Gene

KWMTBOMO07874  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001194

Annotation

PREDICTED:_probable_glutamine--tRNA_ligase_[Bombyx_mori]

Location

Bomo_Chr13(-):8953748-8962749      View in EpiBrowser

Full name

Probable glutamine--tRNA ligase      

Alternative Name

Glutaminyl-tRNA synthetase

Location in the cell

Cytoplasmic   Reliability : 3.546

CDS

ATGACACCTGAAGAAATAGTTGAACGATTTAAACTCCTTGGTTTAAACGAGCAAAAAGCCAAGGAAACACTGAAAAATGCGAATGTTACCAAAGTATTGCTTGCGGCGTTAGATGAGGTGCAATTGCAGTCGCTTCCACTTGGTGCAGGCATTTTGATTTACCATCTAGCTACCAAAATCAAACCTCAAACTATGAGCAAGTTAAACTTTATTTGCCAATATATTGCATCAGGAAAACTGGATTCAACGTTGCGAGTAGACGCAGCATTGGACTACCTTCTTGGCAATATTAATGAAGCTAATGTAAATATTGAGGAATTTGAAAAAGCCTGTGGTGTTGGTGTTATTGTAACACCCGAACAAGTAGAGCAAGCAGTAGAAAAACATATGGTAAAATACAAGCAGGAACTATTAGAAAAGAGATACAGGTTCAACTCTGGTATAATCATGCAGGCTGTCAGGGCTGATCTAACTTGGGCAGATGGTAAAGCTATAAAAAGTGAAGTGGATGTACAGATCTTCGATTTATTGGGACCTAAGACTGAGGCTGATCTGGCTCCAGTTCCTAAAGCCAAGAAAGAAGCAAAGGCTGGTGATACAACAAAAAAATCAAAAAAGGAAGAAACAAAAGTCTCAAAACAAGAAAATGTTGAATCTTCAGAAGATATTGGTGGAGCAACCAGTATATCAGAACTAATGAAGAAGCTCCCCTTTCATGCACCAGGGGAGAATTATAAGAGCGATGGCTATGTGGTCACATCTCATACAAAACGATTGCTTGAAGAACATCTAAAGATAACTGGAGGAAAAGTTAGAACAAGATTTCCCCCTGAACCTAATGGAATTTTACACATTGGACATGCTAAGGCAATTAATATAAACTTTGGATATGCTGCAGCTCATGACGGTGTATGTTTCTTAAGATATGATGATACAAATCCTGAGAAAGAGGAGGAGAAGTTTTTTATTGGTATCAAAGACATGGTGGAATGGCTGGGTTATAAGCCATACAAAATTACACATTCATCTGATTATTTTGATCAGCTTTATGAATGGGCCATTCAGTTGATAAAAAAGGACTTGGCCTATGTATGCCATCAGAAGTCTGAAGATATAAAAGGATTCAATCCACCTCCGTCACCGTGGAGAATCAGGCCAATTGAAGAAAGTTTGCAGTTGTTTGAGGACATGAAAAATGGTAAAATTGATGAAGGGGATGCAACATTAAGAATGAAAATCACACTAGAAGAAGGGAAGCAGGATCCTGTAGCCTACAGAATAAGATTTAAGCCACATCATCGCACTGGAAATAAATGGTGCATCTACCCTACATATGATTATACCCACTGCCTATGTGACAGCATAGAACATATCACACACTCTCTTTGTACTAAGGAATTTCAATCACGAAGATCTTCATACTACTGGTTGTGCAATGCGCTTGGTATTTACTGTCCAGTACAATGGGAATATGGCAGACTAAATGTGAATTACACTGTCGTTTCCAAAAGAAAAATAGCGAAACTCATAGAAGAGGGTATTGTTAATGACTGGGACGACCCGCGCCTGTACACGCTGAGCGCGTTGCGGCGCGGCGGCGTGCCAGCGGCGGCGGTGAACGCGTTCTGCGCGGCGCTGGGCGTGACGGGCGCGCTCGGTGCCGTGGACCCCGCGCTGCTGCACGCCGCCGTGCGCGACCACCTCAACGTCACCGCGCCCAGAGCTATGGTAGTACTGGAACCATTAAAGATAAGAATAGTGAATTTCCCAAGCGAACAGCCTATATCGATACAAGTACCCGATTTTCCCAGTGAACCAGAAAGAGGTTCGCACTCAGTTACATTCGATAAGGTTATTTATATTGAAGCGACGGACTTCAAGGAAGAAATGGAGAAGGGCTACCGCCGATTGACACCCACACAGTCGGTCGGTTTGAGGCACGCCGGCTACGTAATTAAGGTATCTAAAGTCATAAAAGATCCGAGCGGTAAAGTATTGGAGCTGGAATGCACGGCCGAATCGACGGATTCGTCAGAGAAACCTAAAGCATTTATTCATTGGGTCTCCGAACCAATATCAATCGAGGTCAGGCTGTACGAACCACTATTTAAACACAAGAACCCAGAGGATCCCAACGAGGTTCCAGGTGGTTTCCTTTCCGACTGTCGTGACGATACCCTGAAGGTAATGGAAGCTTACGCCGACTCTTCAATCAAGGGTGCCAAAGTCTACGACAAGTTCCAGTTCGAGAGGATAGGATTTTTCTCCGTGGACCCAGACTCGAGTCAAACACACATGGTTTTCAACAGAACGGTCTCTCTGAAGGAAGACACCGGGAAATAA

