Gene

KWMTBOMO07879

Pre Gene Modal

BGIBMGA001191

Annotation

PREDICTED:_bestrophin-4-like_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr13(-):9031978-9060089      View in EpiBrowser

Full name

Bestrophin homolog      

Location in the cell

PlasmaMembrane   Reliability : 3.389

CDS

ATGACTGTGACTTACACCGGTGAAGTAGCAACTTGCCGAGGTTTTGGGACTTTTTTAAAAGTTTTATACAGATGGCGCGGCAGTATATACAAACTGGTGTGGCTAGATCTTCTAGTTTTCCTGCTTTTGTATTATATACTCAATTTAACATATCGCTTACTTCTAGATGAAAATGCGAAGAGAACGTTCGAAGGAATAGTGAATTATTGTCATTTCCACGGGAATGTGATCCCTTTGTCGTTCGTACTAGGTTTCTATGTTACTGTAGTAATGAACCGCTGGTGGAATCAATACACAACGATACCGTGGCCTGATTCGATTGCCGTCTTCGTGTCAGCCACGATACACGGACAGGATGAACGTGGGAGGTTGATGCGTCGGACAATCGTGCGCTATGTATGTCTCTGTCTGACGATGGTGTTAACGATGATATCTCCAAGAGTCAAGAAGCGTTTTCCGACGCTCGACAACTTTACCGAGGCCGGTATAATGAATGAAAATGAAAAATCAATACTTAACAATATGAATGAAAAATTTCCAAAGACAACGAAGCACTGGTTACCAATAGTGTGGGCGGCTAGTATTGTGACGAGGGCCCGTAAGGAGGGCCGAATAAGAGACGATTTTGCCGTTAAAACTATAATAGATGAATTAAATAAATTTAGAGCACAAGCGGGACTTCTCCTCAGTTATGATACCATAAGCGTACCATTAGTTTACACTCAGGTAGTGACAATTGCTGTATACTCGTATTTCATAACGTCTGCACTCGGCAGTCAGTGGGTCGATAACAAAGTGCAGTCTGCTGAATCAACGTACATTAGTAATATTGATCTCTATTTCCCGATATTCAGTACGTTAGAATTCTTCTTCTATATGGGCTGGTTGAAAGTAGCCGAATCTCTTATAAATCCATTTGGTGAGGACGACGATGATTTCGAAGTTAACTGGATAATCGATAGAGATTTACAGGTTTCATACATGATAGTCGATGAGATGCACCATGAGCATCCCGAGTTGGTGAAAGATCAGTACTGGGACGAGGTGTTCCCGTCAGAGTTGCCGTACACGTTAGCCACGGAGAACCAGCGCGAGGAGCATCCGGAGCCTTCGACAGCTCGCGTGGCGGTGCCGGTCCGGCAGCGCAGCATGGTCTTGACCGCGCCCTCGTCTGTCAAGATCGACGAGATGGTCCCCTCCAACACCGTGAGTTACAAGTTCGCCCCGCCAGAGCAAATTCAAATGAGCGACGACGCGCAGTCTGGCATACACTTCATCGTCCACCGCGGAAGCAGTAAGCGAAAGAAGGAGGAAAGGAACTCTATGGGCTCCTCTAACTCGATGGCGTCGCTACAGCAAACGCCCATGAACAGAACTAATTCTGTCACATCGATGCTCAAAAGACTGTTCTCCAAGGAAGAGCAACGGCAACCGACTACTGCCTCTGTCACTGCCACGCAGACTGATAGCGGTAACCGTTTCACGATTTCGGCGAGCAACCCGACCTTGAACAAGCCGGCCACGGCGGGCGGCAGCATGAAGATCGCGAATGAAGTCATCGAAGAGGTCGACGAACAGGCCACCATCACGAGTATGGGCAAACGACCCGACAACAGGCCGACTGCGATGAGTTTGTTTGCGCAAAAACCTCTCCCGCCCAGTGATCCAGTTAACGTGCCGTCACGAAATTCGAATCACAGCTCCAAGGAAGACAGTCGGTTGTCCCGCTCGGCGCCGAATCAGTGGGGCGGCGAGCGCGACGACGAGCGAGACGACAAGAGTCCGACGGCGCGCTCGCTCACCGCGCGGGGCTCGTTCGCCGACATCGACGACGAGCGGCGGCCGCGTCTCGACAGCGACGTCGGCGCCTCGCTCAGCGCTGCCGGCAGCCAGACACTCATCGATGATGTGGATGGGGAGGAAGAACCCGATATAGATGACTTCAACCGGCTCAGAAGTATAAGAGAGCAGCACCGAAGAGATAAATATTTACAGAAACTAATGGCTCGGTCTGTTAGTGCTCAACAGCGCACAGGCAGTGGTGAAATATTAGACAATGATCTATTGTTAGAAGACCTACTAATCCAATCAGGAGCGTTGAAGAAAGAAGAGAACCATATAAATGGGTCAAAAGAAGACACAACTTGA

