Gene

KWMTBOMO07899  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001185

Annotation

N-cetylglucosamine-6-phosphate_deacetylase_[Spodoptera_litura]

Location

Bomo_Chr13(-):9614405-9618918      View in EpiBrowser

Full name

N-acetylglucosamine-6-phosphate deacetylase      

Location in the cell

Cytoplasmic   Reliability : 2.951

CDS

ATGAAATCTAAATCAGGTTTAACTCGTTTTCACAATTGTTACATTCTTCGTGATCGTAAAATTATCAAAGAAGATTTATGGATACGAGATGGAAAAATCGAAAATCCTGAACGTGTTTTTTATGTGGAACAACTTGAATCAGACATCACAGTTGATTGCGAGGACCTACTTATTGCTCCCGGGTTCATTGACATTCAGATAAACGGTGGATGGGGTGTTGACTTCTCTAGAGATTCTGATAACATTGAAGAAGGCGTGGCTAAAGTTGCAAAGAATTTGTTAGCTCATGGAGTAACAGCATTTTGTCCTACGATGATTACATCAGATCAAGAAATTTATAGGCAAATATTACCAAGAATTAAGAAAACCCAAGGAAACAAAAATGGTGCTACAGTACTTGGAGTACATTTAGAAGGCCCATTTATAAGCCCTACCAAAAAGGGAGCTCATGTTGAGTCCTATATAAAAAATCCTCATAGGGGTATAGATACTATTAGAGAAGTATACGGTTCTTTGGATAATGTGGTAATAATCACACTAGCTCCAGAACTTCCAGGTTGTTTTGAAGCAATCAAGGATCTCACGAATCTTGGTATCAAAGTTGCTCTTGGACATTCCATTGCCAGTTTGGCAGAAGGCGAAAAGGCTGTCGAGTGCGGTGCTAATTTAATAACTCATCTCTTTAATGCAATGCTACCAGTAATCACAAAACTCTTCGGAACGACATCTTAG

Protein

MKSKSGLTRFHNCYILRDRKIIKEDLWIRDGKIENPERVFYVEQLESDITVDCEDLLIAPGFIDIQINGGWGVDFSRDSDNIEEGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKNGATVLGVHLEGPFISPTKKGAHVESYIKNPHRGIDTIREVYGSLDNVVIITLAPELPGCFEAIKDLTNLGIKVALGHSIASLAEGEKAVECGANLITHLFNAMLPVITKLFGTTS

Catalytic Activity

H2O + N-acetyl-D-glucosamine 6-phosphate = acetate + D-glucosamine 6-phosphate

Cofactor

a divalent metal cation

Similarity

Belongs to the metallo-dependent hydrolases superfamily. NagA family.
Belongs to the universal ribosomal protein uS11 family.

Uniprot

H9IVA5   A0A2H1W6Y2   S5GAZ8   A0A2A4J876   A0A2W1BTB6   I4DJ61   + More
A0A194QAC2   A0A194RI15   I4DRC2   A0A212FLN5   A0A0L7L1U4   A0A182JLI6   A0A2A3EKP6   A0A0B4J2M4   A0A182M5S2   A0A151ICY0   A0A195B8J4   A0A0L7R617   A0A084W6W9   F4WNM6   A0A182PA19   A0A158NY12   E2AFM4   A0A1B6EQN5   A0A195ECC4   A0A151XBY1   A0A195FW46   A0A1B6HSI2   Q7QBX3   W5JF47   A0A139WIQ9   A0A182K3S8   E0VY53   A0A182U7I7   A0A182Y7A4   A0A0P4W9N4   A0A182XID6   A0A2M4AMN1   A0A182RCV7   E2BX93   A0A182GIW6   A0A1B6G3U7   A0A182FR77   Q17I97   A0A026WSP8   A0A1Y1L6X7   A0A3L8DGS9   A0A232ETY6   A0A182VQ89   A0A1S4F1X7   K7J399   A0A1Y1LBY0   A0A3Q0IPR9   A0A1L8E1N9   A0A1B0CB00   A0A182N4M5   A0A3P8VLM2   A0A182HTC0   I3JSI9   I3JSJ0   A0A3P8VRX8   A0A1B0D4T6   A0A3Q2VKT6   A0A1J1IRB1   A0A154PQZ8   A0A1B0AFG4   C3ZSZ5   A0A1B6CCK2   A0A1B6M6N7   A0A3Q3C2I9   A0A1B0GFQ5   A0A2J7PFK9   A0A1A9VNC6   A0A3P9AW93   A0A3P8QA27   A0A1A9WHR8   A0A2U9CSF7   A0A3P8S8M9   A0A3Q3JXV3   H2RTS3   A0A3Q1G7C3   A0A3B4T4Z7   A0A336LUT2   A0A3Q1B018   A0A3S2Q4M1   K4FUW1   A0A1Q3FGT0   A0A3P8S953   A0A1A8CYW1   A0A3B4T568   A0A3Q1ETH1   A0A0N8EMR2   A0A3Q1BBH9   A0A3P9J1K6   A0A1S3I360   A0A3P9HFQ1   E9G0Q8   A0A3B5A4R6   B0WS55   A0A3Q3XP82  

