Gene

KWMTBOMO07943  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001162

Annotation

cytochrome_P450_CYP4G25_[Bombyx_mori]

Location

Bomo_Chr13(-):10620359-10632074      View in EpiBrowser

Full name

Cytochrome P450 4g15      

Alternative Name

CYPIVG15

Location in the cell

Mitochondrial   Reliability : 1.1 Nuclear   Reliability : 1.45

CDS

ATGAGCTATACAAACGCAGAAAATGTAGTGCCTACAAGCACGTTTTCTGCGATCAACCTCTTCTATGTGTTACTTGTGCCGGCCGTAATCCTCTGGTACGCCTACTGGCGAATGTCAAGGCGGCGGTTGTATGAGCTTGCTGACAAACTAAATGGGCCTCCAGGACTTCCGTTACTCGGGAACGCCCTGGAATTCGTCGGTGGATCTGCTGACATCTTCAGAAACATAGTTCAGAAAAGCGCTGACTACGATCACGAATCCGTCGTTAAGATCTGGATAGGACCTCGTCTCCTCGTCTTTCTGTACGATCCTCGCGACGTGGAAGTCATCCTGAGTAGTCACGTTTACATCGATAAAGCTGAGGAATACCGTTTCTTCAAACCATGGCTCGGAAACGGTCTTCTTATCAGTACTGGTCAAAAATGGAGGTCTCATCGTAAACTTATCGCCCCCACATTCCATCTGAACGTTTTGAAGAGTTTCATAGACTTATTCAACGCCAACTCAAGAGCTGTTGTGGACAAACTTAAAAAGGAAGCTAGTAATTTTGATTGCCATGACTACATGAGCGAGTGCACGGTTGAAATTTTACTGGAAACTGCTATGGGTGTGAGCAAGAGTACACAAGATCAAAGCGGATTCGAATATGCTATGGCCGTTATGAAAATGTGCGATATACTTCACTTGAGACACACAAAGATTTGGCTGCGACCGGATTTGTTATTTAAATTTACAGATTACGCTAAAAACCAAACCAAGCTCCTTGATATAATTCATGGCTTGACTAAAAAGGTAATAAAGAGGAAGAAAGAAGAATTCGCATCTGGTAAGAAGCCGTCCAATTTGAATGAAACTGCCACCACAAGCGAGCCGTCTACAGGGAAATTGACTTCAGTGGAAGGACTTTCTTTCGGCCAATCATCCGGTCTCAAGGATGACTTAGACGTTGACGATGATGTCGGACAAAAGAAACGTTTGGCCTTCCTTGATCTGTTGCTGGAGAGTTCACAAAGTGGTGTGGCCATTTCCGATGAGGAAATCAAAGAACAAGTAGACACTATTATGTTTGAGGGTCACGACACAACAGCTGCCGGAAGTAGTTTCTTCCTATCAATGATGGGTATTCATCAAGATATACAAGACAAAGTCATTGAAGAACTGGACCAGATATTTGGTGACTCAGATCGCCCAGTTACGTTCCAAGACACTTTGGAGATGAAGTACTTGGAAAGGTGCCTTATGGAAACTCTGAGATTATACCCGCCAGTGCCGATCATCGCTCGGCAAGTTAATCAAGAAATCACCTTACCATCCAATGGAAAGAAAATCCCAGCCGGAACAACATTGGTGATAGCTACATATAAACTTCATCGCCGCCCTGACGTTTACCCAAATCCAAACAAATTTGACCCTGACAACTTCCTTCCGGAACGTTCCGCCAACAGACATTATTATGCGTTCGTGCCTTTTTCAGCTGGACCAAGAAGTTGCGTTGGACGTAAATACGCAATGCTCAAATTGAAGGTGATCCTTTCTACAATTTTGAGAAATTTCCGAGTAATATCAGATCTTAAAGAATCAGATTTCAAACTGCAAGCGGACATCATTCTGAAACGGGCCGAAGGATTCCAAGTACGCTTACAGCCCCGCAAGAGAATGGCCAAGGCTTAA

Protein

MSYTNAENVVPTSTFSAINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNGPPGLPLLGNALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKDDLDVDDDVGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRMAKA

Description

Probably involved in steroid hormones biosynthesis.

Cofactor

heme

Similarity

Belongs to the cytochrome P450 family.

