Gene

KWMTBOMO07926

Annotation

glycosyltransferase_precursor_[Bombyx_mori]

Location

Bomo_Chr13(-):10237542-10239576      View in EpiBrowser

Full name

Beta-1,4-mannosyltransferase egh      

Alternative Name

Protein egghead
Protein zeste-white 4

Location in the cell

PlasmaMembrane   Reliability : 4.684

CDS

ATGATCAGAGGGCGAATAAAACATTTGCTACATTGCATGTTTTTTTTACTCTTCATTTTTTTTTTCCTCGTGTTTGCTGGGGCTATTAATCTGGATGATAAAGAAAAAGAATTCATTGATCCTTGGGAGAATTATGGAGTTTTTGGTGCACTTATATTGTATATCCTGCGACTTCTGACTTTACTCACAATACCACAGGTGCTCTGCAATTTTGCTGGCCTAACTTTATTCAACGCTTTTCCTGGAAAAATTCGACTGAAAAGCTCACCATTACTTGCTCCGTTTATTTGCATAAGAGTGGTCACAAGAGGGGATTTCCCAAAACTGGTAAAAGATAATGTGAATAGGAACATGAATAAGTGTATAGATGTTGGCATGGAGAACTTTATGATAGAAGTTGTGACTGACAAAGCTATAAATTTGCCAAAACACCGAAAAGTAAGAGAAGTAGTAGTTCCATCAGATTATCAGACTAAATCTGGAGCTTTATTCAAGGCGCGAGCCCTACAATATTGTTTAGAAGATCAAGTGAACATACTGACAGAGACTGATTGGATTGTACATTTAGATGAAGAGACTCTTTTGACAGAAAATTCATTAAGGGGAATTTTAAATTTTGTTATGGATGGACAGTATCAATTTGGCCAGGGTCTCATCACTTATGCCAATGAACAGATTGTAAATTGGTTGACAACATTAGCAGATAGTTTCAGAGTTGCTGATGATATGGGCAAGCTAAGGCTGCAATTTTATCTATTCCATAAACCACTGTTTAGTTGGAAAGGATCTTATGTAGTAACACAAGTAAGTGCAGAGAAGAAAGTATCTTTTGATAATGGCCTTGATGGGTCAGTGGCTGAAGATTGTTTTTTTGCCATGAAGGCATATAAGGAAGGCTACACATTTAATTTTGTTGAAGGAGAAATGTGGGAAAAATCCCCTTTTACTCTTTGGGATTTCATGCAGCAACGAAAAAGATGGATTCAAGACATTGCTTGTGGATTTACAGCAGCTGTTAACATTTATATGTACATTTTTGGAGTCATCAAGTCATTTCCTGTACACAGATTTGGACCATTAAAGTTTATACTATTTGTTGGGGGAGCTTTGGCTACTATTCCATTAAACATAGTTATTGAAAATATTGCAGTTATTTGGGGAATGTTAGGAAAAAAGCACAAATTTTATATTGTTAACAAAGAAATTAAAACACCTGTTACTGTGTGA

Protein

MIRGRIKHLLHCMFFLLFIFFFLVFAGAINLDDKEKEFIDPWENYGVFGALILYILRLLTLLTIPQVLCNFAGLTLFNAFPGKIRLKSSPLLAPFICIRVVTRGDFPKLVKDNVNRNMNKCIDVGMENFMIEVVTDKAINLPKHRKVREVVVPSDYQTKSGALFKARALQYCLEDQVNILTETDWIVHLDEETLLTENSLRGILNFVMDGQYQFGQGLITYANEQIVNWLTTLADSFRVADDMGKLRLQFYLFHKPLFSWKGSYVVTQVSAEKKVSFDNGLDGSVAEDCFFAMKAYKEGYTFNFVEGEMWEKSPFTLWDFMQQRKRWIQDIACGFTAAVNIYMYIFGVIKSFPVHRFGPLKFILFVGGALATIPLNIVIENIAVIWGMLGKKHKFYIVNKEIKTPVTV

Description

Glycosyltransferase with a proposed role in glycosphingolipid biosynthesis. Neurogenic protein implicated in epithelial development. Critical component of a differential oocyte-follicle cell adhesive system.