Protein

MTVTYTGEVATCRGFGTFLKVLYRWRGSIYKLVWLDLLVFLLLYYILNLTYRLLLDENAKRTFEGIVNYCHFHGNVIPLSFVLGFYVTVVMNRWWNQYTTIPWPDSIAVFVSATIHGQDERGRLMRRTIVRYVCLCLTMVLTMISPRVKKRFPTLDNFTEAGIMNENEKSILNNMNEKFPKTTKHWLPIVWAASIVTRARKEGRIRDDFAVKTIIDELNKFRAQAGLLLSYDTISVPLVYTQVVTIAVYSYFITSALGSQWVDNKVQSAESTYISNIDLYFPIFSTLEFFFYMGWLKVAESLINPFGEDDDDFEVNWIIDRDLQVSYMIVDEMHHEHPELVKDQYWDEVFPSELPYTLATENQREEHPEPSTARVAVPVRQRSMVLTAPSSVKIDEMVPSNTVSYKFAPPEQIQMSDDAQSGIHFIVHRGSSKRKKEERNSMGSSNSMASLQQTPMNRTNSVTSMLKRLFSKEEQRQPTTASVTATQTDSGNRFTISASNPTLNKPATAGGSMKIANEVIEEVDEQATITSMGKRPDNRPTAMSLFAQKPLPPSDPVNVPSRNSNHSSKEDSRLSRSAPNQWGGERDDERDDKSPTARSLTARGSFADIDDERRPRLDSDVGASLSAAGSQTLIDDVDGEEEPDIDDFNRLRSIREQHRRDKYLQKLMARSVSAQQRTGSGEILDNDLLLEDLLIQSGALKKEENHINGSKEDTT

Description

Forms chloride channels.

Similarity

Belongs to the bestrophin family.

Uniprot

I6YK90   A0A2A4JZF4   A0A2A4JXZ1   A0A2A4JZR5   I6YTA0   A0A194RHZ4   + More
A0A2H1V5Z8   A0A194QAD6   A0A2A4JZP9   A0A212FDR1   H9IVB1   S4P8M3   A0A1J1J3H6   A0A1L8DEZ2   A0A1I8NTT4   A0A1L8DF58   A0A182RR12   A0A182W2E5   A0A182N3L5   A0A1I8NTS9   A0A182QNE1   A0A182L4L9   A0A182VLV0   A0A182P6W7   A0A182HH56   A0A1I8NTS7   A0A1I8NTS6   A0A1A9Z762   A0A1B0FEG7   A0A1A9UX44   A0A1I8NTT1   A0A1I8NTS5   A0A1A9Y607   Q7PZ58   B4LWD6   B3LW14   A0A0L0CH86   B7Z0U6   Q9V3J6   A0A0P8YJY3   A0A1I8NFW8   A0A3B0K331   A0A1I8NTR7   W5J6I9   A0A0Q9WDV2   B4K5I2   A0A2M4AKJ1   A0A0Q9WP48   A0A3B0KR61   A0A0P8ZWZ0   B4HJ86   B4PKM1   A0A0B4K651   A0A0R1E224   A0A0B4KGQ2   A0A0Q9X4D5   A0A182FVT3   A0A1W4U8Y6   A0A0Q9WXV5   A0A0P8XWV3   A0A1I8NFV5   A0A1I8NTT2   A0A1W4UK44   B4NFF2   A0A1Q3G0C8   A0A182HC67   A0A1B0ASL6   B3P4K3   A0A0Q9WPW6   A0A0Q9X9U7   A0A336LW06   A0A1W4UK78   A0A3B0K4U5   A0A1I8NFV7   A0A0Q9X4F9   A0A0R1E7N8   A0A1W4U8C5   A0A034VHS1   A0A0R1E2I5   A0A0Q9X691   Q29AK3   A0A034VEC7   A0A0Q9WW91   Q17G96   Q20C62   A0A023EVG7   A0A0A1WPS8   A0A084WJ31   A0A1I8NFW5   B4JIL3   A0A034VJD8   A0A034VGL9   A0A023F417   A0A1B0GKY5   E2ART8   A0A0K8W3D4   A0A1B6MIT8   A0A0A9XZ80   A0A146LQ26   A0A026WDM0  

