Gene
KWMTBOMO07908
Pre Gene Modal
BGIBMGA001176
Annotation
PREDICTED:_2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline_decarboxylase-like_[Papilio_machaon]
Full name
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Alternative Name
Parahox neighbor
Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
Location in the cell
Nuclear Reliability : 1.731
Sequence
CDS
ATGTCGTTTTTACTTACATATACAATGTCGTTTTTACTTAACATCTCACAAGTAAATGCTCTTAGTGACGAACGTTTTGAGTATGTGTTTAGAAACGTAATTGAATTATATCCCGCAGCTGCGATAGAAGTAGGGAAGAAACGACCATTTAATAATTCAACAGAATTATGTGCTGCTTTTGATAATTATTTGGAAGAGCTGAGTACGGCAGAAAAGAACAAGGTATTCAAATTTCATCCAGATTTAGCCGGAAAGATTTCACAAATGGGAGAGTTAACGCCAGAATCTACAAAAGAGCAGAATTCTGCTGGTTTAAATCAATTGAATTCAGAACAGAAAAGTTTGATAAACCATTATAATGAAAGTTACAAAGAAAAATTTGGATTTCCATTCATTGTATGTGCAAGGGAGAATAAAGTAGCATCAATATTAGAAGGCCTGCAAATCCGATTGAAAAACTCGTCTTTCCAGGAATATCAAACTGCATTAAATGAAGTGAAAAAGATATGCAGATATAGAATCTATGACATTGTTGACGAGAATTAA
Protein
MSFLLTYTMSFLLNISQVNALSDERFEYVFRNVIELYPAAAIEVGKKRPFNNSTELCAAFDNYLEELSTAEKNKVFKFHPDLAGKISQMGELTPESTKEQNSAGLNQLNSEQKSLINHYNESYKEKFGFPFIVCARENKVASILEGLQIRLKNSSFQEYQTALNEVKKICRYRIYDIVDEN
Summary
Description
Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.
Catalytic Activity
5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) = (S)-allantoin + CO2
Subunit
Homodimer.
Similarity
Belongs to the OHCU decarboxylase family.
Belongs to the class-I aminoacyl-tRNA synthetase family.
Belongs to the class-I aminoacyl-tRNA synthetase family.
Keywords
Decarboxylase
Lyase
Peroxisome
Purine metabolism
3D-structure
Complete proteome
Reference proteome
Feature
chain 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Uniprot
H9IV96
A0A2A4J319
A0A2W1BVZ6
A0A0N1I996
A0A212F4I8
A0A232FFF3
+ More
K7J0V7 A0A2P8ZCT1 A0A0L7KQ70 A0A2H1WQ75 K1PA03 A0A2H1WDQ3 A0A3R5WDW9 T1EB70 A0A1Q3FQJ2 C3YZC5 B0WCJ1 A0A2M4AFM4 A0A2M4CUY6 A0A182Q522 A0A1Y1NGH6 A0A1D2MZ07 A0A2M4CV15 Q16ER5 A0A2M4C1G0 A0A0C9R4W1 A0A0P4XF24 A0A182PKU9 A0A0C9RRY6 A0A2M3ZII1 A0A182VTW3 U5EXQ5 A0A0P5GS61 Q1J3A0 A0A182UMZ0 A0A182WZE2 A0A182ICS5 A0A336KHC1 B0WCJ2 A0A3S2NV28 A0A0P6C9F4 A0A182NAY1 A0A182L661 A7UV21 A0A0P6IR48 A0A0U2U2L5 A0A1Y1NFW0 A0A3P9A277 A0A1S3H7Y6 Q0ZDF7 A0A226EKE3 A0A2I4AQE4 E9GJ14 A7RYJ8 A0A326UA10 A0A0P5GAN0 A0A3Q1JKW6 A0A2W4L844 A0A3B4UPQ5 A0A3Q2PQ69 A0A3B4WLZ5 I3K9H9 A0A3Q3A601 