Gene

KWMTBOMO07811  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001223

Annotation

PREDICTED:_DEAD-box_helicase_Dbp80_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr13(-):7366285-7368302      View in EpiBrowser

Full name

DEAD-box helicase Dbp80      

Location in the cell

Cytoplasmic   Reliability : 3.556

CDS

ATGGCTAGCCAGTGGGGACAAAAGGCAGAAGAGTTGGAGATTTCAAATAAAGTTGCAGGGCTGGGCTTGGATAAAAAACATAATCAAGAAACAGATTCTGATGATGTACCTGATACCCCTAATGCAGCCGATACTTCTCTTTTAATGAAAATCATACGGCAAGGTCTAGTTGAATCTAAACTAGATATAGAAATACAGAGAAAAGACCCTAATTCACCATTGTATTCTGTAAAAACATTTGAAGCTTTGCATTTGAAGCCAAATTTACTGAAAGGGGTTTATGCTATGGGTTTTAATGCTCCATCTAAAATTCAAGAAACAGCACTTCCTACACTCTTAGCTGATCCTCCACAGAATATGATAGCCCAGTCACAATCAGGTACAGGAAAAACTGCTGCCTTTGTTTTAGCGATGTTAAGCAGAGTTGACTCTAACAAGAATTATCCTCAAGTATTGTGTCTTAGTCCCACATATGAACTAGCCATACAAACTGGTGAAGTTGCTGCAAAAATGGCAAAATTTTGTCCTGAAATAAAGTTAAAGTATGCAGTTAGAGGGGAAGAACTTCCCAGGGGTTCAAAAATCACAGATCACATTCTTATTGGTACTCCAGGAAAGATGTTTGATTGGGGTGTCAAGTTTGGCATGTTTGATATGGGTAAAATTAAAGTTTTTGTGTTAGACGAAGCAGATGTCATGATCAATCGACAAGGGCATCAAGACCAATGCATTAGAATTCATAAATGCTTACCATCAACATGTCAGATGATGTTTTTCTCTGCAACATATGGTACTGCAGTCATGCAATTTGCTGAGATAATTGTTTCTAATCCAATTATAATCAGACTTTTGAGAGAAGAAGAATCACTGGATAACATAAAACAATATTATGTAAAGTGCAAAAGTGCAGAAGACAAATATAGAGCAATTTGTAACATTTATGGTGTAATAACAATTGGTCAAGCAATTATATTTTGTCATACACGAAAGACTGCAAGTTGGTTGTCTGAAAAGATGTCAAAGGATGGTCACTCAGTGGCTGTCCTTTCTGGTGAATTGACAGTTGAGCAGAGAATTGCAGTACTGGATCGCTTTCGGGTGGGTCTTGAAAAAGTATTGATCACAACTAATGTTTTGTCTCGTGGAATTGATGTTGAACAAGTTACTTTAGTTGTCAATTTTGACATGCCCATGGACATGAATAGAAAAGCAGATTGTGAGACATATCTGCACAGAATTGGGAGAACTGGTAGATTTGGAAAAGCTGGTATTGCAATTAACCTCATAGACTCTCCACAAGCTATGGAGATCTGTACAGACATTGAAGCACACTTTGGTAAGAAAATTCAATTACTGGATATTGAAGATGCAGAAGAAATAGAAAAGATTGGGGCTTAA

Protein

MASQWGQKAEELEISNKVAGLGLDKKHNQETDSDDVPDTPNAADTSLLMKIIRQGLVESKLDIEIQRKDPNSPLYSVKTFEALHLKPNLLKGVYAMGFNAPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSRVDSNKNYPQVLCLSPTYELAIQTGEVAAKMAKFCPEIKLKYAVRGEELPRGSKITDHILIGTPGKMFDWGVKFGMFDMGKIKVFVLDEADVMINRQGHQDQCIRIHKCLPSTCQMMFFSATYGTAVMQFAEIIVSNPIIIRLLREEESLDNIKQYYVKCKSAEDKYRAICNIYGVITIGQAIIFCHTRKTASWLSEKMSKDGHSVAVLSGELTVEQRIAVLDRFRVGLEKVLITTNVLSRGIDVEQVTLVVNFDMPMDMNRKADCETYLHRIGRTGRFGKAGIAINLIDSPQAMEICTDIEAHFGKKIQLLDIEDAEEIEKIGA

Description

ATP-dependent RNA helicase involved in mRNA export from the nucleus.

