Gene

KWMTBOMO07830

Pre Gene Modal

BGIBMGA000932

Annotation

PREDICTED:_serine/threonine-protein_phosphatase_rdgC_[Bombyx_mori]

Location

Bomo_Chr13(+):7605181-7640132      View in EpiBrowser

Full name

Serine/threonine-protein phosphatase       + More
Serine/threonine-protein phosphatase with EF-hands      
Serine/threonine-protein phosphatase rdgC      

Alternative Name

Retinal degeneration C protein

Location in the cell

Nuclear   Reliability : 2.096

CDS

ATGTTAGCCGCAGCCATTCCTAAATCCCGCGAAAAAGTGCCAAGATGCAATCGAAAGCGAAGAGATAAAAGCCACAGAGTAAGGGCCAAGAGTCCCACGATGTTTTCTTTGGCTGAGGGTTGTGGGTGCGTTAGTTTTCGTGGCGGTCGACGTACTCGCTCCCAAGGAGATGATTCTTCATCATGTCGGAGCTCAGAAATAGAACAAGAGGTTCCCCAAAGATCGGGTAAAAGACTACTCAATGGCGAATATACCATGAAAGCTTTGGTACCCTTCTTGAAATTTTGGAGAAGAGACGATGTTAGTATGACTAAAGCTGAAAGAACTATGAAAGCCGCCATTTTAATTCAGCAGTGGTACAGGCGTTATTTAGCGCGAATGGAAGTGAGAAGGCGTTATACCTGGACCATATTTCAGAACATTGAATATGCGGGCGAACATGATCAAGTGAAGCTGTATAATTTTTTCAACGCACTGCTCAGCCATATGATGGATACGAATGGGCGGCCCTCCTCCGAGCGTACCTCGAGAACAGCTTCCGTCTTGGAACAAGTTTTTTCCGAAGAGTCTGACGAAGGAGGGGGCGTCGATGAGACCGCTCCCCCGAAGCCTTCACGTGGCCCCGACGTTGAATTCCCGCTACAAAGAAAGGATATCGACCTATTGATTGAGGCATTCAGAAAGAAAAAGCATCGTTTACATCCAAAGCACGTAGCGCAGATACTGAAAGAGGCCACACAAGTATTGAAAAGGTTACCCAATATCAATGTGGCTACCACATCTATATCTAGCCAGATCACTGTTTGCGGAGATCTCCATGGAAAACTAGACGATCTACTCGTCATATTTCACAAGAATGGGCTGCCATCTCCAGAAAATCCGTATATATTTAACGGAGACTTTGTGGACAGAGGCAAGAAGGGTCTAGAAGTGTTTCTTCTGCTGTTAGCGTGCATGCTCGCTTTTCCCGGTGGTGTTTTCTTGAATCGCGGGAATCACGAAGATCTCATTATGAATTCGAGGTACGGCTTCATCAAAGAAGTTCACATGAAGTACAGGCACAATGCTGAGCGTCTTTTGAAACTGATTGAGTGCGTGTATCGGTGGCTTCCACTCGGGACCATCATAAATAATCGAGTTTTCGTTGTCCACGGAGGCATCTCGGATACTACAGACCTAGATATGATTCGGAGCCTTGAAAGGGATAAGTACGTGTCGCTTCTGCGGCCGCCGGTGATCGAGGGCTCAACGGCCGCGGAGTCGATAGATAAGGTGGAGTGGAAGCAGGTGTTTGATATACTGTGGTCGGATCCACAATGCATCGGAGGATGTGTGGCAAATGCGCTTCGAGGAGCAGGAACCTACTTCGGCCCTGATGTAACAGCGTCGTTCCTCCAGAAGAATAAGCTGAGCTTCATAATTAGAAGTCACGAGTGCAAGCCCGGTGGATACGAAATCATGCATGGCGGTAATGTAATTACAATTTTCTCGGCGTCGAACTATTACGAGTTGGGTTCCAACAAGGGCGCTTACCTGAAACTATGCGGGAACTCGTTGGAGCGCCAGTTCGTGCAATACACGGCGGCCGTGTCTCGCACGCGGCGTCTCACCTTCAGGCAGCGGGTTGGCCTTGTCGAATCGTCCGCCATGAGGGAGCTACACAATCAGATTATGATGGCCAGGAGATCTCTGGAAGCTACTTTCCGTAGCTTGGACTCGGAGCAAAGTGGTTTCATATCTATAAGCGATTGGTGTCAAGCCATGGAGGAGACAACACACCTCGGTCTCCCGTGGAGGATGCTTAAAGACAAGCTTGTTCGCACAGATCCCGAGACACGCAAAGTACGTTACATGGATACATTCGAACTCAACACCAATAGGAACGGACGAAAATCTGACACGCTGACAGTCGTCGAGACTTTGTATAAAAATCAAAGAAGCTTGGAGGCGATCTTCAAGATATTGGATAAAGATAATTCTGGTTACATAACGTTGGAAGAATTTTCCGAGGCTTGCCAGCTGATCGGCAAGTACATGCCGAATCCGATGACGCAGGAGCAGCTCGTCGACATCTGTCGGCTCATGGACATCAACAAGGACGGCCTGGTTGATCTCAACGAGTTCCTCGAGAGTTTCCGTCTCGCCGAAAAGAGTTTACACGAGCAGGAAAGGATGTACGAAGACATGCAGGCTACCTGA

