Gene

KWMTBOMO07788  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001237

Annotation

branched-chain-amino-acid_transaminase_[Spodoptera_litura]

Location

Bomo_Chr13(-):6843590-6854275      View in EpiBrowser

Full name

Branched-chain-amino-acid aminotransferase      

Location in the cell

Mitochondrial   Reliability : 2.179

CDS

ATGCCTATTAGACGTAGCCAGGTCTTGGTGAAATGGATATTCGAGAACCAACACAAGCTGCAGACTATTCGATGGTGTAGCTCTTCGCTGCGGTACAAAGAGCTAGAAGACTCAGTGCAGGCGGACCACGTGGCACCATCGCCCACGCAAAAGCCACACCCACAAATTACACCTGAAATCTCCTTCAAGTACGAAGACTTGCAAGTACGACTCGCGGCGCCGTATCAGCTCACCCCGAAACCCGAAGCTAAGGAACTAGGTTTCGGAAAGTATTTCACCGATCATATGCTCAAAATTTATTATCACAAGGAACTCGGGGGATGGCAAAAACCGGAGATCATGCCATTCGAGAACTTAAATATACATCCCGCCGCGAAGGCACTTCATTACGCCATACAATTATTTGAAGGATTGAAAGCGTACCGAGGTGTTGATGATAAAATACGATTGTTCAGGCCGGAACTTAACATGGAAAGGATGAACCTCGCAGCCCAGAGGTCCGGCTTGCCAATGTTCGACGGAGAAGAGCTCGTTCAATGCATAAAACGATTAGTACAAATTGACCAGGAATGGGTTCCGCATTCAGAAACGTCGACCCTTTATATCCGACCAACGTTAATAGGGATCGAGCCCACTTTCGGAATAATGGCGCCGGAGTCGGCATTGCTGTTTGTAATCCTGAGTCCAGTGAGCGCGTACTACAAGGCGAGCAGTGATGGAGCGGTCTCAATATTCGCTGATCCCAATGTCGTACGCGCCTTCCCTGGAGGAGTTGGAAACAGAAAGGTCGGCTCTAATTACGGACCCACTATAGAGGCGACAGCGCGAGCTGCAAAATTGGGGCACCATCAAGTGCTATGGCTCTTTGGTCCAGATCACCAATTAACAGAGGTCGGCGCCATGAATATTTTTATGGTGCACATCAACGATCAAGGAGATAAACAATTGAGTACGCCGCCACTGAACGGTTTGATATTGCCCGGAGTGACGCGTCGCTCCATCATCGAGCTGGCGAGCCAGTGGGAGGATATCGTCGTCAGAGAGGAAGTCATCACAATGGATCGCGTCATACAACTCAACCAACAAGGAAGGTTGCTAGAAATGTTCGGCGCGGGTACAGCCGTCATCATCAGCCCGATTAGCAGGGTCGGCTTCCTCGAACAAAACATTGAAATTCCCACGATGAAACAGTCGAACCCCGTGTTCCAACGAGTGAAGGACACGCTGCTCGCGATCCAATACGGACACGTGGAGCACCCGTACGCTAAGTCCAAAGCGTGA

Protein

MPIRRSQVLVKWIFENQHKLQTIRWCSSSLRYKELEDSVQADHVAPSPTQKPHPQITPEISFKYEDLQVRLAAPYQLTPKPEAKELGFGKYFTDHMLKIYYHKELGGWQKPEIMPFENLNIHPAAKALHYAIQLFEGLKAYRGVDDKIRLFRPELNMERMNLAAQRSGLPMFDGEELVQCIKRLVQIDQEWVPHSETSTLYIRPTLIGIEPTFGIMAPESALLFVILSPVSAYYKASSDGAVSIFADPNVVRAFPGGVGNRKVGSNYGPTIEATARAAKLGHHQVLWLFGPDHQLTEVGAMNIFMVHINDQGDKQLSTPPLNGLILPGVTRRSIIELASQWEDIVVREEVITMDRVIQLNQQGRLLEMFGAGTAVIISPISRVGFLEQNIEIPTMKQSNPVFQRVKDTLLAIQYGHVEHPYAKSKA