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate

Similarity

Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.

Keywords

ATP-binding   Complete proteome   Cytoplasm   Helicase   Hydrolase   Membrane   mRNA transport   Nuclear pore complex   Nucleotide-binding   Nucleus   Phosphoprotein   Protein transport   Reference proteome   RNA-binding   Translocation   Transport  

Feature

chain  DEAD-box helicase Dbp80

Uniprot

H9IVE3   A0A0L7LKG7   A0A2A4JEX6   S4P8A0   A0A2H1VLL7   A0A212EMD1   + More
A0A194RH21   A0A194PJJ1   E2BX49   A0A026WE42   A0A2A3E322   A0A088ARQ2   E2APZ4   A0A195C3I4   A0A154PA56   A0A0J7L120   Q16UG1   A0A195E2Y9   A0A182PS36   A0A182GEU8   A0A182QUC5   F4X043   A0A182HJQ3   A0A182XK85   A0A182UUE6   A0A182KWW4   A0A182TD30   A0A182LYX0   Q7QDK9   A0A158NHK2   A0A195ETK3   U5EPK7   A0A182K236   A0A182NKT5   A0A182W0L9   A0A182Y4J6   A0A232EHR6   A0A084W7D1   A0A195AUV0   K7JBG9   A0A182R7Z2   Q16NC6   A0A182JAC5   A0A1Y1KN83   A0A2M4BKA5   A0A2M4BKK1   W5J526   B0W9D2   A0A1B0CDL7   A0A1Q3F113   A0A1Q3F0W9   A0A1Q3F117   A0A1L8DRM6   A0A336N4J2   A0A1L8DRQ5   A0A0K8UD04   A0A034WWN2   A0A1A9X3Y6   A0A1I8NXV0   A0A0A1WUX9   W8C7S6   V5GU46   T1P9N9   A0A0K8UR68   A0A067R887   A0A336NAL8   A0A1A9XR48   A0A1A9V6C4   A0A2J7RR65   A0A2J7RR68   Q95PU7   A0A1B0BQL0   A0A1B0GE19   A0A1A9ZHF0   A0A0L0BNE6   D6WJW8   A0A0J9R5I8   B4NA05   B3MWW3   A0A182FL75   O61305   B4KV95   K7JBH1   B3NJ83   A0A1B6CZZ3   A0A1B6D5Z6   B4NTI5   A0A232EHT1   A0A0M4ECH7   A0A1J1IYA4   A0A1B6I7W1   A0A1B6J5L2   B4LE03   A0A1B6GWE7   Q0ZIV2   A0A3B0KT15   B4IYN9   E9FYK7   E0VXB1   A0A1B6MQS9  

EC Number

3.6.4.13

Pubmed

19121390    26227816    23622113    22118469    26354079    20798317    + More
24508170    30249741    17510324    26483478    21719571    20966253    12364791    14747013    17210077    21347285    25244985    28648823    24438588    20075255    28004739    20920257    23761445    25348373    25830018    24495485    24845553    11867546    26108605    18362917    19820115    22936249    17994087    9565667    10731132    12537572    17372656    18327897    16648646    21292972    20566863   

