Gene

KWMTBOMO07897  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001185

Annotation

N-cetylglucosamine-6-phosphate_deacetylase_[Spodoptera_litura]

Location

Bomo_Chr13(-):9606726-9608828      View in EpiBrowser

Full name

N-acetylglucosamine-6-phosphate deacetylase      

Location in the cell

Cytoplasmic   Reliability : 1.584 Extracellular   Reliability : 1.635

CDS

ATGTATAGCGAGCGGGCATACGGCCGCGAGAGTGACGTACCGTTCCATCATCGTGATCCAGGATTAGTAGGGTTACTAGCTTCTACGATGAAAAAACAAGTATATTATGGTATAATAGCTGATGGTATCCACACTCATCCAGCAGCGCTCAGAATAGCAAACAGAACTAATCCCGAAGGTTTAGTACTAGTAAGTGATGCAGTGCCAGCGCAGGGACTACCGGATGGTAACCATCGCATTGGACCGCAAATCGTGACGGTAGAAGACGGTTGCGCTTACGTCACTGGAACGAAAACCCTCTGTGGAAGCACTACTGCCCTGGACTCCTGTATTGTGAAATTTAAAGACTCGATTGAATGTAGCTTGGAATATGCATTGGAAGCAGCCTCATTACATCCGGCTAAGGCTTTAGGAATTGATGACAAGAAAGGGAATTTAAACTTTGACAGTGACGCTGACTTCGTAATACTTCACCCTAAAACATTGAAAGTTCAATCCACCTGGATAGCTGGAGAATGTGTATATAAATGCCAGAACTAA

Protein

MYSERAYGRESDVPFHHRDPGLVGLLASTMKKQVYYGIIADGIHTHPAALRIANRTNPEGLVLVSDAVPAQGLPDGNHRIGPQIVTVEDGCAYVTGTKTLCGSTTALDSCIVKFKDSIECSLEYALEAASLHPAKALGIDDKKGNLNFDSDADFVILHPKTLKVQSTWIAGECVYKCQN

Description

Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.

Catalytic Activity

H2O + N-acetyl-D-glucosamine 6-phosphate = acetate + D-glucosamine 6-phosphate

Cofactor

a divalent metal cation

Similarity

Belongs to the metallo-dependent hydrolases superfamily. NagA family.
Belongs to the universal ribosomal protein uS11 family.

Keywords

Carbohydrate metabolism   Complete proteome   Hydrolase   Metal-binding   Reference proteome  

Feature

chain  N-acetylglucosamine-6-phosphate deacetylase

Uniprot

H9IVA5   A0A2W1BTB6   A0A2A4J876   S5GAZ8   A0A212FLN5   S4NND0   + More
I4DRC2   I4DJ61   A0A194RI15   A0A2H1W6Y2   A0A194QAC2   A0A0L7L1U4   A0A2D4GE62   A0A182VGP9   A0A1B6JGT0   A0A182SHB0   A0A2D4Q028   Q7QBX3   A0A182PA19   A0A182FR77   A0A182XID6   A0A2M4AMN1   W5JF47   A0A1L8E1N9   A0A2D4GEC7   A0A182GIW6   A0A182K3S8   B4GV30   A0A1B6M6N7   A0A1S4F1X7   Q17I97   A0A182U7I7   A0A1Q3FGT0   A0A182JLI6   W8C6X2   A0A0A1WZU0   A0A0K8WLL3   A0A2D4IPM1   A0A1B0CB00   A0A1B6G3U7   Q29GW7   A0A1J1IRB1   A0A0K8RSL3   A0A2J7PFL1   E2AFM4   A0A158NY12   A0A1B0D4T6   A0A195B8J4   G3I2T8   A0A151ICY0   A0A195FW46   F4WNM6   A0A034VT64   A0A182HTC0   A0A2C9K4U3   A0A195ECC4   A0A151XBY1   A0A2C9K4S2   A0A182M5S2   B0WS55   A0A1B6CLI3   A0A0C9R8Z0   A0A0L7R617   A0A3B0JXJ4   A0A1W4VF90   A0A182VQ89   A0A2J7PFM1   B3NWH2   A0A0K8WIC2   B4NCN7   J9JKI9   A0A139WIQ9   A0A0Q9XFY2   A0A182Y7A4   A0A0Q9XQE4   A0A3Q3N7S5   A0A182RCV7   A0A2J7PFK9   A0A061I330   U3JQK5   X2JFY0   Q9VR81   A0A1B6JIX3   A0A0B4J2M4   A0A336LUT2   A0A091UIU3   A0A2Y9DF13   E1JJR9   B4PY15   A0A226MVY0   A0A1I8NLQ4   A0A0P4WHL1   G3TV02   B4L7W7   A0A1A6GDM9   G3TG18   K1QXA4   A0A154PQZ8   A0A091WH03   I3MKZ4  