Catalytic Activity

2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate
2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate
2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate

Cofactor

pyridoxal 5'-phosphate

Similarity

Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

Feature

chain  Branched-chain-amino-acid aminotransferase

Uniprot

H9IVF7   A0A0F6TN66   A0A3S2NNE8   A0A194RLK0   B2DBI4   A0A212FI32   + More
A0A194PJG6   A0A2A4JT17   B4NEH1   W8C5Q1   B4MEI3   B4L1S1   A0A1W4V7F7   B4JLQ2   B4Q2B4   A0A0M3QZT2   D6WAG1   Q29IR8   B4H2W7   A0A3B0JEP8   A0A1Q3F112   Q9VYD5   B3NWN8   A0A0L0BTI6   A0A182URY9   A0A336LH67   A0A0K8V020   A0A1I8PIY8   B3MXN6   A0A182I9Q3   A0A182X583   B4IGS4   A0A182R0B7   A0A182W4T6   A0A182P7L6   A0A182LUI4   Q7QEI9   A0A1B0CFE6   B0X8N7   A0A0A1XJN5   A0A182K4T1   U5EJ01   A0A182RHV1   A0A182UCF6   A0A034VU07   A0A182YK57   T1PBX0   A0A1L8E2K2   A0A1Y1MMS7   A0A1I8MEC9   E2BI29   T1DS96   A0A2M3ZZU3   A0A182J412   A0A2M4BNL2   A0A182FM70   A0A2M4AES4   A0A1A9UUU7   A0A182T1E4   A0A1B0GFE6   A0A1A9W260   A0A1J1ICL7   A0A2M3Z0I3   A0A1B0AX39   A0A2M3Z096   A0A182N907   W5JWW1   A0A182H5Y8   A0A0A9X9B4   A0A084WF31   A0A1A9X7N1   F4WNG0   E2A8V2   A0A026WLB5   A0A146L409   A0A151IM55   A0A067RV27   A0A195EBU0   A0A151WV76   A0A158NW63   A0A195B7E5   A0A232EUM0   A0A154PQZ9   A0A088APL3   N6TNF5   K7J397   A0A195FWC1   A0A1B6F6K9   A0A1B6I3Z6   A0A1B6HJ33   A0A1B6KV56   A0A1W4WQV0   A0A1B6CGK1   R4WDX4   A0A0N0U4E6   A0A1B0AK39   A0A0C9QW79   A0A2A3EKT0   A0A0P4VNW2   A0A2J7PYH4  

EC Number

2.6.1.42

Pubmed

19121390    26354079    18712529    22118469    17994087    24495485    + More
17550304    18362917    19820115    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    26108605    12364791    14747013    17210077    25830018    25348373    25244985    25315136    28004739    20798317    20920257    23761445    26483478    25401762    24438588    21719571    24508170    30249741    26823975    24845553    21347285    28648823    23537049    20075255    23691247    27129103   