EC Number

3.5.1.25

Pubmed

19121390    28756777    22651552    26354079    22118469    26227816    + More
24438588    21719571    21347285    20798317    12364791    14747013    17210077    20920257    23761445    18362917    19820115    20566863    25244985    26483478    17510324    24508170    28004739    30249741    28648823    20075255    24487278    25186727    18563158    21551351    23056606    17554307    21292972   

EMBL

BABH01000784    BABH01000785    ODYU01006735    SOQ48849.1    KC832291    AGQ53951.1    + More
NWSH01002427    PCG68327.1    KZ149978    PZC75876.1    AK401329    BAM17951.1    KQ459299    KPJ01945.1    KQ460205    KPJ16970.1    AK405059    BAM20462.1    AGBW02007761    OWR54609.1    JTDY01003645    KOB69229.1    AXCP01008967    KZ288219    PBC32288.1    AXCM01001115    KQ978048    KYM97798.1    KQ976565    KYM80514.1    KQ414648    KOC66315.1    ATLV01020999    ATLV01021000    KE525311    KFB45963.1    GL888237    EGI64219.1    ADTU01002870    GL439118    EFN67775.1    GECZ01029507    JAS40262.1    KQ979074    KYN22761.1    KQ982316    KYQ57820.1    KQ981215    KYN44542.1    GECU01030105    JAS77601.1    AAAB01008859    EAA08223.5    ADMH02001587    ETN61953.1    KQ971338    KYB27794.1    DS235843    EEB18309.1    GDRN01088807    GDRN01088806    JAI60769.1    GGFK01008734    MBW42055.1    GL451230    EFN79676.1    JXUM01012630    JXUM01012631    JXUM01012632    KQ560358    KXJ82845.1    GECZ01012654    JAS57115.1    CH477241    EAT46400.1    KK107109    EZA59057.1    GEZM01062888    GEZM01062881    JAV69433.1    QOIP01000008    RLU19516.1    NNAY01002197    OXU21830.1    GEZM01062883    JAV69435.1    GFDF01001456    JAV12628.1    AJWK01004691    APCN01000438    AERX01008199    AJVK01024863    CVRI01000058    CRL02688.1    KQ435066    KZC14336.1    GG666675    EEN44340.1    GEDC01026101    JAS11197.1    GEBQ01008387    JAT31590.1    CCAG010003444    NEVH01025655    PNF15120.1    CP026261    AWP19521.1    UFQT01000205    UFQT01001174    SSX21694.1    SSX29306.1    CM012444    RVE69951.1    JX053181    AFK11409.1    GFDL01008284    JAV26761.1    HADZ01019880    SBP83821.1    GDIQ01011572    JAN83165.1    GL732528    EFX87360.1    DS232064    EDS33674.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000037510    + More
UP000075880    UP000242457    UP000005203    UP000075883    UP000078542    UP000078540    UP000053825    UP000030765    UP000007755    UP000075885    UP000005205    UP000000311    UP000078492    UP000075809    UP000078541    UP000007062    UP000000673    UP000007266    UP000075881    UP000009046    UP000075902    UP000076408    UP000076407    UP000075900    UP000008237    UP000069940    UP000249989    UP000069272    UP000008820    UP000053097    UP000279307    UP000215335    UP000075920    UP000002358    UP000079169    UP000092461    UP000075884    UP000265120    UP000075840    UP000005207    UP000092462    UP000264840    UP000183832    UP000076502    UP000092445    UP000001554    UP000092444    UP000235965    UP000078200    UP000265160    UP000265100    UP000091820    UP000246464    UP000265080    UP000261600    UP000005226    UP000257200    UP000261420    UP000257160    UP000265200    UP000085678    UP000000305    UP000261400    UP000002320    UP000261620   