EC Number

3.5.1.25

Pubmed

19121390    28756777    22118469    23622113    22651552    26354079    + More
26227816    12364791    14747013    17210077    20920257    23761445    26483478    17994087    17510324    24495485    25830018    15632085    25727380    20798317    21347285    21804562    21719571    25348373    15562597    18362917    19820115    25244985    23929341    29704459    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    17550304    18057021    22992520   

EMBL

BABH01000784    BABH01000785    KZ149978    PZC75876.1    NWSH01002427    PCG68327.1    + More
KC832291    AGQ53951.1    AGBW02007761    OWR54609.1    GAIX01012304    JAA80256.1    AK405059    BAM20462.1    AK401329    BAM17951.1    KQ460205    KPJ16970.1    ODYU01006735    SOQ48849.1    KQ459299    KPJ01945.1    JTDY01003645    KOB69229.1    IACJ01123622    LAA58061.1    GECU01013216    GECU01009322    JAS94490.1    JAS98384.1    IACN01100870    LAB63567.1    AAAB01008859    EAA08223.5    GGFK01008734    MBW42055.1    ADMH02001587    ETN61953.1    GFDF01001456    JAV12628.1    IACJ01123621    LAA58058.1    JXUM01012630    JXUM01012631    JXUM01012632    KQ560358    KXJ82845.1    CH479192    EDW26567.1    GEBQ01008387    JAT31590.1    CH477241    EAT46400.1    GFDL01008284    JAV26761.1    AXCP01008967    GAMC01000877    JAC05679.1    GBXI01009950    JAD04342.1    GDHF01000589    JAI51725.1    IACK01119929    LAA86158.1    AJWK01004691    GECZ01012654    JAS57115.1    CH379064    EAL31992.2    CVRI01000058    CRL02688.1    GBKC01002274    JAG43796.1    NEVH01025655    PNF15119.1    GL439118    EFN67775.1    ADTU01002870    AJVK01024863    KQ976565    KYM80514.1    JH001143    EGW09759.1    KQ978048    KYM97798.1    KQ981215    KYN44542.1    GL888237    EGI64219.1    GAKP01012431    JAC46521.1    APCN01000438    KQ979074    KYN22761.1    KQ982316    KYQ57820.1    AXCM01001115    DS232064    EDS33674.1    GEDC01023157    JAS14141.1    GBYB01003256    JAG73023.1    KQ414648    KOC66315.1    OUUW01000003    SPP78489.1    PNF15118.1    CH954180    EDV46792.1    GDHF01001520    JAI50794.1    CH964239    EDW82596.1    ABLF02029453    KQ971338    KYB27794.1    CH933814    KRG07430.1    KRG07428.1    PNF15120.1    KE682131    RAZU01000243    ERE67775.1    RLQ62918.1    AGTO01020847    AE014298    AHN59958.1    AY089672    GECU01008460    JAS99246.1    UFQT01000205    UFQT01001174    SSX21694.1    SSX29306.1    KL409574    KFQ90631.1    ACZ95338.1    CM000162    EDX02987.1    MCFN01000402    OXB59280.1    GDIP01255160    LRGB01001581    JAI68241.1    KZS11258.1    EDW05542.1    LZPO01097222    OBS64356.1    JH818609    EKC35804.1    KQ435066    KZC14336.1    KK735490    KFR14400.1    AGTP01095340   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000053268    UP000037510    + More
UP000075903    UP000075901    UP000007062    UP000075885    UP000069272    UP000076407    UP000000673    UP000069940    UP000249989    UP000075881    UP000008744    UP000008820    UP000075902    UP000075880    UP000092461    UP000001819    UP000183832    UP000235965    UP000000311    UP000005205    UP000092462    UP000078540    UP000001075    UP000078542    UP000078541    UP000007755    UP000075840    UP000076420    UP000078492    UP000075809    UP000075883    UP000002320    UP000053825    UP000268350    UP000192221    UP000075920    UP000008711    UP000007798    UP000007819    UP000007266    UP000009192    UP000076408    UP000261640    UP000075900    UP000030759    UP000273346    UP000016665    UP000000803    UP000005203    UP000053283    UP000248480    UP000002282    UP000198323    UP000095300    UP000076858    UP000007646    UP000092124    UP000005408    UP000076502    UP000053605    UP000005215   

