Gene

KWMTBOMO07862  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001201

Annotation

muscular_protein_20_[Bombyx_mori]

Location

Bomo_Chr13(-):8751826-8753899      View in EpiBrowser

Full name

Transgelin       + More
Muscle-specific protein 20      
Calponin      

Location in the cell

Cytoplasmic   Reliability : 3.098

CDS

ATGTCTCTGGAACGTCAAGTTCGCGCTAAGATCGCTTCCAAGCGCAACCCTGAGAAGGAGAAGGAAGCCCAAGAGTGGATTGAGGGCGTCCTCGGAGCTAAATTCCCCCCTGGTGAACTATTTGAGGATGTCCTCAAGGACGGCACTGTTCTTTGCCAGCTCATCAACAAGCTGAAGCCTGGCTCTGTCCCCAAGATCAACACCACCGGTGGACAGTTCAAAATGATGGAGAACATCACAAACTTCCAGTCTGCAATCAAAGCATACGGTGTACCCGACATCGATGTGTTCCAAACCGTAGATCTATGGGAGAAAAAAGACATCGCCCAAGTAGTCAGCACACTGTTTGCCCTCGGTCGTGAGACTTACAGACACGCGGAATGGAGCGGCCCCTGCCTCGGACCCAAGCCCGCTGACGAATGCAAACGTGACTTTTCTGATGAAGTCCTGAAGGCCGGGCAAACTGTGATCGGTCTGCAAGCTGGATCTAACAAGGGAGCCACTCAATCCGGACAGAACCTTGGCGCCGGCCGCAAGATCTTGATCGGCAAGTGA

Protein

MSLERQVRAKIASKRNPEKEKEAQEWIEGVLGAKFPPGELFEDVLKDGTVLCQLINKLKPGSVPKINTTGGQFKMMENITNFQSAIKAYGVPDIDVFQTVDLWEKKDIAQVVSTLFALGRETYRHAEWSGPCLGPKPADECKRDFSDEVLKAGQTVIGLQAGSNKGATQSGQNLGAGRKILIGK

Description

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

Similarity

Belongs to the calponin family.

Keywords

Complete proteome   Muscle protein   Reference proteome  

Feature

chain  Muscle-specific protein 20

Uniprot

Q1HPM4   A0A194RLS1   B2DBM1   A0A1E1W5M2   A0A212F4G1   I4DM58   + More
A0A2H1VBJ6   A0A2A4JE78   S4PIM7   A0A3S2TH87   A0A0L7LSX7   Q4PLJ5   D2A180   A0A1Y1LLP1   E0VVT9   A0A088ASZ6   A0A195BX95   A0A158NE93   A0A146MEZ0   A0A310ST38   D3KCZ4   E2A7Y2   A0A3L8DBZ7   A0A1B0EZ23   A0A2A3E5F8   A0A224XYQ6   B4J5B9   B4LLZ5   A0A2J7R368   J3JTP7   N6UTP9   U4UFM7   P14318   A0A170ZG36   A0A1S3DH29   A6YPG4   A0A067RMR7   A0A1W4UP72   A0A1L8E5F5   W8BPQ5   B4QE11   Q293A9   B4GBZ2   K7J2Y6   B4P4J9   A0A069DQ05   A0A1A9V265   A0A1B0AF76   A0A1B0C2A9   A0A336MU40   R4UWC0   A0A0P4VTZ7   R4G571   D3TR28   A0A0A1X9L0   A0A0K8UXE9   A0A3B0JMP9   A0A1A9X4U1   B4KLL7   A0A1A9YMQ3   A2I3Z4   B3NRN3   B4N606   Q174L5   A0A023EII5   K7JCT5   A0A1W4X809   A0A0L0C0X0   C4WUV1   A0A0C9R006   B6SD94   B3MGW5   A0A336MQY0   A0A0M3QUS3   A0A195CAT4   A0A034VUN3   T1PF80   A0A1B6CUU6   A0A151WSP7   A0A182R5D1   A0A182QPI1   A0A0J7NRU0   A0A1L8EG52   A0A1I8Q785   A0A026WVU5   A0A182T139   E9IEL8   A0A0L7RB79   A0A1Q3FLN3   A0A182U829   A0A182KSL8   Q7PV70   A0A2R7WMN1   A0A182Y1R8   T1DNC1   A0A0K8TL73   U5EWN7   A0A182XNC2   A0A182MAK6   A0A182HQ43  