EMBL

BABH01000967    JTDY01000769    KOB75942.1    NWSH01001710    PCG70369.1    GAIX01009605    + More
JAA82955.1    ODYU01003229    SOQ41717.1    AGBW02013857    OWR42638.1    KQ460205    KPJ16882.1    KQ459606    KPI91255.1    GL451202    EFN79768.1    KK107293    QOIP01000005    EZA53299.1    RLU22463.1    KZ288427    PBC25874.1    GL441645    EFN64481.1    KQ978350    KYM94738.1    KQ434856    KZC08707.1    LBMM01001509    KMQ96174.1    CH477622    EAT38176.1    KQ979763    KYN19277.1    JXUM01058749    JXUM01058750    KQ562016    KXJ76898.1    AXCN02000304    GL888489    EGI60184.1    APCN01002203    AXCM01000643    AAAB01008851    EAA07398.4    ADTU01015876    ADTU01015877    KQ981975    KYN31585.1    GANO01000132    JAB59739.1    NNAY01004450    OXU17883.1    ATLV01021211    KE525314    KFB46125.1    KQ976737    KYM75951.1    AAZX01013108    CH477829    EAT35848.1    AXCP01007741    GEZM01080837    JAV62028.1    GGFJ01004349    MBW53490.1    GGFJ01004350    MBW53491.1    ADMH02002195    ETN57879.1    DS231863    EDS39992.1    AJWK01007998    GFDL01013798    JAV21247.1    GFDL01013861    JAV21184.1    GFDL01013794    JAV21251.1    GFDF01005023    JAV09061.1    UFQS01005011    UFQT01005011    SSX16662.1    SSX35857.1    GFDF01005030    JAV09054.1    GDHF01027795    JAI24519.1    GAKP01000220    JAC58732.1    GBXI01011851    JAD02441.1    GAMC01003439    JAC03117.1    GALX01000782    JAB67684.1    KA644653    AFP59282.1    GDHF01023130    JAI29184.1    KK852675    KDR18709.1    UFQS01005121    UFQT01005121    SSX16717.1    SSX35908.1    NEVH01000611    PNF43328.1    PNF43329.1    AJ318937    CAC87273.1    JXJN01018679    CCAG010012081    JRES01001702    KNC20789.1    KQ971342    EFA03913.1    CM002910    CM002911    CM002912    KMY91467.1    KMY91470.1    KMY91508.1    KMY91563.1    KMZ01349.1    CH964232    EDW81760.1    CH902627    EDV33943.2    AE014296    AF005239    CH933809    EDW19435.2    AAZX01002871    CH954178    EDV52866.2    GEDC01018276    JAS19022.1    GEDC01016222    JAS21076.1    CH983164    EDX15643.1    OXU17882.1    CP012525    ALC43121.1    CVRI01000064    CRL05135.1    GECU01024670    JAS83036.1    GECU01013259    JAS94447.1    CH940647    EDW70046.1    GECZ01003030    JAS66739.1    DQ426901    DQ426902    ABD90551.1    OUUW01000014    SPP88371.1    CH916366    EDV96576.1    GL732527    EFX87750.1    DS235830    EEB18017.1    GEBQ01001711    JAT38266.1   

Proteomes

UP000005204    UP000037510    UP000218220    UP000007151    UP000053240    UP000053268    + More
UP000008237    UP000053097    UP000279307    UP000242457    UP000005203    UP000000311    UP000078542    UP000076502    UP000036403    UP000008820    UP000078492    UP000075885    UP000069940    UP000249989    UP000075886    UP000007755    UP000075840    UP000076407    UP000075903    UP000075882    UP000075902    UP000075883    UP000007062    UP000005205    UP000078541    UP000075881    UP000075884    UP000075920    UP000076408    UP000215335    UP000030765    UP000078540    UP000002358    UP000075900    UP000075880    UP000000673    UP000002320    UP000092461    UP000091820    UP000095300    UP000027135    UP000092443    UP000078200    UP000235965    UP000092460    UP000092444    UP000092445    UP000037069    UP000007266    UP000007798    UP000007801    UP000069272    UP000000803    UP000009192    UP000008711    UP000000304    UP000092553    UP000183832    UP000008792    UP000268350    UP000001070    UP000000305    UP000009046   