Protein

MTPEEIVERFKLLGLNEQKAKETLKNANVTKVLLAALDEVQLQSLPLGAGILIYHLATKIKPQTMSKLNFICQYIASGKLDSTLRVDAALDYLLGNINEANVNIEEFEKACGVGVIVTPEQVEQAVEKHMVKYKQELLEKRYRFNSGIIMQAVRADLTWADGKAIKSEVDVQIFDLLGPKTEADLAPVPKAKKEAKAGDTTKKSKKEETKVSKQENVESSEDIGGATSISELMKKLPFHAPGENYKSDGYVVTSHTKRLLEEHLKITGGKVRTRFPPEPNGILHIGHAKAININFGYAAAHDGVCFLRYDDTNPEKEEEKFFIGIKDMVEWLGYKPYKITHSSDYFDQLYEWAIQLIKKDLAYVCHQKSEDIKGFNPPPSPWRIRPIEESLQLFEDMKNGKIDEGDATLRMKITLEEGKQDPVAYRIRFKPHHRTGNKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQSRRSSYYWLCNALGIYCPVQWEYGRLNVNYTVVSKRKIAKLIEEGIVNDWDDPRLYTLSALRRGGVPAAAVNAFCAALGVTGALGAVDPALLHAAVRDHLNVTAPRAMVVLEPLKIRIVNFPSEQPISIQVPDFPSEPERGSHSVTFDKVIYIEATDFKEEMEKGYRRLTPTQSVGLRHAGYVIKVSKVIKDPSGKVLELECTAESTDSSEKPKAFIHWVSEPISIEVRLYEPLFKHKNPEDPNEVPGGFLSDCRDDTLKVMEAYADSSIKGAKVYDKFQFERIGFFSVDPDSSQTHMVFNRTVSLKEDTGK

Catalytic Activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)

Similarity

Belongs to the class-I aminoacyl-tRNA synthetase family.

Keywords

Aminoacyl-tRNA synthetase   ATP-binding   Complete proteome   Ligase   Nucleotide-binding   Protein biosynthesis   Reference proteome  

Feature

chain  Probable glutamine--tRNA ligase

Uniprot

A0A2A4JS68   A0A3S2NAN0   A0A194QES4   A0A212F4G9   A0A194RHZ0   A0A0K8TME8   + More
A0A0L0BWB5   B3P6N3   B4QUS0   Q9Y105   A0A0A1WJU8   B4PU99   Q16Q55   A0A034WV61   A0A0K8VQS0   A0A336LZF8   B4IJJ7   A0A1Y1LYH9   B4LZ26   A0A023EV58   B4KD69   A0A1W4V8D9   A0A1I8N3T0   A0A067QTT5   W8C525   B3LWJ8   N6TG00   B4NIU8   D6WDE3   A0A1B0CGP3   A0A1W4WMG2   U4U4V7   A0A1L8DRP0   A0A1B0BSN4   A0A0M4F566   A0A1L8DRY3   A0A1I8PEM1   B4JZ15   A0A1J1I248   A0A1A9Y3Z1   U5EU71   A0A3B0KKM0   A0A1A9VVV3   A0A1A9Z3P5   B4GEZ5   Q296L9   A0A1B0FLA7   E2C1V4   A0A0J7L167   E9JCW8   A0A0P5TBQ4   A0A0P6HLW3   A0A0P6G6W0   A0A0N7ZQS6   A0A1B6ID08   A0A026X3L9   A0A158NXU5   A0A1B6GDB6   A0A151I404   B0W0R5   A0A1Q3FA47   F4WLV2   A0A195FWX0   T1DG64   A0A151WIJ5   A0A1A9WRW2   A0A0P5RKW1   E9FZJ3   E0VVD4   A0A151JMB3   E2B161   A0A2A3E8U3   A0A164UIH2   A0A0L7QKJ9   A0A0P6C6V3   A0A087ZR95   A0A1B6C6I6   A0A154PK38   A0A310SJ21   A0A182PPV3   A0A3Q0J8Q5   A0A182YRS7   T1P888   A0A182J8K0   A0A182X1R6   A0A0N8CKP4   Q7Q0M3   A0A182I0V5   A0A182V426   A0A1Q3F9X5   A0A2R7VTW8   Q2NLA5   A0A1B0CZE9   A0A1L8GQ05   A0A0P5VUJ4   A0A1W5AVS9   A7S8N2   U3KF37   A0A3Q1FYN3   A0A2I4BV78  

