Gene

KWMTBOMO07947

Pre Gene Modal

BGIBMGA001160

Annotation

PREDICTED:_probable_glutamine-dependent_NAD(+)_synthetase_[Papilio_xuthus]

Location

Bomo_Chr13(-):10837362-10840974      View in EpiBrowser

Full name

Glutamine-dependent NAD(+) synthetase      

Alternative Name

NAD(+) synthase [glutamine-hydrolyzing]
NAD(+) synthetase

Location in the cell

Extracellular   Reliability : 1.757

CDS

ATGGTTCTGTCGTATTTGTTCGCGCAGCTAATGCTCTGGGTCCGCGGCAGACCTGGAGGTCTTTTAGTACTGGGATCCTCAAACGTCGACGAAGCCCTGCGAGGCTACATGACCAAGTACGATTGTTCCAGTGCAGATATTAATCCCATCGGTGGAATATCTAAGACTGACCTCAAATCTTTCTTACATTACGCTAAGAATAGATTTTTCTTGCCGTCTCTATCGGAAATTCTAGAAGCACCTCCGACTGCAGAACTCGAGCCATTGGCCGACGGTCAGATAACGCAAACCGACGAACAAGACATGGGTATGACATACGCTGAACTGTCCGAATTCGGAACTTTAAGGAAGACCTATAAATGCGGCCCTTACAGCATGTTCGAGAAACTGGTTCATAAGTGGAGTGATAAATGTACGCCTAAGGAGGTGGCTGAAAAGGTGAAACATTTTTTCCGGTGTTACGCGATCAACAGGCACAAGATGACGGTGCTGACGCCTTCCTACCACGCCGAGACATACAGCCCCGACGACAACCGCTTCGATCTCAGACCTTTCCTATATCGAGTACACTGGAATTGGCAGTTTAAGACCATAGATGACGCTGTCATACAAATGAGCAAGGAAAAGCGTACATCAGTTAGCCGGGTTGGATATGAACAGAGCAAAACAAATCCGAATTCTCCGACTACTACATTGAGTTCGTCGTTCACAAAGAACGACAGACAGGGTGTACTGATATGA

Protein

MVLSYLFAQLMLWVRGRPGGLLVLGSSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSEFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSYHAETYSPDDNRFDLRPFLYRVHWNWQFKTIDDAVIQMSKEKRTSVSRVGYEQSKTNPNSPTTTLSSSFTKNDRQGVLI

Description

Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.

Catalytic Activity

ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)

Similarity

In the C-terminal section; belongs to the NAD synthetase family.

Keywords

ATP-binding   Complete proteome   Ligase   NAD   Nucleotide-binding   Reference proteome  

Feature

chain  Glutamine-dependent NAD(+) synthetase

Uniprot

H9IV80   A0A2H1WA98   A0A2H1VEG0   A0A2A4JVD5   A0A194Q906   A0A3S2M6H4   + More
A0A212EY75   A0A194R9P4   A0A1B6GM02   A0A1B6JE34   D1ZZT1   A0A1B6KSA4   A0A067R837   A0A2J7RRV5   A0A182GI80   A0A034VB33   A0A2J7RRY1   A0A336KV63   A0A0K8W6T7   A0A1J1HV96   U4U8I8   A0A0A1XD61   A0A1W4XJK8   A0A1B6D2S2   A0A1B6D5S3   A0A1Y1KLN7   A0A1Q3G1Q7   A0A2P8ZCY9   T1PKA9   A0A1I8NS65   A0A1Q3G1P3   V9KIP6   Q16E59   Q16Z66   A0A0Q9WMA9   B4M2T6   A0A1S3CXU3   A0A1A8Q9N7   A0A182TC16   B4JL37   A0A0M3QZQ0   A0A1A8A7H0   A0A3B3XLH7   U3I5Q1   A0A1A8L7W3   E0VPD9   U3K2E3   B3MW01   G1MU36   B4L7J5   A0A218URA9   A0A3B0JXK5   F1P4D3   A0A2M4AMM0   A0A091JTW6   A0A1L8GIT4   W4XND2   A0A1A9WFA1   B4Q2E8   A0A2J8S6C0   A0A1W4VGV4   A0A0J7KXT5   B3NWK7   A0A2J8S689   Q29HW0   B4GY71   A0A1A9YF37   A0A1B0C7C8   B4NC89   B1H2T4   A0A099ZVA5   A0A2K6SEN9   A0A182N052   A0A0B4J216   A0A2P4T031   R0L011   A0A2I4AND5   A0A3P4LZZ1   A0A091QST8   A0A087VMG6   G3VZL4   Q5ZMA6   A0A3Q3FHF9   A0A2J8IQ76   C3Y7L9   A0A3Q3JFD8   A0A093NCQ3   A0A226P2X0   G1PXJ9   H0Z4H8   A0A0A0AK77   A0A1B0AHA3   A0A2J8S6A6   A0A1A9VWF6   A0A091VB37   M7B7J6   A0A212DGM2   A0A093QM28   A0A182JFP2   A0A087XA41  

