Gene

KWMTBOMO07848

Pre Gene Modal

BGIBMGA001208

Annotation

PREDICTED:_anaphase-promoting_complex_subunit_4_[Papilio_xuthus]

Location

Bomo_Chr13(-):8258083-8265252      View in EpiBrowser

Full name

Anaphase-promoting complex subunit 4      

Alternative Name

Cyclosome subunit 4

Location in the cell

Cytoplasmic   Reliability : 1.867 Nuclear   Reliability : 1.617

CDS

ATGCATTGTGGTATGAGGCAAGTTGGAGAGAGGCATGTGCCCTATCAAGTTGATCTTATGGTCTGGAGTAACCGTCTGGATTTGCTAGCATTAAGTAATAATAAAGGTGAAGTCCAAATACATAGATTGCATTGGCAAAAAGTATGGAGCTTACCACCTCCAAAAGAAAATGGCTGTGTACAAGCGATGGCTTGGAGACCTGATGGAAAGGCTCTAGCTATTGGATACAATTTAGGAATTATTTATACAGTTAGTGTGGAAGACAAGGGTATAATTGATAAGTATGAATTGGAACTAGAAGTCACAGATGAACTTGATACTGCTAAGTATAGCGGCATTTCTTGTATTGTATGGGCGATACGAACTGACATCTTGCAAAGTGCCACTGAATATAATTTATATGATGATGCCTCAATATTTTTACAAAAAGTTCCAATGTCGAGTGGATACAAAAACAGTCATGAAGACAACAAAGATTGCAAGTACATACAGAATCCCACACAACTGAACATGTTAATTGTCGGATACGGAACAGGCAACATTTACCTGAACATGTATGGCAGGTATCCGTATGGAACTATTCAACTGGCAGAAGTGGCCAAAGATGATTTTGGAGAGTACAAAGTGTTAGACGTTAATATGTCAGATGACTTCAGTGTCATGCAAGTTCTTTATGTGGATAGATTGACAAATAATGTTTTTTTGGCTATTGTTAACACTGGCGTATTATCTGCATACGCCGATGAAATAAACACGGTAGCACATAAACATGGACAAATTGTTCAGCTGATGACTCAACTTGATCAAACGATGATTTCAATTACTGAAGCATGGGAACATATATTGCTTGAAATGGATACTAAAATGGCATATTACGCTTCATCTGTGCACGAGGGAGGGGTTTCAGCTGATCTATTAGAACTACTCATGTTAGGTACTCCATCAGTGGATTTACAAGTTTACCTTTTGGAAAAATTGACAACTAATGACTTGAAAAAATTTGGAAATTCTGTTGAATTAAGTTACTCGACCATACAGAAGCTGGTACTGAAACAACTCAATATTGTTGGCCAAAGTTTAGTTTATTATTTAGCCGAACTCAGAGGACTCACAAGGATAGAAGACAGATACAAGATTCTAGGTTTAGAAGAAAGCAGTGTTACAGAAGCGATAAAAGCATGTTGTGCATTTTTAAACAAATGTCTGGAATTACAACAGGTTATTGATGTATCGATGCGGAACTATAAAGCTTTCTTCAGGTGGCTTTTTGTAGTAATCGTTAGACAACTGGATGAACAAACACCAAGTGAAATTGTGAAAATAAATCAACAGGAATTGAGCCACATAGCGGAGTTTCTCTACAATTTTGACAATGTAAAAGTAGACAGTTCAGACAAACCACCTGATAAATTGATCAAATTTAATTTAGAAAGATTAGGGCAATATTTGCAAAATCAAGAACTGACAATTTTGCCAGAAGATGAAGACAACACATGGCATAAATTTCTTCAAGACAATGCTTGCTTCCTTAAAGACAATGATACATTTTTCTCCATGAAAGACTTCAAAAAATATTCATTAGTTCAACAGCAAGCACATCTTATAGAGACAGTCACTAAAGTTTTTGATGTCGTTCATAAAGATACAGGAAAATATTTTTCTGTATTATGTAATATTAGATGCCACGAAGATCAACTGAATAAAAACCTGCACAATAGTTTGAGAGTTTCACAAGTCTTTGATGACACAAATAAACGATTGATGTCGGCCTTTTTGGATATATCAAATGGAAAAGAAGGAATTTATTTTTTGGCTGTCAATATAAAGGAGAGATCTTGTAATATTGCAGTTATGAAATGCTACTTTTCTTCTTATTTAGTTCAAAATGGCACTGATGATCAACAAAACGAACCTACAAATTTATTAGATTTACAATTCTATTCCCCAGAATATTTGTCAGTTATTACAACACATCCTGAAAATGAGGAAAATACAATATTTATTCAGGTACCAGTAAAACATCTCCTAGAAAATTCTACTGAACTCAATATTAACACAAAATCTTGTATTTTTACTGACAGAAGTGTAAAGAAGGATATTGCGCCTTTATTAGAACAGAATGTTTATAAAGTGCTTGAGAAAATGGACGGTTCAAGATTAGCAGTTTCTGGAGGTCGTAAAGTTGCTGTTATCCTTTCAAAAAGTTCTCGAAAAGTTAGAGTATTTGAAATGGAAGTTGATGGTGATGATGATGAAGACGATACTCTCGATACAACACCACAATCTATTGGAAAATTTCAAAACACACCTGATAAAAGTAATACTACCAATGAAGACAATATTTTTTAA