Protein

MLAAAIPKSREKVPRCNRKRRDKSHRVRAKSPTMFSLAEGCGCVSFRGGRRTRSQGDDSSSCRSSEIEQEVPQRSGKRLLNGEYTMKALVPFLKFWRRDDVSMTKAERTMKAAILIQQWYRRYLARMEVRRRYTWTIFQNIEYAGEHDQVKLYNFFNALLSHMMDTNGRPSSERTSRTASVLEQVFSEESDEGGGVDETAPPKPSRGPDVEFPLQRKDIDLLIEAFRKKKHRLHPKHVAQILKEATQVLKRLPNINVATTSISSQITVCGDLHGKLDDLLVIFHKNGLPSPENPYIFNGDFVDRGKKGLEVFLLLLACMLAFPGGVFLNRGNHEDLIMNSRYGFIKEVHMKYRHNAERLLKLIECVYRWLPLGTIINNRVFVVHGGISDTTDLDMIRSLERDKYVSLLRPPVIEGSTAAESIDKVEWKQVFDILWSDPQCIGGCVANALRGAGTYFGPDVTASFLQKNKLSFIIRSHECKPGGYEIMHGGNVITIFSASNYYELGSNKGAYLKLCGNSLERQFVQYTAAVSRTRRLTFRQRVGLVESSAMRELHNQIMMARRSLEATFRSLDSEQSGFISISDWCQAMEETTHLGLPWRMLKDKLVRTDPETRKVRYMDTFELNTNRNGRKSDTLTVVETLYKNQRSLEAIFKILDKDNSGYITLEEFSEACQLIGKYMPNPMTQEQLVDICRLMDINKDGLVDLNEFLESFRLAEKSLHEQERMYEDMQAT

Description

Phosphatase required to prevent light-induced retinal degeneration.

Catalytic Activity

H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate
H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate

Cofactor

Mn(2+)

Similarity

Belongs to the PPP phosphatase family.

Keywords

Calcium   Complete proteome   Hydrolase   Magnesium   Manganese   Metal-binding   Protein phosphatase   Reference proteome   Repeat   Sensory transduction   Vision  

Feature

chain  Serine/threonine-protein phosphatase rdgC

Uniprot

A0A194RLP1   H9IUK2   A0A194PJL2   A0A212EZK5   A0A1W4WIT1   A0A1S4F4H5   + More
D2A162   W5JP23   Q17FS3   A0A084WI84   A0A182WR55   A0A182HNP8   A0A182WF17   A0A182RFE2   A0A182NPL6   A0A182FTV4   A0A182PU84   Q7Q2Z9   A0A336KR11   A0A182G6D2   A0A182IJK1   A0A1B6DP80   A0A1B6C198   A0A182V902   A0A0A9XJD6   A0A182MN75   A0A0L0BQ75   A0A0T6AY67   A0A1I8QDX9   E0VT76   B0W8E1   A0A182K8J4   A0A1B0G902   A0A336KZ48   U4US14   A0A1A9WRH1   W8ANN1   A0A1A9VSD6   A0A1A9Z5T7   A0A1B0G8C3   A0A1A9Z4V7   A0A1A9UQS4   A0A0Q5U6J1   A0A1B0B3L8   B4PFC5   A0A0J9RZW2   A0A1B0G581   A0A1W4VUR9   A0A0P8XTK4   A0A3B0K9C5   A0A1A9Z2Z5   A0A0Q5UKB6   A0A0R1E263   B3NE58   A0A0J9RYJ5   A0A0R1E3V8   B4IA68   A0A0J9UPV3   B4MKU9   P40421   A0A0P8XTZ4   A0A0R3P3C9   B3M4R3   A0A3B0KHY3   A0A0Q9WVD8   A0A0R3P3E4   A0A0R3P3H1   A0A0R3P7M8   B5DPA9   A0A1J1IGC9   A0A0Q9XDH4   B4IYR3   B4LG02   A0A0Q9XQA2   B4KV71   A0A0M4EZY5   A0A1A9Y029   B4GR08   A0A2T7PP07   A0A224Z6H9   A0A131YUK5   A0A369SL60   A0A044UXV0   A0A090LKG0   A7RNB7   A0A0N5BXR6   A0A0K0EJQ2   A0A2B4SS40   A0A1S3HU17   A0A0K0F6X9   A0A1I7VS43  