PRIDE

H9IVA5    Q9VR81   

Pfam

PF01979   Amidohydro_1        + More
PF03725   RNase_PH_C
PF01138   RNase_PH
PF00411   Ribosomal_S11
PF04500   FLYWCH

Interpro

IPR011059   Metal-dep_hydrolase_composite        + More
IPR006680   Amidohydro-rel       
IPR003764   GlcNAc_6-P_deAcase       
IPR032466   Metal_Hydrolase       
IPR020568   Ribosomal_S5_D2-typ_fold       
IPR033100   Rrp45       
IPR036345   ExoRNase_PH_dom2_sf       
IPR015847   ExoRNase_PH_dom2       
IPR001247   ExoRNase_PH_dom1       
IPR027408   PNPase/RNase_PH_dom_sf       
IPR001971   Ribosomal_S11       
IPR036967   Ribosomal_S11_sf       
IPR018102   Ribosomal_S11_CS       
IPR007588   Znf_FLYWCH       

SUPFAM

SSF51556   SSF51556        + More
SSF51338   SSF51338       
SSF54211   SSF54211       
SSF55666   SSF55666       

Gene 3D

2.30.40.10     3.30.230.70     3.30.420.80    

CDD

cd00854  NagA
cd11368  RNase_PH_RRP45

ProteinModelPortal

H9IVA5   A0A2W1BTB6   A0A2A4J876   S5GAZ8   A0A212FLN5   S4NND0   + More
I4DRC2   I4DJ61   A0A194RI15   A0A2H1W6Y2   A0A194QAC2   A0A0L7L1U4   A0A2D4GE62   A0A182VGP9   A0A1B6JGT0   A0A182SHB0   A0A2D4Q028   Q7QBX3   A0A182PA19   A0A182FR77   A0A182XID6   A0A2M4AMN1   W5JF47   A0A1L8E1N9   A0A2D4GEC7   A0A182GIW6   A0A182K3S8   B4GV30   A0A1B6M6N7   A0A1S4F1X7   Q17I97   A0A182U7I7   A0A1Q3FGT0   A0A182JLI6   W8C6X2   A0A0A1WZU0   A0A0K8WLL3   A0A2D4IPM1   A0A1B0CB00   A0A1B6G3U7   Q29GW7   A0A1J1IRB1   A0A0K8RSL3   A0A2J7PFL1   E2AFM4   A0A158NY12   A0A1B0D4T6   A0A195B8J4   G3I2T8   A0A151ICY0   A0A195FW46   F4WNM6   A0A034VT64   A0A182HTC0   A0A2C9K4U3   A0A195ECC4   A0A151XBY1   A0A2C9K4S2   A0A182M5S2   B0WS55   A0A1B6CLI3   A0A0C9R8Z0   A0A0L7R617   A0A3B0JXJ4   A0A1W4VF90   A0A182VQ89   A0A2J7PFM1   B3NWH2   A0A0K8WIC2   B4NCN7   J9JKI9   A0A139WIQ9   A0A0Q9XFY2   A0A182Y7A4   A0A0Q9XQE4   A0A3Q3N7S5   A0A182RCV7   A0A2J7PFK9   A0A061I330   U3JQK5   X2JFY0   Q9VR81   A0A1B6JIX3   A0A0B4J2M4   A0A336LUT2   A0A091UIU3   A0A2Y9DF13   E1JJR9   B4PY15   A0A226MVY0   A0A1I8NLQ4   A0A0P4WHL1   G3TV02   B4L7W7   A0A1A6GDM9   G3TG18   K1QXA4   A0A154PQZ8   A0A091WH03   I3MKZ4  

PDB

2VHL     E-value=1.08487e-16,     Score=207

KEGG

101738216    K01443 N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] | (RefSeq) putative N-acetylglucosa

GO

GO:0005975   GO:0047419   GO:0008448   GO:0046872   GO:0006044   GO:0016810   GO:0006046   GO:0006396   GO:0000178   GO:0005840   GO:0006412   GO:0003735   GO:0016787   GO:0005515   GO:0006418   GO:0004819   GO:0006425   GO:0016876   GO:0043039  

Length:

179

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.05367

Exp number, first 60 AAs:

0.05323

Total prob of N-in:

0.27298

outside

1  -  179

 

 

Pi

58.111085

Theta

64.253311

Tajima's D

0.092858

CLR

0.634029

CSRT

0.391980400979951

Interpretation

Uncertain