Protein

MHCGMRQVGERHVPYQVDLMVWSNRLDLLALSNNKGEVQIHRLHWQKVWSLPPPKENGCVQAMAWRPDGKALAIGYNLGIIYTVSVEDKGIIDKYELELEVTDELDTAKYSGISCIVWAIRTDILQSATEYNLYDDASIFLQKVPMSSGYKNSHEDNKDCKYIQNPTQLNMLIVGYGTGNIYLNMYGRYPYGTIQLAEVAKDDFGEYKVLDVNMSDDFSVMQVLYVDRLTNNVFLAIVNTGVLSAYADEINTVAHKHGQIVQLMTQLDQTMISITEAWEHILLEMDTKMAYYASSVHEGGVSADLLELLMLGTPSVDLQVYLLEKLTTNDLKKFGNSVELSYSTIQKLVLKQLNIVGQSLVYYLAELRGLTRIEDRYKILGLEESSVTEAIKACCAFLNKCLELQQVIDVSMRNYKAFFRWLFVVIVRQLDEQTPSEIVKINQQELSHIAEFLYNFDNVKVDSSDKPPDKLIKFNLERLGQYLQNQELTILPEDEDNTWHKFLQDNACFLKDNDTFFSMKDFKKYSLVQQQAHLIETVTKVFDVVHKDTGKYFSVLCNIRCHEDQLNKNLHNSLRVSQVFDDTNKRLMSAFLDISNGKEGIYFLAVNIKERSCNIAVMKCYFSSYLVQNGTDDQQNEPTNLLDLQFYSPEYLSVITTHPENEENTIFIQVPVKHLLENSTELNINTKSCIFTDRSVKKDIAPLLEQNVYKVLEKMDGSRLAVSGGRKVAVILSKSSRKVRVFEMEVDGDDDEDDTLDTTPQSIGKFQNTPDKSNTTNEDNIF

Description

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

Similarity

Belongs to the APC4 family.

Uniprot

H9IVC8   A0A2A4JUJ5   A0A1E1W2B8   A0A2H1VIF7   A0A3S2NQA1   A0A194RLQ6   + More
A0A212ELY5   A0A0L7KTE4   S4PKX4   A0A2P8XZ14   A0A067QTS3   A0A2J7QCE7   A0A1B6CIQ6   E0VSJ0   D6X523   A0A1W4X6Z9   A0A2R7WK79   T1HVG5   A0A2R5LB43   A0A1Y1K6V9   A0A0P4VVD1   A0A0V0G938   A0A023EYH7   A0A224XKL0   A0A146L2N3   A0A069DX40   A0A131YNM9   A0A293LQR7   A0A224YT21   L7M4W2   A0A2A3EEF1   A0A1E1XDI9   A0A088AB10   B0WQG6   Q17Q34   T1IJR4   A0A1Q3EVW2   A0A2L2YNB4   A0A0C9QP78   A0A3L8E369   A0A182G704   A0A151ISP8   E2AWS7   A0A182HD98   A0A158N9R1   A0A147BHC2   A0A131Y0Y8   A0A1S3IY64   K7J2G7   L7LU08   E2BQ97   A0A0A9W336   A0A182RCV6   A0A336MKM9   A0A182PA17   A0A182ME35   W5JCA0   A0A2T7PLB7   A0A1B0GH85   A0A182K3T0   A0A182FR78   A0A182V2P4   A0A182VQ87   A0A182JMB5   A0A182TRA9   A0A182XID8   A0A182T898   A0A084VAG8   A0A182LFH3   A0A182Y7A5   Q7QBX1   A0A182HTC2   A0A336MQA3   J9K589   A0A2H8U2S7   K1QRG2   A0A2C9KKK8   B7PFT0   A0A182N4M3   Q6NU36   A0A1L8HTH1   G3PM58   G3PM55   F6R9H8   H0ZGG6   H9GKA5   A0A1V4JFK0   A0A3P8XHW8   W4YZB5   B5DEU5   B4F754   A0A091RHL3   A0A0P5V737   A0A0P5NKB0   A0A3S3NXG4  