A0A3Q4I2C5 F6TMG0 A0A336KLU8 W4XAC4 A0A3G8YJ63 A0A3Q3VP45 A0A2V9KNH4 A0A3Q2VX22 A0A1U7NUJ4 A0A3Q0T2Y0 A0A016QSQ7 A1L259 A0A3Q1CRA1 A0A3P8TT57 A0A3B3YTX9 W5M9S0 A7SCA1 A0A3P9Q469 M3XI16 M9Z162 A0A2I9CW92 A0A1S3NHQ1 Q4S568 A0A3P8WH42 A0A3B3VDI0 Q17JD3 A0A3P8WH61 E6ZIS3 A0A0P7WNR6 H3D593 A0A087XP72 A0A3B3HKS0 A0A3P9MAV8 A0A0A7KGT6 A0A2N5KC24 C3XUZ7 A0A147ALM4
K7J0V7 A0A2P8ZCT1 A0A0L7KQ70 A0A2H1WQ75 K1PA03 A0A2H1WDQ3 A0A3R5WDW9 T1EB70 A0A1Q3FQJ2 C3YZC5 B0WCJ1 A0A2M4AFM4 A0A2M4CUY6 A0A182Q522 A0A1Y1NGH6 A0A1D2MZ07 A0A2M4CV15 Q16ER5 A0A2M4C1G0 A0A0C9R4W1 A0A0P4XF24 A0A182PKU9 A0A0C9RRY6 A0A2M3ZII1 A0A182VTW3 U5EXQ5 A0A0P5GS61 Q1J3A0 A0A182UMZ0 A0A182WZE2 A0A182ICS5 A0A336KHC1 B0WCJ2 A0A3S2NV28 A0A0P6C9F4 A0A182NAY1 A0A182L661 A7UV21 A0A0P6IR48 A0A0U2U2L5 A0A1Y1NFW0 A0A3P9A277 A0A1S3H7Y6 Q0ZDF7 A0A226EKE3 A0A2I4AQE4 E9GJ14 A7RYJ8 A0A326UA10 A0A0P5GAN0 A0A3Q1JKW6 A0A2W4L844 A0A3B4UPQ5 A0A3Q2PQ69 A0A3B4WLZ5 I3K9H9 A0A3Q3A601 A0A3Q4I2C5 F6TMG0 A0A336KLU8 W4XAC4 A0A3G8YJ63 A0A3Q3VP45 A0A2V9KNH4 A0A3Q2VX22 A0A1U7NUJ4 A0A3Q0T2Y0 A0A016QSQ7 A1L259 A0A3Q1CRA1 A0A3P8TT57 A0A3B3YTX9 W5M9S0 A7SCA1 A0A3P9Q469 M3XI16 M9Z162 A0A2I9CW92 A0A1S3NHQ1 Q4S568 A0A3P8WH42 A0A3B3VDI0 Q17JD3 A0A3P8WH61 E6ZIS3 A0A0P7WNR6 H3D593 A0A087XP72 A0A3B3HKS0 A0A3P9MAV8 A0A0A7KGT6 A0A2N5KC24 C3XUZ7 A0A147ALM4
EC Number
4.1.1.97
Pubmed
EMBL
BABH01000740
BABH01000741
NWSH01003540
PCG66136.1
KZ149944
PZC76826.1
+ More
KQ460202 KPJ17200.1 AGBW02010357 OWR48646.1 NNAY01000332 OXU29159.1 PYGN01000101 PSN54301.1 JTDY01007137 KOB65437.1 ODYU01010206 SOQ55167.1 JH823254 EKC18283.1 ODYU01007861 SOQ51002.1 KV595297 OPL21090.1 GAMD01000213 JAB01378.1 GFDL01005279 JAV29766.1 GG666566 EEN54196.1 DS231888 EDS43562.1 GGFK01006259 MBW39580.1 GGFL01004984 MBW69162.1 AXCN02000652 GEZM01003647 JAV96658.1 LJIJ01000367 ODM98283.1 GGFL01004985 MBW69163.1 CH478606 CH478348 EAT32724.1 EAT33180.1 GGFJ01009998 MBW59139.1 GBYB01011334 JAG81101.1 GDIP01242040 GDIQ01245115 JAI81361.1 JAK06610.1 GBYB01008334 GBYB01011335 JAG78101.1 JAG81102.1 GGFM01007605 MBW28356.1 GANO01002429 JAB57442.1 GDIQ01243861 JAK07864.1 CP000358 ABF44034.1 APCN01005756 UFQS01000150 UFQT01000150 SSX00530.1 SSX20910.1 EDS43563.1 RSAL01000063 RVE49513.1 GDIP01018980 JAM84735.1 AAAB01008980 EDO63411.1 GDIQ01018449 JAN76288.1 KT954990 ALR88636.1 