PRIDE

H9IVE3    O61305   

Pfam

PF00271   Helicase_C        + More
PF00270   DEAD
PF00719   Pyrophosphatase

Interpro

IPR027417   P-loop_NTPase        + More
IPR014001   Helicase_ATP-bd       
IPR001650   Helicase_C       
IPR014014   RNA_helicase_DEAD_Q_motif       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR036649   Pyrophosphatase_sf       
IPR008162   Pyrophosphatase       

SUPFAM

SSF52540   SSF52540        + More
SSF50324   SSF50324       

Gene 3D

3.90.80.10    

CDD

cd00079  HELICc
cd00412  pyrophosphatase

ProteinModelPortal

H9IVE3   A0A0L7LKG7   A0A2A4JEX6   S4P8A0   A0A2H1VLL7   A0A212EMD1   + More
A0A194RH21   A0A194PJJ1   E2BX49   A0A026WE42   A0A2A3E322   A0A088ARQ2   E2APZ4   A0A195C3I4   A0A154PA56   A0A0J7L120   Q16UG1   A0A195E2Y9   A0A182PS36   A0A182GEU8   A0A182QUC5   F4X043   A0A182HJQ3   A0A182XK85   A0A182UUE6   A0A182KWW4   A0A182TD30   A0A182LYX0   Q7QDK9   A0A158NHK2   A0A195ETK3   U5EPK7   A0A182K236   A0A182NKT5   A0A182W0L9   A0A182Y4J6   A0A232EHR6   A0A084W7D1   A0A195AUV0   K7JBG9   A0A182R7Z2   Q16NC6   A0A182JAC5   A0A1Y1KN83   A0A2M4BKA5   A0A2M4BKK1   W5J526   B0W9D2   A0A1B0CDL7   A0A1Q3F113   A0A1Q3F0W9   A0A1Q3F117   A0A1L8DRM6   A0A336N4J2   A0A1L8DRQ5   A0A0K8UD04   A0A034WWN2   A0A1A9X3Y6   A0A1I8NXV0   A0A0A1WUX9   W8C7S6   V5GU46   T1P9N9   A0A0K8UR68   A0A067R887   A0A336NAL8   A0A1A9XR48   A0A1A9V6C4   A0A2J7RR65   A0A2J7RR68   Q95PU7   A0A1B0BQL0   A0A1B0GE19   A0A1A9ZHF0   A0A0L0BNE6   D6WJW8   A0A0J9R5I8   B4NA05   B3MWW3   A0A182FL75   O61305   B4KV95   K7JBH1   B3NJ83   A0A1B6CZZ3   A0A1B6D5Z6   B4NTI5   A0A232EHT1   A0A0M4ECH7   A0A1J1IYA4   A0A1B6I7W1   A0A1B6J5L2   B4LE03   A0A1B6GWE7   Q0ZIV2   A0A3B0KT15   B4IYN9   E9FYK7   E0VXB1   A0A1B6MQS9  

PDB

6B4K     E-value=7.75449e-163,     Score=1473

KEGG

101746250    K18655 ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13] | (RefSeq) DEAD-box helicase Dbp80

GO

GO:0005524   GO:0003676   GO:0004386   GO:0003743   GO:0006796   GO:0000287   GO:0005737   GO:0004427   GO:0051028   GO:0031965   GO:0044614   GO:0015031   GO:0003723   GO:0005215   GO:0009081   GO:0004817   GO:0006423   GO:0016021   GO:0022891   GO:0003707   GO:0051537  

Subcellular location

Cytoplasm  
Nucleus  
Nuclear pore complex  
Nucleus membrane  

Length:

465

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.79239

Exp number, first 60 AAs:

0

Total prob of N-in:

0.04016

outside

1  -  465

 

 

Pi

147.651005

Theta

162.520286

Tajima's D

-0.282133

CLR

0.104904

CSRT

0.295985200739963

Interpretation

Uncertain