Gene

KWMTBOMO07975

Pre Gene Modal

BGIBMGA001001

Annotation

achaete-scute-like_protein_[Bombyx_mori]

Location

Bomo_Chr13(+):11629869-11631717      View in EpiBrowser

Full name

Achaete-scute complex protein T3      

Alternative Name

Protein lethal of scute

Transcription factor

bHLH

Location in the cell

Nuclear   Reliability : 4.07

CDS

ATGGCGGCGATTCACGGCTATCAAAATCTGGGTGTCGATCAAAAACTGACGCACCTGCAAACTCCTGCACCGAGGAGACTGGCACCGGCTCCAGTTGACACGACCCGCTGCAAGAAGAGATCTTATCTTCATCAGCCGTACCCAACCCAGCCTGCTTCAGTGGCCCGGAGGAATGCGCGAGAGCGGAATAGAGTGAAACAAGTCAACAACGGATTTGCGGCACTCCGACAACATATTCCCTCGGCTGTGACGGCTGCTCTTGCAGGCGGCAGAGGTTCCTCCAGAAAATTAAGCAAGGTAGATACTTTACGGCTAGCAGTAGAGTACATTAAAAGCTTAAAGAGGCTTTTAGATGAAAGCGATGATGGATGTTCAGATACCCAATTAGGGCTTGGATTATCTACGACAGGCTCGCAAACGCCACCATCATCGGAAGAATCTCATTCTCCAGCCCCATCATTCGTGTCTGAAAGTTCTGCAGGGCCTAATTGTCATGACGTATACGATGCCTACGAACCCATGAGTCCAGAAGACGAGGAACTACTTGACGTCATATCGTGGTGGCAACAACAGTGA

Protein

MAAIHGYQNLGVDQKLTHLQTPAPRRLAPAPVDTTRCKKRSYLHQPYPTQPASVARRNARERNRVKQVNNGFAALRQHIPSAVTAALAGGRGSSRKLSKVDTLRLAVEYIKSLKRLLDESDDGCSDTQLGLGLSTTGSQTPPSSEESHSPAPSFVSESSAGPNCHDVYDAYEPMSPEDEELLDVISWWQQQ

Subunit

Efficient DNA binding requires dimerization with another bHLH protein.

Miscellaneous

AS-C proteins are expressed first earlier in ectoderm and then in the internalized neuroblasts, while T8 is expressed in presumptive neural precursors, once they have segregated from the ectoderm.

Keywords

Complete proteome   Developmental protein   Differentiation   DNA-binding   Neurogenesis   Reference proteome  

Feature

chain  Achaete-scute complex protein T3

Uniprot

H9IUS1   Q2I1Z2   A0A2A4J581   A0A194Q8M1   A0A212ENE2   A0A194R5N2   + More
A0A0H3UYS2   A0A0L7KP59   T1HC65   A0A2R7W5Z6   A0A0K8T2Y0   A0A154PKB8   A0A310SMU7   A0A195CD83   A0A0N0BD42   A0A2P8YB04   Q174P2   N6TZG9   U4UNX8   Q6VXY1   A0A185RUN4   Q9U910   Q9GNL5   A0A0F7IKF2   O76488   A0A1W4XHC9   O77032   Q16Z21   P09774   Q0H6N8   A0A194R9L4   O77030   A0A182GS63   A0A0L7KWQ5   A0A212ENG6   A6N867   A0A2A4J920   A0A0M4F949   A0A1S3CTP3   A0A2H1VLD1   Q6VYM9   A0A2A4J938   T1GYJ3   A0A194Q8Y4   A0A2H1VME4   A0A0H3UYT4   A0A1I8Q504   Q6VYN2   A0A1I8MJI8   A6N868   A0A1A9XRU2   B3MSE1   A0A1B0AK79   A0A1A9WPI6   H9IUS0   A0A1B0FFB8   A0A194R4E4   A0A0L0C4V5   Q8WQQ6   A0A1A9UUP6   A0A194QA55   A0A1W4V7V8   A0A0K3CRL9   A0A0N8JY66   A0A0Q9WQT3  

Pubmed

19121390    16773336    26354079    22118469    26227816    26823975    + More
29403074    17510324    23537049    12900453    25995006    10545459    17994087    18057021    11264413    9663389    9611206    2461300    8076513    10731132    12537572    10731137    12537569    16547109    17550304    26483478    18321391    14704182    25315136    26108605    11830558    23552491   