EC Number

6.3.5.1

Pubmed

19121390    26354079    22118469    18362917    19820115    24845553    + More
26483478    25348373    23537049    25830018    28004739    29403074    25315136    24402279    17510324    17994087    18057021    23749191    20566863    20838655    15592404    27762356    17550304    15632085    20431018    16554811    21269460    21709235    15642098    18563158    24621616    21993624    20360741    23624526    29294181   

EMBL

BABH01000660    BABH01000661    BABH01000662    ODYU01007314    SOQ49988.1    ODYU01002110    + More
SOQ39197.1    NWSH01000547    PCG75736.1    KQ459299    KPJ01899.1    RSAL01000021    RVE52525.1    AGBW02011630    OWR46407.1    KQ460761    KPJ12571.1    GECZ01006416    JAS63353.1    GECU01010483    JAS97223.1    KQ971338    EFA01802.1    GEBQ01025660    JAT14317.1    KK852872    KDR14569.1    NEVH01000597    PNF43570.1    JXUM01012269    KQ560350    KXJ82898.1    GAKP01019949    GAKP01019948    GAKP01019947    JAC39005.1    PNF43572.1    UFQS01000799    UFQT01000654    UFQT01000799    SSX06993.1    SSX26169.1    GDHF01005542    GDHF01003534    JAI46772.1    JAI48780.1    CVRI01000019    CRK90414.1    KB632168    ERL89342.1    GBXI01005411    JAD08881.1    GEDC01017318    JAS19980.1    GEDC01016266    JAS21032.1    GEZM01080274    JAV62234.1    GFDL01001298    JAV33747.1    PYGN01000098    PSN54369.1    KA648500    AFP63129.1    GFDL01001311    JAV33734.1    JW865750    AFO98267.1    CH479099    EAT32516.1    CH477497    EAT39937.1    CH940651    KRF82014.1    EDW65111.1    KRF82015.1    HAEG01011498    SBR89914.1    CH916370    EDW00290.1    CP012528    ALC49803.1    HADY01011655    SBP50140.1    ADON01092589    HAEF01003340    SBR40722.1    DS235363    EEB15245.1    AGTO01002176    CH902625    EDV35146.1    CH933813    EDW10989.1    MUZQ01000167    OWK56176.1    OUUW01000003    SPP78086.1    AADN05000685    GGFK01008651    MBW41972.1    KK531466    KFP28160.1    CM004472    OCT83757.1    AAGJ04123609    CM000162    EDX01609.1    NDHI03003604    PNJ16294.1    LBMM01002037    KMQ95367.1    CH954180    EDV47169.1    PNJ16295.1    CH379064    EAL31647.1    CH479197    EDW27727.1    JXJN01028107    JXJN01028108    CH964239    EDW82448.1    AAMC01029887    AAMC01029888    BC161121    AAI61121.1    KL897677    KGL84745.1    AP000867    AP002387    PPHD01014277    POI29711.1    KB743402    EOA98928.1    CYRY02003651    VCW68246.1    KK680580    KFQ12454.1    KL498683    KFO13808.1    AEFK01224255    AJ719478    NBAG03000638    PNI12665.1    GG666489    EEN63847.1    KL224691    KFW62678.1    AWGT02000180    OXB74375.1    AAPE02059498    AAPE02059499    ABQF01001419    KL872041    KGL94317.1    PNJ16296.1    KK422457    KFQ86903.1    KB565340    EMP28143.1    MKHE01000002    OWK17331.1    KL672977    KFW87460.1    AYCK01026215    AYCK01026216    AYCK01026217   

