Gene

KWMTBOMO07778

Pre Gene Modal

BGIBMGA001240

Annotation

PREDICTED:_CD151_antigen_[Bombyx_mori]

Location

Bomo_Chr13(-):6659545-6662072      View in EpiBrowser

Full name

Tetraspanin       + More
Multifunctional fusion protein      
CTP synthase      

Alternative Name

UTP--ammonia ligase

Location in the cell

PlasmaMembrane   Reliability : 3.453

CDS

ATGGCAGCAGGCCTCACCATGTGTGCGACGGCTGCTCTTGGCTGCTGGGCAACCTATTTACCCGGATATGCCGCTTTGAGTATCTACTTCTTAATAGTTCTGTCTTTGCTATTGTGCGAGTGTGCTGGAGGCGTGTTAGCTGCAGTATGGCCGCGATGTCTGGGACTTGAAAACGCACGAGGGGGCTCTGTCGGAGCTCTGCAAAGCTATTATGCTATGCCCGACTTTGAACAATTCACTGCGTCTGTAGATTTAGCGCAAACAGAGTTGCAGTGTTGCGGTATGACAGATGCTCGAAACTACGACATGTCCGTATGGCAACTGAGGAGGCTGGGTCCGCGCGGAATGGCCGTACCGTTGAGTTGCTGCGTGCAAATCGAAGAGAACATCTCGTATCTGAACCCGATGCCGGTCAATTTATCGCGCTGTCAGGAGTATCAACCTAACCCTGTTTATCGACATGTTCCGGGCTGTATCGGTAAACTTGAAGAGTGGTACCAGAAACAATATTTTGTCCTCATGCTGAGCATCTTCATATTTGCTGTATTCAAACTGGGAGTTTTGTTAAGCACTGTATTTTCATGTATCCGACTCCGTCAAAGGAGACAAGTACTACATACAGTTACAGTTAAATCCATTGATCACGCAACGAATGAAAATATGTACGGTTCGGGAGTTCGCGAAGACCACATAACAGCCAAATATATCCAGCCGGATAATTATTACAGTCCAAGAGTTCGAAACCCTCGTATTTTTACGAGCAAACCGAACGAAATTATATGA

Protein

MAAGLTMCATAALGCWATYLPGYAALSIYFLIVLSLLLCECAGGVLAAVWPRCLGLENARGGSVGALQSYYAMPDFEQFTASVDLAQTELQCCGMTDARNYDMSVWQLRRLGPRGMAVPLSCCVQIEENISYLNPMPVNLSRCQEYQPNPVYRHVPGCIGKLEEWYQKQYFVLMLSIFIFAVFKLGVLLSTVFSCIRLRQRRQVLHTVTVKSIDHATNENMYGSGVREDHITAKYIQPDNYYSPRVRNPRIFTSKPNEII

Description

Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

Catalytic Activity

ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate

Similarity

Belongs to the tetraspanin (TM4SF) family.
Belongs to the CTP synthase family.

Uniprot

H9IVG0   A0A2A4K4M5   A0A2H1VDC6   A0A194PD23   A0A3S2NZD4   A0A194RLJ0   + More
A0A212FI16   A0A0L7LVL0   A0A182SEV8   A0A182W3P9   A0A023EQE6   A0A182YLZ4   A0A182RRD9   Q17D34   A0A182LN67   A0A182XAZ4   Q7QDT4   A0A182HX67   A0A1Q3FGF4   A0A182QPI8   A0A182NDI4   A0A182FM21   U5EX76   A0A084VTR7   A0A182IJ08   A0A182JWN9   A0A336MHF1   B0WVJ3   A0A182PUI8   D6W8H3   A0A1J1IIN1   A0A336KY22   A0A0M4E8N6   A0A0J9UKN3   A0A1W4XDW9   A0A1I8Q7V8   A0A1Y1KBZ6   A0A0L0C3W9   A0A2A3EKG1   U4UB82   A0A0A1WZW0   B4HH84   A0A088A4X2   B4PHW3   A0A0T6B8L0   A0A1A9XX71   B3MAN0   A0A1I8M1X7   A0A1B0AUW5   B4LNS3   A0A1W4UI57   A0A1A9Z0H7   B3NHH4   Q8IQK9   A0A1A9V2R0   Q4V3R4   A0A026W585   A0A0R3NNW6   A0A1B0FCD9   B4GI53   B5DZ48   A0A3L8DQX7   A0A0R3NTN9   B4KT74   B4MYH1   A0A3B0JAP4   B4JVI3   E2A5E6   A0A0C9R1H1   A0A0L7R5M4   E2BB46   A0A232FFR5   K7J7Z6   A0A0M8ZU68   A0A151JT85   A0A158NY22   A0A182UE64   A0A195ECI0   A0A151I588   N6UE05   A0A1S4EMK9   E0VHY1   A0A3Q0JH04   N6TR85   A0A226E8K7   A0A2P6L519  

