Gene

KWMTBOMO07974

Pre Gene Modal

BGIBMGA001148

Annotation

achaete-scute-like_protein_ASH2_[Bombyx_mori]

Location

Bomo_Chr13(-):11504641-11505858      View in EpiBrowser

Full name

Achaete-scute complex protein T3      

Alternative Name

Protein lethal of scute

Transcription factor

bHLH

Location in the cell

Nuclear   Reliability : 4.235

CDS

ATGCTCCAAGAAATCCAGCTAGTTCAAGGTCAGACGAATTACGTGGTCGTTTCTTCCGGATATCCTTCGAATACATTGAATAAATCATCTTTAGAGAAACGAAATGTTGCTATAGCTCCAGCGCCTGAGAAAAATTACGTCACACACGACACTCCACCGAATCTACACTACAGGAAAAAGGTGCATTTCAGAACTAATCCGTACACTGGACCACAGGCTGCGTCAATAGCGAGACGTAATGCACGGGAACGAAATCGCGTAAAACAAGTGAATGATGGATTCAACGCACTTCGCCGTCACCTGCCGGCTTCTGTCGTGGCAGCTCTGTCCGGTGGCGCCAGACGAGGTTCGTCAGGGAAGAAACTTAGCAAAGTCGACACATTACGGATGGTTGTTGAATATATAAGGTACCTTCAGCAGTTATTAGACGAAAGTGATGCCGCATTAGGTATTACGCGTGATCAAGAAAATCGGGAAAATATTCCAAGCAATAACTCAGTTCAGCCGATGACTTCTATTGACATGGATGACGGGTTTTTCTACGGAAGTGGATCACCTTGTTCAGAGAAGGCAGATTCGCCAGCTCCTTCGGAATGTTCTTCGGGTGTGTCTTCGGCGTATTCGGCTGTCGATCGTTACGAGGTTACTACGCAGCAACAAATGGGATCAATGGATGAAGAAGAACTCTTAGACGTCATTTCATGGTGGCAACAAAAATAG

Protein

MLQEIQLVQGQTNYVVVSSGYPSNTLNKSSLEKRNVAIAPAPEKNYVTHDTPPNLHYRKKVHFRTNPYTGPQAASIARRNARERNRVKQVNDGFNALRRHLPASVVAALSGGARRGSSGKKLSKVDTLRMVVEYIRYLQQLLDESDAALGITRDQENRENIPSNNSVQPMTSIDMDDGFFYGSGSPCSEKADSPAPSECSSGVSSAYSAVDRYEVTTQQQMGSMDEEELLDVISWWQQK

Subunit

Efficient DNA binding requires dimerization with another bHLH protein.

Miscellaneous

AS-C proteins are expressed first earlier in ectoderm and then in the internalized neuroblasts, while T8 is expressed in presumptive neural precursors, once they have segregated from the ectoderm.

Keywords

Complete proteome   Developmental protein   Differentiation   DNA-binding   Neurogenesis   Reference proteome  

Feature

chain  Achaete-scute complex protein T3

Uniprot

A6N867   A0A2A4J938   A0A2H1VLD1   O76488   A0A0L7KWQ5   A0A194Q8Y4   + More
A0A212ENF6   A0A194R9L4   A0A0H3UYT4   A0A2H1VME4   A0A2A4J920   A0A0M4F949   A0A194QA55   A0A194R4E4   H9IUS0   A6N868   A0A212ENG6   Q16Z21   A0A182GS63   A0A0P6FRG6   A0A2P8YB04   A0A194Q8M1   A0A336KPN9   U4UNX8   A0A2A4J581   Q2I1Z2   H9IUS1   A0A2R7W5Z6   A0A212ENE2   A0A0N0BD42   A0A154PKB8   A0A1S4FJ51   Q16Z23   A0A310SMU7   A0A0H3UYS2   Q174P2   A0A0M4F923   A0A0L7KP59   N6TZG9   A0A0L7R3G1   A0A067R5E0   T1HC65   A3E0V8   E9IF61   A0A226EPU9   A0A1S3CTP3   Q6VYM9   Q8WQQ6   A0A0K8T2Y0   A0A1W4XHC9   A0A194R5N2   E0VXK7   B3MSE1   P09774   A0A0F7IKF2   A0A195CD83   O77032   Q9GNL5   Q9U910  

Pubmed

18321391    19121390    9663389    26227816    26354079    22118469    + More
17510324    26483478    29403074    23537049    16773336    24845553    19322682    21282665    14704182    11830558    26823975    20566863    17994087    2461300    8076513    10731132    12537572    10731137    12537569    9611206    11264413    10545459    18057021   