Pubmed

19121390    26354079    22118469    26227816    23622113    29403074    + More
24845553    20566863    18362917    19820115    28004739    25474469    26823975    26334808    26830274    28797301    25576852    28503490    17510324    26561354    30249741    26483478    20798317    21347285    29652888    20075255    25401762    20920257    23761445    24438588    20966253    25244985    12364791    14747013    17210077    22992520    15562597    26343760    27762356    17495919    20360741    21881562    25069045   

EMBL

BABH01000895    NWSH01000642    PCG75080.1    GDQN01009960    JAT81094.1    ODYU01002495    + More
SOQ40044.1    RSAL01000152    RVE45707.1    KQ460205    KPJ16916.1    AGBW02013971    OWR42488.1    JTDY01006094    KOB66299.1    GAIX01004305    JAA88255.1    PYGN01001141    PSN37237.1    KK852962    KDR13200.1    NEVH01016289    PNF26257.1    GEDC01029590    GEDC01023960    JAS07708.1    JAS13338.1    DS235751    EEB16346.1    KQ971382    EEZ97189.1    KK854925    PTY19721.1    ACPB03012952    GGLE01002559    MBY06685.1    GEZM01090702    JAV57192.1    GDRN01093292    JAI59911.1    GECL01001715    JAP04409.1    GBBI01004332    JAC14380.1    GFTR01007855    JAW08571.1    GDHC01017172    JAQ01457.1    GBGD01000622    JAC88267.1    GEDV01008405    JAP80152.1    GFWV01005666    MAA30396.1    GFPF01005988    MAA17134.1    GACK01006851    JAA58183.1    KZ288267    PBC30090.1    GFAC01001929    JAT97259.1    DS232039    EDS32837.1    CH477187    EAT48882.1    JH430339    GFDL01015602    JAV19443.1    IAAA01030524    LAA09612.1    GBYB01005369    GBYB01005370    JAG75136.1    JAG75137.1    QOIP01000001    RLU27127.1    JXUM01149330    KQ570750    KXJ68308.1    KQ981064    KYN09859.1    GL443424    EFN62113.1    JXUM01129324    KQ567431    KXJ69427.1    ADTU01009799    GEGO01005552    JAR89852.1    GEFM01004245    JAP71551.1    GACK01009734    JAA55300.1    GL449698    EFN82151.1    GBHO01041392    GBHO01041390    GBRD01003032    JAG02212.1    JAG02214.1    JAG62789.1    UFQT01001536    SSX30962.1    AXCM01001115    ADMH02001587    ETN61952.1    PZQS01000003    PVD34194.1    AJWK01004047    ATLV01003731    KE524159    KFB34962.1    AAAB01008859    EAA07454.4    APCN01000438    SSX30963.1    ABLF02037625    GFXV01008063    MBW19868.1    JH817380    EKC36338.1    ABJB010486839    ABJB010599450    ABJB010636447    ABJB010777657    DS704057    EEC05452.1    BC068765    AAH68765.1    CM004466    OCT99403.1    ABQF01015373    AAWZ02025654    LSYS01007721    OPJ70981.1    AAGJ04149890    BC168806    AAI68806.1    BC168138    AAI68138.1    KK818965    KFQ39328.1    GDIQ01136618    GDIP01103272    LRGB01001348    JAL15108.1    JAM00443.1    KZS12987.1    GDIQ01141076    JAL10650.1    NCKU01001876    RWS11030.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053240    UP000007151    UP000037510    + More
UP000245037    UP000027135    UP000235965    UP000009046    UP000007266    UP000192223    UP000015103    UP000242457    UP000005203    UP000002320    UP000008820    UP000279307    UP000069940    UP000249989    UP000078492    UP000000311    UP000005205    UP000085678    UP000002358    UP000008237    UP000075900    UP000075885    UP000075883    UP000000673    UP000245119    UP000092461    UP000075881    UP000069272    UP000075903    UP000075920    UP000075880    UP000075902    UP000076407    UP000075901    UP000030765    UP000075882    UP000076408    UP000007062    UP000075840    UP000007819    UP000005408    UP000076420    UP000001555    UP000075884    UP000186698    UP000007635    UP000002280    UP000007754    UP000001646    UP000190648    UP000265140    UP000007110    UP000076858    UP000285301   