EC Number

6.3.4.2

Pubmed

19121390    26354079    22118469    26227816    24945155    26483478    + More
25244985    17510324    20966253    12364791    14747013    17210077    24438588    18362917    19820115    22936249    28004739    26108605    23537049    25830018    17994087    17550304    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    24508170    15632085    30249741    20798317    28648823    20075255    21347285    20566863   

EMBL

BABH01001040    NWSH01000189    PCG78612.1    ODYU01001917    SOQ38791.1    KQ459606    + More
KPI91221.1    RSAL01000084    RVE48418.1    KQ460205    KPJ16851.1    AGBW02008449    OWR53366.1    JTDY01000008    KOB79475.1    JXUM01027703    JXUM01027704    JXUM01027705    GAPW01002280    GAPW01002279    KQ560798    JAC11318.1    KXJ80857.1    CH477300    EAT44287.1    AAAB01008849    EAA07108.4    APCN01005145    GFDL01008416    JAV26629.1    AXCN02001759    GANO01000200    JAB59671.1    ATLV01016453    KE525091    KFB41361.1    UFQT01001277    SSX29824.1    DS232127    EDS35600.1    KQ971312    EEZ98301.1    CVRI01000054    CRL00048.1    UFQS01001006    UFQT01001006    SSX08503.1    SSX28419.1    CP012524    ALC41121.1    CM002912    KMY99465.1    GEZM01086831    JAV58969.1    JRES01001007    KNC26189.1    KZ288219    PBC32217.1    KB632277    ERL91179.1    GBXI01009925    JAD04367.1    CH480815    EDW41409.1    CM000159    EDW94438.1    LJIG01009146    KRT83664.1    CH902618    EDV41317.1    JXJN01003777    JXJN01003778    CH940648    EDW60143.1    CH954178    EDV51700.1    AE014296    AAN11811.1    AAN11812.2    BT023292    AAY55708.1    KK107413    EZA51158.1    CM000071    KRT02492.1    CCAG010007972    CH479183    EDW36173.1    EDY69147.1    QOIP01000005    RLU22850.1    KRT02493.1    CH933808    EDW10586.1    CH963894    EDW77160.1    OUUW01000004    SPP79394.1    CH916375    EDV98451.1    GL436923    EFN71338.1    GBYB01001800    JAG71567.1    KQ414648    KOC66187.1    GL446901    EFN87137.1    NNAY01000312    OXU29298.1    KQ435844    KOX71240.1    KQ981972    KYN31634.1    ADTU01002930    KQ979074    KYN22816.1    KQ976434    KYM87159.1    APGK01026367    APGK01026368    KB740627    ENN79940.1    DS235172    EEB12987.1    APGK01008292    APGK01008293    KB737656    ENN82984.1    LNIX01000006    OXA53201.1    MWRG01001773    PRD33677.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000283053    UP000053240    UP000007151    + More
UP000037510    UP000075901    UP000075920    UP000069940    UP000249989    UP000076408    UP000075900    UP000008820    UP000075882    UP000076407    UP000007062    UP000075840    UP000075886    UP000075884    UP000069272    UP000030765    UP000075880    UP000075881    UP000002320    UP000075885    UP000007266    UP000183832    UP000092553    UP000192223    UP000095300    UP000037069    UP000242457    UP000030742    UP000001292    UP000005203    UP000002282    UP000092443    UP000007801    UP000095301    UP000092460    UP000008792    UP000192221    UP000092445    UP000008711    UP000000803    UP000078200    UP000053097    UP000001819    UP000092444    UP000008744    UP000279307    UP000009192    UP000007798    UP000268350    UP000001070    UP000000311    UP000053825    UP000008237    UP000215335    UP000002358    UP000053105    UP000078541    UP000005205    UP000075902    UP000078492    UP000078540    UP000019118    UP000079169    UP000009046    UP000198287   

PRIDE

H9IVG0    Q8IQK9    Q4V3R4   

Pfam

PF00335   Tetraspanin        + More
PF05625   PAXNEB
PF06418   CTP_synth_N
PF00117   GATase
PF02770   Acyl-CoA_dh_M
PF00441   Acyl-CoA_dh_1
PF02771   Acyl-CoA_dh_N