GEZM01003646 JAV96659.1 DQ504303 LNIX01000003 OXA57668.1 GL732547 EFX80364.1 DS469553 EDO43473.1 QKUF01000009 PZW29324.1 GDIQ01243862 JAK07863.1 QGUF01001532 PZN18406.1 AERX01010027 UFQS01000659 UFQT01000659 SSX05874.1 SSX26233.1 AAGJ04020514 CP034185 AZI44790.1 QHZH01000051 PYV19167.1 MSTI01000137 OLV16592.1 JHAC01000011 EYB69140.1 EF197726 BC129362 AHAT01003161 DS469622 EDO38622.1 AFYH01043715 AFYH01043716 AFYH01043717 AFYH01043718 AFYH01043719 KC914567 HF678435 AGK27899.1 CCT61358.1 BFAG01000008 GBF06254.1 CAAE01014737 CAG04214.1 CH477233 EAT46770.1 FQ310508 CBN81957.1 JARO02008370 KPP62806.1 AYCK01005755 CP010028 AIZ44419.1 PJQI01000121 PLS81257.1 GG666468 EEN67923.1 GCES01006809 JAR79514.1
KQ460202 KPJ17200.1 AGBW02010357 OWR48646.1 NNAY01000332 OXU29159.1 PYGN01000101 PSN54301.1 JTDY01007137 KOB65437.1 ODYU01010206 SOQ55167.1 JH823254 EKC18283.1 ODYU01007861 SOQ51002.1 KV595297 OPL21090.1 GAMD01000213 JAB01378.1 GFDL01005279 JAV29766.1 GG666566 EEN54196.1 DS231888 EDS43562.1 GGFK01006259 MBW39580.1 GGFL01004984 MBW69162.1 AXCN02000652 GEZM01003647 JAV96658.1 LJIJ01000367 ODM98283.1 GGFL01004985 MBW69163.1 CH478606 CH478348 EAT32724.1 EAT33180.1 GGFJ01009998 MBW59139.1 GBYB01011334 JAG81101.1 GDIP01242040 GDIQ01245115 JAI81361.1 JAK06610.1 GBYB01008334 GBYB01011335 JAG78101.1 JAG81102.1 GGFM01007605 MBW28356.1 GANO01002429 JAB57442.1 GDIQ01243861 JAK07864.1 CP000358 ABF44034.1 APCN01005756 UFQS01000150 UFQT01000150 SSX00530.1 SSX20910.1 EDS43563.1 RSAL01000063 RVE49513.1 GDIP01018980 JAM84735.1 AAAB01008980 EDO63411.1 GDIQ01018449 JAN76288.1 KT954990 ALR88636.1 GEZM01003646 JAV96659.1 DQ504303 LNIX01000003 OXA57668.1 GL732547 EFX80364.1 DS469553 EDO43473.1 QKUF01000009 PZW29324.1 GDIQ01243862 JAK07863.1 QGUF01001532 PZN18406.1 AERX01010027 UFQS01000659 UFQT01000659 SSX05874.1 SSX26233.1 AAGJ04020514 CP034185 AZI44790.1 QHZH01000051 PYV19167.1 MSTI01000137 OLV16592.1 JHAC01000011 EYB69140.1 EF197726 BC129362 AHAT01003161 DS469622 EDO38622.1 AFYH01043715 AFYH01043716 AFYH01043717 AFYH01043718 AFYH01043719 KC914567 HF678435 AGK27899.1 CCT61358.1 BFAG01000008 GBF06254.1 CAAE01014737 CAG04214.1 CH477233 EAT46770.1 FQ310508 CBN81957.1 JARO02008370 KPP62806.1 AYCK01005755 CP010028 AIZ44419.1 PJQI01000121 PLS81257.1 GG666468 EEN67923.1 GCES01006809 JAR79514.1