EC Number

3.1.3.16

Pubmed

26354079    19121390    22118469    18362917    19820115    20920257    + More
23761445    17510324    24438588    12364791    26483478    25401762    26823975    26108605    20566863    23537049    24495485    17994087    17550304    22936249    1316807    10731132    12537572    15632085    18057021    23185243    28797301    26830274    30042472    17615350    25217238   

EMBL

KQ460205    KPJ16901.1    BABH01000935    KQ459606    KPI91275.1    AGBW02011268    + More
OWR46920.1    KQ971338    EFA01582.2    ADMH02000929    ETN64645.1    CH477268    EAT45428.1    ATLV01023923    KE525347    KFB49928.1    AAAB01008966    EAA12933.4    UFQS01000791    UFQT01000791    SSX06909.1    SSX27253.1    JXUM01007767    JXUM01007768    JXUM01007769    JXUM01007770    JXUM01007771    JXUM01007772    KQ560247    KXJ83583.1    GEDC01009827    JAS27471.1    GEDC01030006    JAS07292.1    GBHO01023525    GBHO01023524    GDHC01015922    JAG20079.1    JAG20080.1    JAQ02707.1    AXCM01005116    JRES01001542    KNC22133.1    LJIG01022522    KRT80131.1    DS235760    EEB16582.1    DS231858    EDS38870.1    CCAG010002954    CCAG010002955    CCAG010002956    UFQS01001279    UFQT01001279    SSX10107.1    SSX29829.1    KB632337    ERL92855.1    GAMC01016156    GAMC01016155    JAB90400.1    CCAG010000237    CH954178    KQS44297.1    JXJN01007898    JXJN01007899    CM000159    EDW95211.1    CM002912    KMZ00725.1    CCAG010004851    CH902618    KPU78056.1    OUUW01000009    SPP84720.1    KQS44298.1    KRK02291.1    EDV52482.1    KMZ00727.1    KRK02292.1    CH480826    EDW44181.1    KMZ00726.1    CH963847    EDW72874.2    M89628    AE014296    BT015959    KPU78057.1    CH379069    KRT07671.1    EDV39462.1    SPP84721.1    CH940647    KRF84894.1    KRT07672.1    KRT07673.1    KRT07669.1    EDY73443.1    CVRI01000047    CRK98102.1    CH933809    KRG06630.1    CH916366    EDV96600.1    EDW70401.1    KRG06631.1    EDW19411.1    CP012525    ALC44362.1    CH479188    EDW40193.1    PZQS01000003    PVD35141.1    GFPF01011705    MAA22851.1    GEDV01005900    JAP82657.1    NOWV01000006    RDD46763.1    CMVM020000240    LN609529    CEF68045.1    DS469522    EDO47034.1    LSMT01000037    PFX31297.1    JH712149    EJD75329.1   

Proteomes

UP000053240    UP000005204    UP000053268    UP000007151    UP000192223    UP000007266    + More
UP000000673    UP000008820    UP000030765    UP000076407    UP000075920    UP000075900    UP000075884    UP000069272    UP000075885    UP000007062    UP000069940    UP000249989    UP000075880    UP000075903    UP000075883    UP000037069    UP000095300    UP000009046    UP000002320    UP000075881    UP000092444    UP000030742    UP000091820    UP000078200    UP000092445    UP000008711    UP000092460    UP000002282    UP000192221    UP000007801    UP000268350    UP000001292    UP000007798    UP000000803    UP000001819    UP000008792    UP000183832    UP000009192    UP000001070    UP000092553    UP000092443    UP000008744    UP000245119    UP000253843    UP000024404    UP000035682    UP000001593    UP000046392    UP000035681    UP000225706    UP000085678    UP000035680    UP000095285   