Similarity

Belongs to the glycosyltransferase 2 family.

Keywords

Complete proteome   Developmental protein   Glycosyltransferase   Membrane   Reference proteome   Transferase   Transmembrane   Transmembrane helix  

Feature

chain  Beta-1,4-mannosyltransferase egh

Uniprot

G1UHW4   A0A2W1BPD5   A0A0L7LQN8   A0A2H1V8V0   A0A3S2LVU1   A0A142I0M6   + More
A0A2A4JX61   D9ID39   D3JVQ8   A0A212EPC8   A0A067R6G9   V5I8X6   E1ZZ85   A0A1B6HJR4   A0A0C9PL91   A0A1B6KNQ7   B3P931   D2A043   A0A2P6KP78   T1JBR4   A4V3W0   O01346   B4I9W7   A0A151XJ08   A0A2J7PFZ4   A0A2L2XZW9   A0A195CR99   B4MSR7   B4Q0Z1   A0A1I8PNZ8   C0PTV2   A0A195BVY6   E2BLQ5   A0A158NEH7   A0A3L8E1J9   F4WVG4   A0A026WMR3   A0A0M4EIY8   A0A1A9WA57   A0A195EMY3   A0A1W4V8N3   A0A232EUZ7   W8AYB0   A0A195FLC8   B4M782   B4L1D8   A0A0A9Z343   A0A3Q0J491   A0A1W4X1W1   A0A1Q3FDJ7   B3MYW8   K7IYU6   A0A0K8SCJ5   B4JX91   A0A0A1WW35   Q29GT6   A0A084VH05   A0A3B0J6R3   A0A1I8MPQ9   B4GUX8   A0A182N1I5   A0A182QLH8   A0A034VEM3   T1E219   A0A2S2QLW5   A0A182IWH4   J9JTY1   A0A2A3EHX8   A0A023ESK1   A0A0K8V3A1   A0A182XYA8   A0A1B0D345   A0A1B0GKC5   A0A182R259   U5EWT3   Q0IFM0   A0A182T4G0   A0A336LPY6   A0A2M3ZKU7   A0A182VVF5   A0A182PWH3   A0A1Q3FDL8   T1I475   A0A2M4BNA4   E0W2B3   A0A182KER3   A0A293MXZ8   A0A182FJZ2   W5JJS7   A0A224XPE3   A0A182VBP5   A0A182U5T9   Q7Q4U5   A0A2R5LHX5   A0A2R7VWS6   A0A1D2MW90   A0A1L8E1D5   A0A2M4AN73   A0A1L8E183   A0A182MRW6  

EC Number

2.4.1.-

Pubmed

22635270    28756777    26227816    22118469    24845553    20798317    + More
17994087    18362917    19820115    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    9012507    10731137    12454022    26561354    17550304    21347285    30249741    21719571    24508170    28648823    24495485    18057021    25401762    26823975    20075255    25830018    15632085    23185243    24438588    25315136    25348373    24330624    24945155    26483478    25244985    17510324    20566863    20920257    23761445    12364791    14747013    17210077    27289101   