Keywords

Complete proteome   Endoplasmic reticulum   Heme   Iron   Membrane   Metal-binding   Microsome   Monooxygenase   Oxidoreductase   Reference proteome  

Feature

chain  Cytochrome P450 4g15

Uniprot

H9IV82   L0N6G3   L0N5E6   Q1HPS6   L0N5E1   L0N705   + More
D5L0M7   D2KC48   Q5NT77   X5DT29   A0A3S2LV85   J7FKN5   S4VGS2   A0A0N1IPN2   A0A2I6RJM8   A0A194Q911   I4DIM5   A0A345W863   A0A0C5CGX0   A0A2A4J977   A0A2W1BR68   A0A248QEH7   A0A068EWN8   A0A0K8TV56   D2JLK3   S4NTB2   A0A1V0D9C4   Q5YJK1   A0A212FAI3   A0A0L7KSJ2   A0A1W4X6W1   B0WQV0   A0A1Q3FQS4   Q17DS9   A0A1W6L1L0   A0A182H312   A0A1Q3FR66   Q3I413   A0A182YH39   A0A182LRX0   A0A182RVW8   A0A182N9Y9   A0A182IJ93   A0A2M3Z3M6   A0A084VQ44   A0A158NCC3   A0A182W5Z8   T1E750   A0A310S648   A0A2M3Z3F0   W5JIT2   K7IZ06   A0A195BX50   A0A232F2E7   A0A0K1YWB8   A0A182FMB4   F4WX78   A0A182VA75   F5HL83   A0A182IDW2   A0A195F9G5   A0A0M9A9M0   A0A154P567   V5T6Q9   A0A0C5C1K2   A0A151WFP5   A0A151J5L5   D1ZZJ8   A0A1J1HSQ0   E2BGM0   A0A0L7RDT3   S5CK55   A0A088AIK9   Q306I1   S5CFF1   A0A182PU94   A0A1S3D5P4   A0A3Q0J2U9   A0A1D1XVZ8   A0A3Q0IYF1   E2B1W9   A0A068F827   A0A0L0CJW1   A0A026WV00   A0A1B6D6P6   B4R344   B4IK20   A0A182K968   A0A1Y1KL02   A0A3G2M0D3   B3NUD0   A0A1W4V117   A0A1L8E405   A0A1B1W254   Q8IR88   Q9VYY4   A0A195CEH5   A0A345W866   T1P8M2  

EC Number

1.14.-.-

Pubmed

19121390    19909380    24361403    22984814    25315858    26354079    + More
22651552    28756777    28881445    26017144    19954531    23622113    15716002    22118469    26227816    17510324    26483478    25244985    24438588    21347285    20920257    23761445    20075255    28648823    21719571    12364791    14747013    17210077    24324583    18362917    19820115    20798317    17069637    25880816    26108605    24508170    30249741    17994087    28004739    27444410    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    10891384    12537569   

EMBL

BABH01000675    AK289272    BAM73799.1    AK289275    BAM73802.1    AK289276    + More
BAM73803.1    DQ443326    ABF51415.1    AK289271    BAM73798.1    AK289269    BAM73796.1    GU731532    ADE05582.1    GU205081    ACZ97444.1    AB196795    BAD81026.1    KF701159    AHW57329.1    RSAL01000173    RVE45071.1    JX310087    AFP20598.1    KC789746    AGO62001.1    KQ460202    KPJ17172.1    KY304477    AUN86408.1    KQ459299    KPJ01904.1    AK401143    BAM17765.1    MG829854    AXJ21601.1    KP001142    AJN91187.1    NWSH01002335    PCG68501.1    KZ149944    PZC76821.1    KX443460    ASO98035.1    KM016724    AID54876.1    GCVX01000062    JAI18168.1    GQ915319    ACZ97413.1    GAIX01012261    JAA80299.1    KY212034    ARA91598.1    AY390259    AAR26517.1    AGBW02009477    OWR50723.1    JTDY01006357    KOB66075.1    DS232046    EDS33030.1    GFDL01005140    JAV29905.1    CH477291    EAT44585.1    KX609526    ARN17933.1    JXUM01106399    JXUM01106400    KQ565051    KXJ71408.1    GFDL01005132    JAV29913.1    DQ117464    AAZ94273.1    AXCM01006317    GGFM01002297    MBW23048.1    ATLV01015123    KE525003    KFB40088.1    ADTU01011802    GAMD01003352    JAA98238.1    KQ768821    OAD53067.1    GGFM01002300    MBW23051.1    ADMH02001125    ETN64031.1    KQ976396    KYM92870.1    NNAY01001171    OXU24891.1    KP859400    AKZ17710.1    GL888417    EGI61202.1    AAAB01008885    EAL40625.3    EGK97044.1    EGK97045.1    APCN01008038    APCN01008039    KQ981727    KYN37083.1    KQ435720    KOX78679.1    KQ434820    KZC06992.1    KF656702    AHB59619.1    KP001141    AJN91186.1    KQ983211    KYQ46660.1    KQ979973    KYN18382.1    KQ971338    EFA02880.1    CVRI01000019    CRK90412.1    GL448193    EFN85148.1    KQ414614    KOC68891.1    KC243983    AGQ03779.1    DQ244075    ABB36785.1    KC243984    AGQ03780.1    GDJX01021362    JAT46574.1    GL444981    EFN60325.1    KJ702273    AID61427.1    JRES01000290    KNC32693.1    KK107087    QOIP01000001    EZA59842.1    RLU27419.1    GEDC01015940    JAS21358.1    CM000366    EDX17646.1    CH480851    EDW51392.1    GEZM01080918    JAV61994.1    MG840833    AYN79709.1    CH954180    EDV46045.1    GFDF01000604    JAV13480.1    KU833274    ANW46746.1    AE014298    AAN09635.2    AF159624    AY060719    KQ977873    KYM99110.1    MG829857    AXJ21604.1    KA645002    AFP59631.1   