EC Number

6.1.1.18

Pubmed

26354079    22118469    26369729    26108605    17994087    10731132    + More
12537572    10731138    25830018    17550304    17510324    25348373    28004739    24945155    25315136    24845553    24495485    23537049    18362917    19820115    15632085    20798317    21282665    24508170    21347285    21719571    24330624    21292972    20566863    25244985    12364791    14747013    17210077    27762356    17615350   

EMBL

NWSH01000673    PCG74887.1    RSAL01000144    RVE45973.1    KQ459299    KPJ01966.1    + More
AGBW02010374    OWR48627.1    KQ460205    KPJ16945.1    GDAI01002074    JAI15529.1    JRES01001243    KNC24325.1    CH954182    EDV53703.1    CM000364    EDX14386.1    AE014297    AF145668    GBXI01015155    JAC99136.1    CM000160    EDW98786.1    CH477760    EAT36523.1    GAKP01000852    GAKP01000851    JAC58100.1    GDHF01011100    GDHF01001528    JAI41214.1    JAI50786.1    UFQS01000320    UFQT01000320    SSX02832.1    SSX23200.1    CH480848    EDW51188.1    GEZM01049080    JAV76117.1    CH940650    EDW68129.1    GAPW01000263    JAC13335.1    CH933806    EDW14851.1    KK853024    KDR12338.1    GAMC01002022    JAC04534.1    CH902617    EDV41592.1    APGK01039247    KB740969    ENN76683.1    CH964272    EDW84850.1    KQ971321    EEZ99471.1    AJWK01011503    KB631730    ERL85641.1    GFDF01004948    JAV09136.1    JXJN01019786    CP012526    ALC46632.1    GFDF01004947    JAV09137.1    CH916378    EDV98630.1    CVRI01000038    CRK94415.1    GANO01001619    JAB58252.1    OUUW01000008    SPP84328.1    CH479182    EDW34180.1    CM000070    EAL28438.1    CCAG010010321    GL452008    EFN78066.1    LBMM01001488    KMQ96224.1    GL771866    EFZ09255.1    GDIP01130281    JAL73433.1    GDIQ01017432    JAN77305.1    GDIQ01048159    JAN46578.1    GDIP01221729    JAJ01673.1    GECU01022900    JAS84806.1    KK107013    EZA62905.1    ADTU01003549    GECZ01009476    JAS60293.1    KQ976462    KYM84627.1    DS231818    EDS41367.1    GFDL01010667    JAV24378.1    GL888216    EGI64834.1    KQ981204    KYN44926.1    GALA01000297    JAA94555.1    KQ983089    KYQ47683.1    GDIQ01100989    JAL50737.1    GL732528    EFX87065.1    DS235811    EEB17340.1    KQ978931    KYN27459.1    GL444789    EFN60585.1    KZ288322    PBC28130.1    LRGB01001581    KZS11392.1    KQ414954    KOC59075.1    GDIP01012469    JAM91246.1    GEDC01028389    JAS08909.1    KQ434943    KZC12205.1    KQ762196    OAD56129.1    KA644896    AFP59525.1    GDIP01122295    JAL81419.1    AAAB01008980    EAA13964.3    APCN01005274    GFDL01010660    JAV24385.1    KK854085    PTY10952.1    BC110784    AAI10785.1    AJVK01020711    AJVK01020712    CM004472    OCT85866.1    GDIP01109632    JAL94082.1    DS469598    EDO40014.1    AGTO01010598   

Proteomes

UP000218220    UP000283053    UP000053268    UP000007151    UP000053240    UP000037069    + More
UP000008711    UP000000304    UP000000803    UP000002282    UP000008820    UP000001292    UP000008792    UP000009192    UP000192221    UP000095301    UP000027135    UP000007801    UP000019118    UP000007798    UP000007266    UP000092461    UP000192223    UP000030742    UP000092460    UP000092553    UP000095300    UP000001070    UP000183832    UP000092443    UP000268350    UP000078200    UP000092445    UP000008744    UP000001819    UP000092444    UP000008237    UP000036403    UP000053097    UP000005205    UP000078540    UP000002320    UP000007755    UP000078541    UP000075809    UP000091820    UP000000305    UP000009046    UP000078492    UP000000311    UP000242457    UP000076858    UP000053825    UP000005203    UP000076502    UP000075885    UP000079169    UP000076408    UP000075880    UP000076407    UP000007062    UP000075840    UP000075903    UP000092462    UP000186698    UP000192224    UP000001593    UP000016665    UP000257200    UP000192220   