Interpro

IPR018499   Tetraspanin/Peripherin        + More
IPR008952   Tetraspanin_EC2_sf       
IPR000301   Tetraspanin       
IPR008728   Elongator_complex_protein_4       
IPR033828   GATase1_CTP_Synthase       
IPR004468   CTP_synthase       
IPR029062   Class_I_gatase-like       
IPR017456   CTP_synthase_N       
IPR017926   GATASE       
IPR027417   P-loop_NTPase       
IPR006089   Acyl-CoA_DH_CS       
IPR013786   AcylCoA_DH/ox_N       
IPR037069   AcylCoA_DH/ox_N_sf       
IPR036250   AcylCo_DH-like_C       
IPR006091   Acyl-CoA_Oxase/DH_cen-dom       
IPR009100   AcylCoA_DH/oxidase_NM_dom       
IPR034180   MCAD       
IPR009075   AcylCo_DH/oxidase_C       
IPR018503   Tetraspanin_CS       

SUPFAM

SSF48652   SSF48652        + More
SSF52540   SSF52540       
SSF52317   SSF52317       
SSF56645   SSF56645       
SSF47203   SSF47203       

Gene 3D

3.40.50.880     1.10.1450.10     1.10.540.10    

CDD

cd01746  GATase1_CTP_Synthase
cd01157  MCAD

ProteinModelPortal

H9IVG0   A0A2A4K4M5   A0A2H1VDC6   A0A194PD23   A0A3S2NZD4   A0A194RLJ0   + More
A0A212FI16   A0A0L7LVL0   A0A182SEV8   A0A182W3P9   A0A023EQE6   A0A182YLZ4   A0A182RRD9   Q17D34   A0A182LN67   A0A182XAZ4   Q7QDT4   A0A182HX67   A0A1Q3FGF4   A0A182QPI8   A0A182NDI4   A0A182FM21   U5EX76   A0A084VTR7   A0A182IJ08   A0A182JWN9   A0A336MHF1   B0WVJ3   A0A182PUI8   D6W8H3   A0A1J1IIN1   A0A336KY22   A0A0M4E8N6   A0A0J9UKN3   A0A1W4XDW9   A0A1I8Q7V8   A0A1Y1KBZ6   A0A0L0C3W9   A0A2A3EKG1   U4UB82   A0A0A1WZW0   B4HH84   A0A088A4X2   B4PHW3   A0A0T6B8L0   A0A1A9XX71   B3MAN0   A0A1I8M1X7   A0A1B0AUW5   B4LNS3   A0A1W4UI57   A0A1A9Z0H7   B3NHH4   Q8IQK9   A0A1A9V2R0   Q4V3R4   A0A026W585   A0A0R3NNW6   A0A1B0FCD9   B4GI53   B5DZ48   A0A3L8DQX7   A0A0R3NTN9   B4KT74   B4MYH1   A0A3B0JAP4   B4JVI3   E2A5E6   A0A0C9R1H1   A0A0L7R5M4   E2BB46   A0A232FFR5   K7J7Z6   A0A0M8ZU68   A0A151JT85   A0A158NY22   A0A182UE64   A0A195ECI0   A0A151I588   N6UE05   A0A1S4EMK9   E0VHY1   A0A3Q0JH04   N6TR85   A0A226E8K7   A0A2P6L519  

KEGG

101738445    no KO assigned | (RefSeq) CD151 antigen

GO

GO:0016021   GO:0033588   GO:0002098   GO:0005887   GO:0044210   GO:0003883   GO:0005524   GO:0006541   GO:0005739   GO:0006635   GO:0050660   GO:0070991   GO:0005802   GO:0030097   GO:0048471   GO:0006457   GO:0006950   GO:0051082   GO:0005216   GO:0006811   GO:0022891   GO:0003707   GO:0051537  

PANTHER

PTHR12896   PTHR11550  

Subcellular location

Membrane  

Length:

260

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

52.3581

Exp number, first 60 AAs:

29.45056

Total prob of N-in:

0.71998

POSSIBLE N-term signal

sequence

inside

1  -  11

TMhelix

12  -  34

outside

35  -  170

TMhelix

171  -  193

inside

194  -  260

 

 

Pi

198.579517

Theta

177.140755

Tajima's D

0.392082

CLR

0

CSRT

0.480025998700065

Interpretation

Uncertain