Proteomes
UP000005204
UP000218220
UP000053240
UP000007151
UP000215335
UP000002358
+ More
UP000245037 UP000037510 UP000005408 UP000001554 UP000002320 UP000075886 UP000094527 UP000008820 UP000075885 UP000075920 UP000002431 UP000075903 UP000076407 UP000075840 UP000283053 UP000075884 UP000075882 UP000007062 UP000265140 UP000085678 UP000198287 UP000192220 UP000000305 UP000001593 UP000248806 UP000265040 UP000261420 UP000265000 UP000261360 UP000005207 UP000264800 UP000261580 UP000002280 UP000007110 UP000276417 UP000261620 UP000264840 UP000186607 UP000261340 UP000020492 UP000000437 UP000257160 UP000265080 UP000261480 UP000018468 UP000242638 UP000008672 UP000236569 UP000087266 UP000265120 UP000261500 UP000034805 UP000007303 UP000028760 UP000001038 UP000265180 UP000030634 UP000235033
UP000245037 UP000037510 UP000005408 UP000001554 UP000002320 UP000075886 UP000094527 UP000008820 UP000075885 UP000075920 UP000002431 UP000075903 UP000076407 UP000075840 UP000283053 UP000075884 UP000075882 UP000007062 UP000265140 UP000085678 UP000198287 UP000192220 UP000000305 UP000001593 UP000248806 UP000265040 UP000261420 UP000265000 UP000261360 UP000005207 UP000264800 UP000261580 UP000002280 UP000007110 UP000276417 UP000261620 UP000264840 UP000186607 UP000261340 UP000020492 UP000000437 UP000257160 UP000265080 UP000261480 UP000018468 UP000242638 UP000008672 UP000236569 UP000087266 UP000265120 UP000261500 UP000034805 UP000007303 UP000028760 UP000001038 UP000265180 UP000030634 UP000235033
PRIDE
Interpro
IPR018020
OHCU_decarboxylase
+ More
IPR036778 OHCU_decarboxylase_sf
IPR017580 OHCU_decarboxylase-1
IPR010736 SHIPPO-rpt
IPR002302 Leu-tRNA-ligase
IPR013155 M/V/L/I-tRNA-synth_anticd-bd
IPR009080 tRNAsynth_Ia_anticodon-bd
IPR002300 aa-tRNA-synth_Ia
IPR014729 Rossmann-like_a/b/a_fold
IPR001412 aa-tRNA-synth_I_CS
IPR009008 Val/Leu/Ile-tRNA-synth_edit
IPR036778 OHCU_decarboxylase_sf
IPR017580 OHCU_decarboxylase-1
IPR010736 SHIPPO-rpt
IPR002302 Leu-tRNA-ligase
IPR013155 M/V/L/I-tRNA-synth_anticd-bd
IPR009080 tRNAsynth_Ia_anticodon-bd
IPR002300 aa-tRNA-synth_Ia
IPR014729 Rossmann-like_a/b/a_fold
IPR001412 aa-tRNA-synth_I_CS
IPR009008 Val/Leu/Ile-tRNA-synth_edit
Gene 3D
ProteinModelPortal
H9IV96
A0A2A4J319
A0A2W1BVZ6
A0A0N1I996
A0A212F4I8
A0A232FFF3
+ More
