Gene

KWMTBOMO07965

Pre Gene Modal

BGIBMGA000998

Annotation

PREDICTED:_uncharacterized_protein_LOC106713539_[Papilio_machaon]

Location

Bomo_Chr13(+):11255440-11258241      View in EpiBrowser

Full name

Protein quiver      

Alternative Name

Protein sleepless

Location in the cell

Extracellular   Reliability : 2.532 PlasmaMembrane   Reliability : 1.922

CDS

ATGAAGCACTACATTGTATTTTTGTTAATGTTAGGAGCTAATGAATGTTTGGCTACATGGTGCTACCAGTGTACAGCGGCTACTCCTGGTTGTAATGAGCCTTTTAATTGGCGTGGAATGGGATATCTTGGCAATCCATGTCCCGAAAGTGAGGATGTTTGTGTTAAACTTATTGAAAGGAAAGGAGCACAAGAAGTTATTACAAGGGATTGTTTAAGCAATTTTAGAGCTTTCCGAACCGATATTCCTGCTGATACATATGAAGGATGTCGTCCTGCTGCTAAAGATTTAAATCTTGCTCATTATGTCAATAATAGTATAAAAGAGATTGATGTTAAAAGAAATTGGTACGATGAAACCATATGGTGCTTCTGTTTTCTGGACCACCGCTGTAACAATGCATCGAATACATTTGTTTCAATAGCGTTGCTAATGTTATCCGGTGCTACTATATTGTTCAACAAAATATTGTTCTGA

Protein

MKHYIVFLLMLGANECLATWCYQCTAATPGCNEPFNWRGMGYLGNPCPESEDVCVKLIERKGAQEVITRDCLSNFRAFRTDIPADTYEGCRPAAKDLNLAHYVNNSIKEIDVKRNWYDETIWCFCFLDHRCNNASNTFVSIALLMLSGATILFNKILF

Description

Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability.

Similarity

Belongs to the quiver family.

Feature

chain  Protein quiver

Uniprot

A0A2H1VW45   A0A1E1WTR7   A0A194R415   A0A0L7L088   S4P4R6   A0A194QA60   + More
A0A212FFF9   A0A2A4JJR0   A0A2M4C1H1   A0A2M4C192   T1E9X4   A0A2M3Z751   A0A2M3ZE51   A0A2M3Z6V8   W5JS25   A0A2M4AY16   A0A2M4AXJ7   A0A2M4AXC9   A0A2M4AWQ3   A0A182Y6X1   A0A182WFP1   A0A0K8VJC5   A0A182WYU6   A0A182FLK1   A0A182P0S7   A0A182QX39   A0A182RLM7   A0A182VG76   A0A182MFG5   A7US48   A0A182HY86   A0A182LHD4   A0A1S4H7A6   A0A1J1I499   A0A182UCL0   A0A034VR30   U5EMH4   A0A3F2YW09   A0A0L0BN68   A0A182GSD6   A0A023EGD3   A0A182GJH4   A0A023EHP3   A0A1S4FYC9   B0W2L7   Q16JT0   A0A1Q3FCC1   A0A182SBF9   A0A182J5S7   B3M4B4   A0A1I8Q615   A0A3B0J4Z9   A0A1A9X0B1   A0A336LKM9   B4N4L5   A0A1B0D3G1   B4HAG8   Q2LZ80   B4KUS8   A0A1I8MCQ4   B4LCR4   T1GHF9   A0A151IUB7   B3NGZ6   A0A1B0CE43   B4PFN2   A0A1L8D9K6   A0A151IN56   A0A1B0AEH0   A0A1B0BY91   B4IZB7   A0A1W4X4S8   A0A0M4F1Z0   A0A195F7I1   A0A1B0GBB9   A0A158NYC9   A0A1A9VP42   A0A3L8DXU7   A0A0L7RHA1   A0A2P8YMD6   B4QQA2   R4G374   Q9VTM6   A0A151X886   B4HEX7   A0A232EYU4   A0A1B6CQR7   A0A1W4VVF9   E2A4B4   A0A154PFI8   A0A026X3L7   A0A067RGR4   E2BDF0   K7IZ12   A0A1B6IIT2   A0A1B6MTQ1   A0A1B6GJT0   D6WAX2   A0A310S7H4  