EMBL

BABH01000604    EF620927    ABR20839.1    NWSH01002585    PCG67913.1    ODYU01003190    + More
SOQ41611.1    AF071498    AAC24714.1    JTDY01004860    KOB67667.1    KQ459299    KPJ01874.1    AGBW02013662    OWR43024.1    KQ460761    KPJ12546.1    KJ158243    AIZ67913.1    SOQ41612.1    PCG67912.1    KP245732    ALC76152.1    KPJ01875.1    KPJ12547.1    BABH01000608    EF620928    ABR20840.1    OWR43023.1    CH477503    EAT39888.1    JXUM01085146    KQ563483    KXJ73762.1    GDIQ01045359    JAN49378.1    PYGN01000741    PSN41442.1    KPJ01873.1    UFQS01000677    UFQT01000677    SSX06121.1    SSX26477.1    KB632299    ERL91735.1    NWSH01003306    PCG66590.1    DQ350889    DQ350890    ABC84346.1    ABC84347.1    BABH01000596    KK854372    PTY15157.1    OWR43025.1    KQ435878    KOX69918.1    KQ434946    KZC12321.1    EAT39886.1    KQ761046    OAD58328.1    KJ158244    AIZ67914.1    CH477407    EAT41556.1    CP012528    ALC48632.1    JTDY01008101    KOB64739.1    APGK01002009    KB734570    ENN83543.1    KQ414663    KOC65425.1    KK852878    KDR14510.1    ACPB03007141    DQ489559    ABF50840.2    GL762758    EFZ20812.1    LNIX01000002    OXA59177.1    AY319382    AAQ82735.1    AY061876    AAL32066.1    GBRD01005924    GDHC01005821    JAG59897.1    JAQ12808.1    KPJ12545.1    DS235833    EEB18113.1    CH902622    EDV34696.2    X12549    X71806    AE014298    AL024453    AY121693    KP147933    AKG92770.1    KQ978009    KYM98171.1    AB005802    CM000366    BAA33213.1    EDX16748.1    AB032461    BAB20411.1    AB017570    CH954183    BAA86616.1    EDV45356.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053268    UP000007151    UP000053240    + More
UP000008820    UP000069940    UP000249989    UP000245037    UP000030742    UP000053105    UP000076502    UP000092553    UP000019118    UP000053825    UP000027135    UP000015103    UP000198287    UP000079169    UP000192223    UP000009046    UP000007801    UP000000803    UP000078542    UP000000304    UP000008711   

PRIDE

A6N867    H9IUS0    A6N868    Q2I1Z2    H9IUS1    P09774    + More

Pfam

PF00010   HLH

Interpro

IPR036638   HLH_DNA-bd_sf        + More
IPR011598   bHLH_dom       
IPR015660   MASH1/Ascl1a-like       

SUPFAM

SSF47459   SSF47459       

Gene 3D

4.10.280.10    

CDD

cd00083  HLH

ProteinModelPortal

A6N867   A0A2A4J938   A0A2H1VLD1   O76488   A0A0L7KWQ5   A0A194Q8Y4   + More
A0A212ENF6   A0A194R9L4   A0A0H3UYT4   A0A2H1VME4   A0A2A4J920   A0A0M4F949   A0A194QA55   A0A194R4E4   H9IUS0   A6N868   A0A212ENG6   Q16Z21   A0A182GS63   A0A0P6FRG6   A0A2P8YB04   A0A194Q8M1   A0A336KPN9   U4UNX8   A0A2A4J581   Q2I1Z2   H9IUS1   A0A2R7W5Z6   A0A212ENE2   A0A0N0BD42   A0A154PKB8   A0A1S4FJ51   Q16Z23   A0A310SMU7   A0A0H3UYS2   Q174P2   A0A0M4F923   A0A0L7KP59   N6TZG9   A0A0L7R3G1   A0A067R5E0   T1HC65   A3E0V8   E9IF61   A0A226EPU9   A0A1S3CTP3   Q6VYM9   Q8WQQ6   A0A0K8T2Y0   A0A1W4XHC9   A0A194R5N2   E0VXK7   B3MSE1   P09774   A0A0F7IKF2   A0A195CD83   O77032   Q9GNL5   Q9U910  

KEGG

100125603    K09067 achaete-scute complex protein | (RefSeq) Ash2; achaete-scute-like protein ASH2

GO

GO:0006357   GO:0046983   GO:0003677   GO:0061382   GO:0005667   GO:0003700   GO:0000977   GO:0007400   GO:0046982   GO:0061331   GO:0045944   GO:0045893   GO:0043565   GO:0007422   GO:0007518   GO:0007417   GO:0007419   GO:0005643   GO:0016616   GO:0016491   GO:0019752   GO:0006427   GO:0016020   GO:0006412   GO:0016876   GO:0043039  

PANTHER

PTHR13935  

Length:

239

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00272

Exp number, first 60 AAs:

0.00102

Total prob of N-in:

0.02601

outside

1  -  239

 

 

Pi

157.49746

Theta

177.033801

Tajima's D

-0.30401

CLR

1.001496

CSRT

0.287035648217589

Interpretation

Uncertain