Pre Gene Modal
BGIBMGA000919
Annotation
PREDICTED:_histone-lysine_N-methyltransferase_SUV420H1_[Amyelois_transitella]
Full name
Histone-lysine N-methyltransferase
Location in the cell
Nuclear Reliability : 4.654
Sequence
CDS
ATGATTTGTGTATCCAGAATGGTTGTTGGATCAGCGTCTTACCCTGGAAGGCAAGTGCTCCACAAGATGCAGCCGATGGGTATGACTCCTCGCGAGCTGTCCGAATACGATGATCTAGCAACGGCTCTAATCGTGGACCCATATCTAGGCATCACGACACACAAGATGAATATCCGCTATAGACCTTTAAAAACAAACAAGGAAGAATTAAAAAACATTATAAAAGAGTTTATTCATACACAGGATTATAATAAAGCTTATTCAAAACTAGCCAATGGTGAATGGATACCTCGACATTTTAGTAAAAATAAACATCAGCAGACCAAGTTTCGAGACCATATTTATCGTTATTTACGAATTTTTGACAAGAAAGCGGGATTTGTTATAGAACCATGCTATAGATATTCATTAGAAGGCAGAGTAGGAGCAAAAATTTCATCAACAAAAAAGTTTTTCAAACATGAAAGAATAGATTTCTTAGTTGGGTGCATAGCAGAAATGACTGAAGAAGAAGAAAAACAATTATTACATCCTGGAAAAAATGACTTCTCAGTTATGTATAGCTGTAGAAAAAATTGTGCTCAGTTATGGCTTGGACCTGCTGCTTATATTAATCATGATTGTAGACCAACATGTACATTTGAAGCTACAGATCGTGGAAAGGCATTTGTTCGAGTGCTGAGAGATATAGAGCCTGGTGAAGAAATTACTTGTTACTATGGTGAAGATTTTTTTGGAAATAGCAATTGTTACTGTGAATGTGAAACTTGTGAAAGAAGGGGAAAAGGGGCATTTTCAGTTGAAAGTTCACATAATGATGAACAATCCACAAGATATAGATTTCGAGAAACAGATAACAGAATAAACAGAACAAAAGCAAAGCAGGTTCAAAAATCATCAAATGTAAAAAATTCTGATAAGACTCGAATATCCAGTAGGCAAAATTCTAGTATAGTATCTCCTCTTAGTATGAAAGAAATGAAACAAAAAGGCTTAACAAAGTATGATGCAGAATTATTGATAGCTCAGGGTTGCATAGCTGATGTTTTAGATGGCACTACTGATAAAGAAGACAAAGGGAGCAGAGAATCCTCCACATCTAGTAGGGGTGAAAGGTTACGAAAAAGGACAGATAGTAACAAAACTATTAATGGTGTACATGGCACAGGAAAACGCAGAGCACCTCCTTCTCGTTGTTGTAGCACTGCCAGTTCCCGAAGCAGTAGAGATTCTCATTCAGGAATTGTGCTAAGAAGTCATAAACGCCTTCTTGATACGTGCATTCAACCCAGTTTCCCTAAGATAAAAAATGGATCAAAAGTAGGTTCAGACATAAAATATGAAAGAAATGTGAATACACCAAAAGAAGAGGCTGATTTACCTAGCACTTTAGAAATTTCCAATTTTGACATTAAACCCGACCTACCTATTGTAAATGATAATGAACACAGTTCAGATTTGAATTCTTTTGTGTATACTGATACCCATTTAGGTGGTAAGAATTGTGATAAAAAAGAATCTCTAACTGAAACAGACCTGCCTATAGCTACAGCGACAGAGGATAAAATAGAAATTATAGAAAGTAAATCAAAGGTTCAAAAAGAACCTGATGAAATTGATTGTACGGTGAGAAATGAAAATTCGTCTTTAAAGAGTGGAATTGATTTTAGGGAAAATGTAAATCCAAGTGAGCCTAACAATAGTAAAAACAATAAGGTTCAAAAAATAGAAATAAGCAATAGAAGTGATGAGTCAAAAAGAGAAGTTGATTCTGGACCTCCTTGGTTAGTGGATAATTCTAATAAAAGCAGTGATTGCCCTTGTACTCCACCAAGGCGTGGATTGAAGTTGACATTACGTGTAAAACGAAGTCCTGTTGTTGAAGAGGTAATGGATTGTGGAGCACCTGCTGAAGCACCAGAGTATGAAGTTTTACGATTAGAAGGTGTCGATCCCGAAACTGCTAGACGCTTGAAGAAACGACGTCGATCCAAGGAACGACATCGAAAACATAGTCCTGTCCGTCCTCTGCCTCCAATGAAACGCCTAAGATTAATTTTTGGCAACGAAAGTCGCACTATCGATTTGCCTACAGCTTTATCAGCAGACTGA
Protein
MICVSRMVVGSASYPGRQVLHKMQPMGMTPRELSEYDDLATALIVDPYLGITTHKMNIRYRPLKTNKEELKNIIKEFIHTQDYNKAYSKLANGEWIPRHFSKNKHQQTKFRDHIYRYLRIFDKKAGFVIEPCYRYSLEGRVGAKISSTKKFFKHERIDFLVGCIAEMTEEEEKQLLHPGKNDFSVMYSCRKNCAQLWLGPAAYINHDCRPTCTFEATDRGKAFVRVLRDIEPGEEITCYYGEDFFGNSNCYCECETCERRGKGAFSVESSHNDEQSTRYRFRETDNRINRTKAKQVQKSSNVKNSDKTRISSRQNSSIVSPLSMKEMKQKGLTKYDAELLIAQGCIADVLDGTTDKEDKGSRESSTSSRGERLRKRTDSNKTINGVHGTGKRRAPPSRCCSTASSRSSRDSHSGIVLRSHKRLLDTCIQPSFPKIKNGSKVGSDIKYERNVNTPKEEADLPSTLEISNFDIKPDLPIVNDNEHSSDLNSFVYTDTHLGGKNCDKKESLTETDLPIATATEDKIEIIESKSKVQKEPDEIDCTVRNENSSLKSGIDFRENVNPSEPNNSKNNKVQKIEISNRSDESKREVDSGPPWLVDNSNKSSDCPCTPPRRGLKLTLRVKRSPVVEEVMDCGAPAEAPEYEVLRLEGVDPETARRLKKRRRSKERHRKHSPVRPLPPMKRLRLIFGNESRTIDLPTALSAD
Summary
Catalytic Activity
L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine
Similarity
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
Uniprot
EC Number
2.1.1.43
EMBL
Proteomes
PRIDE
Pfam
PF00856 SET
Interpro
Gene 3D
ProteinModelPortal
PDB
4BUP
E-value=3.16411e-76,
Score=728
Ontologies
GO
PANTHER
Topology
Length:
703
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.00528
Exp number, first 60 AAs:
0.00528
Total prob of N-in:
0.00049
outside
1 - 703
Population Genetic Test Statistics
Pi
244.626086
Theta
203.879036
Tajima's D
0.304947
CLR
52.763772
CSRT
0.458227088645568
Interpretation
Uncertain