Pubmed

26354079    26227816    23622113    22118469    20920257    23761445    + More
25244985    12364791    20966253    25348373    26108605    26483478    24945155    17510324    17994087    15632085    25315136    17550304    21347285    30249741    29403074    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    28648823    20798317    24508170    24845553    20075255    18362917    19820115   

EMBL

ODYU01004755    SOQ44976.1    GDQN01000853    JAT90201.1    KQ460761    KPJ12553.1    + More
JTDY01004036    KOB68684.1    GAIX01011085    JAA81475.1    KQ459299    KPJ01880.1    AGBW02008828    OWR52471.1    NWSH01001335    PCG71640.1    GGFJ01010008    MBW59149.1    GGFJ01009955    MBW59096.1    GAMD01000922    JAB00669.1    GGFM01003596    MBW24347.1    GGFM01006041    MBW26792.1    GGFM01003490    MBW24241.1    ADMH02000630    ETN65549.1    GGFK01012281    MBW45602.1    GGFK01012111    MBW45432.1    GGFK01012138    MBW45459.1    GGFK01011893    MBW45214.1    GDHF01013318    JAI38996.1    AXCN02001110    AXCM01003816    AAAB01008816    EDO64459.1    APCN01004507    APCN01004508    CVRI01000037    CRK93694.1    GAKP01014018    JAC44934.1    GANO01004477    JAB55394.1    JRES01001603    KNC21555.1    JXUM01084469    KQ563439    KXJ73818.1    GAPW01005192    GAPW01005191    JAC08407.1    JXUM01068210    KQ562488    KXJ75799.1    GAPW01005193    JAC08405.1    DS231827    EDS29325.1    CH477993    EAT34553.1    GFDL01009838    JAV25207.1    CH902618    EDV39384.1    OUUW01000002    SPP76767.1    UFQT01000039    SSX18516.1    CH964095    EDW79089.1    AJVK01023535    CH479240    EDW37566.1    CH379069    EAL29628.2    CH933809    EDW19334.1    CH940647    EDW70956.1    CAQQ02197562    CAQQ02197563    KQ980963    KYN11013.1    CH954178    EDV51453.1    AJWK01008544    CM000159    EDW94181.1    GFDF01011047    JAV03037.1    KQ976963    KYN06779.1    JXJN01022542    CH916366    EDV96672.1    CP012525    ALC45057.1    KQ981768    KYN36024.1    CCAG010022534    ADTU01003755    QOIP01000003    RLU25063.1    KQ414591    KOC70250.1    PYGN01000495    PSN45393.1    CM000363    CM002912    EDX10120.1    KMY99056.1    GAHY01001936    JAA75574.1    AE014296    AY060768    KX531850    AAF50021.1    AAL28316.1    ANY27660.1    KQ982426    KYQ56582.1    CH480815    EDW41146.1    NNAY01001559    OXU23602.1    GEDC01021516    JAS15782.1    GL436621    EFN71724.1    KQ434879    KZC10000.1    KK107013    EZA62867.1    KK852480    KDR22967.1    GL447620    EFN86262.1    GECU01020872    JAS86834.1    GEBQ01000718    JAT39259.1    GECZ01029976    GECZ01007216    GECZ01001445    JAS39793.1    JAS62553.1    JAS68324.1    KQ971312    EEZ97935.1    KQ765809    OAD53797.1   