Pubmed

23300744    26354079    22118469    19121390    23622113    20966253    + More
12364791    14747013    17210077    17994087    26108605    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25315136    20920257    23761445    18057021    17550304    26483478    25348373    15632085    17510324    16507169    24945155    25830018    24438588    25474469    20798317    25401762    26823975    24508170   

EMBL

JQ968534    AFN57624.1    NWSH01000371    PCG76893.1    PCG76891.1    PCG76892.1    + More
JQ968533    AFN57623.1    KQ460205    KPJ16950.1    ODYU01000854    SOQ36248.1    KQ459299    KPJ01960.1    PCG76890.1    AGBW02009000    OWR51889.1    BABH01000826    GAIX01007212    JAA85348.1    CVRI01000069    CRL07005.1    GFDF01009068    JAV05016.1    GFDF01009067    JAV05017.1    AXCN02001106    APCN01002389    CCAG010019281    CCAG010019282    AAAB01008986    EAA00042.3    CH940650    EDW66573.1    CH902617    EDV41547.1    JRES01000409    KNC31567.1    AE014297    ACL83492.1    AF218817    AY061546    AY515709    AAF32327.1    AAF54503.1    AAL29094.1    AAR99659.1    KPU79238.1    OUUW01000013    SPP87723.1    ADMH02001988    ETN60072.1    KRF82812.1    KRF82813.1    CH933806    EDW14019.1    GGFK01007946    MBW41267.1    KRF82815.1    SPP87721.1    KPU79240.1    CH480815    EDW42758.1    CM000160    EDW96780.1    AFH06336.1    KRK03334.1    AGB95834.1    CH964251    KRF99718.1    KRG00809.1    KRG00811.1    KRG00812.1    KRG00814.1    KPU79237.1    KPU79239.1    EDW83019.1    GFDL01001813    JAV33232.1    JXUM01032902    JXUM01032903    JXUM01032904    JXUM01032905    JXUM01032906    JXUM01032907    KQ560970    KXJ80175.1    JXJN01002867    JXJN01002868    JXJN01002869    CH954181    EDV49656.1    KRF82814.1    KRG00808.1    UFQT01000184    SSX21231.1    SPP87722.1    KRG00810.1    KRK03335.1    GAKP01017295    JAC41657.1    KRK03333.1    KRF99719.1    CM000070    EAL27346.3    GAKP01017301    JAC41651.1    KRF99720.1    CH477264    EAT45610.1    DQ378293    ABD64823.1    GAPW01000596    JAC13002.1    GBXI01016038    GBXI01013233    JAC98253.1    JAD01059.1    ATLV01023968    KE525347    KFB50225.1    CH916369    EDV93094.1    GAKP01017299    JAC41653.1    GAKP01017303    JAC41649.1    GBBI01002497    JAC16215.1    AJWK01033955    AJWK01033956    AJWK01033957    AJWK01033958    GL442170    EFN63856.1    GDHF01006703    JAI45611.1    GEBQ01004110    JAT35867.1    GBHO01018370    GDHC01004583    JAG25234.1    JAQ14046.1    GDHC01008646    JAQ09983.1    KK107273    EZA53781.1   