EMBL

BABH01001025    KP253078    AKE50541.1    RSAL01000208    RVE44283.1    KQ460205    + More
KPJ16861.1    AB264664    BAG30743.1    AGBW02008449    OWR53377.1    KQ459606    KPI91230.1    NWSH01000724    PCG74603.1    CH964239    EDW82140.1    GAMC01004724    JAC01832.1    CH940664    EDW62958.2    CH933810    EDW06724.1    CH916371    EDV91663.1    CM000162    EDX01575.2    CP012528    ALC49929.1    KQ971312    EEZ98004.1    CH379063    EAL32585.2    CH479204    EDW30684.1    OUUW01000003    SPP78662.1    GFDL01013804    JAV21241.1    AE014298    BT004848    AAF48268.2    AAO45204.1    CH954180    EDV47200.2    JRES01001360    KNC23357.1    UFQS01002087    UFQT01002087    SSX13172.1    SSX32611.1    GDHF01024630    GDHF01020067    GDHF01006877    JAI27684.1    JAI32247.1    JAI45437.1    CH902630    EDV38501.1    APCN01001017    APCN01001018    CH480836    EDW49024.1    AXCN02001403    AXCM01006140    AAAB01008846    EAA06463.3    AJWK01010033    DS232495    EDS42629.1    GBXI01003192    JAD11100.1    GANO01002426    JAB57445.1    GAKP01013371    GAKP01013370    JAC45582.1    KA646179    AFP60808.1    GFDF01001136    JAV12948.1    GEZM01029665    JAV86000.1    GL448433    EFN84655.1    GAMD01001594    JAA99996.1    GGFK01000597    MBW33918.1    AXCP01007463    AXCP01007464    AXCP01007465    GGFJ01005390    MBW54531.1    GGFK01005965    MBW39286.1    CCAG010011289    CCAG010011290    CVRI01000044    CRK96718.1    GGFM01001197    MBW21948.1    JXJN01004994    JXJN01004995    JXJN01004996    GGFM01001198    MBW21949.1    ADMH02000145    ETN67619.1    JXUM01113009    KQ565647    KXJ70813.1    GBHO01029939    GBHO01029938    GBRD01002181    GBRD01002180    JAG13665.1    JAG13666.1    JAG63640.1    ATLV01023288    KE525342    KFB48825.1    GL888237    EGI64153.1    GL437663    EFN70181.1    KK107154    QOIP01000001    EZA56830.1    RLU27414.1    GDHC01016000    JAQ02629.1    KQ977063    KYN05967.1    KK852446    KDR23724.1    KQ979074    KYN22695.1    KQ982706    KYQ51832.1    ADTU01027822    ADTU01027823    ADTU01027824    KQ976565    KYM80443.1    NNAY01002109    OXU22053.1    KQ435066    KZC14345.1    APGK01017059    APGK01017060    KB739995    KB632192    ENN82024.1    ERL89875.1    KQ981215    KYN44612.1    GECZ01025344    GECZ01023942    JAS44425.1    JAS45827.1    GECU01026091    GECU01002953    JAS81615.1    JAT04754.1    GECU01033111    GECU01030272    GECU01029522    GECU01010770    GECU01004345    JAS74595.1    JAS77434.1    JAS78184.1    JAS96936.1    JAT03362.1    GEBQ01024625    JAT15352.1    GEDC01024795    GEDC01000097    JAS12503.1    JAS37201.1    AK417949    BAN21164.1    KQ435822    KOX72274.1    GBYB01004927    JAG74694.1    KZ288219    PBC32327.1    GDKW01002554    JAI54041.1    NEVH01020348    PNF21393.1   

Proteomes

UP000005204    UP000283053    UP000053240    UP000007151    UP000053268    UP000218220    + More
UP000007798    UP000008792    UP000009192    UP000192221    UP000001070    UP000002282    UP000092553    UP000007266    UP000001819    UP000008744    UP000268350    UP000000803    UP000008711    UP000037069    UP000075903    UP000095300    UP000007801    UP000075840    UP000076407    UP000001292    UP000075886    UP000075920    UP000075885    UP000075883    UP000007062    UP000092461    UP000002320    UP000075881    UP000075900    UP000075902    UP000076408    UP000095301    UP000008237    UP000075880    UP000069272    UP000078200    UP000075901    UP000092444    UP000091820    UP000183832    UP000092460    UP000075884    UP000000673    UP000069940    UP000249989    UP000030765    UP000092443    UP000007755    UP000000311    UP000053097    UP000279307    UP000078542    UP000027135    UP000078492    UP000075809    UP000005205    UP000078540    UP000215335    UP000076502    UP000005203    UP000019118    UP000030742    UP000002358    UP000078541    UP000192223    UP000053105    UP000092445    UP000242457    UP000235965   