Proteomes

UP000005204    UP000283053    UP000053240    UP000053268    UP000218220    UP000007151    + More
UP000037510    UP000192223    UP000002320    UP000008820    UP000069940    UP000249989    UP000076408    UP000075883    UP000075900    UP000075884    UP000075880    UP000030765    UP000005205    UP000075920    UP000000673    UP000002358    UP000078540    UP000215335    UP000069272    UP000007755    UP000075903    UP000007062    UP000075840    UP000078541    UP000053105    UP000076502    UP000075809    UP000078492    UP000007266    UP000183832    UP000008237    UP000053825    UP000005203    UP000075885    UP000079169    UP000000311    UP000037069    UP000053097    UP000279307    UP000000304    UP000001292    UP000075881    UP000008711    UP000192221    UP000000803    UP000078542   

PRIDE

H9IV82    L0N6G3    L0N5E6    Q1HPS6    L0N5E1    L0N705    + More
Q306I1    Q8IR88    Q9VYY4   

Pfam

PF00067   p450

Interpro

IPR036396   Cyt_P450_sf        + More
IPR002401   Cyt_P450_E_grp-I       
IPR017972   Cyt_P450_CS       
IPR001128   Cyt_P450       

SUPFAM

SSF48264   SSF48264       

Gene 3D

1.10.630.10    

ProteinModelPortal

H9IV82   L0N6G3   L0N5E6   Q1HPS6   L0N5E1   L0N705   + More
D5L0M7   D2KC48   Q5NT77   X5DT29   A0A3S2LV85   J7FKN5   S4VGS2   A0A0N1IPN2   A0A2I6RJM8   A0A194Q911   I4DIM5   A0A345W863   A0A0C5CGX0   A0A2A4J977   A0A2W1BR68   A0A248QEH7   A0A068EWN8   A0A0K8TV56   D2JLK3   S4NTB2   A0A1V0D9C4   Q5YJK1   A0A212FAI3   A0A0L7KSJ2   A0A1W4X6W1   B0WQV0   A0A1Q3FQS4   Q17DS9   A0A1W6L1L0   A0A182H312   A0A1Q3FR66   Q3I413   A0A182YH39   A0A182LRX0   A0A182RVW8   A0A182N9Y9   A0A182IJ93   A0A2M3Z3M6   A0A084VQ44   A0A158NCC3   A0A182W5Z8   T1E750   A0A310S648   A0A2M3Z3F0   W5JIT2   K7IZ06   A0A195BX50   A0A232F2E7   A0A0K1YWB8   A0A182FMB4   F4WX78   A0A182VA75   F5HL83   A0A182IDW2   A0A195F9G5   A0A0M9A9M0   A0A154P567   V5T6Q9   A0A0C5C1K2   A0A151WFP5   A0A151J5L5   D1ZZJ8   A0A1J1HSQ0   E2BGM0   A0A0L7RDT3   S5CK55   A0A088AIK9   Q306I1   S5CFF1   A0A182PU94   A0A1S3D5P4   A0A3Q0J2U9   A0A1D1XVZ8   A0A3Q0IYF1   E2B1W9   A0A068F827   A0A0L0CJW1   A0A026WV00   A0A1B6D6P6   B4R344   B4IK20   A0A182K968   A0A1Y1KL02   A0A3G2M0D3   B3NUD0   A0A1W4V117   A0A1L8E405   A0A1B1W254   Q8IR88   Q9VYY4   A0A195CEH5   A0A345W866   T1P8M2  

PDB

6C94     E-value=6.60054e-67,     Score=646

KEGG

100127117    K15001 cytochrome P450 family 4 [EC:1.14.-.-] | (RefSeq) Cyp4g25, CYP4G22, CYP4G23; cytochrome P450

GO

GO:0020037   GO:0016021   GO:0005506   GO:0016705   GO:0004497   GO:0046872   GO:0005789   GO:0016020   GO:0043015   GO:0007169   GO:0006412   GO:0016876   GO:0043039   GO:0055114  

Subcellular location

Endoplasmic reticulum membrane  
Microsome membrane  

Length:

556

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.33054

Exp number, first 60 AAs:

22.10303

Total prob of N-in:

0.82018

POSSIBLE N-term signal

sequence

inside

1  -  12

TMhelix

13  -  35

outside

36  -  556

 

 

Pi

219.221552

Theta

167.849512

Tajima's D

-1.177886

CLR

0.356203

CSRT

0.109844507774611

Interpretation

Uncertain