Pubmed

19121390    26354079    18712529    22118469    22651552    23622113    + More
26227816    18362917    19820115    28004739    20566863    21347285    26823975    20798317    30249741    17994087    22516182    23537049    2537318    10731132    12537572    12537569    18207082    24845553    24495485    22936249    15632085    20075255    17550304    26334808    27129103    20353571    25830018    17510324    24945155    26483478    26108605    25348373    25315136    24508170    21282665    20966253    12364791    14747013    17210077    25244985    26369729   

EMBL

BABH01000847    DQ443378    ABF51467.1    KQ460205    KPJ16931.1    AB264705    + More
KQ459299    BAG30780.1    KPJ01979.1    GDQN01008784    JAT82270.1    AGBW02010374    OWR48614.1    AK402376    BAM18998.1    ODYU01001655    SOQ38181.1    NWSH01001911    PCG69703.1    GAIX01005340    JAA87220.1    RSAL01000144    RVE45985.1    JTDY01000155    KOB78552.1    DQ067276    AAY68367.1    KQ971338    EFA01574.1    GEZM01056108    JAV72845.1    DS235814    EEB17495.1    KQ976401    KYM92576.1    ADTU01013175    GDHC01000864    JAQ17765.1    KQ760498    OAD60090.1    GU471216    ADC34222.1    GL437442    EFN70461.1    QOIP01000010    RLU17409.1    AJVK01014993    KZ288361    PBC26993.1    GFTR01003063    JAW13363.1    CH916367    EDW01761.1    CH940648    EDW59915.1    NEVH01007822    PNF35287.1    BT126604    AEE61568.1    APGK01016035    APGK01016038    APGK01016045    KB739734    KB739733    KB739732    ENN82137.1    ENN82142.1    ENN82145.1    KB632168    ERL89371.1    Y00795    AE013599    AY071496    BT024979    GEMB01002240    JAS00940.1    EF638975    ABR27860.1    KK852417    KDR24338.1    GFDF01000151    JAV13933.1    GAMC01003350    JAC03206.1    CM000362    CM002911    EDX06905.1    KMY93459.1    CM000071    EAL24702.1    CH479181    EDW31371.1    CM000158    EDW90638.1    GBGD01003123    JAC85766.1    JXJN01024431    UFQT01002525    UFQT01002536    SSX33629.1    SSX33640.1    KC740737    AGM32561.1    GDKW01000577    JAI56018.1    ACPB03002842    GAHY01000760    JAA76750.1    EZ423880    ADD20156.1    GBXI01006877    JAD07415.1    GDHF01021063    JAI31251.1    OUUW01000001    SPP73901.1    CH933808    EDW08653.1    EF070497    ABM55563.1    CH954179    EDV56185.1    CH964154    EDW79795.1    CH477409    EAT41488.1    JXUM01095164    GAPW01004843    KQ564176    JAC08755.1    KXJ72621.1    AAZX01014685    JRES01001157    KNC25114.1    ABLF02031123    AK341232    BAH71671.1    GBYB01009419    JAG79186.1    EU808012    ACJ02089.1    CH902619    EDV37883.1    UFQT01002210    SSX32934.1    CP012524    ALC41133.1    KQ978023    KYM97922.1    GAKP01013392    JAC45560.1    KA647401    AFP62030.1    GEDC01020038    JAS17260.1    KQ982769    KYQ50858.1    AXCN02001041    LBMM01002203    KMQ95150.1    GFDG01001220    JAV17579.1    KK107079    EZA60165.1    GL762647    EFZ20996.1    KQ414618    KOC67996.1    GFDL01006588    JAV28457.1    AAAB01008986    EAA00381.4    KK855008    PTY20260.1    GAMD01003015    JAA98575.1    GDAI01002692    JAI14911.1    GANO01001330    JAB58541.1    AXCM01005696    APCN01003291   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000218220    UP000283053    + More
UP000037510    UP000007266    UP000009046    UP000005203    UP000078540    UP000005205    UP000000311    UP000279307    UP000092462    UP000242457    UP000001070    UP000008792    UP000235965    UP000019118    UP000030742    UP000000803    UP000079169    UP000027135    UP000192221    UP000000304    UP000001819    UP000008744    UP000002358    UP000002282    UP000078200    UP000092445    UP000092460    UP000015103    UP000268350    UP000091820    UP000009192    UP000092443    UP000008711    UP000007798    UP000008820    UP000069940    UP000249989    UP000192223    UP000037069    UP000007819    UP000007801    UP000092553    UP000078542    UP000095301    UP000075809    UP000075900    UP000075886    UP000036403    UP000095300    UP000053097    UP000075901    UP000053825    UP000075902    UP000075882    UP000007062    UP000076408    UP000076407    UP000075883    UP000075840   