PRIDE

H9IVA5   

Pfam

PF01979   Amidohydro_1        + More
PF00411   Ribosomal_S11
PF03725   RNase_PH_C
PF01138   RNase_PH

Interpro

IPR011059   Metal-dep_hydrolase_composite        + More
IPR006680   Amidohydro-rel       
IPR003764   GlcNAc_6-P_deAcase       
IPR032466   Metal_Hydrolase       
IPR001971   Ribosomal_S11       
IPR036967   Ribosomal_S11_sf       
IPR018102   Ribosomal_S11_CS       
IPR015847   ExoRNase_PH_dom2       
IPR001247   ExoRNase_PH_dom1       
IPR027408   PNPase/RNase_PH_dom_sf       
IPR020568   Ribosomal_S5_D2-typ_fold       
IPR033100   Rrp45       
IPR036345   ExoRNase_PH_dom2_sf       

SUPFAM

SSF51556   SSF51556        + More
SSF51338   SSF51338       
SSF55666   SSF55666       
SSF54211   SSF54211       

Gene 3D

2.30.40.10     3.30.420.80     3.30.230.70    

CDD

cd00854  NagA
cd11368  RNase_PH_RRP45

ProteinModelPortal

H9IVA5   A0A2H1W6Y2   S5GAZ8   A0A2A4J876   A0A2W1BTB6   I4DJ61   + More
A0A194QAC2   A0A194RI15   I4DRC2   A0A212FLN5   A0A0L7L1U4   A0A182JLI6   A0A2A3EKP6   A0A0B4J2M4   A0A182M5S2   A0A151ICY0   A0A195B8J4   A0A0L7R617   A0A084W6W9   F4WNM6   A0A182PA19   A0A158NY12   E2AFM4   A0A1B6EQN5   A0A195ECC4   A0A151XBY1   A0A195FW46   A0A1B6HSI2   Q7QBX3   W5JF47   A0A139WIQ9   A0A182K3S8   E0VY53   A0A182U7I7   A0A182Y7A4   A0A0P4W9N4   A0A182XID6   A0A2M4AMN1   A0A182RCV7   E2BX93   A0A182GIW6   A0A1B6G3U7   A0A182FR77   Q17I97   A0A026WSP8   A0A1Y1L6X7   A0A3L8DGS9   A0A232ETY6   A0A182VQ89   A0A1S4F1X7   K7J399   A0A1Y1LBY0   A0A3Q0IPR9   A0A1L8E1N9   A0A1B0CB00   A0A182N4M5   A0A3P8VLM2   A0A182HTC0   I3JSI9   I3JSJ0   A0A3P8VRX8   A0A1B0D4T6   A0A3Q2VKT6   A0A1J1IRB1   A0A154PQZ8   A0A1B0AFG4   C3ZSZ5   A0A1B6CCK2   A0A1B6M6N7   A0A3Q3C2I9   A0A1B0GFQ5   A0A2J7PFK9   A0A1A9VNC6   A0A3P9AW93   A0A3P8QA27   A0A1A9WHR8   A0A2U9CSF7   A0A3P8S8M9   A0A3Q3JXV3   H2RTS3   A0A3Q1G7C3   A0A3B4T4Z7   A0A336LUT2   A0A3Q1B018   A0A3S2Q4M1   K4FUW1   A0A1Q3FGT0   A0A3P8S953   A0A1A8CYW1   A0A3B4T568   A0A3Q1ETH1   A0A0N8EMR2   A0A3Q1BBH9   A0A3P9J1K6   A0A1S3I360   A0A3P9HFQ1   E9G0Q8   A0A3B5A4R6   B0WS55   A0A3Q3XP82  

PDB

3IV8     E-value=3.23198e-25,     Score=283

KEGG

101738216    K01443 N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] | (RefSeq) putative N-acetylglucosa

PATHWAY

00520    Amino sugar and nucleotide sugar metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0005975   GO:0047419   GO:0008448   GO:0046872   GO:0006044   GO:0016810   GO:0006046   GO:0005840   GO:0006412   GO:0003735   GO:0000178   GO:0006396   GO:0016787   GO:0005515   GO:0006418   GO:0004819   GO:0006425   GO:0016876   GO:0043039  

Length:

243

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.07598

Exp number, first 60 AAs:

5e-05

Total prob of N-in:

0.06896

outside

1  -  243

 

 

Pi

42.066818

Theta

67.993604

Tajima's D

-1.331284

CLR

0.149941

CSRT

0.0810959452027399

Interpretation

Uncertain