Gene

KWMTBOMO07819

Pre Gene Modal

BGIBMGA001219

Annotation

PREDICTED:_ethanolamine_kinase_[Papilio_machaon]

Location

Bomo_Chr13(-):7430772-7443662      View in EpiBrowser

Full name

Ethanolamine kinase      

Alternative Name

Protein easily shocked

Location in the cell

Cytoplasmic   Reliability : 1.226 PlasmaMembrane   Reliability : 1.108

CDS

ATGCATAGAGTTGAACTTGGAAAAGAGGTACAAAAAGATCCAATGGTATGGGATAAAATTGAACAATTCCTAAGTTTGTTGCCAGAGAAATTCTCTACAGAAGTCAAACACAATAGATTTGTGAGTAGCTTTGGGTCAGTAACTAAGCTAAGGATTGAATTTGAGCGTCTAAAGTCTCATCTAATCAAAACGGAGAGCCCAATAGTGTTTGCTCACAATGATTTGCTTCTAGGAAACGTTATCTTCAACAAAGATGAAGGGACCATCTCTTTCATAGACTATGAATATGCCAGTTACAATTATCAGGCGTTCGATATAGCTAATCATTTCAACGAATTTGTCGGATTATCAATTGAAGACATTGATTACCAAAGATATCCGAGTAAAGACTTCCAACTTGCTTGGATTAGAGTATATTTATCGGAATATTTAGGAACAATGACGCCTGACGCTAAAAGCGTAGATACAGTTTATGAAGAAGTACAAAAACTTTCGTTAGCTTCACATTTTCTTTGGGGTATATGGTCACTAGTGCAATTTGAACATTCTGATATTGATTTCGATTTCGGAAGGTATGCAGAAATACGTTTACAGCGATATTATCAAACAAAAAATGATATTTTAAGTGTATGTACTTAA

Protein

MHRVELGKEVQKDPMVWDKIEQFLSLLPEKFSTEVKHNRFVSSFGSVTKLRIEFERLKSHLIKTESPIVFAHNDLLLGNVIFNKDEGTISFIDYEYASYNYQAFDIANHFNEFVGLSIEDIDYQRYPSKDFQLAWIRVYLSEYLGTMTPDAKSVDTVYEEVQKLSLASHFLWGIWSLVQFEHSDIDFDFGRYAEIRLQRYYQTKNDILSVCT

Description

Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis.

Catalytic Activity

ATP + ethanolamine = ADP + H(+) + phosphoethanolamine

Similarity

Belongs to the choline/ethanolamine kinase family.

Keywords

Alternative splicing   ATP-binding   Complete proteome   Cytoplasm   Kinase   Lipid biosynthesis   Lipid metabolism   Nucleotide-binding   Phospholipid biosynthesis   Phospholipid metabolism   Phosphoprotein   Reference proteome   Transferase  

Feature

chain  Ethanolamine kinase
splice variant  In isoform G.

Uniprot

H9IVD9   A0A194RHT6   A0A2H1VLK0   A0A2A4J114   A0A194PE10   A0A0L7LJC1   + More
A0A212EME1   A0A1B0DLT2   A0A067QIM2   A0A1L8E3P9   A0A0K8TLL7   Q16UX5   A0A1Y1N783   A0A182P7L7   A0A182W4T5   A0A2J7PXA4   A0A1L8ED31   A0A182M9N0   A0A182UMP1   A0A1Q3FJ61   Q29GE0   A0A0A1X0W6   W8BJB8   B0WH47   A0A182T605   A0A182KY26   Q7QEI8   A0A1A9VWK0   A0A1B0A1D6   A0A1B0BLH5   A0A1A9YQC7   A0A3B0KE78   A0A182RHV2   A0A1B6MNL2   V5GUQ1   A0A336MXR1   B3N0U6   A0A1B6IDX1   A0A182UB63   A0A182YK58   T1PFM6   A0A0L0BW36   B4NEW5   A0A0M5J366   A0A1B6DMU5   A0A182X582   A0A1B0FCR2   A0A2M4BT60   B4L7Q0   A0A2M4BRA6   A0A2M4BR65   T1GU53   B4JJY2   P54352-2   D6X535   P54352   A0A182N908   A0A0K8TZU6   A0A023ETY5   B4PXQ8   B3NXD9   A0A023EMT2   B4MG95   A0A0R1EAE6   A0A182G1P3   A0A0Q5T4K5   A0A1W4WDE5   A0A1I8PK72   A0A1B6CIE0   A0A0K8WCP8   A0A2M3ZAX1   A0A1A9WHQ5   A0A182FM71   A0A151WRR4   A0A158NE75   A0A182Q509   A0A1B0C9X0   A0A182I9Q4   A0A0N0BCT5   A0A088A9M7   A0A151IDI5   A0A034VAH8   A0A182IME6   B4NUI5   A0A034V885   A0A154PDA3   A0A0L7RFN0   W5JVX3   F4X444   A0A1W4XEF8   E9IA48   A0A3R7PLU0   A0A1S6KZC0   A0A3P8ZZ15   A0A232FBQ7   E0W045   A0A1W5AEP7   A0A0T6B455   M3XLG4  