PRIDE

Q9Y105   

Pfam

PF04558   tRNA_synt_1c_R1        + More
PF04557   tRNA_synt_1c_R2
PF03950   tRNA-synt_1c_C
PF00749   tRNA-synt_1c
PF00849   PseudoU_synth_2

Interpro

IPR020059   Glu/Gln-tRNA-synth_Ib_codon-bd        + More
IPR007639   Gln-tRNA-synth_Ib_RNA-bd_N       
IPR004514   Gln-tRNA-synth       
IPR007638   Gln-tRNA-synth_Ib_RNA-bd_2       
IPR020058   Glu/Gln-tRNA-synth_Ib_cat-dom       
IPR011035   Ribosomal_L25/Gln-tRNA_synth       
IPR001412   aa-tRNA-synth_I_CS       
IPR014729   Rossmann-like_a/b/a_fold       
IPR000924   Glu/Gln-tRNA-synth       
IPR020056   Rbsml_L25/Gln-tRNA_synth_N       
IPR000297   PPIase_PpiC       
IPR020103   PsdUridine_synth_cat_dom_sf       
IPR006145   PsdUridine_synth_RsuA/RluA       

SUPFAM

SSF50715   SSF50715        + More
SSF55120   SSF55120       

Gene 3D

2.40.240.10     3.40.50.620    

CDD

cd02869  PseudoU_synth_RluCD_like

ProteinModelPortal

A0A2A4JS68   A0A3S2NAN0   A0A194QES4   A0A212F4G9   A0A194RHZ0   A0A0K8TME8   + More
A0A0L0BWB5   B3P6N3   B4QUS0   Q9Y105   A0A0A1WJU8   B4PU99   Q16Q55   A0A034WV61   A0A0K8VQS0   A0A336LZF8   B4IJJ7   A0A1Y1LYH9   B4LZ26   A0A023EV58   B4KD69   A0A1W4V8D9   A0A1I8N3T0   A0A067QTT5   W8C525   B3LWJ8   N6TG00   B4NIU8   D6WDE3   A0A1B0CGP3   A0A1W4WMG2   U4U4V7   A0A1L8DRP0   A0A1B0BSN4   A0A0M4F566   A0A1L8DRY3   A0A1I8PEM1   B4JZ15   A0A1J1I248   A0A1A9Y3Z1   U5EU71   A0A3B0KKM0   A0A1A9VVV3   A0A1A9Z3P5   B4GEZ5   Q296L9   A0A1B0FLA7   E2C1V4   A0A0J7L167   E9JCW8   A0A0P5TBQ4   A0A0P6HLW3   A0A0P6G6W0   A0A0N7ZQS6   A0A1B6ID08   A0A026X3L9   A0A158NXU5   A0A1B6GDB6   A0A151I404   B0W0R5   A0A1Q3FA47   F4WLV2   A0A195FWX0   T1DG64   A0A151WIJ5   A0A1A9WRW2   A0A0P5RKW1   E9FZJ3   E0VVD4   A0A151JMB3   E2B161   A0A2A3E8U3   A0A164UIH2   A0A0L7QKJ9   A0A0P6C6V3   A0A087ZR95   A0A1B6C6I6   A0A154PK38   A0A310SJ21   A0A182PPV3   A0A3Q0J8Q5   A0A182YRS7   T1P888   A0A182J8K0   A0A182X1R6   A0A0N8CKP4   Q7Q0M3   A0A182I0V5   A0A182V426   A0A1Q3F9X5   A0A2R7VTW8   Q2NLA5   A0A1B0CZE9   A0A1L8GQ05   A0A0P5VUJ4   A0A1W5AVS9   A7S8N2   U3KF37   A0A3Q1FYN3   A0A2I4BV78  

PDB

4R3Z     E-value=0,     Score=2357

KEGG

101746989    K01886 glutaminyl-tRNA synthetase [EC:6.1.1.18] | (RefSeq) probable glutamine--tRNA ligase

PATHWAY

00970    Aminoacyl-tRNA biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0004819   GO:0006425   GO:0005737   GO:0006412   GO:0004812   GO:0017101   GO:0048813   GO:0005829   GO:0003755   GO:0009982   GO:0003723   GO:0001522   GO:2001234   GO:0004860   GO:0007420   GO:0019901   GO:0032873   GO:0045892   GO:0000166   GO:0006418   GO:0016876   GO:0043039  

Length:

780

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.601269999999999

Exp number, first 60 AAs:

0.02926

Total prob of N-in:

0.00203

outside

1  -  780

 

 

Pi

38.168195

Theta

171.007889

Tajima's D

-1.043255

CLR

165.361315

CSRT

0.134293285335733

Interpretation

Uncertain