PRIDE

H9IVF7    Q9VYD5   

Pfam

PF01063   Aminotran_4        + More
PF01992   vATP-synt_AC39

Interpro

IPR005786   B_amino_transII        + More
IPR001544   Aminotrans_IV       
IPR033939   BCAT_family       
IPR036038   Aminotransferase-like       
IPR018300   Aminotrans_IV_CS       
IPR002843   ATPase_V0-cplx_csu/dsu       
IPR016727   ATPase_V0-cplx_dsu       
IPR036079   ATPase_su_C-like       

SUPFAM

SSF56752   SSF56752        + More
SSF103486   SSF103486       

CDD

cd01557  BCAT_beta_family

ProteinModelPortal

H9IVF7   A0A0F6TN66   A0A3S2NNE8   A0A194RLK0   B2DBI4   A0A212FI32   + More
A0A194PJG6   A0A2A4JT17   B4NEH1   W8C5Q1   B4MEI3   B4L1S1   A0A1W4V7F7   B4JLQ2   B4Q2B4   A0A0M3QZT2   D6WAG1   Q29IR8   B4H2W7   A0A3B0JEP8   A0A1Q3F112   Q9VYD5   B3NWN8   A0A0L0BTI6   A0A182URY9   A0A336LH67   A0A0K8V020   A0A1I8PIY8   B3MXN6   A0A182I9Q3   A0A182X583   B4IGS4   A0A182R0B7   A0A182W4T6   A0A182P7L6   A0A182LUI4   Q7QEI9   A0A1B0CFE6   B0X8N7   A0A0A1XJN5   A0A182K4T1   U5EJ01   A0A182RHV1   A0A182UCF6   A0A034VU07   A0A182YK57   T1PBX0   A0A1L8E2K2   A0A1Y1MMS7   A0A1I8MEC9   E2BI29   T1DS96   A0A2M3ZZU3   A0A182J412   A0A2M4BNL2   A0A182FM70   A0A2M4AES4   A0A1A9UUU7   A0A182T1E4   A0A1B0GFE6   A0A1A9W260   A0A1J1ICL7   A0A2M3Z0I3   A0A1B0AX39   A0A2M3Z096   A0A182N907   W5JWW1   A0A182H5Y8   A0A0A9X9B4   A0A084WF31   A0A1A9X7N1   F4WNG0   E2A8V2   A0A026WLB5   A0A146L409   A0A151IM55   A0A067RV27   A0A195EBU0   A0A151WV76   A0A158NW63   A0A195B7E5   A0A232EUM0   A0A154PQZ9   A0A088APL3   N6TNF5   K7J397   A0A195FWC1   A0A1B6F6K9   A0A1B6I3Z6   A0A1B6HJ33   A0A1B6KV56   A0A1W4WQV0   A0A1B6CGK1   R4WDX4   A0A0N0U4E6   A0A1B0AK39   A0A0C9QW79   A0A2A3EKT0   A0A0P4VNW2   A0A2J7PYH4  

PDB

2COJ     E-value=2.53828e-107,     Score=994

KEGG

101736408    K00826 branched-chain amino acid aminotransferase [EC:2.6.1.42] | (RefSeq) branched-chain-amino-acid

PATHWAY

00270    Cysteine and methionine metabolism - Bombyx mori (domestic silkworm)
00280    Valine, leucine and isoleucine degradation - Bombyx mori (domestic silkworm)
00290    Valine, leucine and isoleucine biosynthesis - Bombyx mori (domestic silkworm)
00770    Pantothenate and CoA biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01210    2-Oxocarboxylic acid metabolism - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)

GO

GO:0052656   GO:0052655   GO:0009082   GO:0052654   GO:0004084   GO:0005739   GO:0005737   GO:0009099   GO:0009098   GO:0033179   GO:0015078   GO:0015991   GO:0009081   GO:0003824   GO:0008152   GO:0004817   GO:0006423   GO:0016021   GO:0022891   GO:0003707   GO:0051537  

PANTHER

PTHR11028  

Length:

426

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.41031

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01070

outside

1  -  426

 

 

Pi

317.157157

Theta

210.736871

Tajima's D

1.190976

CLR

0.081913

CSRT

0.710814459277036

Interpretation

Uncertain