PRIDE

H9IVC8    L7M4W2    L7LU08   

Pfam

PF12894   ANAPC4_WD40        + More
PF12896   ANAPC4

Interpro

IPR024977   Apc4_WD40_dom        + More
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR024789   APC4       
IPR024790   APC4_long_dom       
IPR036322   WD40_repeat_dom_sf       
IPR011044   Quino_amine_DH_bsu       
IPR011047   Quinoprotein_ADH-like_supfam       
IPR017169   APC4_metazoa       

SUPFAM

SSF50978   SSF50978        + More
SSF50969   SSF50969       
SSF50998   SSF50998       

Gene 3D

2.130.10.10    

ProteinModelPortal

H9IVC8   A0A2A4JUJ5   A0A1E1W2B8   A0A2H1VIF7   A0A3S2NQA1   A0A194RLQ6   + More
A0A212ELY5   A0A0L7KTE4   S4PKX4   A0A2P8XZ14   A0A067QTS3   A0A2J7QCE7   A0A1B6CIQ6   E0VSJ0   D6X523   A0A1W4X6Z9   A0A2R7WK79   T1HVG5   A0A2R5LB43   A0A1Y1K6V9   A0A0P4VVD1   A0A0V0G938   A0A023EYH7   A0A224XKL0   A0A146L2N3   A0A069DX40   A0A131YNM9   A0A293LQR7   A0A224YT21   L7M4W2   A0A2A3EEF1   A0A1E1XDI9   A0A088AB10   B0WQG6   Q17Q34   T1IJR4   A0A1Q3EVW2   A0A2L2YNB4   A0A0C9QP78   A0A3L8E369   A0A182G704   A0A151ISP8   E2AWS7   A0A182HD98   A0A158N9R1   A0A147BHC2   A0A131Y0Y8   A0A1S3IY64   K7J2G7   L7LU08   E2BQ97   A0A0A9W336   A0A182RCV6   A0A336MKM9   A0A182PA17   A0A182ME35   W5JCA0   A0A2T7PLB7   A0A1B0GH85   A0A182K3T0   A0A182FR78   A0A182V2P4   A0A182VQ87   A0A182JMB5   A0A182TRA9   A0A182XID8   A0A182T898   A0A084VAG8   A0A182LFH3   A0A182Y7A5   Q7QBX1   A0A182HTC2   A0A336MQA3   J9K589   A0A2H8U2S7   K1QRG2   A0A2C9KKK8   B7PFT0   A0A182N4M3   Q6NU36   A0A1L8HTH1   G3PM58   G3PM55   F6R9H8   H0ZGG6   H9GKA5   A0A1V4JFK0   A0A3P8XHW8   W4YZB5   B5DEU5   B4F754   A0A091RHL3   A0A0P5V737   A0A0P5NKB0   A0A3S3NXG4  

PDB

5BPT     E-value=5.34505e-82,     Score=778

KEGG

101742453    K03351 anaphase-promoting complex subunit 4 | (RefSeq) anaphase-promoting complex subunit 4

PATHWAY

04120    Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)

GO

GO:0005680   GO:0030071   GO:0031145   GO:0070979   GO:0051301   GO:0007049   GO:0045842   GO:0034399   GO:0016021   GO:0019903   GO:0005515   GO:0006779   GO:0043565   GO:0005506   GO:0030145   GO:0050906   GO:0016818   GO:0003707   GO:0051537  

PANTHER

PTHR13260  

Length:

782

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.426600000000001

Exp number, first 60 AAs:

0.00019

Total prob of N-in:

0.02094

outside

1  -  782

 

 

Pi

247.934257

Theta

197.257798

Tajima's D

0.83731

CLR

0.187706

CSRT

0.608219589020549

Interpretation

Uncertain