01002002    KQK82111.1    AMQN01011323    KB308827    ELT96409.1    NDHI03003519    PNJ28817.1    PNJ28819.1    PNJ28820.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000283053    UP000053268    UP000053240    + More
UP000075880    UP000069940    UP000249989    UP000008820    UP000075901    UP000075886    UP000007062    UP000075883    UP000075902    UP000075903    UP000000673    UP000002320    UP000075920    UP000076408    UP000075900    UP000235965    UP000076407    UP000027135    UP000069272    UP000075885    UP000030746    UP000092461    UP000085678    UP000198287    UP000183832    UP000007879    UP000076420    UP000245037    UP000283509    UP000015103    UP000007648    UP000053641    UP000007110    UP000002280    UP000190648    UP000007267    UP000001595    UP000008672    UP000233040    UP000008225    UP000233220    UP000001519    UP000001073    UP000005640    UP000051836    UP000014760   

PRIDE

H9IUT8    Q8IUS5   

Pfam

PF12697   Abhydrolase_6        + More
PF00561   Abhydrolase_1
PF00149   Metallophos
PF02872   5_nucleotid_C

Interpro

IPR000639   Epox_hydrolase-like        + More
IPR000073   AB_hydrolase_1       
IPR029058   AB_hydrolase       
IPR001611   Leu-rich_rpt       
IPR032675   LRR_dom_sf       
IPR006179   5_nucleotidase/apyrase       
IPR029052   Metallo-depent_PP-like       
IPR008334   5'-Nucleotdase_C       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR036907   5'-Nucleotdase_C_sf       
IPR006146   5'-Nucleotdase_CS       

SUPFAM

SSF53474   SSF53474        + More
SSF55816   SSF55816       

Gene 3D

3.40.50.1820     3.80.10.10     3.60.21.10     3.90.780.10    

ProteinModelPortal

H9IUT8   A0A2H1V482   A0A2A4J813   A0A212FP09   A0A3S2P035   A0A194Q6F7   + More
A0A194R4S5   A0A182JK48   A0A182GRL0   Q176I8   A0A182G6C7   A0A1B6FEJ8   A0A194R3X9   A0A182SM00   A0A182QH98   U5EGL8   Q7PZL6   A0A182MDM7   A0A182U932   A0A182USP8   A0A2M3Z6C4   A0A2M4BT77   A0A2M3Z5K0   A0A2M3Z5J1   A0A2M4BT67   A0A023EQ13   W5JL78   A0A2M4A5K2   B0XJ28   A0A182W230   A0A182YBN1   A0A1Q3FBJ6   A0A182RKG1   A0A2J7R397   A0A182XJM6   A0A067RU58   A0A182FTQ6   A0A182NZY4   A0A182GSE2   Q176I7   A0A067RWQ5   A0A2J7R3C2   A0A336LSA0   B0XJ30   A0A182GRK8   B0WFT3   A0A146KN80   V4BCL3   A0A2J7R388   Q176J0   A0A1B0GL84   A0A067RMS1   A0A1S3HRG0   A0A226ELK1   A0A1B6L515   B0WFT1   A0A1B6JJR5   A0A1L8DYW4   A0A1L8DZB6   A0A0B6YQU2   A0A1B6E5K7   V4BHS9   A0A1J1IC92   A0A1X7U8B3   A0A2C9K8K1   A0A2P8ZI48   A0A0B7B8T7   A0A2M4A7L1   A0A3R7PHY9   A0A0K8SZ58   A0A0A9YNM3   R4G3W1   G3WEW4   T1IWN7   A0A1E1X894   A0A1W0W9R3   A0A0B7BIC4   A0A131Y1H6   A0A099ZQ59   A0A0B6ZKI8   A0A1S3J531   W4Z450   F7G315   A0A0B7B4K1   A0A1V4JYW0   K7F3S7   H2N6S6   A0A0K8RRD7   H2ZVN0   A0A2K5R6M7   F7D2S6   A0A2K6U1F0   G3QD12   G1RHG6   Q8IUS5   A0A0B7B2E3   A0A0Q3MI06   R7TRZ4   A0A2J8T701  

PDB

5NG7     E-value=3.80022e-39,     Score=405

KEGG

101742214    K22369 epoxide hydrolase 4 [EC:3.3.-.-] | (RefSeq) epoxide hydrolase 4-like

GO

GO:0003824   GO:0016021   GO:0016787   GO:0000166   GO:0046872   GO:0016788   GO:0009166   GO:0006231   GO:0006468   GO:0005509   GO:0016020   GO:0005524   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR11575  

Subcellular location

Membrane  

Length:

339

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

25.66235

Exp number, first 60 AAs:

22.63307

Total prob of N-in:

0.72398

POSSIBLE N-term signal

sequence

inside

1  -  4

TMhelix

5  -  27

outside

28  -  339

 

 

Pi

221.074281

Theta

168.449168

Tajima's D

1.216467

CLR

0.037554

CSRT

0.71746412679366

Interpretation

Uncertain