EMBL

AB620071    BAK82123.1    KZ149944    PZC76838.1    JTDY01000299    KOB77813.1    + More
ODYU01001272    SOQ37258.1    RSAL01000173    RVE45088.1    KR362876    AMR34865.1    NWSH01000456    PCG76288.1    HM135157    ADJ10634.1    GU321343    ADB79796.1    AGBW02013511    OWR43317.1    KK852918    KDR13845.1    GALX01003920    JAB64546.1    GL435311    EFN73500.1    GECU01032782    GECU01019442    JAS74924.1    JAS88264.1    GBYB01001773    GBYB01013103    JAG71540.1    JAG82870.1    GEBQ01026888    JAT13089.1    CH954183    EDV45636.1    KQ971338    EFA02466.1    MWRG01007646    PRD28137.1    JH432018    AE014298    BT133075    AAN09081.1    AEX93160.1    AHN59300.1    U15602    U21218    AF233288    AL138972    CH480825    EDW43998.1    KQ982080    KYQ60369.1    NEVH01025635    PNF15253.1    IAAA01007723    IAAA01007724    IAAA01007725    IAAA01007726    LAA01428.1    KQ977444    KYN02634.1    CH963851    EDW75156.1    CM000162    EDX01358.1    KRK06079.1    BT071797    ACN43733.1    KQ976401    KYM92445.1    GL449036    EFN83389.1    ADTU01013344    QOIP01000001    RLU26402.1    GL888387    EGI61785.1    KK107154    EZA56946.1    CP012528    ALC48978.1    KQ978625    KYN29640.1    NNAY01002072    OXU22163.1    GAMC01015458    JAB91097.1    KQ981490    KYN41146.1    CH940653    EDW62649.1    KRF80747.1    KRF80748.1    KRF80749.1    KRF80750.1    KRF80751.1    CH933810    EDW06659.1    GBHO01007379    GDHC01017011    JAG36225.1    JAQ01618.1    GFDL01009409    JAV25636.1    CH902632    EDV32812.1    KPU74152.1    GBRD01014818    JAG51008.1    CH916376    EDV95367.1    GBXI01014481    GBXI01011496    GBXI01004846    GBXI01002236    JAC99810.1    JAD02796.1    JAD09446.1    JAD12056.1    CH379064    EAL32023.1    KRT06776.1    KRT06777.1    ATLV01013120    KE524840    KFB37249.1    OUUW01000003    SPP77874.1    CH479192    EDW26515.1    AXCN02001382    AXCN02001383    AXCN02001384    GAKP01017985    GAKP01017984    GAKP01017983    JAC40969.1    GALA01001144    JAA93708.1    GGMS01009478    MBY78681.1    ABLF02039332    KZ288254    PBC30872.1    JXUM01083347    GAPW01001361    KQ563371    JAC12237.1    KXJ73959.1    GDHF01028883    GDHF01018930    JAI23431.1    JAI33384.1    AJVK01010863    AJVK01010864    AJWK01028657    AJWK01028658    AJWK01028659    AJWK01028660    GANO01001266    JAB58605.1    CH477312    EAT43883.1    UFQT01000099    SSX19885.1    GGFM01008371    MBW29122.1    GFDL01009375    JAV25670.1    ACPB03015936    ACPB03015937    ACPB03015938    ACPB03015939    GGFJ01005117    MBW54258.1    DS235875    EEB19769.1    GFWV01020271    MAA44999.1    ADMH02000938    ETN64627.1    GFTR01006393    JAW10033.1    AAAB01008963    EAA12038.3    GGLE01004963    MBY09089.1    KK854118    PTY11598.1    LJIJ01000455    ODM97323.1    GFDF01001628    JAV12456.1    GGFK01008909    MBW42230.1    GFDF01001627    JAV12457.1    AXCM01006665   

Proteomes

UP000037510    UP000283053    UP000218220    UP000007151    UP000027135    UP000000311    + More
UP000008711    UP000007266    UP000000803    UP000001292    UP000075809    UP000235965    UP000078542    UP000007798    UP000002282    UP000095300    UP000078540    UP000008237    UP000005205    UP000279307    UP000007755    UP000053097    UP000092553    UP000091820    UP000078492    UP000192221    UP000215335    UP000078541    UP000008792    UP000009192    UP000079169    UP000192223    UP000007801    UP000002358    UP000001070    UP000001819    UP000030765    UP000268350    UP000095301    UP000008744    UP000075884    UP000075886    UP000075880    UP000007819    UP000242457    UP000069940    UP000249989    UP000076408    UP000092462    UP000092461    UP000075900    UP000008820    UP000075901    UP000075920    UP000075885    UP000015103    UP000009046    UP000075881    UP000069272    UP000000673    UP000075903    UP000075902    UP000007062    UP000094527    UP000075883   