EC Number

2.7.1.82

Pubmed

19121390    26354079    26227816    22118469    24845553    26369729    + More
17510324    28004739    15632085    17994087    23185243    25830018    24495485    20966253    12364791    14747013    17210077    18057021    25244985    25315136    26108605    7923374    10731132    12537572    12537569    17372656    18327897    18362917    19820115    24945155    17550304    26483478    21347285    25348373    20920257    23761445    21719571    21282665    24330026    25069045    28648823    20566863    9215903   

EMBL

BABH01000950    BABH01000951    BABH01000952    BABH01000953    KQ460205    KPJ16890.1    + More
ODYU01003229    SOQ41710.1    NWSH01004427    PCG65130.1    KQ459606    KPI91263.1    JTDY01000893    KOB75530.1    AGBW02013857    OWR42647.1    AJVK01006808    KK853502    KDR07130.1    GFDF01000820    JAV13264.1    GDAI01002545    JAI15058.1    CH477612    EAT38330.1    GEZM01010845    GEZM01010844    GEZM01010843    JAV93772.1    NEVH01020859    PNF20957.1    GFDG01002149    JAV16650.1    AXCM01006140    GFDL01007522    JAV27523.1    CH379064    EAL32170.3    KRT07016.1    KRT07017.1    GBXI01009308    JAD04984.1    GAMC01007720    GAMC01007718    JAB98837.1    DS231932    EDS27498.1    AAAB01008846    EAA06461.5    JXJN01016356    OUUW01000011    SPP86610.1    GEBQ01002484    JAT37493.1    GALX01004528    JAB63938.1    UFQS01003664    UFQT01003664    SSX15847.1    SSX35192.1    CH902644    EDV34825.1    KPU75301.1    KPU75302.1    GECU01022580    GECU01018182    JAS85126.1    JAS89524.1    KA646708    AFP61337.1    JRES01001250    KNC24231.1    CH964239    EDW82284.2    CP012528    ALC49248.1    GEDC01015125    GEDC01010287    JAS22173.1    JAS27011.1    CCAG010001428    GGFJ01007124    MBW56265.1    CH933814    EDW05763.1    KRG07515.1    KRG07516.1    GGFJ01006372    MBW55513.1    GGFJ01006371    MBW55512.1    CAQQ02139792    CAQQ02139793    CH916370    EDV99884.1    L35603    L35604    AE014298    AY118437    BT025059    BT099812    KQ971382    EEZ97183.2    GDHF01032709    JAI19605.1    GAPW01001704    JAC11894.1    CM000162    EDX01894.2    KRK06419.1    KRK06420.1    KRK06421.1    CH954180    EDV46898.2    KQS30237.1    GAPW01002925    JAC10673.1    CH940672    EDW57418.1    KRF77765.1    KRK06422.1    JXUM01137480    KQ568584    KXJ68949.1    KQS30236.1    GEDC01024111    JAS13187.1    GDHF01016024    GDHF01003356    JAI36290.1    JAI48958.1    GGFM01004901    MBW25652.1    KQ982796    KYQ50602.1    ADTU01013096    ADTU01013097    AXCN02001403    AJWK01002980    APCN01001018    KQ435898    KOX69172.1    KQ977939    KYM98526.1    GAKP01019428    JAC39524.1    AXCP01008829    CH984024    EDX16632.1    GAKP01019426    JAC39526.1    KQ434869    KZC09238.1    KQ414606    KOC69613.1    ADMH02000145    ETN67618.1    GL888625    EGI58768.1    GL761987    EFZ22558.1    QCYY01001692    ROT76128.1    KC223178    AQT27081.1    NNAY01000455    OXU28274.1    DS235855    EEB19001.1    LJIG01009900    KRT82156.1    AFYH01035462    AFYH01035463    AFYH01035464    AFYH01035465    AFYH01035466    AFYH01035467    AFYH01035468    AFYH01035469    AFYH01035470    AFYH01035471   