PRIDE

H9IUK2    P40421   

Pfam

PF13499   EF-hand_7        + More
PF13202   EF-hand_5
PF00612   IQ
PF00149   Metallophos
PF08321   PPP5
PF13833   EF-hand_8

Interpro

IPR029052   Metallo-depent_PP-like        + More
IPR012008   Ser/Thr-Pase_EF-hand_contain       
IPR002048   EF_hand_dom       
IPR011992   EF-hand-dom_pair       
IPR006186   Ser/Thr-sp_prot-phosphatase       
IPR018247   EF_Hand_1_Ca_BS       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR000048   IQ_motif_EF-hand-BS       
IPR013235   PPP_dom       
IPR041767   MPP_RdgC       

SUPFAM

SSF47473   SSF47473       

Gene 3D

3.60.21.10    

CDD

cd00051  EFh
cd07420  MPP_RdgC

ProteinModelPortal

A0A194RLP1   H9IUK2   A0A194PJL2   A0A212EZK5   A0A1W4WIT1   A0A1S4F4H5   + More
D2A162   W5JP23   Q17FS3   A0A084WI84   A0A182WR55   A0A182HNP8   A0A182WF17   A0A182RFE2   A0A182NPL6   A0A182FTV4   A0A182PU84   Q7Q2Z9   A0A336KR11   A0A182G6D2   A0A182IJK1   A0A1B6DP80   A0A1B6C198   A0A182V902   A0A0A9XJD6   A0A182MN75   A0A0L0BQ75   A0A0T6AY67   A0A1I8QDX9   E0VT76   B0W8E1   A0A182K8J4   A0A1B0G902   A0A336KZ48   U4US14   A0A1A9WRH1   W8ANN1   A0A1A9VSD6   A0A1A9Z5T7   A0A1B0G8C3   A0A1A9Z4V7   A0A1A9UQS4   A0A0Q5U6J1   A0A1B0B3L8   B4PFC5   A0A0J9RZW2   A0A1B0G581   A0A1W4VUR9   A0A0P8XTK4   A0A3B0K9C5   A0A1A9Z2Z5   A0A0Q5UKB6   A0A0R1E263   B3NE58   A0A0J9RYJ5   A0A0R1E3V8   B4IA68   A0A0J9UPV3   B4MKU9   P40421   A0A0P8XTZ4   A0A0R3P3C9   B3M4R3   A0A3B0KHY3   A0A0Q9WVD8   A0A0R3P3E4   A0A0R3P3H1   A0A0R3P7M8   B5DPA9   A0A1J1IGC9   A0A0Q9XDH4   B4IYR3   B4LG02   A0A0Q9XQA2   B4KV71   A0A0M4EZY5   A0A1A9Y029   B4GR08   A0A2T7PP07   A0A224Z6H9   A0A131YUK5   A0A369SL60   A0A044UXV0   A0A090LKG0   A7RNB7   A0A0N5BXR6   A0A0K0EJQ2   A0A2B4SS40   A0A1S3HU17   A0A0K0F6X9   A0A1I7VS43  

PDB

3H69     E-value=2.84228e-63,     Score=616

KEGG

101744368    K13807 serine/threonine-protein phosphatase with EF-hands [EC:3.1.3.16] | (RefSeq) serine/threonine-

GO

GO:0004721   GO:0005509   GO:0030145   GO:0050906   GO:0005506   GO:0005829   GO:0005634   GO:0004722   GO:0016021   GO:0043052   GO:0006470   GO:0007601   GO:0019722   GO:0005516   GO:0005737   GO:0004723   GO:0016059   GO:0007602   GO:0043025   GO:0016787   GO:0005515   GO:0016818   GO:0003707   GO:0051537  

Length:

732

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

7.50338999999999

Exp number, first 60 AAs:

0.00879

Total prob of N-in:

0.25924

outside

1  -  732

 

 

Pi

252.16079

Theta

186.796423

Tajima's D

0.987717

CLR

0.311684

CSRT

0.656917154142293

Interpretation

Uncertain