PRIDE

G1UHW4    O01346    C0PTV2   

Pfam

PF13632   Glyco_trans_2_3

Interpro

IPR029044   Nucleotide-diphossugar_trans        + More
IPR001173   Glyco_trans_2-like       
IPR027389   B_mannosylTrfase_Bre-3/Egh       

SUPFAM

SSF53448   SSF53448       

Gene 3D

3.90.550.10    

ProteinModelPortal

G1UHW4   A0A2W1BPD5   A0A0L7LQN8   A0A2H1V8V0   A0A3S2LVU1   A0A142I0M6   + More
A0A2A4JX61   D9ID39   D3JVQ8   A0A212EPC8   A0A067R6G9   V5I8X6   E1ZZ85   A0A1B6HJR4   A0A0C9PL91   A0A1B6KNQ7   B3P931   D2A043   A0A2P6KP78   T1JBR4   A4V3W0   O01346   B4I9W7   A0A151XJ08   A0A2J7PFZ4   A0A2L2XZW9   A0A195CR99   B4MSR7   B4Q0Z1   A0A1I8PNZ8   C0PTV2   A0A195BVY6   E2BLQ5   A0A158NEH7   A0A3L8E1J9   F4WVG4   A0A026WMR3   A0A0M4EIY8   A0A1A9WA57   A0A195EMY3   A0A1W4V8N3   A0A232EUZ7   W8AYB0   A0A195FLC8   B4M782   B4L1D8   A0A0A9Z343   A0A3Q0J491   A0A1W4X1W1   A0A1Q3FDJ7   B3MYW8   K7IYU6   A0A0K8SCJ5   B4JX91   A0A0A1WW35   Q29GT6   A0A084VH05   A0A3B0J6R3   A0A1I8MPQ9   B4GUX8   A0A182N1I5   A0A182QLH8   A0A034VEM3   T1E219   A0A2S2QLW5   A0A182IWH4   J9JTY1   A0A2A3EHX8   A0A023ESK1   A0A0K8V3A1   A0A182XYA8   A0A1B0D345   A0A1B0GKC5   A0A182R259   U5EWT3   Q0IFM0   A0A182T4G0   A0A336LPY6   A0A2M3ZKU7   A0A182VVF5   A0A182PWH3   A0A1Q3FDL8   T1I475   A0A2M4BNA4   E0W2B3   A0A182KER3   A0A293MXZ8   A0A182FJZ2   W5JJS7   A0A224XPE3   A0A182VBP5   A0A182U5T9   Q7Q4U5   A0A2R5LHX5   A0A2R7VWS6   A0A1D2MW90   A0A1L8E1D5   A0A2M4AN73   A0A1L8E183   A0A182MRW6  

KEGG

100862829    K02359 egghead protein (zeste-white 4 protein) | (RefSeq) _Bre3, Bm_Bre3; glycosyltransferase

PATHWAY

04320    Dorso-ventral axis formation - Bombyx mori (domestic silkworm)

GO

GO:0019187   GO:0016021   GO:0045165   GO:0007411   GO:0008049   GO:0007299   GO:0042248   GO:0033227   GO:0016325   GO:0007298   GO:0048935   GO:0045434   GO:0046662   GO:0030720   GO:0001744   GO:0006688   GO:0005737   GO:0016333   GO:0030707   GO:0007293   GO:0007281   GO:0016757  

PANTHER

PTHR16779  

Subcellular location

Membrane  

Length:

408

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

89.6222200000001

Exp number, first 60 AAs:

34.30243

Total prob of N-in:

0.99884

POSSIBLE N-term signal

sequence

inside

1  -  8

TMhelix

9  -  31

outside

32  -  45

TMhelix

46  -  68

inside

69  -  330

TMhelix

331  -  348

outside

349  -  362

TMhelix

363  -  385

inside

386  -  408

 

 

Pi

227.464399

Theta

197.756918

Tajima's D

0.562715

CLR

0

CSRT

0.532623368831558

Interpretation

Uncertain