Proteomes

UP000005204    UP000053240    UP000218220    UP000053268    UP000037510    UP000007151    + More
UP000092462    UP000027135    UP000008820    UP000075885    UP000075920    UP000235965    UP000075883    UP000075903    UP000001819    UP000002320    UP000075901    UP000075882    UP000007062    UP000078200    UP000092445    UP000092460    UP000092443    UP000268350    UP000075900    UP000007801    UP000075902    UP000076408    UP000095301    UP000037069    UP000007798    UP000092553    UP000076407    UP000092444    UP000009192    UP000015102    UP000001070    UP000000803    UP000007266    UP000075884    UP000002282    UP000008711    UP000008792    UP000069940    UP000249989    UP000192221    UP000095300    UP000091820    UP000069272    UP000075809    UP000005205    UP000075886    UP000092461    UP000075840    UP000053105    UP000005203    UP000078542    UP000075880    UP000000304    UP000076502    UP000053825    UP000000673    UP000007755    UP000192223    UP000283509    UP000265140    UP000215335    UP000009046    UP000192224    UP000008672   

PRIDE

H9IVD9    P54352   

Pfam

PF00096   zf-C2H2        + More
PF01490   Aa_trans

Interpro

IPR011009   Kinase-like_dom_sf        + More
IPR012934   Znf_AD       
IPR013057   AA_transpt_TM       
IPR013087   Znf_C2H2_type       
IPR020846   MFS_dom       
IPR036236   Znf_C2H2_sf       

SUPFAM

SSF56112   SSF56112        + More
SSF57667   SSF57667       

CDD

cd06174  MFS

ProteinModelPortal

H9IVD9   A0A194RHT6   A0A2H1VLK0   A0A2A4J114   A0A194PE10   A0A0L7LJC1   + More
A0A212EME1   A0A1B0DLT2   A0A067QIM2   A0A1L8E3P9   A0A0K8TLL7   Q16UX5   A0A1Y1N783   A0A182P7L7   A0A182W4T5   A0A2J7PXA4   A0A1L8ED31   A0A182M9N0   A0A182UMP1   A0A1Q3FJ61   Q29GE0   A0A0A1X0W6   W8BJB8   B0WH47   A0A182T605   A0A182KY26   Q7QEI8   A0A1A9VWK0   A0A1B0A1D6   A0A1B0BLH5   A0A1A9YQC7   A0A3B0KE78   A0A182RHV2   A0A1B6MNL2   V5GUQ1   A0A336MXR1   B3N0U6   A0A1B6IDX1   A0A182UB63   A0A182YK58   T1PFM6   A0A0L0BW36   B4NEW5   A0A0M5J366   A0A1B6DMU5   A0A182X582   A0A1B0FCR2   A0A2M4BT60   B4L7Q0   A0A2M4BRA6   A0A2M4BR65   T1GU53   B4JJY2   P54352-2   D6X535   P54352   A0A182N908   A0A0K8TZU6   A0A023ETY5   B4PXQ8   B3NXD9   A0A023EMT2   B4MG95   A0A0R1EAE6   A0A182G1P3   A0A0Q5T4K5   A0A1W4WDE5   A0A1I8PK72   A0A1B6CIE0   A0A0K8WCP8   A0A2M3ZAX1   A0A1A9WHQ5   A0A182FM71   A0A151WRR4   A0A158NE75   A0A182Q509   A0A1B0C9X0   A0A182I9Q4   A0A0N0BCT5   A0A088A9M7   A0A151IDI5   A0A034VAH8   A0A182IME6   B4NUI5   A0A034V885   A0A154PDA3   A0A0L7RFN0   W5JVX3   F4X444   A0A1W4XEF8   E9IA48   A0A3R7PLU0   A0A1S6KZC0   A0A3P8ZZ15   A0A232FBQ7   E0W045   A0A1W5AEP7   A0A0T6B455   M3XLG4  

PDB

4DA5     E-value=1.55616e-26,     Score=293

KEGG

101745087    K00894 ethanolamine kinase [EC:2.7.1.82] | (RefSeq) ethanolamine kinase

PATHWAY

00564    Glycerophospholipid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016301   GO:0016740   GO:0007616   GO:0008306   GO:0009612   GO:0005524   GO:0046959   GO:0004305   GO:0004103   GO:0001666   GO:0016319   GO:0016310   GO:0055059   GO:0006646   GO:0005737   GO:0007638   GO:0046337   GO:0007420   GO:0003676   GO:0008270   GO:0016021   GO:0005634  

Subcellular location

Cytoplasm  

Length:

212

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00736

Exp number, first 60 AAs:

1e-05

Total prob of N-in:

0.07174

outside

1  -  212

 

 

Pi

224.282757

Theta

164.577886

Tajima's D

0.494004

CLR

1.78919

CSRT

0.511974401279936

Interpretation

Uncertain