EMBL

BABH01000596    DQ350889    DQ350890    ABC84346.1    ABC84347.1    NWSH01003306    + More
PCG66590.1    KQ459299    KPJ01873.1    AGBW02013662    OWR43025.1    KQ460761    KPJ12545.1    KJ158244    AIZ67914.1    JTDY01008101    KOB64739.1    ACPB03007141    KK854372    PTY15157.1    GBRD01005924    GDHC01005821    JAG59897.1    JAQ12808.1    KQ434946    KZC12321.1    KQ761046    OAD58328.1    KQ978009    KYM98171.1    KQ435878    KOX69918.1    PYGN01000741    PSN41442.1    CH477407    EAT41556.1    APGK01002009    KB734570    ENN83543.1    KB632299    ERL91735.1    AY321476    AAQ23386.1    KM244736    AKC02108.1    AB017570    CH954183    BAA86616.1    EDV45356.1    AB032461    BAB20411.1    KP147933    AKG92770.1    AF071498    AAC24714.1    AB005802    CM000366    BAA33213.1    EDX16748.1    CH477503    EAT39888.1    X12549    X71806    AE014298    AL024453    AY121693    DQ184989    ABB22065.1    KPJ12546.1    AB005800    CM000162    BAA33211.1    EDX00778.1    JXUM01085146    KQ563483    KXJ73762.1    JTDY01004860    KOB67667.1    OWR43023.1    BABH01000604    EF620927    ABR20839.1    NWSH01002585    PCG67912.1    KP245732    ALC76152.1    ODYU01003190    SOQ41611.1    AY319382    AAQ82735.1    PCG67913.1    CAQQ02189294    KPJ01874.1    SOQ41612.1    KJ158243    AIZ67913.1    AY319379    AAQ82732.1    EF620928    ABR20840.1    CH902622    EDV34696.2    BABH01000608    CCAG010007179    KPJ12547.1    JRES01000915    KNC27271.1    AY061876    AAL32066.1    KPJ01875.1    LN877230    CTR11686.1    JARO02006144    KPP65681.1    CH940655    KRF82640.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000053240    UP000037510    + More
UP000015103    UP000076502    UP000078542    UP000053105    UP000245037    UP000008820    UP000019118    UP000030742    UP000008711    UP000192223    UP000000304    UP000000803    UP000002282    UP000069940    UP000249989    UP000079169    UP000015102    UP000095300    UP000095301    UP000092443    UP000007801    UP000092445    UP000091820    UP000092444    UP000037069    UP000078200    UP000192221    UP000034805    UP000008792   

PRIDE

H9IUS1    Q2I1Z2    P09774    A6N867    A6N868    H9IUS0    + More

Pfam

PF00010   HLH

Interpro

IPR011598   bHLH_dom        + More
IPR036638   HLH_DNA-bd_sf       
IPR015660   MASH1/Ascl1a-like       

SUPFAM

SSF47459   SSF47459       

Gene 3D

4.10.280.10    

CDD

cd00083  HLH

ProteinModelPortal

H9IUS1   Q2I1Z2   A0A2A4J581   A0A194Q8M1   A0A212ENE2   A0A194R5N2   + More
A0A0H3UYS2   A0A0L7KP59   T1HC65   A0A2R7W5Z6   A0A0K8T2Y0   A0A154PKB8   A0A310SMU7   A0A195CD83   A0A0N0BD42   A0A2P8YB04   Q174P2   N6TZG9   U4UNX8   Q6VXY1   A0A185RUN4   Q9U910   Q9GNL5   A0A0F7IKF2   O76488   A0A1W4XHC9   O77032   Q16Z21   P09774   Q0H6N8   A0A194R9L4   O77030   A0A182GS63   A0A0L7KWQ5   A0A212ENG6   A6N867   A0A2A4J920   A0A0M4F949   A0A1S3CTP3   A0A2H1VLD1   Q6VYM9   A0A2A4J938   T1GYJ3   A0A194Q8Y4   A0A2H1VME4   A0A0H3UYT4   A0A1I8Q504   Q6VYN2   A0A1I8MJI8   A6N868   A0A1A9XRU2   B3MSE1   A0A1B0AK79   A0A1A9WPI6   H9IUS0   A0A1B0FFB8   A0A194R4E4   A0A0L0C4V5   Q8WQQ6   A0A1A9UUP6   A0A194QA55   A0A1W4V7V8   A0A0K3CRL9   A0A0N8JY66   A0A0Q9WQT3  

PDB

2YPB     E-value=0.0413966,     Score=82

KEGG

692996    K09067 achaete-scute complex protein | (RefSeq) Ash1; achaete-scute-like protein

GO

GO:0003677   GO:0046983   GO:0006357   GO:0045944   GO:0061331   GO:0046982   GO:0007400   GO:0005667   GO:0000977   GO:0003700   GO:0061382   GO:0045893   GO:0043565   GO:0007422   GO:0007518   GO:0007417   GO:0007419   GO:0005643   GO:0016616   GO:0016491   GO:0019752   GO:0006427   GO:0016020   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR13935  

Length:

191

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02569

Exp number, first 60 AAs:

0

Total prob of N-in:

0.09938

outside

1  -  191

 

 

Pi

131.975271

Theta

122.813104

Tajima's D

-0.496277

CLR

11.32066

CSRT

0.241737913104345

Interpretation

Uncertain