Proteomes

UP000005204    UP000218220    UP000053268    UP000283053    UP000007151    UP000053240    + More
UP000007266    UP000027135    UP000235965    UP000069940    UP000249989    UP000183832    UP000030742    UP000192223    UP000245037    UP000095301    UP000095300    UP000008820    UP000008792    UP000079169    UP000075901    UP000001070    UP000092553    UP000261480    UP000016666    UP000009046    UP000016665    UP000007801    UP000001645    UP000009192    UP000197619    UP000268350    UP000000539    UP000186698    UP000007110    UP000091820    UP000002282    UP000192221    UP000036403    UP000008711    UP000001819    UP000008744    UP000092443    UP000092460    UP000007798    UP000008143    UP000053641    UP000233220    UP000075884    UP000005640    UP000192220    UP000007648    UP000261660    UP000001554    UP000261600    UP000054081    UP000198419    UP000001074    UP000007754    UP000053858    UP000092445    UP000078200    UP000031443    UP000053258    UP000075880    UP000028760   

PRIDE

H9IV80   

Pfam

PF00795   CN_hydrolase        + More
PF02540   NAD_synthase
PF00566   RabGAP-TBC

Interpro

IPR003010   C-N_Hydrolase        + More
IPR014729   Rossmann-like_a/b/a_fold       
IPR036526   C-N_Hydrolase_sf       
IPR014445   Gln-dep_NAD_synthase       
IPR003694   NAD_synthase       
IPR022310   NAD/GMP_synthase       
IPR000195   Rab-GTPase-TBC_dom       
IPR035969   Rab-GTPase_TBC_sf       

SUPFAM

SSF56317   SSF56317        + More
SSF47923   SSF47923       

Gene 3D

3.40.50.620     3.60.110.10    

CDD

cd00553  NAD_synthase

ProteinModelPortal

H9IV80   A0A2H1WA98   A0A2H1VEG0   A0A2A4JVD5   A0A194Q906   A0A3S2M6H4   + More
A0A212EY75   A0A194R9P4   A0A1B6GM02   A0A1B6JE34   D1ZZT1   A0A1B6KSA4   A0A067R837   A0A2J7RRV5   A0A182GI80   A0A034VB33   A0A2J7RRY1   A0A336KV63   A0A0K8W6T7   A0A1J1HV96   U4U8I8   A0A0A1XD61   A0A1W4XJK8   A0A1B6D2S2   A0A1B6D5S3   A0A1Y1KLN7   A0A1Q3G1Q7   A0A2P8ZCY9   T1PKA9   A0A1I8NS65   A0A1Q3G1P3   V9KIP6   Q16E59   Q16Z66   A0A0Q9WMA9   B4M2T6   A0A1S3CXU3   A0A1A8Q9N7   A0A182TC16   B4JL37   A0A0M3QZQ0   A0A1A8A7H0   A0A3B3XLH7   U3I5Q1   A0A1A8L7W3   E0VPD9   U3K2E3   B3MW01   G1MU36   B4L7J5   A0A218URA9   A0A3B0JXK5   F1P4D3   A0A2M4AMM0   A0A091JTW6   A0A1L8GIT4   W4XND2   A0A1A9WFA1   B4Q2E8   A0A2J8S6C0   A0A1W4VGV4   A0A0J7KXT5   B3NWK7   A0A2J8S689   Q29HW0   B4GY71   A0A1A9YF37   A0A1B0C7C8   B4NC89   B1H2T4   A0A099ZVA5   A0A2K6SEN9   A0A182N052   A0A0B4J216   A0A2P4T031   R0L011   A0A2I4AND5   A0A3P4LZZ1   A0A091QST8   A0A087VMG6   G3VZL4   Q5ZMA6   A0A3Q3FHF9   A0A2J8IQ76   C3Y7L9   A0A3Q3JFD8   A0A093NCQ3   A0A226P2X0   G1PXJ9   H0Z4H8   A0A0A0AK77   A0A1B0AHA3   A0A2J8S6A6   A0A1A9VWF6   A0A091VB37   M7B7J6   A0A212DGM2   A0A093QM28   A0A182JFP2   A0A087XA41  

PDB

3ILV     E-value=8.89892e-11,     Score=158

KEGG

101735515    K01950 NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] | (RefSeq) probable glutamine-dependent NA

GO

GO:0009435   GO:0003952   GO:0005524   GO:0016021   GO:0005737   GO:0004359   GO:0016787   GO:0005829  

PANTHER

PTHR23090  

Length:

246

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02072

Exp number, first 60 AAs:

0.02072

Total prob of N-in:

0.00942

outside

1  -  246

 

 

Pi

228.827833

Theta

177.704315

Tajima's D

1.168503

CLR

0

CSRT

0.706564671766412

Interpretation

Uncertain