PRIDE

Q1HPM4    P14318   

Pfam

PF00402   Calponin        + More
PF00307   CH
PF00412   LIM

Interpro

IPR003096   SM22_calponin        + More
IPR001715   CH-domain       
IPR036872   CH_dom_sf       
IPR000557   Calponin_repeat       
IPR001781   Znf_LIM       
IPR001997   Calponin/LIMCH1       

SUPFAM

SSF47576   SSF47576       

Gene 3D

1.10.418.10    

CDD

cd00014  CH

ProteinModelPortal

Q1HPM4   A0A194RLS1   B2DBM1   A0A1E1W5M2   A0A212F4G1   I4DM58   + More
A0A2H1VBJ6   A0A2A4JE78   S4PIM7   A0A3S2TH87   A0A0L7LSX7   Q4PLJ5   D2A180   A0A1Y1LLP1   E0VVT9   A0A088ASZ6   A0A195BX95   A0A158NE93   A0A146MEZ0   A0A310ST38   D3KCZ4   E2A7Y2   A0A3L8DBZ7   A0A1B0EZ23   A0A2A3E5F8   A0A224XYQ6   B4J5B9   B4LLZ5   A0A2J7R368   J3JTP7   N6UTP9   U4UFM7   P14318   A0A170ZG36   A0A1S3DH29   A6YPG4   A0A067RMR7   A0A1W4UP72   A0A1L8E5F5   W8BPQ5   B4QE11   Q293A9   B4GBZ2   K7J2Y6   B4P4J9   A0A069DQ05   A0A1A9V265   A0A1B0AF76   A0A1B0C2A9   A0A336MU40   R4UWC0   A0A0P4VTZ7   R4G571   D3TR28   A0A0A1X9L0   A0A0K8UXE9   A0A3B0JMP9   A0A1A9X4U1   B4KLL7   A0A1A9YMQ3   A2I3Z4   B3NRN3   B4N606   Q174L5   A0A023EII5   K7JCT5   A0A1W4X809   A0A0L0C0X0   C4WUV1   A0A0C9R006   B6SD94   B3MGW5   A0A336MQY0   A0A0M3QUS3   A0A195CAT4   A0A034VUN3   T1PF80   A0A1B6CUU6   A0A151WSP7   A0A182R5D1   A0A182QPI1   A0A0J7NRU0   A0A1L8EG52   A0A1I8Q785   A0A026WVU5   A0A182T139   E9IEL8   A0A0L7RB79   A0A1Q3FLN3   A0A182U829   A0A182KSL8   Q7PV70   A0A2R7WMN1   A0A182Y1R8   T1DNC1   A0A0K8TL73   U5EWN7   A0A182XNC2   A0A182MAK6   A0A182HQ43  

PDB

1WYN     E-value=2.16876e-21,     Score=248

KEGG

733016    K20526 transgelin | (RefSeq) muscular protein 20

GO

GO:0046872   GO:1901739   GO:0007520   GO:0003779   GO:0005737   GO:0005516   GO:0031032   GO:0005515   GO:0016192   GO:0051082   GO:0005506   GO:0030145   GO:0050906   GO:0016818   GO:0003707   GO:0051537  

Length:

184

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00022

Exp number, first 60 AAs:

0

Total prob of N-in:

0.29186

outside

1  -  184

 

 

Pi

176.090846

Theta

212.171254

Tajima's D

-0.474362

CLR

0.430126

CSRT

0.248987550622469

Interpretation

Uncertain