Proteomes

UP000053240    UP000037510    UP000053268    UP000007151    UP000218220    UP000000673    + More
UP000076408    UP000075920    UP000076407    UP000069272    UP000075885    UP000075886    UP000075900    UP000075903    UP000075883    UP000007062    UP000075840    UP000075882    UP000183832    UP000075902    UP000075884    UP000037069    UP000069940    UP000249989    UP000002320    UP000008820    UP000075901    UP000075880    UP000007801    UP000095300    UP000268350    UP000091820    UP000007798    UP000092462    UP000008744    UP000001819    UP000009192    UP000095301    UP000008792    UP000015102    UP000078492    UP000008711    UP000092461    UP000002282    UP000078542    UP000092445    UP000092460    UP000001070    UP000192223    UP000092553    UP000078541    UP000092444    UP000005205    UP000078200    UP000279307    UP000053825    UP000245037    UP000000304    UP000000803    UP000075809    UP000001292    UP000215335    UP000192221    UP000000311    UP000076502    UP000053097    UP000027135    UP000008237    UP000002358    UP000007266   

PRIDE

Q9VTM6   

Pfam

PF17064   QVR        + More
PF00021   UPAR_LY6

Interpro

IPR031424   QVR        + More
IPR016054   LY6_UPA_recep-like       

ProteinModelPortal

A0A2H1VW45   A0A1E1WTR7   A0A194R415   A0A0L7L088   S4P4R6   A0A194QA60   + More
A0A212FFF9   A0A2A4JJR0   A0A2M4C1H1   A0A2M4C192   T1E9X4   A0A2M3Z751   A0A2M3ZE51   A0A2M3Z6V8   W5JS25   A0A2M4AY16   A0A2M4AXJ7   A0A2M4AXC9   A0A2M4AWQ3   A0A182Y6X1   A0A182WFP1   A0A0K8VJC5   A0A182WYU6   A0A182FLK1   A0A182P0S7   A0A182QX39   A0A182RLM7   A0A182VG76   A0A182MFG5   A7US48   A0A182HY86   A0A182LHD4   A0A1S4H7A6   A0A1J1I499   A0A182UCL0   A0A034VR30   U5EMH4   A0A3F2YW09   A0A0L0BN68   A0A182GSD6   A0A023EGD3   A0A182GJH4   A0A023EHP3   A0A1S4FYC9   B0W2L7   Q16JT0   A0A1Q3FCC1   A0A182SBF9   A0A182J5S7   B3M4B4   A0A1I8Q615   A0A3B0J4Z9   A0A1A9X0B1   A0A336LKM9   B4N4L5   A0A1B0D3G1   B4HAG8   Q2LZ80   B4KUS8   A0A1I8MCQ4   B4LCR4   T1GHF9   A0A151IUB7   B3NGZ6   A0A1B0CE43   B4PFN2   A0A1L8D9K6   A0A151IN56   A0A1B0AEH0   A0A1B0BY91   B4IZB7   A0A1W4X4S8   A0A0M4F1Z0   A0A195F7I1   A0A1B0GBB9   A0A158NYC9   A0A1A9VP42   A0A3L8DXU7   A0A0L7RHA1   A0A2P8YMD6   B4QQA2   R4G374   Q9VTM6   A0A151X886   B4HEX7   A0A232EYU4   A0A1B6CQR7   A0A1W4VVF9   E2A4B4   A0A154PFI8   A0A026X3L7   A0A067RGR4   E2BDF0   K7IZ12   A0A1B6IIT2   A0A1B6MTQ1   A0A1B6GJT0   D6WAX2   A0A310S7H4  

KEGG

101742838    no KO assigned | (RefSeq) uncharacterized LOC101742838

GO

GO:0031225   GO:0032222   GO:0016021   GO:0030431   GO:1903818   GO:0005886   GO:0048511   GO:0034235   GO:0045187   GO:0019991   GO:0035002   GO:0035151   GO:0005918  

Subcellular location

Cell membrane  

SignalP

Position:   1 - 18,         Likelihood:  0.999429

 

 

Length:

158

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

16.61393

Exp number, first 60 AAs:

1.09461

Total prob of N-in:

0.47696

outside

1  -  158

 

 

Pi

128.490717

Theta

136.659105

Tajima's D

-0.37175

CLR

0.307945

CSRT

0.268986550672466

Interpretation

Uncertain