K7J0V7 A0A2P8ZCT1 A0A0L7KQ70 A0A2H1WQ75 K1PA03 A0A2H1WDQ3 A0A3R5WDW9 T1EB70 A0A1Q3FQJ2 C3YZC5 B0WCJ1 A0A2M4AFM4 A0A2M4CUY6 A0A182Q522 A0A1Y1NGH6 A0A1D2MZ07 A0A2M4CV15 Q16ER5 A0A2M4C1G0 A0A0C9R4W1 A0A0P4XF24 A0A182PKU9 A0A0C9RRY6 A0A2M3ZII1 A0A182VTW3 U5EXQ5 A0A0P5GS61 Q1J3A0 A0A182UMZ0 A0A182WZE2 A0A182ICS5 A0A336KHC1 B0WCJ2 A0A3S2NV28 A0A0P6C9F4 A0A182NAY1 A0A182L661 A7UV21 A0A0P6IR48 A0A0U2U2L5 A0A1Y1NFW0 A0A3P9A277 A0A1S3H7Y6 Q0ZDF7 A0A226EKE3 A0A2I4AQE4 E9GJ14 A7RYJ8 A0A326UA10 A0A0P5GAN0 A0A3Q1JKW6 A0A2W4L844 A0A3B4UPQ5 A0A3Q2PQ69 A0A3B4WLZ5 I3K9H9 A0A3Q3A601 A0A3Q4I2C5 F6TMG0 A0A336KLU8 W4XAC4 A0A3G8YJ63 A0A3Q3VP45 A0A2V9KNH4 A0A3Q2VX22 A0A1U7NUJ4 A0A3Q0T2Y0 A0A016QSQ7 A1L259 A0A3Q1CRA1 A0A3P8TT57 A0A3B3YTX9 W5M9S0 A7SCA1 A0A3P9Q469 M3XI16 M9Z162 A0A2I9CW92 A0A1S3NHQ1 Q4S568 A0A3P8WH42 A0A3B3VDI0 Q17JD3 A0A3P8WH61 E6ZIS3 A0A0P7WNR6 H3D593 A0A087XP72 A0A3B3HKS0 A0A3P9MAV8 A0A0A7KGT6 A0A2N5KC24 C3XUZ7 A0A147ALM4
K7J0V7 A0A2P8ZCT1 A0A0L7KQ70 A0A2H1WQ75 K1PA03 A0A2H1WDQ3 A0A3R5WDW9 T1EB70 A0A1Q3FQJ2 C3YZC5 B0WCJ1 A0A2M4AFM4 A0A2M4CUY6 A0A182Q522 A0A1Y1NGH6 A0A1D2MZ07 A0A2M4CV15 Q16ER5 A0A2M4C1G0 A0A0C9R4W1 A0A0P4XF24 A0A182PKU9 A0A0C9RRY6 A0A2M3ZII1 A0A182VTW3 U5EXQ5 A0A0P5GS61 Q1J3A0 A0A182UMZ0 A0A182WZE2 A0A182ICS5 A0A336KHC1 B0WCJ2 A0A3S2NV28 A0A0P6C9F4 A0A182NAY1 A0A182L661 A7UV21 A0A0P6IR48 A0A0U2U2L5 A0A1Y1NFW0 A0A3P9A277 A0A1S3H7Y6 Q0ZDF7 A0A226EKE3 A0A2I4AQE4 E9GJ14 A7RYJ8 A0A326UA10 A0A0P5GAN0 A0A3Q1JKW6 A0A2W4L844 A0A3B4UPQ5 A0A3Q2PQ69 A0A3B4WLZ5 I3K9H9 A0A3Q3A601 A0A3Q4I2C5 F6TMG0 A0A336KLU8 W4XAC4 A0A3G8YJ63 A0A3Q3VP45 A0A2V9KNH4 A0A3Q2VX22 A0A1U7NUJ4 A0A3Q0T2Y0 A0A016QSQ7 A1L259 A0A3Q1CRA1 A0A3P8TT57 A0A3B3YTX9 W5M9S0 A7SCA1 A0A3P9Q469 M3XI16 M9Z162 A0A2I9CW92 A0A1S3NHQ1 Q4S568 A0A3P8WH42 A0A3B3VDI0 Q17JD3 A0A3P8WH61 E6ZIS3 A0A0P7WNR6 H3D593 A0A087XP72 A0A3B3HKS0 A0A3P9MAV8 A0A0A7KGT6 A0A2N5KC24 C3XUZ7 A0A147ALM4
PDB
2O74
E-value=1.59564e-30,
Score=327
Ontologies
PATHWAY
GO
PANTHER
Topology
Subcellular location
Peroxisome
SignalP
Position: 1 - 20,
Likelihood: 0.873711
Length:
181
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.0621600000000001
Exp number, first 60 AAs:
0.06195
Total prob of N-in:
0.04371
outside
1 - 181
Population Genetic Test Statistics
Pi
193.958774
Theta
164.417443
Tajima's D
0.575117
CLR
0.673924
CSRT
0.537023148842558
Interpretation
Uncertain