Proteomes

UP000218220    UP000053240    UP000053268    UP000007151    UP000005204    UP000183832    + More
UP000095300    UP000075900    UP000075920    UP000075884    UP000075886    UP000075882    UP000075903    UP000075885    UP000075840    UP000092445    UP000092444    UP000078200    UP000092443    UP000007062    UP000008792    UP000007801    UP000037069    UP000000803    UP000095301    UP000268350    UP000000673    UP000009192    UP000001292    UP000002282    UP000007798    UP000069272    UP000192221    UP000069940    UP000249989    UP000092460    UP000008711    UP000001819    UP000008820    UP000030765    UP000001070    UP000092461    UP000000311    UP000053097   

PRIDE

H9IVB1    B7Z0U6    Q9V3J6   

Pfam

PF01062   Bestrophin

Interpro

IPR000615   Bestrophin        + More
IPR021134   Bestrophin/UPF0187       

ProteinModelPortal

I6YK90   A0A2A4JZF4   A0A2A4JXZ1   A0A2A4JZR5   I6YTA0   A0A194RHZ4   + More
A0A2H1V5Z8   A0A194QAD6   A0A2A4JZP9   A0A212FDR1   H9IVB1   S4P8M3   A0A1J1J3H6   A0A1L8DEZ2   A0A1I8NTT4   A0A1L8DF58   A0A182RR12   A0A182W2E5   A0A182N3L5   A0A1I8NTS9   A0A182QNE1   A0A182L4L9   A0A182VLV0   A0A182P6W7   A0A182HH56   A0A1I8NTS7   A0A1I8NTS6   A0A1A9Z762   A0A1B0FEG7   A0A1A9UX44   A0A1I8NTT1   A0A1I8NTS5   A0A1A9Y607   Q7PZ58   B4LWD6   B3LW14   A0A0L0CH86   B7Z0U6   Q9V3J6   A0A0P8YJY3   A0A1I8NFW8   A0A3B0K331   A0A1I8NTR7   W5J6I9   A0A0Q9WDV2   B4K5I2   A0A2M4AKJ1   A0A0Q9WP48   A0A3B0KR61   A0A0P8ZWZ0   B4HJ86   B4PKM1   A0A0B4K651   A0A0R1E224   A0A0B4KGQ2   A0A0Q9X4D5   A0A182FVT3   A0A1W4U8Y6   A0A0Q9WXV5   A0A0P8XWV3   A0A1I8NFV5   A0A1I8NTT2   A0A1W4UK44   B4NFF2   A0A1Q3G0C8   A0A182HC67   A0A1B0ASL6   B3P4K3   A0A0Q9WPW6   A0A0Q9X9U7   A0A336LW06   A0A1W4UK78   A0A3B0K4U5   A0A1I8NFV7   A0A0Q9X4F9   A0A0R1E7N8   A0A1W4U8C5   A0A034VHS1   A0A0R1E2I5   A0A0Q9X691   Q29AK3   A0A034VEC7   A0A0Q9WW91   Q17G96   Q20C62   A0A023EVG7   A0A0A1WPS8   A0A084WJ31   A0A1I8NFW5   B4JIL3   A0A034VJD8   A0A034VGL9   A0A023F417   A0A1B0GKY5   E2ART8   A0A0K8W3D4   A0A1B6MIT8   A0A0A9XZ80   A0A146LQ26   A0A026WDM0  

PDB

6N28     E-value=4.08996e-95,     Score=891

KEGG

101739787    K22204 bestrophin, other | (RefSeq) bestrophin-4-like

GO

GO:0005886   GO:0005254   GO:0034707   GO:0016021   GO:0006884   GO:0009992   GO:0072320   GO:0005887   GO:0006821   GO:0005229  

PANTHER

PTHR10736  

Subcellular location

Cell membrane  

Length:

715

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

103.87683

Exp number, first 60 AAs:

22.59616

Total prob of N-in:

0.87224

POSSIBLE N-term signal

sequence

inside

1  -  31

TMhelix

32  -  54

outside

55  -  68

TMhelix

69  -  91

inside

92  -  127

TMhelix

128  -  145

outside

146  -  715

 

 

Pi

145.448597

Theta

146.114492

Tajima's D

-0.629992

CLR

186.854393

CSRT

0.211439428028599

Interpretation

Uncertain